Conservation of cofitness between b2290 and b3939 in Escherichia coli BW25113

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2290 yfbQ aspartate aminotransferase (NCBI) 1.0 b3939 metB cystathionine gamma-synthase (NCBI) 0.64 5
Escherichia fergusonii Becca 1.00 EFB2_01568 Glutamate-pyruvate aminotransferase AlaA 1.00 EFB2_04679 Cystathionine gamma-synthase low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS13295 alanine transaminase AlaA 0.99 ECOLIN_RS22725 cystathionine gamma-synthase 0.59 14
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01415 Glutamate-pyruvate aminotransferase AlaA 1.00 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli ECOR38 1.00 HEPCGN_22030 alaA alanine transaminase AlaA 1.00 HEPCGN_12345 metB cystathionine gamma-synthase low > 85
Escherichia coli BL21 1.00 ECD_02215 glutamate-pyruvate aminotransferase; glutamic-pyruvic transaminase (GPT); alanine transaminase 1.00 ECD_03825 cystathionine gamma-synthase, PLP-dependent low > 60
Escherichia coli ECOR27 1.00 NOLOHH_14445 alaA alanine transaminase AlaA 1.00 NOLOHH_05820 metB cystathionine gamma-synthase low > 57
Escherichia coli ECRC62 1.00 BNILDI_13365 alaA alanine transaminase AlaA 1.00 BNILDI_05715 metB cystathionine gamma-synthase — —
Escherichia coli ECRC99 1.00 KEDOAH_05370 alaA alanine transaminase AlaA 0.99 KEDOAH_14485 metB cystathionine gamma-synthase — —
Escherichia coli ECRC101 1.00 MCAODC_13865 alaA alanine transaminase AlaA 0.99 MCAODC_04175 metB cystathionine gamma-synthase — —
Escherichia coli ECRC98 1.00 JDDGAC_26790 alaA alanine transaminase AlaA 0.99 JDDGAC_17300 metB cystathionine gamma-synthase — —
Escherichia coli ECRC102 1.00 NIAGMN_20595 alaA alanine transaminase AlaA 0.99 NIAGMN_11430 metB cystathionine gamma-synthase — —
Escherichia coli ECRC101 1.00 OKFHMN_22825 alaA alanine transaminase AlaA 0.99 OKFHMN_13675 metB cystathionine gamma-synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1894 Aspartate aminotransferase (EC 2.6.1.1) 0.97 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Klebsiella michiganensis M5al 0.97 BWI76_RS20205 aminotransferase AlaT 0.96 BWI76_RS00785 cystathionine gamma-synthase 0.19 71
Enterobacter asburiae PDN3 0.97 EX28DRAFT_0319 Aspartate/tyrosine/aromatic aminotransferase 0.96 EX28DRAFT_4411 cystathionine gamma-synthase (EC 2.5.1.48) low > 76
Enterobacter sp. TBS_079 0.96 MPMX20_03220 Glutamate-pyruvate aminotransferase AlaA 0.95 MPMX20_04531 Cystathionine gamma-synthase low > 85
Pantoea sp. MT58 0.93 IAI47_06350 pyridoxal phosphate-dependent aminotransferase 0.82 IAI47_00880 cystathionine gamma-synthase low > 76
Dickeya dadantii 3937 0.93 DDA3937_RS14345 pyridoxal phosphate-dependent aminotransferase 0.86 DDA3937_RS00950 cystathionine gamma-synthase low > 74
Dickeya dianthicola ME23 0.93 DZA65_RS14995 pyridoxal phosphate-dependent aminotransferase 0.87 DZA65_RS21470 cystathionine gamma-synthase low > 75
Dickeya dianthicola 67-19 0.92 HGI48_RS14320 pyridoxal phosphate-dependent aminotransferase 0.87 HGI48_RS20425 cystathionine gamma-synthase low > 71
Pectobacterium carotovorum WPP14 0.91 HER17_RS07115 pyridoxal phosphate-dependent aminotransferase 0.87 HER17_RS00910 cystathionine gamma-synthase low > 75
Erwinia tracheiphila SCR3 0.91 LU632_RS07955 pyridoxal phosphate-dependent aminotransferase 0.87 LU632_RS19640 metB cystathionine gamma-synthase 0.91 2
Serratia liquefaciens MT49 0.91 IAI46_17720 pyridoxal phosphate-dependent aminotransferase 0.83 IAI46_24540 cystathionine gamma-synthase low > 86
Rahnella sp. WP5 0.88 EX31_RS19445 pyridoxal phosphate-dependent aminotransferase 0.78 EX31_RS14215 cystathionine gamma-synthase 0.61 27
Vibrio cholerae E7946 ATCC 55056 0.81 CSW01_09870 pyridoxal phosphate-dependent aminotransferase 0.60 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Pseudomonas sp. RS175 0.75 PFR28_00984 Glutamate-pyruvate aminotransferase AlaA 0.31 PFR28_02810 O-succinylhomoserine sulfhydrylase low > 88
Pseudomonas putida KT2440 0.75 PP_1872 glutamate-pyruvate aminotransferase 0.35 PP_4594 putative Cystathionine gamma-synthase low > 96
