| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b4235 | pmbA | predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) | 1.0 | b4175 | hflC | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | 0.28 | 16 |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_16230 | pmbA | metalloprotease PmbA | 1.00 | KEDOAH_15915 | hflC | protease modulator HflC | — | — |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_10125 | pmbA | metalloprotease PmbA | 1.00 | HEPCGN_10470 | hflC | protease modulator HflC | low | > 85 |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_15565 | pmbA | metalloprotease PmbA | 1.00 | JDDGAC_15880 | hflC | protease modulator HflC | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_04185 | pmbA | metalloprotease PmbA | 1.00 | NOLOHH_04505 | hflC | protease modulator HflC | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_09775 | pmbA | metalloprotease PmbA | 1.00 | NIAGMN_10090 | hflC | protease modulator HflC | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_11925 | pmbA | metalloprotease PmbA | 1.00 | OKFHMN_12240 | hflC | protease modulator HflC | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_02430 | pmbA | metalloprotease PmbA | 1.00 | MCAODC_02755 | hflC | protease modulator HflC | — | — |
| Escherichia coli ECRC62 | 1.00 | BNILDI_07325 | pmbA | metalloprotease PmbA | 1.00 | BNILDI_06985 | hflC | protease modulator HflC | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_03800 | | Metalloprotease PmbA | 1.00 | OHPLBJKB_03867 | | Modulator of FtsH protease HflC | low | > 73 |
| Escherichia coli BL21 | 1.00 | ECD_04103 | | putative antibiotic peptide MccB17 maturation peptidase | 1.00 | ECD_04042 | | HflB protease modulator specific for phage lambda cII repressor | low | > 60 |
| Escherichia fergusonii Becca | 0.99 | EFB2_04298 | | Metalloprotease PmbA | 1.00 | EFB2_04360 | | Modulator of FtsH protease HflC | low | > 86 |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS24570 | | metalloprotease PmbA | 1.00 | ECOLIN_RS24245 | | protease modulator HflC | — | — |
| Enterobacter sp. TBS_079 | 0.97 | MPMX20_00517 | | Metalloprotease PmbA | 0.87 | MPMX20_00456 | | Modulator of FtsH protease HflC | 0.27 | 43 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.97 | GFF904 | | TldE protein, part of TldE/TldD proteolytic complex | 0.89 | GFF828 | | HflC protein | low | > 78 |
| Enterobacter asburiae PDN3 | 0.96 | EX28DRAFT_3422 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.85 | EX28DRAFT_3372 | | HflC protein | low | > 76 |
| Klebsiella michiganensis M5al | 0.94 | BWI76_RS02850 | | metalloprotease PmbA | 0.87 | BWI76_RS02550 | | protease modulator HflC | low | > 92 |
| Serratia liquefaciens MT49 | 0.86 | IAI46_22575 | | metalloprotease PmbA | 0.79 | IAI46_01640 | | protease modulator HflC | low | > 86 |
| Rahnella sp. WP5 | 0.85 | EX31_RS12320 | | metalloprotease PmbA | 0.79 | EX31_RS08805 | | protease modulator HflC | low | > 89 |
| Pectobacterium carotovorum WPP14 | 0.84 | HER17_RS20090 | | metalloprotease PmbA | 0.79 | HER17_RS02600 | | protease modulator HflC | low | > 75 |
| Pantoea sp. MT58 | 0.84 | IAI47_02765 | | metalloprotease PmbA | 0.82 | IAI47_02605 | | protease modulator HflC | low | > 76 |
| Erwinia tracheiphila SCR3 | 0.81 | LU632_RS02145 | pmbA | metalloprotease PmbA | 0.83 | LU632_RS02070 | hflC | protease modulator HflC | low | > 74 |
| Dickeya dadantii 3937 | 0.81 | DDA3937_RS01500 | | metalloprotease PmbA | 0.74 | DDA3937_RS18595 | | protease modulator HflC | — | — |
| Dickeya dianthicola 67-19 | 0.81 | HGI48_RS01415 | | metalloprotease PmbA | 0.74 | HGI48_RS18530 | | protease modulator HflC | low | > 71 |
| Dickeya dianthicola ME23 | 0.81 | DZA65_RS01480 | | metalloprotease PmbA | 0.74 | DZA65_RS19665 | | protease modulator HflC | low | > 75 |
| Vibrio cholerae E7946 ATCC 55056 | 0.64 | CSW01_12845 | | metalloprotease PmbA | 0.52 | CSW01_01850 | | protease modulator HflC | low | > 62 |
