Conservation of cofitness between PP_4782 and PP_0362 in Pseudomonas putida KT2440

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4782 Phosphomethylpyrimidine kinase 1.0 PP_0362 Biotin synthase 0.57 10
Pseudomonas fluorescens SBW25 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.93 PFLU_RS27650 biotin synthase BioB low > 109
Pseudomonas fluorescens SBW25-INTG 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.93 PFLU_RS27650 biotin synthase BioB 0.31 64
Pseudomonas fluorescens FW300-N2C3 0.88 AO356_15435 hydrogenase 0.94 AO356_14135 biotin synthase 0.37 5
Pseudomonas simiae WCS417 0.87 PS417_24600 hydrogenase 0.93 PS417_26005 biotin synthase low > 88
Pseudomonas fluorescens FW300-N2E3 0.87 AO353_06350 hydrogenase 0.94 AO353_07525 biotin synthase low > 101
Pseudomonas fluorescens GW456-L13 0.87 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.93 PfGW456L13_1147 Biotin synthase (EC 2.8.1.6) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.94 Psyr_4687 biotin synthase 0.68 6
Pseudomonas syringae pv. syringae B728a 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.94 Psyr_4687 biotin synthase 0.73 6
Pseudomonas sp. RS175 0.84 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.94 PFR28_04103 Biotin synthase 0.32 79
Pseudomonas sp. S08-1 0.82 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD 0.93 OH686_10355 biotin synthase low > 80
Pseudomonas fluorescens FW300-N2E2 0.78 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.94 Pf6N2E2_4759 Biotin synthase (EC 2.8.1.6) low > 103
Pseudomonas fluorescens FW300-N1B4 0.78 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.94 Pf1N1B4_2487 Biotin synthase (EC 2.8.1.6) low > 87
Pseudomonas stutzeri RCH2 0.78 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.92 Psest_0411 biotin synthetase 0.40 8
Dechlorosoma suillum PS 0.40 Dsui_0662 phosphomethylpyrimidine kinase 0.53 Dsui_1297 biotin synthetase — —
Acinetobacter radioresistens SK82 0.38 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.59 MPMX26_01785 Biotin synthase — —
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS02135 phosphomethylpyrimidine kinase 0.51 HSERO_RS12235 biotin synthase low > 78
Rhizobium sp. OAE497 0.27 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.55 ABIE40_RS21075 biotin synthase BioB low > 107
Phocaeicola vulgatus CL09T03C04 0.27 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.23 HMPREF1058_RS17950 biotin synthase BioB low > 67
Marinobacter adhaerens HP15 0.27 HP15_349 phosphomethylpyrimidine kinase 0.70 HP15_2486 biotin synthase — —
Ralstonia solanacearum UW163 0.26 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.60 UW163_RS03115 biotin synthase BioB — —
Ralstonia solanacearum IBSBF1503 0.26 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.60 RALBFv3_RS10465 biotin synthase BioB — —
Ralstonia solanacearum PSI07 0.26 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.61 RPSI07_RS22850 biotin synthase BioB — —
Ralstonia solanacearum GMI1000 0.26 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.61 RS_RS01305 biotin synthase — —
Parabacteroides merdae CL09T00C40 0.26 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 HMPREF1078_RS15300 biotin synthase BioB low > 61
Pectobacterium carotovorum WPP14 0.25 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.67 HER17_RS13460 biotin synthase BioB low > 75
Agrobacterium fabrum C58 0.25 Atu3290 phosphomethylpyrimidine kinase 0.57 Atu3997 biotin synthetase 0.87 3
Serratia liquefaciens MT49 0.24 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 IAI46_06525 biotin synthase BioB low > 86
Hydrogenophaga sp. GW460-11-11-14-LB1 0.24 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.56 GFF3992 Biotin synthase (EC 2.8.1.6) low > 90
Ralstonia sp. UNC404CL21Col 0.24 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.61 ABZR87_RS06265 biotin synthase BioB — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.24 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.47 ABZR88_RS10190 biotin synthase BioB low > 71
Klebsiella michiganensis M5al 0.24 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 BWI76_RS08760 biotin synthase 0.16 51
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_0215 phosphomethylpyrimidine kinase 0.52 Echvi_2566 biotin synthetase low > 79
Escherichia coli BL21 0.24 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.68 ECD_00742 biotin synthase low > 60
Escherichia coli ECRC99 0.24 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 KEDOAH_21510 bioB biotin synthase BioB — —
Enterobacter sp. TBS_079 0.24 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.67 MPMX20_01403 Biotin synthase 0.40 23
Escherichia coli ECRC102 0.24 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 NIAGMN_04445 bioB biotin synthase BioB — —
Escherichia coli ECRC98 0.24 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 JDDGAC_10035 bioB biotin synthase BioB — —
Escherichia coli BW25113 0.24 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.68 b0775 bioB biotin synthase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.68 OHPLBJKB_02938 Biotin synthase low > 73
Escherichia coli ECRC101 0.24 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 OKFHMN_06400 bioB biotin synthase BioB — —
