Conservation of cofitness between GFF4198 and GFF828 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.0 GFF4198 Thiamin biosynthesis protein ThiC 1.0 GFF828 HflC protein 0.33 15
Enterobacter asburiae PDN3 0.96 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.85 EX28DRAFT_3372 HflC protein low > 76
Enterobacter sp. TBS_079 0.96 MPMX20_00217 Phosphomethylpyrimidine synthase 0.88 MPMX20_00456 Modulator of FtsH protease HflC low > 85
Escherichia fergusonii Becca 0.95 EFB2_04617 Phosphomethylpyrimidine synthase 0.90 EFB2_04360 Modulator of FtsH protease HflC low > 86
Escherichia coli Nissle 1917 0.95 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.90 ECOLIN_RS24245 protease modulator HflC
Escherichia coli ECRC99 0.95 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.90 KEDOAH_15915 hflC protease modulator HflC
Escherichia coli ECRC100 0.95 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.90 OKFHMN_12240 hflC protease modulator HflC low > 80
Escherichia coli ECRC98 0.95 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.90 JDDGAC_15880 hflC protease modulator HflC low > 86
Escherichia coli BL21 0.95 ECD_03871 phosphomethylpyrimidine synthase 0.90 ECD_04042 HflB protease modulator specific for phage lambda cII repressor low > 61
Escherichia coli ECRC102 0.95 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.90 NIAGMN_10090 hflC protease modulator HflC
Escherichia coli ECRC101 0.95 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.90 MCAODC_02755 hflC protease modulator HflC low > 87
Escherichia coli ECRC62 0.94 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.90 BNILDI_06985 hflC protease modulator HflC low > 75
Escherichia coli BW25113 0.94 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.90 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.90 OHPLBJKB_03867 Modulator of FtsH protease HflC low > 73
Escherichia coli ECOR38 0.94 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.90 HEPCGN_10470 hflC protease modulator HflC low > 87
Escherichia coli ECOR27 0.94 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.90 NOLOHH_04505 hflC protease modulator HflC low > 75
Klebsiella michiganensis M5al 0.93 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.89 BWI76_RS02550 protease modulator HflC low > 92
Pectobacterium carotovorum WPP14 0.87 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.79 HER17_RS02600 protease modulator HflC low > 75
Rahnella sp. WP5 0.86 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.80 EX31_RS08805 protease modulator HflC low > 89
Dickeya dianthicola ME23 0.85 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.75 DZA65_RS19665 protease modulator HflC low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.75 DDA3937_RS18595 protease modulator HflC
Pantoea sp. MT58 0.84 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.82 IAI47_02605 protease modulator HflC low > 76
Serratia liquefaciens MT49 0.84 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.80 IAI46_01640 protease modulator HflC low > 86
Dickeya dianthicola 67-19 0.84 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.75 HGI48_RS18530 protease modulator HflC low > 71
Erwinia tracheiphila SCR3 0.83 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.83 LU632_RS02070 hflC protease modulator HflC low > 74
Shewanella loihica PV-4 0.77 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.47 Shew_0569 HflC protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.76 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.46 Sama_3022 hflC protein (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.76 MIT1002_00097 Phosphomethylpyrimidine synthase 0.49 MIT1002_03785 Modulator of FtsH protease HflC low > 70
Shewanella oneidensis MR-1 0.74 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.48 SO0606 hflC hflC protein (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_00335 phosphomethylpyrimidine synthase 0.51 CSW01_01850 protease modulator HflC low > 62