| Shewanella amazonensis SB2B | 0.59 | Sama_0482 | | PmbA protein (RefSeq) | 0.48 | Sama_3022 | | hflC protein (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_3631 | | microcin-processing peptidase 1 (RefSeq) | 0.49 | Shewana3_0600 | | HflC protein (RefSeq) | 0.35 | 67 |
| Shewanella oneidensis MR-1 | 0.59 | SO4078 | pmbA | pmba protein (NCBI ptt file) | 0.49 | SO0606 | hflC | hflC protein (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.57 | Shew_0416 | | peptidase U62, modulator of DNA gyrase (RefSeq) | 0.47 | Shew_0569 | | HflC protein (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.54 | MIT1002_00230 | | peptidase PmbA | 0.49 | MIT1002_03785 | | Modulator of FtsH protease HflC | low | > 70 |
| Pseudomonas sp. RS175 | 0.48 | PFR28_00163 | | Metalloprotease PmbA | 0.28 | PFR28_05124 | | Modulator of FtsH protease HflC | low | > 88 |
| Pseudomonas fluorescens SBW25 | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | 0.30 | PFLU_RS02585 | | protease modulator HflC | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | 0.30 | PFLU_RS02585 | | protease modulator HflC | 0.35 | 33 |
| Pseudomonas fluorescens FW300-N2E2 | 0.48 | Pf6N2E2_3278 | | TldE protein, part of TldE/TldD proteolytic complex | 0.31 | Pf6N2E2_3611 | | HflC protein | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.48 | AO356_07085 | | peptidase PmbA | 0.31 | AO356_08640 | | membrane protease HflC | 0.46 | 2 |
| Pseudomonas simiae WCS417 | 0.47 | PS417_04295 | | peptidase PmbA | 0.28 | PS417_02505 | | membane protease HflC | — | — |
| Pseudomonas putida KT2440 | 0.47 | PP_0942 | | regulatory protease | 0.30 | PP_4891 | | integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.47 | Pf1N1B4_1090 | | TldE protein, part of TldE/TldD proteolytic complex | 0.32 | Pf1N1B4_1409 | | HflC protein | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_05205 | | peptidase PmbA | 0.31 | AO353_13160 | | membrane protease HflC | low | > 101 |
| Pseudomonas fluorescens GW456-L13 | 0.47 | PfGW456L13_5024 | | TldE protein, part of TldE/TldD proteolytic complex | 0.31 | PfGW456L13_151 | | HflC protein | low | > 87 |
| Pseudomonas syringae pv. syringae B728a | 0.46 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | 0.31 | Psyr_0575 | | protease FtsH subunit HflC | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.46 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | 0.31 | Psyr_0575 | | protease FtsH subunit HflC | low | > 86 |
| Herbaspirillum seropedicae SmR1 | 0.46 | HSERO_RS09265 | | peptidase C69 | 0.28 | HSERO_RS14760 | | membrane protein | low | > 78 |
| Pseudomonas stutzeri RCH2 | 0.45 | Psest_3318 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.30 | Psest_0686 | | Membrane protease subunits, stomatin/prohibitin homologs | — | — |
| Variovorax sp. OAS795 | 0.45 | ABID97_RS20695 | | metalloprotease PmbA | 0.24 | ABID97_RS14265 | | protease modulator HflC | 0.40 | 59 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.45 | Xcc-8004.1885.1 | | TldE protein, part of TldE/TldD proteolytic complex | 0.29 | Xcc-8004.3954.1 | | HflC protein | low | > 74 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS21700 | | metalloprotease PmbA | 0.30 | ABZR86_RS08350 | | protease modulator HflC | low | > 74 |
| Pseudomonas sp. S08-1 | 0.45 | OH686_08570 | | TldE protein, part of TldE/TldD proteolytic complex | 0.29 | OH686_09455 | | HflC protein | low | > 80 |
| Rhodanobacter sp. FW510-T8 | 0.45 | OKGIIK_10260 | pmbA | metalloprotease PmbA | 0.33 | OKGIIK_06645 | hflC | protease modulator HflC | 0.69 | 42 |
| Variovorax sp. SCN45 | 0.45 | GFF4697 | | TldE protein, part of TldE/TldD proteolytic complex | 0.23 | GFF1003 | | HflC protein | 0.82 | 49 |
| Rhodanobacter denitrificans MT42 | 0.44 | LRK55_RS03125 | | metalloprotease PmbA | 0.30 | LRK55_RS00385 | | protease modulator HflC | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.44 | LRK54_RS03375 | | metalloprotease PmbA | 0.30 | LRK54_RS00615 | | protease modulator HflC | low | > 59 |
| Dechlorosoma suillum PS | 0.44 | Dsui_1234 | | putative Zn-dependent protease-like protein | 0.33 | Dsui_3134 | | membrane protease subunit, stomatin/prohibitin | — | — |
