Conservation of cofitness between BT0738 and BT3759 in Bacteroides thetaiotaomicron VPI-5482

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0738 serine hydroxymethyltransferase (NCBI ptt file) 1.0 BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) 0.86 15
Bacteroides ovatus ATCC 8483 0.99 BACOVA_02446 glycine hydroxymethyltransferase 0.97 BACOVA_03589 N-acetyl-gamma-glutamyl-phosphate reductase 0.97 1
Phocaeicola vulgatus CL09T03C04 0.98 HMPREF1058_RS03800 serine hydroxymethyltransferase 0.89 HMPREF1058_RS08840 N-acetyl-gamma-glutamyl-phosphate reductase 0.70 65
Phocaeicola dorei CL03T12C01 0.97 ABI39_RS17420 serine hydroxymethyltransferase 0.89 ABI39_RS02970 N-acetyl-gamma-glutamyl-phosphate reductase 0.65 61
Bacteroides stercoris CC31F 0.96 HMPREF1181_RS15010 serine hydroxymethyltransferase 0.95 HMPREF1181_RS03450 N-acetyl-gamma-glutamyl-phosphate reductase low > 56
Parabacteroides merdae CL09T00C40 0.83 HMPREF1078_RS02145 serine hydroxymethyltransferase 0.79 HMPREF1078_RS10580 N-acetyl-gamma-glutamyl-phosphate reductase low > 61
Pontibacter actiniarum KMM 6156, DSM 19842 0.69 CA264_17045 serine hydroxymethyltransferase 0.54 CA264_06250 N-acetyl-gamma-glutamyl-phosphate reductase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.67 ABZR88_RS00640 serine hydroxymethyltransferase 0.63 ABZR88_RS15505 N-acetyl-gamma-glutamyl-phosphate reductase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.65 Echvi_1188 Glycine/serine hydroxymethyltransferase 0.50 Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) 0.88 25
Pedobacter sp. GW460-11-11-14-LB5 0.65 CA265_RS19165 serine hydroxymethyltransferase 0.63 CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.86 42
Shewanella amazonensis SB2B 0.54 Sama_1014 glyA serine hydroxymethyltransferase (RefSeq) 0.16 Sama_0256 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.90 22
Shewanella loihica PV-4 0.54 Shew_1185 glyA serine hydroxymethyltransferase (RefSeq) 0.18 Shew_0202 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.92 26
Marinobacter adhaerens HP15 0.54 HP15_489 glycine hydroxymethyltransferase 0.28 HP15_352 N-acetyl-gamma-glutamyl-phosphate reductase — —
Shewanella sp. ANA-3 0.54 Shewana3_1094 glyA serine hydroxymethyltransferase (RefSeq) 0.18 Shewana3_3905 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.90 40
Pseudomonas sp. RS175 0.53 PFR28_03786 Serine hydroxymethyltransferase 0.30 PFR28_04033 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas stutzeri RCH2 0.53 Psest_3404 Glycine/serine hydroxymethyltransferase 0.31 Psest_3639 N-acetyl-gamma-glutamyl-phosphate reductase, common form — —
Xanthomonas campestris pv. campestris strain 8004 0.53 Xcc-8004.4398.1 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.23 Xcc-8004.2322.1 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.74 34
Pseudomonas sp. S08-1 0.53 OH686_16230 Serine hydroxymethyltransferase 0.30 OH686_15195 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_15725 serine hydroxymethyltransferase 0.30 AO356_14490 N-acetyl-gamma-glutamyl-phosphate reductase — —
Shewanella oneidensis MR-1 0.53 SO3471 glyA serine hydroxymethyltransferase (NCBI ptt file) 0.17 SO0275 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI ptt file) 0.91 29
Pseudomonas fluorescens FW300-N2E2 0.53 Pf6N2E2_5082 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.30 Pf6N2E2_4836 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_2778 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.30 Pf1N1B4_2559 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Castellaniella sp019104865 MT123 0.53 ABCV34_RS06400 serine hydroxymethyltransferase 0.28 ABCV34_RS10590 N-acetyl-gamma-glutamyl-phosphate reductase — —
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS10715 serine hydroxymethyltransferase 0.22 ABZR86_RS08700 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.95 16
Pseudomonas fluorescens SBW25 0.53 PFLU_RS26195 serine hydroxymethyltransferase 0.30 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_14020 serine hydroxymethyltransferase 0.30 AO353_07155 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS26195 serine hydroxymethyltransferase 0.30 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase — —
Caulobacter crescentus NA1000 Δfur 0.53 CCNA_01419 serine hydroxymethyltransferase 0.13 CCNA_01442 N-acetyl-gamma-glutamyl-phosphate reductase low > 67
