Conservation of cofitness between b3281 and b0074 in Escherichia coli BW25113

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3281 aroE dehydroshikimate reductase, NAD(P)-binding (NCBI) 1.0 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.92 19
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00422 Shikimate dehydrogenase (NADP(+)) 1.00 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli BL21 1.00 ECD_03132 dehydroshikimate reductase, NAD(P)-binding 1.00 ECD_00076 2-isopropylmalate synthase low > 60
Escherichia coli ECOR27 0.99 NOLOHH_09355 aroE shikimate dehydrogenase 1.00 NOLOHH_03060 2-isopropylmalate synthase low > 57
Escherichia coli ECRC62 0.99 BNILDI_02165 aroE shikimate dehydrogenase 1.00 BNILDI_08550 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.98 MCAODC_08085 aroE shikimate dehydrogenase 1.00 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.98 KEDOAH_10585 aroE shikimate dehydrogenase 1.00 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECRC102 0.98 NIAGMN_15325 aroE shikimate dehydrogenase 1.00 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.98 OKFHMN_17565 aroE shikimate dehydrogenase 1.00 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli ECRC98 0.98 JDDGAC_21185 aroE shikimate dehydrogenase 1.00 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli Nissle 1917 0.97 ECOLIN_RS18840 shikimate dehydrogenase 1.00 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Escherichia coli ECOR38 0.97 HEPCGN_16385 aroE shikimate dehydrogenase 1.00 HEPCGN_08695 2-isopropylmalate synthase low > 85
Escherichia fergusonii Becca 0.96 EFB2_00542 Shikimate dehydrogenase (NADP(+)) 1.00 EFB2_03971 2-isopropylmalate synthase low > 86
Enterobacter sp. TBS_079 0.82 MPMX20_04189 Shikimate dehydrogenase (NADP(+)) 0.94 MPMX20_00769 2-isopropylmalate synthase 0.82 53
Enterobacter asburiae PDN3 0.81 EX28DRAFT_0046 shikimate dehydrogenase 0.94 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) low > 76
Klebsiella michiganensis M5al 0.81 BWI76_RS25645 shikimate dehydrogenase 0.95 BWI76_RS04680 2-isopropylmalate synthase 0.75 43
Serratia liquefaciens MT49 0.66 IAI46_23240 shikimate dehydrogenase 0.85 IAI46_03355 2-isopropylmalate synthase 0.66 20
Pantoea sp. MT58 0.66 IAI47_02315 shikimate dehydrogenase 0.84 IAI47_16000 2-isopropylmalate synthase — —
Erwinia tracheiphila SCR3 0.64 LU632_RS22445 aroE shikimate dehydrogenase 0.86 LU632_RS02880 leuA 2-isopropylmalate synthase 0.48 73
Pectobacterium carotovorum WPP14 0.62 HER17_RS02250 shikimate dehydrogenase 0.87 HER17_RS03085 2-isopropylmalate synthase 0.94 15
Rahnella sp. WP5 0.62 EX31_RS15950 shikimate dehydrogenase 0.82 EX31_RS03680 2-isopropylmalate synthase — —
Dickeya dadantii 3937 0.61 DDA3937_RS19100 shikimate dehydrogenase 0.86 DDA3937_RS18115 2-isopropylmalate synthase — —
Dickeya dianthicola 67-19 0.61 HGI48_RS19190 shikimate dehydrogenase 0.86 HGI48_RS18055 2-isopropylmalate synthase — —
Dickeya dianthicola ME23 0.60 DZA65_RS20315 shikimate dehydrogenase 0.86 DZA65_RS19200 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N1B4 0.50 Pf1N1B4_1906 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.10 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.51 45
Pseudomonas sp. RS175 0.50 PFR28_04655 Shikimate dehydrogenase (NADP(+)) 0.10 PFR28_00305 2-isopropylmalate synthase — —
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_00280 shikimate dehydrogenase 0.69 CSW01_12595 2-isopropylmalate synthase low > 62
Pseudomonas fluorescens FW300-N2C3 0.49 AO356_11315 shikimate dehydrogenase 0.11 AO356_06550 2-isopropylmalate synthase 0.45 59