| Acidovorax sp. GW101-3H11 | 0.44 | Ac3H11_3262 | | TldE protein, part of TldE/TldD proteolytic complex | 0.25 | Ac3H11_1802 | | HflC protein | low | > 79 |
| Ralstonia solanacearum UW163 | 0.43 | UW163_RS15845 | | metalloprotease PmbA | 0.30 | UW163_RS12780 | | protease modulator HflC | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.43 | RALBFv3_RS13965 | | metalloprotease PmbA | 0.30 | RALBFv3_RS15315 | | protease modulator HflC | — | — |
| Ralstonia sp. UNC404CL21Col | 0.43 | ABZR87_RS09660 | | metalloprotease PmbA | 0.28 | ABZR87_RS10955 | | protease modulator HflC | low | > 80 |
| Paraburkholderia graminis OAS925 | 0.43 | ABIE53_003116 | | PmbA protein | 0.24 | ABIE53_002734 | | membrane protease subunit HflC | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_04304 | | microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 | 0.22 | H281DRAFT_00524 | | protease FtsH subunit HflC | — | — |
| Ralstonia solanacearum PSI07 | 0.43 | RPSI07_RS19505 | | metalloprotease PmbA | 0.30 | RPSI07_RS18060 | | protease modulator HflC | low | > 81 |
| Paraburkholderia sabiae LMG 24235 | 0.43 | QEN71_RS04270 | | metalloprotease PmbA | 0.22 | QEN71_RS06015 | | protease modulator HflC | low | > 153 |
| Kangiella aquimarina DSM 16071 | 0.43 | B158DRAFT_2075 | | microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 | 0.35 | B158DRAFT_1955 | | HflC protein | low | > 40 |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS14705 | | peptidase C69 | 0.20 | BPHYT_RS12540 | | membrane protein | — | — |
| Castellaniella sp019104865 MT123 | 0.42 | ABCV34_RS10610 | | metalloprotease PmbA | 0.27 | ABCV34_RS02665 | | protease modulator HflC | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.41 | GFF3655 | | TldE protein, part of TldE/TldD proteolytic complex | 0.20 | GFF4855 | | HflC protein | low | > 90 |
| Lysobacter sp. OAE881 | 0.41 | ABIE51_RS06805 | | metalloprotease PmbA | 0.29 | ABIE51_RS06555 | | protease modulator HflC | low | > 62 |
| Ralstonia solanacearum GMI1000 | 0.41 | RS_RS04700 | | metalloprotease PmbA | 0.30 | RS_RS06125 | | protease modulator HflC | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.41 | RR42_RS14750 | | peptidase PMbA | 0.29 | RR42_RS13100 | | membrane protein | — | — |
| Azospirillum brasilense Sp245 | 0.34 | AZOBR_RS11930 | | modulator protein | 0.26 | AZOBR_RS06525 | | membrane protein | low | > 97 |
| Azospirillum sp. SherDot2 | 0.34 | MPMX19_01886 | | Metalloprotease PmbA | 0.29 | MPMX19_01250 | | Modulator of FtsH protease HflC | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.30 | Ga0059261_0810 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.15 | Ga0059261_1381 | | Membrane protease subunits, stomatin/prohibitin homologs | low | > 68 |
| Magnetospirillum magneticum AMB-1 | 0.29 | AMB_RS22120 | | TldD/PmbA family protein | 0.28 | AMB_RS17655 | | protease modulator HflC | — | — |
| Rhodopseudomonas palustris CGA009 | 0.29 | TX73_005930 | | TldD/PmbA family protein | 0.28 | TX73_018075 | | protease modulator HflC | low | > 86 |
| Rhodospirillum rubrum S1H | 0.29 | Rru_A0575 | | Peptidase U62, modulator of DNA gyrase (NCBI) | 0.27 | Rru_A2202 | | HflC (NCBI) | — | — |
| Sinorhizobium meliloti 1021 | 0.28 | SMc00897 | | PMBA protein | 0.23 | SMc01440 | | hydrolase serine protease transmembrane protein | low | > 103 |
| Agrobacterium fabrum C58 | 0.27 | Atu0693 | | PmbA/TldD related protein | 0.26 | Atu2044 | | HFLC protein | low | > 89 |
| Phaeobacter inhibens DSM 17395 | 0.27 | PGA1_c33480 | | protein PmbA | 0.29 | PGA1_c23700 | | protein HflC | — | — |
| Rhizobium sp. OAE497 | 0.26 | ABIE40_RS03780 | | TldD/PmbA family protein | 0.21 | ABIE40_RS11530 | | protease modulator HflC | low | > 107 |
| Dinoroseobacter shibae DFL-12 | 0.26 | Dshi_0064 | | peptidase U62 modulator of DNA gyrase (RefSeq) | 0.28 | Dshi_2735 | | HflC protein (RefSeq) | low | > 64 |
Not shown: 9 genomes with orthologs for b4235 only; 5 genomes with orthologs for b4175 only