Conservation of cofitness between BT0650 and BT3164 in Bacteroides thetaiotaomicron VPI-5482

84 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 1.0 BT3164 quinolinate synthetase A (NCBI ptt file) 0.47 11
Bacteroides ovatus ATCC 8483 0.98 BACOVA_02358 thiamine biosynthesis protein ThiC 0.98 BACOVA_02839 quinolinate synthetase complex, A subunit 0.80 16
Bacteroides stercoris CC31F 0.92 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.93 HMPREF1181_RS01920 quinolinate synthase NadA — —
Phocaeicola vulgatus CL09T03C04 0.87 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.81 HMPREF1058_RS11230 quinolinate synthase NadA — —
Phocaeicola dorei CL03T12C01 0.86 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.80 ABI39_RS05755 quinolinate synthase NadA — —
Parabacteroides merdae CL09T00C40 0.72 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.77 HMPREF1078_RS06555 quinolinate synthase NadA — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.68 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.65 ABZR88_RS20650 quinolinate synthase NadA — —
Pedobacter sp. GW460-11-11-14-LB5 0.66 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.64 CA265_RS21180 quinolinate synthase — —
Herbaspirillum seropedicae SmR1 0.65 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.42 HSERO_RS11065 quinolinate synthetase 0.32 76
Acinetobacter radioresistens SK82 0.65 MPMX26_00180 Phosphomethylpyrimidine synthase 0.42 MPMX26_02602 Quinolinate synthase A low > 36
Marinobacter adhaerens HP15 0.65 HP15_453 thiamine biosynthesis protein thiC 0.44 HP15_2032 quinolinate synthetase complex, A subunit — —
Shewanella amazonensis SB2B 0.65 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.41 Sama_1712 quinolinate synthetase (RefSeq) — —
Shewanella loihica PV-4 0.65 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.41 Shew_1928 quinolinate synthetase (RefSeq) — —
Dechlorosoma suillum PS 0.65 Dsui_0422 thiamine biosynthesis protein ThiC 0.24 Dsui_1043 quinolinate synthetase complex, A subunit — —
Rhodanobacter sp. FW510-T8 0.64 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.36 OKGIIK_00930 nadA quinolinate synthase NadA low > 52
Dickeya dadantii 3937 0.64 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.39 DDA3937_RS06545 quinolinate synthase NadA 0.84 11
Pectobacterium carotovorum WPP14 0.64 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.40 HER17_RS14820 quinolinate synthase NadA 0.81 35
Pseudomonas sp. S08-1 0.64 OH686_15885 phosphomethylpyrimidine synthase 0.44 OH686_19190 quinolinate synthetase complex, A subunit 0.78 38
Pseudomonas putida KT2440 0.64 PP_4922 Phosphomethylpyrimidine synthase 0.44 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit 0.67 7
Pseudomonas stutzeri RCH2 0.64 Psest_0477 thiamine biosynthesis protein ThiC 0.45 Psest_1509 quinolinate synthetase complex, A subunit 0.67 4
Paraburkholderia graminis OAS925 0.64 ABIE53_002857 phosphomethylpyrimidine synthase 0.41 ABIE53_003294 quinolinate synthase 0.38 83
Paraburkholderia sabiae LMG 24235 0.64 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.42 QEN71_RS03060 quinolinate synthase NadA 0.87 5
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.40 BPHYT_RS15650 quinolinate synthetase 0.52 76
Ralstonia sp. UNC404CL21Col 0.64 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.41 ABZR87_RS00355 quinolinate synthase NadA 0.54 59
Castellaniella sp019104865 MT123 0.64 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.39 ABCV34_RS03700 quinolinate synthase NadA low > 48
Dickeya dianthicola ME23 0.64 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.40 DZA65_RS06945 quinolinate synthase NadA 0.88 6
Escherichia coli ECOR27 0.63 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.39 NOLOHH_23190 nadA quinolinate synthase NadA low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.63 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.38 OHPLBJKB_02963 Quinolinate synthase A low > 73