Caulobacter crescentus NA1000 0.53 CCNA_01419 serine hydroxymethyltransferase 0.13 CCNA_01442 N-acetyl-gamma-glutamyl-phosphate reductase — —
Kangiella aquimarina DSM 16071 0.53 B158DRAFT_1908 Glycine/serine hydroxymethyltransferase 0.21 B158DRAFT_1979 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 40
Pseudomonas putida KT2440 0.53 PP_0671 serine hydroxymethyltransferase 0.30 PP_0432 N-acetyl-gamma-glutamyl-phosphate reductase 1 — —
Lysobacter sp. OAE881 0.53 ABIE51_RS04620 serine hydroxymethyltransferase 0.25 ABIE51_RS13385 N-acetyl-gamma-glutamyl-phosphate reductase 0.76 45
Dickeya dianthicola ME23 0.53 DZA65_RS16775 serine hydroxymethyltransferase 0.21 DZA65_RS00935 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas simiae WCS417 0.52 PS417_24280 serine hydroxymethyltransferase 0.30 PS417_25660 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas fluorescens GW456-L13 0.52 PfGW456L13_1451 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.30 PfGW456L13_1233 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Dickeya dadantii 3937 0.52 DDA3937_RS15600 serine hydroxymethyltransferase 0.21 DDA3937_RS20350 N-acetyl-gamma-glutamyl-phosphate reductase — —
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_11440 glyA serine hydroxymethyltransferase 0.21 OKGIIK_09435 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 52
Pseudomonas syringae pv. syringae B728a ΔmexB 0.52 Psyr_4270 serine hydroxymethyltransferase 0.30 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase — —
Synechococcus elongatus PCC 7942 0.52 Synpcc7942_0282 glyA serine hydroxymethyltransferase 0.20 Synpcc7942_1433 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas syringae pv. syringae B728a 0.52 Psyr_4270 serine hydroxymethyltransferase 0.30 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase — —
Dickeya dianthicola 67-19 0.52 HGI48_RS15700 serine hydroxymethyltransferase 0.22 HGI48_RS00875 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pantoea sp. MT58 0.52 IAI47_04960 serine hydroxymethyltransferase 0.23 IAI47_00905 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pectobacterium carotovorum WPP14 0.52 HER17_RS05950 serine hydroxymethyltransferase 0.21 HER17_RS20630 N-acetyl-gamma-glutamyl-phosphate reductase — —
Desulfovibrio vulgaris Hildenborough JW710 0.52 DVU1203 glyA serine hydroxymethyltransferase (TIGR) 0.25 DVU0492 argC N-acetyl-gamma-glutamyl-phosphate reductase (TIGR) — —
Ralstonia solanacearum IBSBF1503 0.52 RALBFv3_RS12895 serine hydroxymethyltransferase 0.14 RALBFv3_RS19930 N-acetyl-gamma-glutamyl-phosphate reductase — —
Ralstonia solanacearum UW163 0.52 UW163_RS00670 serine hydroxymethyltransferase 0.14 UW163_RS19245 N-acetyl-gamma-glutamyl-phosphate reductase — —
Rhodanobacter denitrificans MT42 0.51 LRK55_RS04400 serine hydroxymethyltransferase 0.20 LRK55_RS02140 N-acetyl-gamma-glutamyl-phosphate reductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.51 LRK54_RS04625 serine hydroxymethyltransferase 0.20 LRK54_RS02385 N-acetyl-gamma-glutamyl-phosphate reductase 0.64 31
Erwinia tracheiphila SCR3 0.51 LU632_RS17915 serine hydroxymethyltransferase 0.21 LU632_RS19615 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Rahnella sp. WP5 0.51 EX31_RS20585 serine hydroxymethyltransferase 0.21 EX31_RS14190 N-acetyl-gamma-glutamyl-phosphate reductase — —
Desulfovibrio vulgaris Miyazaki F 0.51 DvMF_3097 glyA serine hydroxymethyltransferase (RefSeq) 0.24 DvMF_1717 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) — —
Acidovorax sp. GW101-3H11 0.51 Ac3H11_2921 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.14 Ac3H11_2950 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Acinetobacter radioresistens SK82 0.51 MPMX26_02049 Serine hydroxymethyltransferase 0.30 MPMX26_01281 N-acetyl-gamma-glutamyl-phosphate reductase — —
Serratia liquefaciens MT49 0.50 IAI46_19395 serine hydroxymethyltransferase 0.22 IAI46_24515 N-acetyl-gamma-glutamyl-phosphate reductase — —
Herbaspirillum seropedicae SmR1 0.50 HSERO_RS06140 serine hydroxymethyltransferase 0.26 HSERO_RS19210 N-acetyl-gamma-glutamyl-phosphate reductase — —
Paraburkholderia sabiae LMG 24235 0.50 QEN71_RS26235 serine hydroxymethyltransferase 0.14 QEN71_RS33725 N-acetyl-gamma-glutamyl-phosphate reductase low > 153
Escherichia coli ECOR27 0.50 NOLOHH_13185 glyA serine hydroxymethyltransferase 0.20 NOLOHH_05730 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 57
