Conservation of cofitness between QEN71_RS03060 and QEN71_RS05480 in Paraburkholderia sabiae LMG 24235

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Paraburkholderia sabiae LMG 24235 1.0 QEN71_RS03060 quinolinate synthase NadA 1.0 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.87 3
Burkholderia phytofirmans PsJN 0.91 BPHYT_RS15650 quinolinate synthetase 0.95 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.52 5
Paraburkholderia graminis OAS925 0.90 ABIE53_003294 quinolinate synthase 0.95 ABIE53_002857 phosphomethylpyrimidine synthase 0.38 11
Paraburkholderia bryophila 376MFSha3.1 0.90 H281DRAFT_04071 quinolinate synthetase 0.95 H281DRAFT_00395 hydroxymethylpyrimidine synthase low > 103
Ralstonia sp. UNC404CL21Col 0.76 ABZR87_RS00355 quinolinate synthase NadA 0.69 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC low > 80
Herbaspirillum seropedicae SmR1 0.76 HSERO_RS11065 quinolinate synthetase 0.86 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC low > 78
Cupriavidus basilensis FW507-4G11 0.75 RR42_RS17020 quinolinate synthetase 0.69 RR42_RS01290 thiamine biosynthesis protein ThiC low > 128
Ralstonia solanacearum GMI1000 0.75 RS_RS12295 quinolinate synthase 0.69 RS_RS00555 phosphomethylpyrimidine synthase 0.63 12
Ralstonia solanacearum PSI07 0.75 RPSI07_RS12650 quinolinate synthase NadA 0.70 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC low > 81
Ralstonia solanacearum IBSBF1503 0.75 RALBFv3_RS04735 quinolinate synthase NadA 0.69 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC low > 76
Ralstonia solanacearum UW163 0.75 UW163_RS08935 quinolinate synthase NadA 0.69 UW163_RS03640 phosphomethylpyrimidine synthase ThiC — —
Castellaniella sp019104865 MT123 0.70 ABCV34_RS03700 quinolinate synthase NadA 0.79 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC low > 48
Variovorax sp. OAS795 0.66 ABID97_RS07415 quinolinate synthase NadA 0.65 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC low > 91
Acidovorax sp. GW101-3H11 0.66 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) 0.66 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.82 14
Variovorax sp. SCN45 0.65 GFF2575 Quinolinate synthetase (EC 2.5.1.72) 0.66 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.65 GFF1216 Quinolinate synthetase (EC 2.5.1.72) 0.66 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 90
Marinobacter adhaerens HP15 0.61 HP15_2032 quinolinate synthetase complex, A subunit 0.76 HP15_453 thiamine biosynthesis protein thiC — —
Shewanella amazonensis SB2B 0.61 Sama_1712 quinolinate synthetase (RefSeq) 0.68 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) — —
Shewanella loihica PV-4 0.60 Shew_1928 quinolinate synthetase (RefSeq) 0.68 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) — —
Shewanella oneidensis MR-1 0.59 SO2342 nadA quinolinate synthetase complex, subunit A (NCBI ptt file) 0.66 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.59 Shewana3_2128 quinolinate synthetase (RefSeq) 0.66 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) — —
Pseudomonas stutzeri RCH2 0.59 Psest_1509 quinolinate synthetase complex, A subunit 0.74 Psest_0477 thiamine biosynthesis protein ThiC 0.67 2
Pectobacterium carotovorum WPP14 0.59 HER17_RS14820 quinolinate synthase NadA 0.68 HER17_RS20380 phosphomethylpyrimidine synthase ThiC low > 75
Alteromonas macleodii MIT1002 0.58 MIT1002_01344 Quinolinate synthase A 0.66 MIT1002_00097 Phosphomethylpyrimidine synthase — —
Pseudomonas putida KT2440 0.58 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit 0.76 PP_4922 Phosphomethylpyrimidine synthase 0.67 32
Serratia liquefaciens MT49 0.58 IAI46_06380 quinolinate synthase NadA 0.67 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.58 GFF4 Quinolinate synthetase (EC 2.5.1.72) 0.67 GFF4198 Thiamin biosynthesis protein ThiC — —