Escherichia coli BW25113 0.63 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.39 b0750 nadA quinolinate synthetase (NCBI) 0.64 12
Cupriavidus basilensis FW507-4G11 0.63 RR42_RS01290 thiamine biosynthesis protein ThiC 0.40 RR42_RS17020 quinolinate synthetase low > 128
Escherichia coli ECRC62 0.63 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.39 BNILDI_21185 nadA quinolinate synthase NadA — —
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.42 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) low > 103
Escherichia coli ECRC101 0.63 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.39 MCAODC_25980 nadA quinolinate synthase NadA — —
Escherichia coli ECRC101 0.63 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.39 OKFHMN_06760 nadA quinolinate synthase NadA — —
Escherichia fergusonii Becca 0.63 EFB2_04617 Phosphomethylpyrimidine synthase 0.39 EFB2_03356 Quinolinate synthase A low > 86
Escherichia coli ECRC102 0.63 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.39 NIAGMN_04810 nadA quinolinate synthase NadA — —
Pseudomonas simiae WCS417 0.63 PS417_02355 thiamine biosynthesis protein ThiC 0.43 PS417_22385 quinolinate synthase A low > 88
Escherichia coli Nissle 1917 0.63 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.39 ECOLIN_RS03990 quinolinate synthase NadA low > 52
Escherichia coli ECRC98 0.63 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.39 JDDGAC_10415 nadA quinolinate synthase NadA — —
Escherichia coli ECRC99 0.63 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.39 KEDOAH_21205 nadA quinolinate synthase NadA — —
Escherichia coli ECOR38 0.63 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.39 HEPCGN_01515 nadA quinolinate synthase NadA low > 85
Rahnella sp. WP5 0.63 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.38 EX31_RS23525 quinolinate synthase NadA low > 89
Serratia liquefaciens MT49 0.63 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.39 IAI46_06380 quinolinate synthase NadA low > 86
Pseudomonas fluorescens FW300-N2C3 0.63 AO356_08810 thiamine biosynthesis protein ThiC 0.42 AO356_18145 quinolinate synthase A 0.44 3
Ralstonia solanacearum GMI1000 0.63 RS_RS00555 phosphomethylpyrimidine synthase 0.43 RS_RS12295 quinolinate synthase 0.63 10
Dickeya dianthicola 67-19 0.63 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.40 HGI48_RS06595 quinolinate synthase NadA 0.79 43
Pantoea sp. MT58 0.63 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.38 IAI47_13635 quinolinate synthase NadA low > 76
Pseudomonas fluorescens SBW25 0.63 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.43 PFLU_RS24025 quinolinate synthase NadA 0.70 87
Ralstonia solanacearum PSI07 0.63 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.41 RPSI07_RS12650 quinolinate synthase NadA low > 81
Escherichia coli BL21 0.63 ECD_03871 phosphomethylpyrimidine synthase 0.39 ECD_00703 quinolinate synthase, subunit A low > 60
Pseudomonas fluorescens SBW25-INTG 0.63 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.43 PFLU_RS24025 quinolinate synthase NadA 0.51 6
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.41 RALBFv3_RS04735 quinolinate synthase NadA low > 76
Pseudomonas syringae pv. syringae B728a 0.63 Psyr_0544 hydroxymethylpyrimidine synthase 0.44 Psyr_1542 quinolinate synthetase 0.75 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.63 Psyr_0544 hydroxymethylpyrimidine synthase 0.44 Psyr_1542 quinolinate synthetase 0.48 24
Ralstonia solanacearum UW163 0.63 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.41 UW163_RS08935 quinolinate synthase NadA — —
Alteromonas macleodii MIT1002 0.63 MIT1002_00097 Phosphomethylpyrimidine synthase 0.43 MIT1002_01344 Quinolinate synthase A — —
Pseudomonas sp. RS175 0.63 PFR28_05091 Phosphomethylpyrimidine synthase 0.42 PFR28_03388 Quinolinate synthase A 0.73 5
