| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Alteromonas macleodii MIT1002 | MIT1002_02465 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 100 | 100 |
| o | Shewanella oneidensis MR-1 | SO2366 | | response regulator (NCBI ptt file) | insig. | 42 | 100 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_15035 | | transcriptional regulator | insig. | 41 | 99 |
| o | Shewanella loihica PV-4 | Shew_1983 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 43 | 97 |
| | Shewanella sp. ANA-3 | Shewana3_2105 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 42 | 100 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0722 | | response regulator (TIGR) | insig. | 40 | 96 |
| | Shewanella amazonensis SB2B | Sama_1789 | | response regulator receiver protein (RefSeq) | insig. | 40 | 100 |
| | Alteromonas macleodii MIT1002 | MIT1002_01516 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 38 | 99 |
| | Azospirillum brasilense Sp245 | AZOBR_RS00880 | | regulator | sig. | 37 | 92 |
| o | Azospirillum sp. SherDot2 | MPMX19_05513 | | 3'3'-cGAMP-specific phosphodiesterase 2 | insig. | 37 | 95 |
| | Azospirillum sp. SherDot2 | MPMX19_00086 | | 3'3'-cGAMP-specific phosphodiesterase 2 | insig. | 35 | 95 |
| | Azospirillum sp. SherDot2 | MPMX19_02416 | | 3'3'-cGAMP-specific phosphodiesterase 2 | insig. | 26 | 92 |
| | Rhodopseudomonas palustris CGA009 | TX73_024895 | | DUF3369 domain-containing protein | insig. | 36 | 61 |
| | Azospirillum brasilense Sp245 | AZOBR_RS00185 | | transcriptional regulator | insig. | 28 | 95 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23235 | | DUF3369 domain-containing protein | insig. | 38 | 59 |
| | Azospirillum sp. SherDot2 | MPMX19_00460 | | Sensor histidine kinase RcsC | insig. | 37 | 59 |
| | Rhodospirillum rubrum S1H | Rru_A0131 | | Response regulator receiver (CheY) and unknown domain protein (NCBI) | insig. | 35 | 61 |
| | Azospirillum sp. SherDot2 | MPMX19_00959 | | Adaptive-response sensory-kinase SasA | insig. | 31 | 73 |
| | Shewanella amazonensis SB2B | Sama_0496 | | putative diguanylate phosphodiesterase (RefSeq) | insig. | 35 | 57 |
| | Shewanella amazonensis SB2B | Sama_3111 | | response regulator receiver protein (RefSeq) | insig. | 43 | 40 |
| | Shewanella sp. ANA-3 | Shewana3_3334 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 43 | 39 |
| | Azospirillum sp. SherDot2 | MPMX19_04073 | | hypothetical protein | insig. | 44 | 39 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17390 | | two-component system response regulator | insig. | 43 | 38 |
| | Dechlorosoma suillum PS | Dsui_1863 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 43 | 37 |
| | Azospirillum brasilense Sp245 | AZOBR_RS09180 | | histidine kinase | insig. | 35 | 59 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS00885 | | chemotaxis protein CheY | insig. | 41 | 40 |
| | Bosea sp. OAE506 | ABIE41_RS11550 | | HD domain-containing phosphohydrolase | insig. | 45 | 35 |
| | Azospirillum sp. SherDot2 | MPMX19_05749 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 44 | 38 |
| | Alteromonas macleodii MIT1002 | MIT1002_01768 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 42 | 41 |
| | Shewanella amazonensis SB2B | Sama_2951 | | response regulator receiver protein (RefSeq) | insig. | 45 | 38 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2418 | | Response regulator | insig. | 41 | 42 |
| | Pseudomonas sp. S08-1 | OH686_00410 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 43 | 39 |
| | Alteromonas macleodii MIT1002 | MIT1002_03376 | | Bacteriophytochrome cph2 | insig. | 35 | 58 |
| | Shewanella sp. ANA-3 | Shewana3_3418 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 44 | 38 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2900.1 | | response regulator | strong | 45 | 36 |
| | Shewanella loihica PV-4 | Shew_3199 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 44 | 38 |
| | Azospirillum sp. SherDot2 | MPMX19_05159 | | hypothetical protein | insig. | 34 | 58 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2545 | | metal dependent phosphohydrolase (RefSeq) | insig. | 40 | 39 |
| | Lysobacter sp. OAE881 | ABIE51_RS11560 | | two-component system response regulator | strong | 39 | 39 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17470 | | HD domain-containing phosphohydrolase | insig. | 36 | 44 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS17245 | | HD domain-containing protein | insig. | 36 | 44 |