Pseudomonas fluorescens FW300-N2E2 0.49 Pf6N2E2_4130 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.11 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas syringae pv. syringae B728a 0.49 Psyr_0025 shikimate dehydrogenase 0.10 Psyr_1257 2-isopropylmalate synthase 0.62 22
Pseudomonas syringae pv. syringae B728a ΔmexB 0.49 Psyr_0025 shikimate dehydrogenase 0.10 Psyr_1257 2-isopropylmalate synthase 0.66 13
Pseudomonas simiae WCS417 0.48 PS417_00125 shikimate dehydrogenase 0.10 PS417_23110 2-isopropylmalate synthase — —
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_644 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.10 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.79 18
Shewanella sp. ANA-3 0.48 Shewana3_0043 aroE shikimate 5-dehydrogenase (RefSeq) 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.91 29
Pseudomonas sp. S08-1 0.48 OH686_12485 Shikimate 5-dehydrogenase I alpha 0.12 OH686_17570 2-isopropylmalate synthase low > 80
Shewanella oneidensis MR-1 0.48 SO0040 aroE shikimate 5-dehydrogenase (NCBI ptt file) 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.88 20
Dechlorosoma suillum PS 0.48 Dsui_0443 shikimate 5-dehydrogenase 0.46 Dsui_3519 2-isopropylmalate synthase, bacterial type — —
Pseudomonas stutzeri RCH2 0.47 Psest_0029 shikimate 5-dehydrogenase 0.47 Psest_1056 2-isopropylmalate synthase, bacterial type — —
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS00120 shikimate dehydrogenase 0.10 PFLU_RS24765 2-isopropylmalate synthase — —
Pseudomonas fluorescens SBW25 0.47 PFLU_RS00120 shikimate dehydrogenase 0.10 PFLU_RS24765 2-isopropylmalate synthase — —
Shewanella loihica PV-4 0.47 Shew_3727 shikimate 5-dehydrogenase (RefSeq) 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.79 35
Pseudomonas putida KT2440 0.45 PP_0074 shikimate 5-dehydrogenase 0.10 PP_1025 2-isopropylmalate synthase — —
Shewanella amazonensis SB2B 0.43 Sama_0052 shikimate dehydrogenase (RefSeq) 0.67 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.69 46
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS27130 shikimate dehydrogenase 0.42 QEN71_RS24195 2-isopropylmalate synthase low > 153
Marinobacter adhaerens HP15 0.41 HP15_3750 shikimate dehydrogenase 0.45 HP15_538 2-isopropylmalate synthase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF5226 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.41 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Paraburkholderia graminis OAS925 0.41 ABIE53_003560 shikimate dehydrogenase 0.42 ABIE53_001580 2-isopropylmalate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.40 H281DRAFT_01679 shikimate dehydrogenase (EC 1.1.1.25) 0.42 H281DRAFT_04556 2-isopropylmalate synthase low > 103
Burkholderia phytofirmans PsJN 0.40 BPHYT_RS16975 shikimate 5-dehydrogenase 0.42 BPHYT_RS06570 2-isopropylmalate synthase low > 109
Acinetobacter radioresistens SK82 0.40 MPMX26_02748 Shikimate dehydrogenase (NADP(+)) 0.10 MPMX26_00404 2-isopropylmalate synthase low > 36
Castellaniella sp019104865 MT123 0.39 ABCV34_RS11620 shikimate dehydrogenase 0.10 ABCV34_RS12420 2-isopropylmalate synthase low > 48
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS01605 shikimate dehydrogenase 0.42 ABZR87_RS14930 2-isopropylmalate synthase low > 80
Ralstonia solanacearum IBSBF1503 0.37 RALBFv3_RS05945 shikimate dehydrogenase 0.42 RALBFv3_RS03025 2-isopropylmalate synthase low > 76
Ralstonia solanacearum UW163 0.37 UW163_RS07680 shikimate dehydrogenase 0.42 UW163_RS10700 2-isopropylmalate synthase — —
Ralstonia solanacearum GMI1000 0.37 RS_RS13890 shikimate dehydrogenase 0.42 RS_RS10395 2-isopropylmalate synthase low > 80
