Conservation of cofitness between SMc00960 and SMc00585 in Sinorhizobium meliloti 1021

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc00960 hypothetical protein 1.0 SMc00585 leucyl aminopeptidase 0.38 5
Rhizobium sp. OAE497 0.88 ABIE40_RS04050 metalloprotease TldD 0.76 ABIE40_RS06425 leucyl aminopeptidase 0.86 46
Agrobacterium fabrum C58 0.88 Atu0765 TldD 0.69 Atu1110 cytosol aminopeptidase low > 89
Rhodopseudomonas palustris CGA009 0.69 TX73_004255 metalloprotease TldD 0.57 TX73_015830 leucyl aminopeptidase low > 86
Azospirillum sp. SherDot2 0.62 MPMX19_00882 Metalloprotease TldD 0.45 MPMX19_01593 Cytosol aminopeptidase low > 112
Azospirillum brasilense Sp245 0.62 AZOBR_RS10600 peptidase C69 0.45 AZOBR_RS16385 aminopeptidase A
Rhodospirillum rubrum S1H 0.61 Rru_A0567 Peptidase U62, modulator of DNA gyrase (NCBI) 0.49 Rru_A0454 Leucyl aminopeptidase (NCBI) low > 58
Magnetospirillum magneticum AMB-1 0.61 AMB_RS21030 metalloprotease TldD 0.47 AMB_RS18600 leucyl aminopeptidase
Caulobacter crescentus NA1000 0.60 CCNA_03522 Zn-dependent protease TldD 0.47 CCNA_01763 multifunctional aminopeptidase low > 66
Caulobacter crescentus NA1000 Δfur 0.60 CCNA_03522 Zn-dependent protease TldD 0.47 CCNA_01763 multifunctional aminopeptidase low > 67
Dinoroseobacter shibae DFL-12 0.59 Dshi_1139 peptidase U62 modulator of DNA gyrase (RefSeq) 0.41 Dshi_1191 Leucyl aminopeptidase (RefSeq) low > 64
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_2252 Predicted Zn-dependent proteases and their inactivated homologs 0.38 Ga0059261_0875 Leucyl aminopeptidase low > 68
Brevundimonas sp. GW460-12-10-14-LB2 0.57 A4249_RS10860 metalloprotease TldD 0.46 A4249_RS06730 leucyl aminopeptidase
Alteromonas macleodii MIT1002 0.52 MIT1002_00227 protease TldD 0.31 MIT1002_03197 Cytosol aminopeptidase low > 70
Pseudomonas putida KT2440 0.52 PP_0940 putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 0.34 PP_0980 Probable cytosol aminopeptidase 0.15 18
Lysobacter sp. OAE881 0.51 ABIE51_RS06795 metalloprotease TldD 0.30 ABIE51_RS04475 leucyl aminopeptidase 0.65 12
Hydrogenophaga sp. GW460-11-11-14-LB1 0.51 GFF580 TldD protein, part of TldE/TldD proteolytic complex 0.31 GFF4309 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 90
Variovorax sp. OAS795 0.51 ABID97_RS06335 metalloprotease TldD 0.31 ABID97_RS16580 leucyl aminopeptidase 0.52 27
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS01105 metalloprotease TldD 0.30 ABZR87_RS00150 leucyl aminopeptidase low > 80
Variovorax sp. SCN45 0.51 GFF4449 TldD protein, part of TldE/TldD proteolytic complex 0.31 GFF240 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 127
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.34 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 low > 86
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.34 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 low > 86
Ralstonia solanacearum PSI07 0.51 RPSI07_RS11850 metalloprotease TldD 0.31 RPSI07_RS12825 leucyl aminopeptidase low > 81
Xanthomonas campestris pv. campestris strain 8004 0.51 Xcc-8004.1883.1 TldD protein, part of TldE/TldD proteolytic complex 0.30 Xcc-8004.4446.1 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 74
Ralstonia solanacearum GMI1000 0.51 RS_RS13315 metalloprotease TldD 0.30 RS_RS12120 cytosol aminopeptidase low > 80
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS21715 metalloprotease TldD 0.29 ABZR86_RS19105 leucyl aminopeptidase low > 74