| | Shewanella oneidensis MR-1 | SO0860 | | response regulator (NCBI ptt file) | insig. | 43 | 38 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3602 | | Response regulator | insig. | 40 | 42 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS06195 | | transcriptional regulator | insig. | 42 | 36 |
| | Azospirillum sp. SherDot2 | MPMX19_06045 | | putative cyclic di-GMP phosphodiesterase | insig. | 41 | 36 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3644 | | Pole remodelling regulatory diguanylate cyclase | insig. | 41 | 39 |
| | Shewanella sp. ANA-3 | Shewana3_0479 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 40 | 43 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS11770 | | HD domain-containing protein | insig. | 40 | 38 |
| | Pseudomonas sp. RS175 | PFR28_01438 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 40 | 36 |
| | Pseudomonas stutzeri RCH2 | Psest_2701 | | Response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 42 | 38 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVUA0086 | | response regulator (TIGR) | sig. | 37 | 45 |
| | Dechlorosoma suillum PS | Dsui_2782 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | no data | 39 | 37 |
| | Rhodopseudomonas palustris CGA009 | TX73_000745 | | response regulator | insig. | 39 | 42 |
| | Dechlorosoma suillum PS | Dsui_0777 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 39 | 40 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_07645 | | Phosphohydrolase | insig. | 38 | 36 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1771 | | Response regulator | insig. | 41 | 37 |
| | Pseudomonas sp. S08-1 | OH686_23605 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 38 | 41 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29820 | | phosphohydrolase | insig. | 40 | 37 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4352 | | Response regulator | insig. | 37 | 40 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06540 | | metal-dependent phosphohydrolase | insig. | 40 | 40 |
| | Azospirillum brasilense Sp245 | AZOBR_RS23460 | | divalent ion tolerance protein CutA | insig. | 39 | 39 |
| | Rhodospirillum rubrum S1H | Rru_A1908 | | Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor and Response Regulator Receiver modulation (NCBI) | insig. | 50 | 28 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01775 | | HD-GYP domain-containing protein | insig. | 41 | 37 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4541 | | Response regulator | insig. | 41 | 37 |
| | Rhodospirillum rubrum S1H | Rru_A3180 | | Metal dependent phosphohydrolase, HD region (NCBI) | insig. | 40 | 38 |
| | Shewanella oneidensis MR-1 | SO4003 | | response regulator (NCBI ptt file) | insig. | 39 | 42 |
| | Rhodospirillum rubrum S1H | Rru_A0659 | | Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation (NCBI) | insig. | 35 | 57 |
| | Azospirillum sp. SherDot2 | MPMX19_05239 | | hypothetical protein | insig. | 45 | 32 |
| | Rhodospirillum rubrum S1H | Rru_A0553 | | Response Regulator Receiver Signal Transduction Histidine Kinase (NCBI) | insig. | 52 | 28 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2270 | | Pole remodelling regulatory diguanylate cyclase | insig. | 40 | 37 |
| | Dechlorosoma suillum PS | Dsui_3000 | | putative domain HDIG-containing protein | insig. | 40 | 38 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS34710 | | chemotaxis protein CheY | insig. | 42 | 35 |
| | Azospirillum brasilense Sp245 | AZOBR_RS26775 | | hisitidine kinase | sig. | 41 | 34 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS21195 | | phosphohydrolase | insig. | 39 | 35 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2968 | | sensor histidine kinase/response regulator (TIGR) | insig. | 41 | 34 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06795 | | two-component system response regulator | insig. | 39 | 36 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2188.1 | | two-component system regulatory protein | insig. | 37 | 40 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09200 | | two-component system response regulator | cofit | 40 | 35 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09305 | | two-component system response regulator | insig. | 40 | 35 |
| | Dechlorosoma suillum PS | Dsui_2629 | | HD-GYP domain-containing protein | cofit | 42 | 37 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2310 | | Pole remodelling regulatory diguanylate cyclase | insig. | 37 | 40 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09310 | | two-component system response regulator | insig. | 39 | 36 |