Ralstonia solanacearum PSI07 0.37 RPSI07_RS11300 shikimate dehydrogenase 0.42 RPSI07_RS14285 2-isopropylmalate synthase low > 81
Cupriavidus basilensis FW507-4G11 0.37 RR42_RS17645 shikimate dehydrogenase 0.42 RR42_RS05465 2-isopropylmalate synthase low > 128
Rhodanobacter denitrificans FW104-10B01 0.33 LRK54_RS08595 shikimate dehydrogenase 0.39 LRK54_RS10345 2-isopropylmalate synthase low > 59
Rhodanobacter denitrificans MT42 0.33 LRK55_RS08360 shikimate dehydrogenase 0.39 LRK55_RS09985 2-isopropylmalate synthase low > 63
Xanthomonas campestris pv. campestris strain 8004 0.33 Xcc-8004.5020.1 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.39 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.80 28
Dyella japonica UNC79MFTsu3.2 0.33 ABZR86_RS14985 shikimate dehydrogenase 0.41 ABZR86_RS15970 2-isopropylmalate synthase 0.98 1
Acidovorax sp. GW101-3H11 0.32 Ac3H11_4044 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.41 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Rhodanobacter sp. FW510-T8 0.32 OKGIIK_15365 aroE shikimate dehydrogenase 0.38 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Variovorax sp. SCN45 0.32 GFF4456 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.41 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Alteromonas macleodii MIT1002 0.31 MIT1002_00029 Shikimate dehydrogenase 0.62 MIT1002_00949 2-isopropylmalate synthase — —
Lysobacter sp. OAE881 0.31 ABIE51_RS01815 shikimate dehydrogenase 0.40 ABIE51_RS17570 2-isopropylmalate synthase 0.68 38
Variovorax sp. OAS795 0.29 ABID97_RS06300 shikimate dehydrogenase 0.41 ABID97_RS14910 2-isopropylmalate synthase — —
Dinoroseobacter shibae DFL-12 0.25 Dshi_3450 shikimate 5-dehydrogenase (RefSeq) 0.38 Dshi_0596 2-isopropylmalate synthase (RefSeq) — —
Agrobacterium fabrum C58 0.24 Atu0003 shikimate 5-dehydrogenase 0.10 Atu2264 2-isopropylmalate synthase — —
Phaeobacter inhibens DSM 17395 0.23 PGA1_c35150 shikimate dehydrogenase AroE 0.40 PGA1_c26470 2-isopropylmalate synthase LeuA — —
Sinorhizobium meliloti 1021 0.23 SMc02791 shikimate 5-dehydrogenase 0.15 SMc02546 alpha-isopropylmalate/homocitrate synthase family transferase — —
Rhodopseudomonas palustris CGA009 0.22 TX73_022410 shikimate dehydrogenase 0.42 TX73_010545 2-isopropylmalate synthase — —
Bosea sp. OAE506 0.19 ABIE41_RS04650 shikimate dehydrogenase 0.41 ABIE41_RS13000 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 Δfur 0.19 CCNA_00003 shikimate 5-dehydrogenase 0.40 CCNA_01610 2-isopropylmalate synthase low > 67
Caulobacter crescentus NA1000 0.19 CCNA_00003 shikimate dehydrogenase (EC 1.1.1.25) (from data) 0.40 CCNA_01610 2-isopropylmalate synthase low > 66
Sphingomonas koreensis DSMZ 15582 0.17 Ga0059261_2194 shikimate dehydrogenase (EC 1.1.1.25) (from data) 0.12 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.92 21
Bacteroides ovatus ATCC 8483 0.17 BACOVA_05065 putative shikimate dehydrogenase 0.42 BACOVA_04604 2-isopropylmalate synthase — —
Bacteroides stercoris CC31F 0.17 HMPREF1181_RS06320 shikimate dehydrogenase 0.42 HMPREF1181_RS14150 2-isopropylmalate synthase 0.82 20
Bacteroides thetaiotaomicron VPI-5482 0.17 BT4215 shikimate dehydrogenase (EC 1.1.1.25) (from data) 0.42 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) — —
Phocaeicola vulgatus CL09T03C04 0.16 HMPREF1058_RS16750 shikimate dehydrogenase 0.44 HMPREF1058_RS14545 2-isopropylmalate synthase low > 67
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS12665 shikimate dehydrogenase 0.44 ABI39_RS10195 2-isopropylmalate synthase 0.75 41

Not shown: 10 genomes with orthologs for b3281 only; 8 genomes with orthologs for b0074 only