Enterobacter asburiae PDN3 0.58 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) 0.67 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.60 32
Escherichia coli ECRC98 0.58 JDDGAC_10415 nadA quinolinate synthase NadA 0.68 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC low > 86
Escherichia coli ECRC102 0.58 NIAGMN_04810 nadA quinolinate synthase NadA 0.68 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia fergusonii Becca 0.58 EFB2_03356 Quinolinate synthase A 0.68 EFB2_04617 Phosphomethylpyrimidine synthase low > 86
Dickeya dadantii 3937 0.58 DDA3937_RS06545 quinolinate synthase NadA 0.67 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.84 16
Acinetobacter radioresistens SK82 0.58 MPMX26_02602 Quinolinate synthase A 0.72 MPMX26_00180 Phosphomethylpyrimidine synthase low > 36
Escherichia coli ECRC101 0.58 MCAODC_25980 nadA quinolinate synthase NadA 0.68 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.94 3
Escherichia coli ECRC100 0.58 OKFHMN_06760 nadA quinolinate synthase NadA 0.68 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.94 4
Escherichia coli ECRC99 0.58 KEDOAH_21205 nadA quinolinate synthase NadA 0.68 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli Nissle 1917 0.58 ECOLIN_RS03990 quinolinate synthase NadA 0.68 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.64 9
Dickeya dianthicola 67-19 0.58 HGI48_RS06595 quinolinate synthase NadA 0.66 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.79 44
Dickeya dianthicola ME23 0.58 DZA65_RS06945 quinolinate synthase NadA 0.66 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.88 3
Pseudomonas sp. S08-1 0.58 OH686_19190 quinolinate synthetase complex, A subunit 0.74 OH686_15885 phosphomethylpyrimidine synthase 0.78 11
Escherichia coli ECOR27 0.58 NOLOHH_23190 nadA quinolinate synthase NadA 0.68 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC low > 75
Escherichia coli ECRC62 0.58 BNILDI_21185 nadA quinolinate synthase NadA 0.68 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.84 21
Enterobacter sp. TBS_079 0.58 MPMX20_01377 Quinolinate synthase A 0.68 MPMX20_00217 Phosphomethylpyrimidine synthase low > 85
Escherichia coli ECOR38 0.58 HEPCGN_01515 nadA quinolinate synthase NadA 0.67 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.88 9
Escherichia coli BL21 0.58 ECD_00703 quinolinate synthase, subunit A 0.68 ECD_03871 phosphomethylpyrimidine synthase low > 61
Escherichia coli BW25113 0.58 b0750 nadA quinolinate synthetase (NCBI) 0.68 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.64 16
Klebsiella michiganensis M5al 0.57 BWI76_RS08580 quinolinate synthetase 0.67 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.62 5
Pseudomonas simiae WCS417 0.57 PS417_22385 quinolinate synthase A 0.73 PS417_02355 thiamine biosynthesis protein ThiC low > 88
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_1542 quinolinate synthetase 0.74 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Pantoea sp. MT58 0.57 IAI47_13635 quinolinate synthase NadA 0.67 IAI47_18085 phosphomethylpyrimidine synthase ThiC low > 76
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) 0.74 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.45 12
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_1542 quinolinate synthetase 0.74 Psyr_0544 hydroxymethylpyrimidine synthase 0.75 7
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS24025 quinolinate synthase NadA 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.51 17
Pseudomonas fluorescens SBW25 0.57 PFLU_RS24025 quinolinate synthase NadA 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC low > 109
Escherichia coli HS(pFamp)R (ATCC 700891) 0.57 OHPLBJKB_02963 Quinolinate synthase A 0.68 OHPLBJKB_04056 Phosphomethylpyrimidine synthase low > 73
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) 0.74 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 103