| | Methylophilus sp. DMC18 | GFF1506 | | hypothetical protein | insig. | 39 | 34 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1097 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 37 | 40 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20960 | | two-component system response regulator | cofit | 36 | 40 |
| | Azospirillum sp. SherDot2 | MPMX19_01880 | | hypothetical protein | insig. | 39 | 43 |
| | Enterobacter sp. TBS_079 | MPMX20_02814 | | hypothetical protein | insig. | 39 | 36 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1407 | | metal dependent phosphohydrolase (RefSeq) | insig. | 34 | 41 |
| | Azospirillum sp. SherDot2 | MPMX19_02183 | | hypothetical protein | insig. | 47 | 27 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS12565 | | HD domain-containing protein | insig. | 37 | 40 |
| | Azospirillum sp. SherDot2 | MPMX19_05263 | | hypothetical protein | insig. | 42 | 34 |
| | Shewanella sp. ANA-3 | Shewana3_0868 | | diguanylate cyclase/phosphodiesterase (RefSeq) | insig. | 33 | 55 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14325 | | histidine kinase | cofit | 44 | 33 |
| | Shewanella loihica PV-4 | Shew_1882 | | metal dependent phosphohydrolase (RefSeq) | insig. | 38 | 39 |
| | Dechlorosoma suillum PS | Dsui_0938 | | HD-GYP domain-containing protein | insig. | 43 | 34 |
| | Variovorax sp. SCN45 | GFF1592 | | Response regulator/GGDEF/EAL domain protein | insig. | 28 | 59 |
| | Azospirillum sp. SherDot2 | MPMX19_00497 | | Sensor histidine kinase RcsC | insig. | 42 | 31 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06150 | | HD-GYP domain-containing protein | cofit | 44 | 33 |
| | Shewanella oneidensis MR-1 | SO1387 | | HD domain protein (NCBI ptt file) | insig. | 39 | 36 |
| | Dechlorosoma suillum PS | Dsui_0919 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 40 | 35 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17440 | | signal transduction histidine kinase | cofit | 44 | 31 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02865 | | response regulator | insig. | 36 | 41 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS12405 | | hypothetical protein | insig. | 45 | 27 |
| | Alteromonas macleodii MIT1002 | MIT1002_00763 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 35 | 39 |
| | Dechlorosoma suillum PS | Dsui_1228 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 41 | 36 |
| | Dechlorosoma suillum PS | Dsui_1836 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 39 | 31 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0081 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 29 | 54 |
| | Dechlorosoma suillum PS | Dsui_3001 | | putative domain HDIG-containing protein | insig. | 36 | 35 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17460 | | PAS domain S-box protein | cofit | 43 | 30 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16755 | | HD-GYP domain-containing protein | insig. | 36 | 34 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1460 | | putative PAS/PAC sensor protein (RefSeq) | cofit | 33 | 40 |
| | Rhizobium sp. OAE497 | ABIE40_RS05520 | | HD-GYP domain-containing protein | insig. | 37 | 36 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS09670 | | cyclic di-GMP phosphodiesterase | sig. | 33 | 35 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS52375 | | cyclic di-GMP phosphodiesterase | insig. | 33 | 35 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1148 | | metal dependent phosphohydrolase | insig. | 32 | 51 |
| | Shewanella loihica PV-4 | Shew_2713 | | metal dependent phosphohydrolase (RefSeq) | insig. | 36 | 36 |
| | Marinobacter adhaerens HP15 | HP15_3532 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 38 | 36 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_29680 | | cyclic di-GMP phosphodiesterase | insig. | 32 | 35 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23555 | | HD domain-containing protein | insig. | 36 | 35 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1513 | | metal dependent phosphohydrolase (RefSeq) | insig. | 37 | 34 |
| | Shewanella sp. ANA-3 | Shewana3_2820 | | metal dependent phosphohydrolase (RefSeq) | insig. | 34 | 37 |
| | Methylophilus sp. DMC18 | GFF1903 | | hypothetical protein | insig. | 35 | 36 |
| | Marinobacter adhaerens HP15 | HP15_3421 | | metal-dependent phosphohydrolase, HD subdomain protein | insig. | 41 | 31 |
| | Shewanella amazonensis SB2B | Sama_0136 | | putative metal dependent phosphohydrolase (RefSeq) | cofit | 39 | 30 |
