| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis JJ | MMJJ_RS07240 | | MBL fold metallo-hydrolase | strong | 100 | 100 |
| o | Methanococcus maripaludis S2 | MMP_RS07115 | | MBL fold metallo-hydrolase | strong | 100 | 100 |
| | Methanococcus maripaludis S2 | MMP_RS03635 | | beta-CASP ribonuclease aCPSF1 | no data | 35 | 96 |
| | Methanococcus maripaludis JJ | MMJJ_RS01415 | | beta-CASP ribonuclease aCPSF1 | sig. | 35 | 96 |
| | Methanococcus maripaludis JJ | MMJJ_RS02985 | | MBL fold metallo-hydrolase | strong | 33 | 91 |
| | Methanococcus maripaludis S2 | MMP_RS02290 | | MBL fold metallo-hydrolase | strong | 33 | 91 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS01950 | | MBL fold metallo-hydrolase | insig. | 30 | 97 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS11070 | | MBL fold metallo-hydrolase | insig. | 29 | 97 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_05985 | | MBL fold hydrolase | insig. | 28 | 96 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS01315 | | MBL fold metallo-hydrolase RNA specificity domain-containing protein | insig. | 31 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS09610 | | mRNA 3'-end processing factor | insig. | 28 | 97 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS18635 | | MBL fold metallo-hydrolase | insig. | 33 | 92 |
| | Marinobacter adhaerens HP15 | HP15_2406 | | metallo-beta-lactamase family protein | insig. | 29 | 91 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS06000 | | MBL fold metallo-hydrolase | insig. | 28 | 98 |
| | Ralstonia solanacearum GMI1000 | RS_RS00995 | | MBL fold metallo-hydrolase | insig. | 27 | 97 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3814 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | insig. | 28 | 97 |
| | Pseudomonas putida KT2440 | PP_3291 | | Metallo-beta-lactamase family protein | insig. | 28 | 94 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3165 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | insig. | 28 | 98 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_21655 | | MBL fold hydrolase | insig. | 30 | 98 |
| | Lysobacter sp. OAE881 | ABIE51_RS06640 | | MBL fold metallo-hydrolase | insig. | 28 | 98 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_18450 | | MBL fold metallo-hydrolase | strong | 26 | 98 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0356 | | Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain | insig. | 30 | 99 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS09240 | | MBL fold metallo-hydrolase | insig. | 30 | 93 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS13890 | | MBL fold metallo-hydrolase | insig. | 29 | 93 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS14170 | | MBL fold metallo-hydrolase | insig. | 29 | 93 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS14480 | | MBL fold metallo-hydrolase | insig. | 28 | 98 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS20845 | | MBL fold hydrolase | insig. | 28 | 93 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS19990 | | MBL fold metallo-hydrolase | insig. | 27 | 97 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_00845 | ySH1 | MBL fold metallo-hydrolase | cofit | 29 | 98 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS27805 | | RNA-metabolising metallo-beta-lactamase | insig. | 29 | 96 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3226 | | Metallo-beta-lactamase family protein, RNA-specific | insig. | 28 | 94 |
| | Cellulophaga baltica 18 | M666_RS11770 | | MBL fold metallo-hydrolase | insig. | 30 | 91 |
| | Dechlorosoma suillum PS | Dsui_1635 | | putative exonuclease of the beta-lactamase fold involved in RNA processing | cofit | 28 | 93 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1530 | | metallo-beta-lactamase family protein (TIGR) | insig. | 27 | 97 |
| | Alteromonas macleodii MIT1002 | MIT1002_03270 | | Ribonuclease | insig. | 29 | 98 |
| o | Sphingobium sp. HT1-2 | GFF5006 | | Metallo-beta-lactamase family protein, RNA-specific | cofit | 27 | 97 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS13845 | | MBL fold metallo-hydrolase | insig. | 28 | 99 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS14125 | | MBL fold metallo-hydrolase | insig. | 28 | 99 |
| | Rhodopseudomonas palustris CGA009 | TX73_021505 | | MBL fold metallo-hydrolase | insig. | 28 | 93 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS14440 | | MBL fold metallo-hydrolase | insig. | 28 | 93 |
| o | Kangiella aquimarina DSM 16071 | B158DRAFT_1678 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | insig. | 29 | 88 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1519 | | Metallo-beta-lactamase family protein, RNA-specific | insig. | 26 | 91 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_23925 | | mRNA 3'-end processing factor | insig. | 26 | 91 |
| | Azospirillum brasilense Sp245 | AZOBR_RS07000 | | beta-lactamase | insig. | 27 | 96 |
| | Variovorax sp. SCN45 | GFF6952 | | Metallo-beta-lactamase family protein, RNA-specific | insig. | 28 | 96 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_1523 | | Metallo-beta-lactamase family protein, RNA-specific | insig. | 28 | 97 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_01365 | | MBL fold hydrolase | cofit | 28 | 91 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS04385 | | MBL fold metallo-hydrolase | insig. | 28 | 92 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1606 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | insig. | 28 | 92 |