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_05215 protease TldD 0.35 AO353_04535 aminopeptidase low > 101
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS05455 metalloprotease TldD 0.30 RALBFv3_RS04550 leucyl aminopeptidase low > 76
Dechlorosoma suillum PS 0.50 Dsui_3401 putative Zn-dependent protease-like protein 0.33 Dsui_3536 leucyl aminopeptidase 0.44 36
Ralstonia solanacearum UW163 0.50 UW163_RS08170 metalloprotease TldD 0.30 UW163_RS09120 leucyl aminopeptidase
Pseudomonas fluorescens SBW25 0.50 PFLU_RS04340 metalloprotease TldD 0.35 PFLU_RS05235 leucyl aminopeptidase low > 109
Pseudomonas fluorescens SBW25-INTG 0.50 PFLU_RS04340 metalloprotease TldD 0.35 PFLU_RS05235 leucyl aminopeptidase low > 109
Pseudomonas simiae WCS417 0.50 PS417_04285 protease TldD 0.35 PS417_05165 cytosol aminopeptidase low > 88
Pseudomonas fluorescens FW300-N2E2 0.50 Pf6N2E2_3280 TldD protein, part of TldE/TldD proteolytic complex 0.35 Pf6N2E2_5420 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 103
Pseudomonas fluorescens GW456-L13 0.50 PfGW456L13_5026 TldD protein, part of TldE/TldD proteolytic complex 0.35 PfGW456L13_4846 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 87
Pseudomonas fluorescens FW300-N1B4 0.50 Pf1N1B4_1092 TldD protein, part of TldE/TldD proteolytic complex 0.34 Pf1N1B4_898 Cytosol aminopeptidase PepA (EC 3.4.11.1) 0.28 54
Pantoea sp. MT58 0.50 IAI47_02465 metalloprotease TldD 0.30 IAI47_16795 leucyl aminopeptidase 0.37 60
Pseudomonas fluorescens FW300-N2C3 0.50 AO356_07095 protease TldD 0.35 AO356_17470 aminopeptidase 0.34 25
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_02220 metalloprotease TldD 0.29 CSW01_12680 cytosol aminopeptidase low > 62
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_10280 tldD metalloprotease TldD 0.31 OKGIIK_11560 pepB leucyl aminopeptidase low > 52
Rhodanobacter denitrificans MT42 0.49 LRK55_RS03145 metalloprotease TldD 0.30 LRK55_RS12110 leucyl aminopeptidase low > 63
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS03395 metalloprotease TldD 0.30 LRK54_RS12375 leucyl aminopeptidase 0.79 40
Kangiella aquimarina DSM 16071 0.49 B158DRAFT_2072 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.33 B158DRAFT_1167 Leucyl aminopeptidase low > 40
Pseudomonas stutzeri RCH2 0.49 Psest_3320 Predicted Zn-dependent proteases and their inactivated homologs 0.34 Psest_1235 Leucyl aminopeptidase low > 67
Pseudomonas sp. RS175 0.49 PFR28_00161 Metalloprotease TldD 0.35 PFR28_03528 Cytosol aminopeptidase 0.33 19
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS03540 peptidase C69 0.33 BPHYT_RS04795 cytosol aminopeptidase low > 109
Castellaniella sp019104865 MT123 0.49 ABCV34_RS02590 metalloprotease TldD 0.31 ABCV34_RS08295 leucyl aminopeptidase
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS26555 metalloprotease TldD 0.32 QEN71_RS25205 leucyl aminopeptidase 0.78 129
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS07155 peptidase C69 0.31 HSERO_RS15600 cytosol aminopeptidase low > 78
Escherichia coli ECRC62 0.48 BNILDI_01980 tldD metalloprotease TldD 0.30 BNILDI_07455 pepA leucyl aminopeptidase
Escherichia coli Nissle 1917 0.48 ECOLIN_RS18595 metalloprotease TldD 0.30 ECOLIN_RS24695 leucyl aminopeptidase low > 52
Serratia liquefaciens MT49 0.48 IAI46_22685 metalloprotease TldD 0.30 IAI46_02360 leucyl aminopeptidase low > 86