Pseudomonas fluorescens FW300-N2E2 0.75 Pf6N2E2_2446 Aspartate aminotransferase (EC 2.6.1.1) 0.31 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 103
Pseudomonas fluorescens GW456-L13 0.75 PfGW456L13_2252 Aspartate aminotransferase (EC 2.6.1.1) 0.31 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.38 39
Pseudomonas fluorescens FW300-N2C3 0.75 AO356_03090 aminotransferase 0.31 AO356_21470 O-succinylhomoserine sulfhydrylase 0.22 67
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_19150 aminotransferase 0.41 AO353_23295 cystathionine beta-lyase low > 101
Pseudomonas fluorescens FW300-N1B4 0.74 Pf1N1B4_261 Aspartate aminotransferase (EC 2.6.1.1) 0.40 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) low > 87
Pseudomonas sp. S08-1 0.74 OH686_22575 Alanine transaminase 0.30 OH686_04415 O-succinylhomoserine sulfhydrylase low > 80
Pseudomonas fluorescens SBW25 0.74 PFLU_RS08510 pyridoxal phosphate-dependent aminotransferase 0.39 PFLU_RS16625 cystathionine gamma-synthase low > 109
Pseudomonas simiae WCS417 0.74 PS417_08560 aminotransferase 0.34 PS417_11735 methionine gamma-lyase low > 88
Pseudomonas fluorescens SBW25-INTG 0.74 PFLU_RS08510 pyridoxal phosphate-dependent aminotransferase 0.39 PFLU_RS16625 cystathionine gamma-synthase low > 109
Pseudomonas stutzeri RCH2 0.74 Psest_1772 Aspartate/tyrosine/aromatic aminotransferase 0.32 Psest_2578 O-succinylhomoserine sulfhydrylase 0.79 4
Pseudomonas syringae pv. syringae B728a 0.73 Psyr_3615 Aminotransferase, class I and II 0.31 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.57 4
Pseudomonas syringae pv. syringae B728a ΔmexB 0.73 Psyr_3615 Aminotransferase, class I and II 0.31 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.78 11
Shewanella oneidensis MR-1 0.73 SO2483 aspartate aminotransferase, putative (NCBI ptt file) 0.59 SO4056 metB cystathionine gamma-synthase (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.73 Shew_1914 aminotransferase AlaT (RefSeq) 0.60 Shew_0520 O-succinylhomoserine (thiol)-lyase (RefSeq) 0.38 53
Shewanella amazonensis SB2B 0.73 Sama_1697 aminotransferase AlaT (RefSeq) 0.60 Sama_3171 cystathionine gamma-synthase (RefSeq) low > 62
Shewanella sp. ANA-3 0.72 Shewana3_2145 aminotransferase AlaT (RefSeq) 0.60 Shewana3_3614 cystathionine gamma-synthase (RefSeq) low > 73
Marinobacter adhaerens HP15 0.68 HP15_2095 aspartate aminotransferase 0.28 HP15_1820 methionine gamma-lyase 0.89 9
Dechlorosoma suillum PS 0.68 Dsui_2908 aspartate/tyrosine/aromatic aminotransferase 0.37 Dsui_2042 cystathionine beta-lyase/cystathionine gamma-synthase low > 51
Ralstonia solanacearum GMI1000 0.67 RS_RS06650 pyridoxal phosphate-dependent aminotransferase 0.27 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase low > 80
Ralstonia sp. UNC404CL21Col 0.67 ABZR87_RS11440 pyridoxal phosphate-dependent aminotransferase 0.29 ABZR87_RS13810 O-acetylhomoserine aminocarboxypropyltransferase low > 80
Acinetobacter radioresistens SK82 0.67 MPMX26_01871 Glutamate-pyruvate aminotransferase AlaA 0.32 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36
Cupriavidus basilensis FW507-4G11 0.67 RR42_RS12545 aminotransferase 0.28 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.42 25
Ralstonia solanacearum UW163 0.67 UW163_RS13315 pyridoxal phosphate-dependent aminotransferase 0.28 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum IBSBF1503 0.67 RALBFv3_RS15870 pyridoxal phosphate-dependent aminotransferase 0.28 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase low > 76
Ralstonia solanacearum PSI07 0.66 RPSI07_RS17495 pyridoxal phosphate-dependent aminotransferase 0.27 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase low > 81
Acidovorax sp. GW101-3H11 0.66 Ac3H11_1508 Aspartate aminotransferase (EC 2.6.1.1) 0.31 Ac3H11_34 Methionine gamma-lyase (EC 4.4.1.11) low > 79
Herbaspirillum seropedicae SmR1 0.66 HSERO_RS10455 aminotransferase 0.22 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase low > 78
Alteromonas macleodii MIT1002 0.66 MIT1002_02306 Glutamate-pyruvate aminotransferase AlaA 0.21 MIT1002_02266 Methionine gamma-lyase 0.76 44