Escherichia coli ECRC101 0.24 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 MCAODC_25615 bioB biotin synthase BioB — —
Escherichia coli ECOR27 0.24 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 NOLOHH_22770 bioB biotin synthase BioB low > 57
Escherichia coli ECRC62 0.24 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 BNILDI_21040 bioB biotin synthase BioB — —
Escherichia coli ECOR38 0.23 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 HEPCGN_01640 bioB biotin synthase BioB low > 85
Lysobacter sp. OAE881 0.23 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.61 ABIE51_RS01140 biotin synthase BioB — —
Escherichia fergusonii Becca 0.23 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.68 EFB2_03330 Biotin synthase low > 86
Escherichia coli Nissle 1917 0.23 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 ECOLIN_RS04130 biotin synthase BioB — —
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 ABZR86_RS15840 biotin synthase BioB — —
Xanthomonas campestris pv. campestris strain 8004 0.23 Xcc-8004.3091.1 hypothetical protein 0.58 Xcc-8004.505.1 Biotin synthase (EC 2.8.1.6) low > 74
Rahnella sp. WP5 0.23 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 EX31_RS23695 biotin synthase BioB 0.58 3
Caulobacter crescentus NA1000 Δfur 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.55 CCNA_03636 biotin synthase — —
Caulobacter crescentus NA1000 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.55 CCNA_03636 biotin synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.67 GFF671 Biotin synthase (EC 2.8.1.6) low > 78
Erwinia tracheiphila SCR3 0.23 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.68 LU632_RS09130 bioB biotin synthase BioB — —
Dickeya dadantii 3937 0.23 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.67 DDA3937_RS08510 biotin synthase BioB 0.72 22
Fusobacterium nucleatum SB010 0.22 HUW76_10300 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.24 HUW76_05115 biotin synthase BioB low > 35
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.69 CSW01_05645 biotin synthase low > 62
Enterobacter asburiae PDN3 0.22 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.66 EX28DRAFT_2216 biotin synthase (EC 2.8.1.6) low > 76
Rhodopseudomonas palustris CGA009 0.22 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.55 TX73_010535 biotin synthase BioB — —
Paraburkholderia graminis OAS925 0.22 ABIE53_001125 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.58 ABIE53_000577 biotin synthase low > 113
Castellaniella sp019104865 MT123 0.22 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 ABCV34_RS15280 biotin synthase BioB — —
Dickeya dianthicola 67-19 0.22 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.66 HGI48_RS08675 biotin synthase BioB 0.73 51
Rhodanobacter sp. FW510-T8 0.22 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.56 OKGIIK_13650 bioB biotin synthase BioB low > 52
Dickeya dianthicola ME23 0.22 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.67 DZA65_RS08965 biotin synthase BioB 0.69 49
Paraburkholderia bryophila 376MFSha3.1 0.22 H281DRAFT_04811 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.58 H281DRAFT_02097 biotin synthase low > 103
Magnetospirillum magneticum AMB-1 0.22 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.59 AMB_RS13865 biotin synthase — —
Acidovorax sp. GW101-3H11 0.21 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.53 Ac3H11_2272 Biotin synthase (EC 2.8.1.6) — —
Sphingomonas koreensis DSMZ 15582 0.21 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 Ga0059261_3989 biotin synthase (EC 2.8.1.6) — —
Desulfovibrio vulgaris Hildenborough JW710 0.21 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) 0.23 DVU2558 bioB biotin synthase (Dmitry Rodionov) — —
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) 0.21 DvMF_1001 biotin synthase (RefSeq) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.48 CA264_02425 biotin synthase BioB low > 74
Pantoea sp. MT58 0.20 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.67 IAI47_13530 biotin synthase BioB low > 76
Paraburkholderia sabiae LMG 24235 0.19 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.59 QEN71_RS01085 biotin synthase BioB — —
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS04205 kinase 0.58 BPHYT_RS02150 biotin synthase low > 109
Pedobacter sp. GW460-11-11-14-LB5 0.19 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.47 CA265_RS09475 biotin synthase BioB low > 88
Variovorax sp. OAS795 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 ABID97_RS13955 biotin synthase BioB — —
Cupriavidus basilensis FW507-4G11 0.19 RR42_RS01370 phosphomethylpyrimidine kinase 0.58 RR42_RS00940 biotin synthase — —
Mycobacterium tuberculosis H37Rv 0.18 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.26 Rv1589 Probable biotin synthetase BioB — —
Synechococcus elongatus PCC 7942 0.17 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase 0.51 Synpcc7942_0419 bioB biotin synthase — —
Phaeobacter inhibens DSM 17395 0.17 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.54 PGA1_c09120 biotin synthase BioB low > 62
Variovorax sp. SCN45 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 GFF937 Biotin synthase (EC 2.8.1.6) low > 127

Not shown: 12 genomes with orthologs for PP_4782 only; 10 genomes with orthologs for PP_0362 only