| | Pseudomonas stutzeri RCH2 | Psest_2869 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | insig. | 27 | 100 |
| | Pseudomonas sp. RS175 | PFR28_02316 | | Ribonuclease | insig. | 26 | 91 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_19925 | | mRNA 3'-end processing factor | insig. | 27 | 89 |
| | Azospirillum sp. SherDot2 | MPMX19_05334 | | hypothetical protein | insig. | 26 | 96 |
| | Pseudomonas sp. BP01 | JOY50_RS16110 | | MBL fold metallo-hydrolase RNA specificity domain-containing protein | insig. | 25 | 94 |
| | Sphingobium sp. HT1-2 | GFF4359 | | Metallo-beta-lactamase family protein, RNA-specific | insig. | 26 | 91 |
| o | Caulobacter crescentus NA1000 | CCNA_00854 | | metallo-beta-lactamase protein | insig. | 28 | 92 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_00854 | | metallo-beta-lactamase protein | cofit | 28 | 92 |
| | Shewanella loihica PV-4 | Shew_3327 | | RNA-metabolising metallo-beta-lactamase (RefSeq) | insig. | 28 | 93 |
| | Sinorhizobium meliloti 1021 | SMa1131 | | Metallo-beta-lactamase superfamily protein | insig. | 27 | 91 |
| | Pseudomonas putida KT2440 | PP_1775 | | Metallo-beta-lactamase family protein | strong | 24 | 94 |
| | Marinobacter adhaerens HP15 | HP15_2380 | | metallo-beta-lactamase family protein | insig. | 27 | 91 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0171 | | beta-lactamase domain protein (RefSeq) | sig. | 26 | 97 |
| | Shewanella amazonensis SB2B | Sama_0497 | | metallo-beta-lactamase family protein (RefSeq) | insig. | 28 | 93 |
| | Shewanella sp. ANA-3 | Shewana3_0537 | | aspartate kinase (RefSeq) | insig. | 27 | 92 |
| | Shewanella oneidensis MR-1 | SO0541 | | metallo-beta-lactamase family protein (NCBI ptt file) | insig. | 27 | 92 |
| | Pseudomonas stutzeri RCH2 | Psest_1808 | | Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain | insig. | 24 | 91 |
| | Marinobacter adhaerens HP15 | HP15_1324 | | metallo-beta-lactamase family protein | insig. | 28 | 73 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3639 | | Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase | insig. | 24 | 91 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3639 | | Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase | insig. | 24 | 91 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS16630 | | MBL fold metallo-hydrolase | strong | 24 | 62 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS13225 | | exonuclease | sig. | 29 | 44 |
| | Rhodopseudomonas palustris CGA009 | TX73_004140 | | ligase-associated DNA damage response exonuclease | insig. | 24 | 50 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS14095 | | MBL fold metallo-hydrolase | insig. | 23 | 85 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3852 | | putative exonuclease, DNA ligase-associated | insig. | 23 | 54 |
| | Variovorax sp. SCN45 | GFF3696 | | mRNA 3-end processing factor | insig. | 22 | 52 |
| | Fusobacterium nucleatum SB010 | HUW76_04205 | | ribonuclease J | no data | 24 | 52 |
| | Rhizobium sp. OAE497 | ABIE40_RS04630 | | ligase-associated DNA damage response exonuclease | insig. | 24 | 54 |
| | Azospirillum sp. SherDot2 | MPMX19_02216 | | hypothetical protein | insig. | 23 | 50 |
| | Sinorhizobium meliloti 1021 | SMc03176 | | hypothetical protein | insig. | 22 | 58 |
| | Xanthobacter sp. DMC5 | GFF152 | | hypothetical protein | insig. | 24 | 50 |
| | Agrobacterium fabrum C58 | Atu0839 | | hypothetical protein | sig. | 23 | 50 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3654.1 | | hypothetical protein | insig. | 24 | 27 |
| | Azospirillum brasilense Sp245 | AZOBR_RS09955 | | beta-lactamase | insig. | 23 | 50 |
| | Sphingobium sp. HT1-2 | GFF106 | | mRNA 3-end processing factor | insig. | 25 | 36 |
| | Phaeobacter inhibens DSM 17395 | PGA1_262p00510 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | sig. | 21 | 48 |
| | Variovorax sp. OAS795 | ABID97_RS00395 | | ligase-associated DNA damage response exonuclease | insig. | 22 | 50 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS21350 | | ligase-associated DNA damage response exonuclease | insig. | 23 | 50 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20350 | | ligase-associated DNA damage response exonuclease | insig. | 25 | 42 |
| | Alteromonas macleodii MIT1002 | MIT1002_03767 | | Ribonuclease | insig. | 20 | 50 |
| | Sphingobium sp. HT1-2 | GFF4757 | | Metallo-beta-lactamase family protein, RNA-specific | no data | 35 | 17 |
| | Klebsiella michiganensis M5al | BWI76_RS07160 | | MBL fold hydrolase | insig. | 26 | 32 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1700 | | metallo-beta-lactamase family protein (TIGR) | insig. | 24 | 56 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4823 | | STY3078 protein | insig. | 41 | 15 |
| | Klebsiella michiganensis M5al | BWI76_RS15165 | | MBL fold metallo-hydrolase | insig. | 30 | 23 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02820 | | putative mRNA 3-end processing factor | insig. | 21 | 48 |
| | Pseudomonas stutzeri RCH2 | Psest_1649 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | insig. | 22 | 53 |
| | Bosea sp. OAE506 | ABIE41_RS24100 | | ligase-associated DNA damage response exonuclease | insig. | 22 | 34 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1152 | | Metallo-beta-lactamase superfamily | insig. | 25 | 36 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS09100 | | DNA ligase-associated DEXH box helicase | insig. | 23 | 48 |
| | Pseudomonas sp. RS175 | PFR28_00509 | | hypothetical protein | insig. | 22 | 55 |