Burkholderia phytofirmans PsJN 0.66 BPHYT_RS08950 aminotransferase 0.30 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.90 1
Variovorax sp. OAS795 0.66 ABID97_RS10885 pyridoxal phosphate-dependent aminotransferase 0.28 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Paraburkholderia sabiae LMG 24235 0.65 QEN71_RS22410 pyridoxal phosphate-dependent aminotransferase 0.30 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.65 GFF3934 Aspartate aminotransferase (EC 2.6.1.1) 0.29 GFF5245 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 90
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_00809 alanine-synthesizing transaminase 0.30 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase low > 103
Paraburkholderia graminis OAS925 0.65 ABIE53_002025 alanine-synthesizing transaminase 0.30 ABIE53_004817 O-succinylhomoserine sulfhydrylase 0.39 34
Variovorax sp. SCN45 0.65 GFF2803 Alanine transaminase (EC 2.6.1.2) 0.28 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Mycobacterium tuberculosis H37Rv 0.63 Rv0337c Probable aspartate aminotransferase AspC (transaminase A) (ASPAT) 0.38 Rv1079 Cystathionine gamma-synthase MetB (CGS) (O-succinylhomoserine [thiol]-lyase) — —
Bifidobacterium breve UCC2003 0.63 BBR_RS15560 aminotransferase class V-fold PLP-dependent enzyme 0.34 BBR_RS13145 cystathionine gamma-synthase low > 34
Pontibacter actiniarum KMM 6156, DSM 19842 0.61 CA264_06065 aminotransferase 0.41 CA264_20315 cystathionine gamma-synthase low > 74
Lysobacter sp. OAE881 0.43 ABIE51_RS18840 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.57 ABIE51_RS16185 O-succinylhomoserine (thiol)-lyase 0.53 34
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_12720 aspB aminotransferase 0.53 OKGIIK_01515 metB cystathionine gamma-synthase low > 52
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.1010.1 Aspartate aminotransferase (EC 2.6.1.1) 0.56 Xcc-8004.1596.1 hypothetical protein low > 74
Rhodanobacter denitrificans MT42 0.39 LRK55_RS10860 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.55 LRK55_RS05085 cystathionine gamma-synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS11155 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.55 LRK54_RS05305 cystathionine gamma-synthase low > 59
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS12435 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.54 ABZR86_RS19030 cystathionine gamma-synthase 0.73 52
Brevundimonas sp. GW460-12-10-14-LB2 0.20 A4249_RS04680 pyridoxal phosphate-dependent aminotransferase 0.56 A4249_RS16160 cystathionine gamma-synthase — —
Rhodopseudomonas palustris CGA009 0.19 TX73_022440 pyridoxal phosphate-dependent aminotransferase 0.32 TX73_001930 methionine gamma-lyase — —
Azospirillum sp. SherDot2 0.19 MPMX19_02392 Aspartate/prephenate aminotransferase 0.32 MPMX19_06514 L-methionine gamma-lyase low > 112
Rhizobium sp. OAE497 0.18 ABIE40_RS12925 pyridoxal phosphate-dependent aminotransferase 0.27 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase 0.89 14
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_01603 aspartate aminotransferase 0.34 CCNA_03271 methionine gamma-lyase low > 67
Caulobacter crescentus NA1000 0.18 CCNA_01603 aspartate aminotransferase 0.34 CCNA_03271 methionine gamma-lyase low > 66
Azospirillum brasilense Sp245 0.18 AZOBR_RS12970 aspartate aminotransferase 0.28 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase — —
Dinoroseobacter shibae DFL-12 0.17 Dshi_0762 aminotransferase class I and II (RefSeq) 0.28 Dshi_1002 Cystathionine gamma-synthase (RefSeq) — —
Sphingomonas koreensis DSMZ 15582 0.17 Ga0059261_2226 Aspartate/tyrosine/aromatic aminotransferase 0.27 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.90 54
Magnetospirillum magneticum AMB-1 0.17 AMB_RS02875 pyridoxal phosphate-dependent aminotransferase 0.30 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Fusobacterium nucleatum SB010 0.16 HUW76_05840 pyridoxal phosphate-dependent aminotransferase 0.34 HUW76_08240 methionine gamma-lyase low > 35

Not shown: 0 genomes with orthologs for b2290 only; 17 genomes with orthologs for b3939 only