Pseudomonas sp. RS175 0.57 PFR28_03388 Quinolinate synthase A 0.74 PFR28_05091 Phosphomethylpyrimidine synthase 0.73 3
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_18145 quinolinate synthase A 0.74 AO356_08810 thiamine biosynthesis protein ThiC 0.44 8
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) 0.74 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 87
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_03525 quinolinate synthase A 0.74 AO353_13010 thiamine biosynthesis protein ThiC 0.38 47
Rahnella sp. WP5 0.56 EX31_RS23525 quinolinate synthase NadA 0.67 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Kangiella aquimarina DSM 16071 0.56 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) 0.68 B158DRAFT_0295 hydroxymethylpyrimidine synthase — —
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_09180 quinolinate synthase 0.66 CSW01_00335 phosphomethylpyrimidine synthase low > 62
Bacteroides thetaiotaomicron VPI-5482 0.35 BT3164 quinolinate synthetase A (NCBI ptt file) 0.56 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.47 79
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS05755 quinolinate synthase NadA 0.56 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC — —
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS11230 quinolinate synthase NadA 0.56 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC — —
Bacteroides ovatus ATCC 8483 0.35 BACOVA_02839 quinolinate synthetase complex, A subunit 0.56 BACOVA_02358 thiamine biosynthesis protein ThiC 0.80 53
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS21180 quinolinate synthase 0.70 CA265_RS20165 phosphomethylpyrimidine synthase ThiC — —
Sphingomonas koreensis DSMZ 15582 0.34 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) 0.62 Ga0059261_2424 hydroxymethylpyrimidine synthase — —
Parabacteroides merdae CL09T00C40 0.34 HMPREF1078_RS06555 quinolinate synthase NadA 0.56 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS19660 quinolinate synthase NadA 0.64 AMB_RS01125 phosphomethylpyrimidine synthase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.34 ABZR88_RS20650 quinolinate synthase NadA 0.71 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC — —
Bacteroides stercoris CC31F 0.33 HMPREF1181_RS01920 quinolinate synthase NadA 0.57 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC — —
Mycobacterium tuberculosis H37Rv 0.23 Rv1594 Probable quinolinate synthetase NadA 0.51 Rv0423c Probable thiamine biosynthesis protein ThiC — —
Azospirillum brasilense Sp245 0.22 AZOBR_RS18690 quinolinate synthetase 0.64 AZOBR_RS07940 phosphomethylpyrimidine synthase low > 97
Rhodospirillum rubrum S1H 0.22 Rru_A1434 Quinolinate synthetase A (NCBI) 0.57 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) low > 58
Azospirillum sp. SherDot2 0.22 MPMX19_05670 Quinolinate synthase A 0.60 MPMX19_00336 Phosphomethylpyrimidine synthase low > 112
Agrobacterium fabrum C58 0.22 Atu4098 quinolinate synthetase 0.62 Atu2569 thiamine biosynthesis protein 0.86 5
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS00620 quinolinate synthase NadA 0.60 A4249_RS15715 phosphomethylpyrimidine synthase ThiC low > 48
Rhodanobacter sp. FW510-T8 0.21 OKGIIK_00930 nadA quinolinate synthase NadA 0.75 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC low > 52
Sinorhizobium meliloti 1021 0.21 SMc02601 quinolinate synthetase 0.63 SM_b20615 thiamine biosynthesis protein ThiC low > 103
Phaeobacter inhibens DSM 17395 0.21 PGA1_c27790 quinolinate synthetase A 0.63 PGA1_c09110 thiamine biosynthesis protein ThiC low > 62
Dechlorosoma suillum PS 0.17 Dsui_1043 quinolinate synthetase complex, A subunit 0.85 Dsui_0422 thiamine biosynthesis protein ThiC — —

Not shown: 9 genomes with orthologs for QEN71_RS03060 only; 11 genomes with orthologs for QEN71_RS05480 only