Escherichia coli ECOR38 0.48 HEPCGN_16620 tldD metalloprotease TldD 0.30 HEPCGN_09980 pepA leucyl aminopeptidase low > 85
Escherichia fergusonii Becca 0.48 EFB2_00586 Metalloprotease TldD 0.30 EFB2_04275 Cytosol aminopeptidase low > 86
Escherichia coli BW25113 0.48 b3244 tldD predicted peptidase (NCBI) 0.30 b4260 pepA leucyl aminopeptidase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_00460 Metalloprotease TldD 0.30 OHPLBJKB_03776 Cytosol aminopeptidase low > 73
Escherichia coli BL21 0.48 ECD_03104 putative peptidase 0.30 ECD_04126 multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor low > 60
Escherichia coli ECOR27 0.48 NOLOHH_09555 tldD metalloprotease TldD 0.30 NOLOHH_04055 pepA leucyl aminopeptidase low > 57
Escherichia coli ECRC99 0.48 KEDOAH_10395 tldD metalloprotease TldD 0.30 KEDOAH_16360 pepA leucyl aminopeptidase
Escherichia coli ECRC98 0.48 JDDGAC_21380 tldD metalloprotease TldD 0.30 JDDGAC_15430 pepA leucyl aminopeptidase
Escherichia coli ECRC101 0.48 OKFHMN_17755 tldD metalloprotease TldD 0.30 OKFHMN_11790 pepA leucyl aminopeptidase
Escherichia coli ECRC101 0.48 MCAODC_08275 tldD metalloprotease TldD 0.30 MCAODC_02295 pepA leucyl aminopeptidase
Escherichia coli ECRC102 0.48 NIAGMN_15515 tldD metalloprotease TldD 0.30 NIAGMN_09640 pepA leucyl aminopeptidase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF2140 TldD protein, part of TldE/TldD proteolytic complex 0.29 GFF949 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 78
Shewanella sp. ANA-3 0.48 Shewana3_3641 microcin-processing peptidase 2 (RefSeq) 0.33 Shewana3_3324 peptidase M17, leucyl aminopeptidase domain-containing protein (RefSeq) low > 73
Pseudomonas sp. S08-1 0.48 OH686_08580 TldD protein, part of TldE/TldD proteolytic complex 0.33 OH686_07810 Cytosol aminopeptidase PepA 0.61 70
Enterobacter sp. TBS_079 0.48 MPMX20_04151 Metalloprotease TldD 0.30 MPMX20_04118 Cytosol aminopeptidase 0.31 14
Klebsiella michiganensis M5al 0.48 BWI76_RS25470 metalloprotease TldD 0.29 BWI76_RS03040 leucyl aminopeptidase low > 92
Paraburkholderia bryophila 376MFSha3.1 0.48 H281DRAFT_04688 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.33 H281DRAFT_00123 aminopeptidase A. Metallo peptidase. MEROPS family M17 low > 103
Paraburkholderia graminis OAS925 0.48 ABIE53_000851 TldD protein 0.34 ABIE53_001235 leucyl aminopeptidase 0.39 19
Shewanella loihica PV-4 0.47 Shew_0410 peptidase U62, modulator of DNA gyrase (RefSeq) 0.31 Shew_0939 leucyl aminopeptidase (RefSeq) low > 60
Erwinia tracheiphila SCR3 0.47 LU632_RS21420 tldD metalloprotease TldD 0.31 LU632_RS20855 pepA leucyl aminopeptidase low > 74
Enterobacter asburiae PDN3 0.47 EX28DRAFT_3295 Predicted Zn-dependent proteases and their inactivated homologs 0.29 EX28DRAFT_3267 Leucyl aminopeptidase low > 76
Rahnella sp. WP5 0.47 EX31_RS12265 metalloprotease TldD 0.31 EX31_RS04385 leucyl aminopeptidase low > 89
Shewanella amazonensis SB2B 0.46 Sama_0474 TldD protein (RefSeq) 0.35 Sama_0616 leucyl aminopeptidase (RefSeq) low > 62
Shewanella oneidensis MR-1 0.46 SO4091 tldD tldD protein (NCBI ptt file) 0.33 SO0959 pepA-1 cytosol aminopeptidase (NCBI ptt file) low > 76
Synechococcus elongatus PCC 7942 0.21 Synpcc7942_1127 tldD microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.25 Synpcc7942_1190 lap leucyl aminopeptidase low > 38

Not shown: 11 genomes with orthologs for SMc00960 only; 7 genomes with orthologs for SMc00585 only