| | Marinobacter adhaerens HP15 | HP15_4049 | | HD-GYP domain protein | insig. | 40 | 30 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2933 | | response regulator/sensory box/HDIG domain protein (TIGR) | strong | 40 | 31 |
| | Shewanella sp. ANA-3 | Shewana3_4069 | | metal dependent phosphohydrolase (RefSeq) | strong | 40 | 26 |
| | Shewanella oneidensis MR-1 | SO4711 | | HD domain protein (NCBI ptt file) | strong | 40 | 26 |
| | Marinobacter adhaerens HP15 | HP15_p187g147 | | HD-GYP domain protein | insig. | 39 | 31 |
| | Alteromonas macleodii MIT1002 | MIT1002_04107 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 38 | 32 |
| | Shewanella amazonensis SB2B | Sama_3396 | | response regulator receiver protein (RefSeq) | insig. | 32 | 40 |
| | Shewanella loihica PV-4 | Shew_2259 | | metal dependent phosphohydrolase (RefSeq) | sig. | 41 | 27 |
| | Shewanella loihica PV-4 | Shew_3670 | | metal dependent phosphohydrolase (RefSeq) | insig. | 38 | 30 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0129 | | sensory box/HDIG domain protein (TIGR) | insig. | 34 | 37 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_05340 | | HD-GYP domain-containing protein | insig. | 33 | 34 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1181 | | response regulator (TIGR) | cofit | 38 | 32 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_18790 | | metal-dependent phosphohydrolase | insig. | 34 | 33 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3123 | | HD domain protein (TIGR) | insig. | 34 | 33 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0128 | | uncharacterized domain HDIG | insig. | 38 | 30 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS12300 | | HD-GYP domain-containing protein | insig. | 35 | 33 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0130 | | uncharacterized domain HDIG | insig. | 30 | 44 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3074 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | cofit | 36 | 32 |
| | Marinobacter adhaerens HP15 | HP15_4053 | | metal-dependent phosphohydrolase, HD subdomain protein | insig. | 33 | 34 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS14075 | | HD-GYP domain-containing protein | insig. | 30 | 45 |
| | Methylophilus sp. DMC18 | GFF1539 | | Cyclic di-GMP phosphodiesterase | cofit | 37 | 30 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS03355 | | two-component system response regulator | insig. | 33 | 31 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS26120 | | HD domain-containing protein | insig. | 38 | 24 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS26120 | | HD domain-containing protein | insig. | 38 | 24 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS25540 | | phosphohydrolase | insig. | 34 | 33 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23505 | | transcriptional regulator | strong | 30 | 35 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS00610 | | HD-GYP domain-containing protein | insig. | 34 | 34 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c16320 | | putative metal dependent phosphohydrolase | insig. | 34 | 35 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0129 | | uncharacterized domain HDIG | insig. | 32 | 33 |
| | Ralstonia solanacearum GMI1000 | RS_RS12610 | | HD-GYP domain-containing protein | insig. | 34 | 33 |
| | Rhizobium sp. OAE497 | ABIE40_RS28400 | | HD-GYP domain-containing protein | insig. | 39 | 28 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0491 | | HDIG domain protein (TIGR) | insig. | 34 | 33 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS04305 | | HD domain-containing protein | cofit | 35 | 29 |
| | Dechlorosoma suillum PS | Dsui_0643 | | HD-GYP domain-containing protein | insig. | 35 | 31 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1719 | | metal dependent phosphohydrolase (RefSeq) | sig. | 33 | 33 |
| | Dechlorosoma suillum PS | Dsui_2393 | | uncharacterized domain HDIG-containing protein | cofit | 35 | 33 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS04990 | | HD-GYP domain-containing protein | insig. | 33 | 33 |
| | Ralstonia solanacearum UW163 | UW163_RS08635 | | HD-GYP domain-containing protein | insig. | 33 | 33 |
| | Pseudomonas sp. S08-1 | OH686_07455 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 31 | 36 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_17600 | | HDIG domain-containing protein | insig. | 30 | 37 |
| | Pseudomonas sp. S08-1 | OH686_14780 | | HD-GYP domain | insig. | 35 | 31 |