Escherichia coli Nissle 1917 0.50 ECOLIN_RS14440 serine hydroxymethyltransferase 0.19 ECOLIN_RS22845 N-acetyl-gamma-glutamyl-phosphate reductase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.50 GFF5152 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.13 GFF2503 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Escherichia coli ECRC62 0.50 BNILDI_11985 glyA serine hydroxymethyltransferase 0.20 BNILDI_05795 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_01156 Serine hydroxymethyltransferase 0.20 OHPLBJKB_04092 N-acetyl-gamma-glutamyl-phosphate reductase low > 73
Escherichia coli ECOR38 0.50 HEPCGN_20655 glyA serine hydroxymethyltransferase 0.20 HEPCGN_12230 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 85
Escherichia coli BW25113 0.50 b2551 glyA serine hydroxymethyltransferase (NCBI) 0.20 b3958 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) — —
Escherichia fergusonii Becca 0.50 EFB2_01345 Serine hydroxymethyltransferase 0.19 EFB2_04656 N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli BL21 0.50 ECD_02443 serine hydroxymethyltransferase 0.20 ECD_03843 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding low > 60
Escherichia coli ECRC101 0.50 MCAODC_12040 glyA serine hydroxymethyltransferase 0.19 MCAODC_04085 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli ECRC99 0.50 KEDOAH_06710 glyA serine hydroxymethyltransferase 0.19 KEDOAH_14575 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli ECRC101 0.50 OKFHMN_21510 glyA serine hydroxymethyltransferase 0.19 OKFHMN_13585 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF2447 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.22 GFF2344 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Escherichia coli ECRC102 0.50 NIAGMN_19280 glyA serine hydroxymethyltransferase 0.19 NIAGMN_11335 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli ECRC98 0.50 JDDGAC_25175 glyA serine hydroxymethyltransferase 0.19 JDDGAC_17210 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Enterobacter sp. TBS_079 0.49 MPMX20_03420 Serine hydroxymethyltransferase 0.22 MPMX20_04522 N-acetyl-gamma-glutamyl-phosphate reductase — —
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_04820 serine hydroxymethyltransferase 0.21 CSW01_13380 N-acetyl-gamma-glutamyl-phosphate reductase low > 62
Klebsiella michiganensis M5al 0.49 BWI76_RS21225 serine hydroxymethyltransferase 0.20 BWI76_RS00845 N-acetyl-gamma-glutamyl-phosphate reductase — —
Enterobacter asburiae PDN3 0.49 EX28DRAFT_0099 Glycine/serine hydroxymethyltransferase 0.21 EX28DRAFT_4420 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_2113 Glycine hydroxymethyltransferase (RefSeq) 0.18 Dshi_1759 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) — —
Variovorax sp. OAS795 0.49 ABID97_RS17890 serine hydroxymethyltransferase 0.12 ABID97_RS02250 N-acetyl-gamma-glutamyl-phosphate reductase — —
Alteromonas macleodii MIT1002 0.49 MIT1002_02702 Serine hydroxymethyltransferase 0.19 MIT1002_00471 N-acetyl-gamma-glutamyl-phosphate reductase 0.94 15
Bosea sp. OAE506 0.49 ABIE41_RS19780 serine hydroxymethyltransferase 0.24 ABIE41_RS15755 N-acetyl-gamma-glutamyl-phosphate reductase — —
Phaeobacter inhibens DSM 17395 0.49 PGA1_c11870 serine hydroxymethyltransferase GlyA 0.18 PGA1_c17050 N-acetyl-gamma-glutamyl-phosphate reductase ArgC 0.69 53
Variovorax sp. SCN45 0.48 GFF560 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.12 GFF5404 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.48 A4249_RS06040 serine hydroxymethyltransferase 0.15 A4249_RS05920 N-acetyl-gamma-glutamyl-phosphate reductase — —
Rhodospirillum rubrum S1H 0.48 Rru_A1827 Glycine hydroxymethyltransferase (NCBI) 0.23 Rru_A2421 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.48 Rv0070c Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) 0.19 Rv1652 Probable N-acetyl-gamma-glutamyl-phoshate reductase ArgC — —
Azospirillum sp. SherDot2 0.46 MPMX19_00727 Serine hydroxymethyltransferase 2 0.26 MPMX19_03843 N-acetyl-gamma-glutamyl-phosphate reductase — —
Magnetospirillum magneticum AMB-1 0.46 AMB_RS11815 serine hydroxymethyltransferase 0.27 AMB_RS09075 N-acetyl-gamma-glutamyl-phosphate reductase — —
Azospirillum brasilense Sp245 0.45 AZOBR_RS10015 serine hydroxymethyltransferase 0.26 AZOBR_RS07795 N-acetyl-gamma-glutamyl-phosphate reductase — —

Not shown: 13 genomes with orthologs for BT0738 only; 3 genomes with orthologs for BT3759 only