Enterobacter asburiae PDN3 0.63 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.39 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) 0.60 22
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.63 GFF4198 Thiamin biosynthesis protein ThiC 0.39 GFF4 Quinolinate synthetase (EC 2.5.1.72) — —
Enterobacter sp. TBS_079 0.63 MPMX20_00217 Phosphomethylpyrimidine synthase 0.39 MPMX20_01377 Quinolinate synthase A low > 85
Pseudomonas fluorescens FW300-N2E3 0.63 AO353_13010 thiamine biosynthesis protein ThiC 0.43 AO353_03525 quinolinate synthase A 0.38 34
Pseudomonas fluorescens GW456-L13 0.63 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.43 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) low > 87
Pseudomonas fluorescens FW300-N1B4 0.63 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.42 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) 0.45 19
Magnetospirillum magneticum AMB-1 0.63 AMB_RS01125 phosphomethylpyrimidine synthase 0.55 AMB_RS19660 quinolinate synthase NadA — —
Agrobacterium fabrum C58 0.63 Atu2569 thiamine biosynthesis protein 0.38 Atu4098 quinolinate synthetase 0.86 6
Phaeobacter inhibens DSM 17395 0.62 PGA1_c09110 thiamine biosynthesis protein ThiC 0.40 PGA1_c27790 quinolinate synthetase A 0.26 56
Shewanella sp. ANA-3 0.62 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.39 Shewana3_2128 quinolinate synthetase (RefSeq) — —
Sinorhizobium meliloti 1021 0.62 SM_b20615 thiamine biosynthesis protein ThiC 0.34 SMc02601 quinolinate synthetase low > 103
Klebsiella michiganensis M5al 0.62 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.38 BWI76_RS08580 quinolinate synthetase 0.62 8
Shewanella oneidensis MR-1 0.62 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.41 SO2342 nadA quinolinate synthetase complex, subunit A (NCBI ptt file) low > 76
Azospirillum brasilense Sp245 0.62 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.38 AZOBR_RS18690 quinolinate synthetase low > 97
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.40 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) 0.82 26
Brevundimonas sp. GW460-12-10-14-LB2 0.61 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.37 A4249_RS00620 quinolinate synthase NadA low > 48
Vibrio cholerae E7946 ATCC 55056 0.61 CSW01_00335 phosphomethylpyrimidine synthase 0.41 CSW01_09180 quinolinate synthase low > 62
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.38 CCNA_03006 quinolinate synthetase A — —
Caulobacter crescentus NA1000 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.38 CCNA_03006 quinolinate synthetase A — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.60 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.40 GFF1216 Quinolinate synthetase (EC 2.5.1.72) low > 90
Sphingomonas koreensis DSMZ 15582 0.60 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.54 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) — —
Azospirillum sp. SherDot2 0.60 MPMX19_00336 Phosphomethylpyrimidine synthase 0.37 MPMX19_05670 Quinolinate synthase A low > 112
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.41 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) — —
Variovorax sp. SCN45 0.59 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.40 GFF2575 Quinolinate synthetase (EC 2.5.1.72) low > 127
Variovorax sp. OAS795 0.59 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.41 ABID97_RS07415 quinolinate synthase NadA low > 91
Rhodopseudomonas palustris CGA009 0.58 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.35 TX73_005425 quinolinate synthase NadA — —
Rhodospirillum rubrum S1H 0.57 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.38 Rru_A1434 Quinolinate synthetase A (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.49 Rv0423c Probable thiamine biosynthesis protein ThiC 0.39 Rv1594 Probable quinolinate synthetase NadA — —

Not shown: 9 genomes with orthologs for BT0650 only; 9 genomes with orthologs for BT3164 only