| | Rhizobium sp. OAE497 | ABIE40_RS13525 | | HD-GYP domain-containing protein | insig. | 39 | 28 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1338 | | metal dependent phosphohydrolase (RefSeq) | insig. | 36 | 31 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS47620 | | cyclic di-GMP phosphodiesterase | insig. | 34 | 31 |
| | Bosea sp. OAE506 | ABIE41_RS20055 | | HD domain-containing phosphohydrolase | insig. | 38 | 28 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS28015 | | cyclic di-GMP phosphodiesterase | insig. | 34 | 31 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04986 | | Cyclic di-GMP phosphodiesterase | cofit | 36 | 26 |
| | Ralstonia solanacearum GMI1000 | RS_RS02965 | | HD-GYP domain-containing protein | insig. | 35 | 29 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21160 | | cyclic di-GMP phosphodiesterase | insig. | 34 | 31 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_780 | | HDIG domain protein | insig. | 36 | 29 |
| | Pantoea sp. MT58 | IAI47_01225 | | HD-GYP domain-containing protein | insig. | 36 | 29 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS04880 | | phosphodiesterase | insig. | 42 | 26 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS19965 | | phosphodiesterase | insig. | 36 | 32 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1157 | | putative PAS/PAC sensor protein (RefSeq) | strong | 29 | 39 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29890 | | phosphodiesterase | insig. | 35 | 29 |
| | Pseudomonas segetis P6 | ACVTMO_RS19850 | | HD domain-containing phosphohydrolase | insig. | 30 | 35 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS20710 | | HD-GYP domain-containing protein | cofit | 35 | 29 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_895 | | HDIG domain protein | insig. | 35 | 31 |
| | Dechlorosoma suillum PS | Dsui_0757 | | HD-GYP domain-containing protein | insig. | 37 | 29 |
| | Pseudomonas segetis P6 | ACVTMO_RS10595 | | HD-GYP domain-containing protein | insig. | 32 | 29 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3168 | | Response regulator | insig. | 30 | 36 |
| | Agrobacterium fabrum C58 | Atu2291 | | hypothetical protein | insig. | 39 | 27 |
| | Pseudomonas segetis P6 | ACVTMO_RS00915 | | HD-GYP domain-containing protein | insig. | 37 | 31 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS21040 | | HD-GYP domain-containing protein | insig. | 34 | 29 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23735 | | phosphodiesterase | insig. | 32 | 31 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0994 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 36 | 26 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0994 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 36 | 26 |
| | Alteromonas macleodii MIT1002 | MIT1002_00945 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 36 | 27 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1796 | | uncharacterized domain HDIG | cofit | 33 | 37 |
| | Pseudomonas stutzeri RCH2 | Psest_4130 | | uncharacterized domain HDIG | insig. | 31 | 31 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18645 | | chemotaxis protein CheY | insig. | 31 | 40 |
| | Dechlorosoma suillum PS | Dsui_1886 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 27 | 43 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS13405 | | phosphodiesterase | insig. | 35 | 29 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS12275 | | HD-GYP domain-containing protein | insig. | 33 | 29 |
| | Ralstonia solanacearum UW163 | UW163_RS01330 | | HD-GYP domain-containing protein | insig. | 33 | 29 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS11195 | | phosphohydrolase | insig. | 29 | 35 |
| | Sphingobium sp. HT1-2 | GFF2515 | | hypothetical protein | cofit | 33 | 29 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.460.1 | | HDIG domain protein | insig. | 39 | 26 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS08200 | | HD-GYP domain-containing protein | sig. | 33 | 29 |
| | Pseudomonas stutzeri RCH2 | Psest_2721 | | HD-GYP domain | insig. | 36 | 31 |
| | Dechlorosoma suillum PS | Dsui_1868 | | HD-GYP domain-containing protein | insig. | 33 | 33 |
| | Pseudomonas sp. RS175 | PFR28_01424 | | Cyclic di-GMP phosphodiesterase | insig. | 34 | 29 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1785 | | HDIG domain protein | insig. | 34 | 29 |
| | Rahnella sp. WP5 | EX31_RS02155 | | HD domain-containing protein | insig. | 29 | 39 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0972 | | HD domain protein (TIGR) | insig. | 36 | 28 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1020 | | HD domain/sensory box protein (TIGR) | insig. | 30 | 37 |
| | Shewanella oneidensis MR-1 | SO3491 | | HDIG domain protein (NCBI ptt file) | insig. | 31 | 38 |
| | Dechlorosoma suillum PS | Dsui_2250 | | putative domain HDIG-containing protein | no data | 31 | 32 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_11855 | | HD-GYP domain-containing protein | insig. | 31 | 36 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08055 | | two-component system response regulator | cofit | 37 | 24 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS04735 | | phosphodiesterase | insig. | 38 | 26 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS21375 | | HD domain-containing protein | cofit | 28 | 37 |
| | Shewanella sp. ANA-3 | Shewana3_1079 | | metal dependent phosphohydrolase (RefSeq) | insig. | 33 | 31 |
| | Shewanella amazonensis SB2B | Sama_1071 | | response regulator receiver protein (RefSeq) | insig. | 27 | 41 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0666 | | HD domain protein (TIGR) | insig. | 39 | 24 |
| | Klebsiella michiganensis M5al | BWI76_RS11355 | | phosphodiesterase | insig. | 32 | 30 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2551 | | HD domain protein (TIGR) | insig. | 32 | 30 |
| | Enterobacter sp. TBS_079 | MPMX20_00946 | | 3'3'-cGAMP-specific phosphodiesterase 1 | cofit | 30 | 33 |
| | Shewanella loihica PV-4 | Shew_2351 | | metal dependent phosphohydrolase (RefSeq) | no data | 28 | 35 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS05625 | | two-component system response regulator | insig. | 27 | 35 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2662 | | metal dependent phosphohydrolase (RefSeq) | sig. | 26 | 43 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS23530 | | HD domain-containing protein | cofit | 32 | 29 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_19015 | | phosphodiesterase | insig. | 31 | 30 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0995 | | metal dependent phosphohydrolase (RefSeq) | strong | 27 | 35 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS19560 | | HD-GYP domain-containing protein | insig. | 31 | 30 |
| | Shewanella sp. ANA-3 | Shewana3_1571 | | metal dependent phosphohydrolase (RefSeq) | insig. | 30 | 28 |
| | Shewanella amazonensis SB2B | Sama_1539 | | putative metal dependent phosphohydrolase (RefSeq) | strong | 32 | 28 |
| | Alteromonas macleodii MIT1002 | MIT1002_03187 | | Chemotaxis protein CheA | insig. | 32 | 31 |
| | Shewanella oneidensis MR-1 | SO1942 | | HDIG domain protein (NCBI ptt file) | insig. | 34 | 25 |
| | Shewanella oneidensis MR-1 | SO2862 | | HDIG domain protein (NCBI ptt file) | sig. | 24 | 36 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2515 | | HD domain protein (TIGR) | strong | 32 | 26 |
| | Shewanella sp. ANA-3 | Shewana3_1721 | | metal dependent phosphohydrolase (RefSeq) | sig. | 33 | 25 |
| | Shewanella amazonensis SB2B | Sama_1519 | | putative metal dependent phosphohydrolase (RefSeq) | sig. | 30 | 31 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2661 | | metal dependent phosphohydrolase (RefSeq) | strong | 31 | 30 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02781 | | Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains | insig. | 25 | 36 |
| | Methylophilus sp. DMC18 | GFF1785 | | Cyclic di-GMP phosphodiesterase | cofit | 31 | 30 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS07430 | | LuxR family transcriptional regulator | insig. | 31 | 32 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16850 | | HD domain-containing phosphohydrolase | insig. | 23 | 37 |
| | Pseudomonas sp. S08-1 | OH686_08945 | | hypothetical protein | cofit | 28 | 34 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0966 | | metal dependent phosphohydrolase (RefSeq) | strong | 38 | 20 |
| | Shewanella loihica PV-4 | Shew_2375 | | metal dependent phosphohydrolase (RefSeq) | no data | 27 | 30 |
| | Marinobacter adhaerens HP15 | HP15_1459 | | metal dependent phosphohydrolase | insig. | 24 | 30 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12655 | | HD-GYP domain-containing protein | insig. | 30 | 24 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5467 | | Response regulator | sig. | 28 | 36 |
| | Pseudomonas sp. S08-1 | OH686_09770 | | Metal-dependent phosphohydrolase | insig. | 28 | 29 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_17715 | | chemotaxis protein CheY | insig. | 31 | 26 |