Shewanella sp. ANA-3 0.74 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.49 Shewana3_0600 HflC protein (RefSeq) low > 73
Pseudomonas sp. RS175 0.72 PFR28_05091 Phosphomethylpyrimidine synthase 0.29 PFR28_05124 Modulator of FtsH protease HflC low > 88
Pseudomonas putida KT2440 0.71 PP_4922 Phosphomethylpyrimidine synthase 0.30 PP_4891 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex low > 96
Pseudomonas fluorescens FW300-N1B4 0.71 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.32 Pf1N1B4_1409 HflC protein
Pseudomonas fluorescens FW300-N2E2 0.71 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.31 Pf6N2E2_3611 HflC protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.71 AO356_08810 thiamine biosynthesis protein ThiC 0.31 AO356_08640 membrane protease HflC low > 104
Pseudomonas fluorescens GW456-L13 0.71 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.31 PfGW456L13_151 HflC protein low > 87
Pseudomonas syringae pv. syringae B728a 0.71 Psyr_0544 hydroxymethylpyrimidine synthase 0.31 Psyr_0575 protease FtsH subunit HflC low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.71 Psyr_0544 hydroxymethylpyrimidine synthase 0.31 Psyr_0575 protease FtsH subunit HflC low > 86
Pseudomonas stutzeri RCH2 0.71 Psest_0477 thiamine biosynthesis protein ThiC 0.30 Psest_0686 Membrane protease subunits, stomatin/prohibitin homologs
Pseudomonas sp. S08-1 0.71 OH686_15885 phosphomethylpyrimidine synthase 0.29 OH686_09455 HflC protein low > 80
Pseudomonas fluorescens FW300-N2E3 0.71 AO353_13010 thiamine biosynthesis protein ThiC 0.31 AO353_13160 membrane protease HflC low > 101
Marinobacter adhaerens HP15 0.71 HP15_453 thiamine biosynthesis protein thiC 0.31 HP15_2496 HflC low > 73
Pseudomonas simiae WCS417 0.71 PS417_02355 thiamine biosynthesis protein ThiC 0.28 PS417_02505 membane protease HflC
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.30 PFLU_RS02585 protease modulator HflC low > 109
Pseudomonas fluorescens SBW25 0.71 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.30 PFLU_RS02585 protease modulator HflC low > 109
Echinicola vietnamensis KMM 6221, DSM 17526 0.70 Echvi_3567 thiamine biosynthesis protein ThiC 0.20 Echvi_2032 HflC protein low > 79
Herbaspirillum seropedicae SmR1 0.70 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.28 HSERO_RS14760 membrane protein low > 78
Dechlorosoma suillum PS 0.69 Dsui_0422 thiamine biosynthesis protein ThiC 0.33 Dsui_3134 membrane protease subunit, stomatin/prohibitin
Dyella japonica UNC79MFTsu3.2 0.69 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.30 ABZR86_RS08350 protease modulator HflC low > 74
Burkholderia phytofirmans PsJN 0.69 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.19 BPHYT_RS12540 membrane protein
Rhodanobacter sp. FW510-T8 0.69 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.33 OKGIIK_06645 hflC protease modulator HflC low > 52
Paraburkholderia bryophila 376MFSha3.1 0.68 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.22 H281DRAFT_00524 protease FtsH subunit HflC
Paraburkholderia sabiae LMG 24235 0.68 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.21 QEN71_RS06015 protease modulator HflC low > 153
Paraburkholderia graminis OAS925 0.68 ABIE53_002857 phosphomethylpyrimidine synthase 0.24 ABIE53_002734 membrane protease subunit HflC low > 113
Castellaniella sp019104865 MT123 0.68 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.26 ABCV34_RS02665 protease modulator HflC
Lysobacter sp. OAE881 0.68 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.30 ABIE51_RS06555 protease modulator HflC low > 62
Ralstonia sp. UNC404CL21Col 0.68 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.28 ABZR87_RS10955 protease modulator HflC low > 80
Ralstonia solanacearum PSI07 0.68 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.30 RPSI07_RS18060 protease modulator HflC low > 81
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.35 B158DRAFT_1955 HflC protein low > 40
Xanthomonas campestris pv. campestris strain 8004 0.67 Xcc-8004.1066.1 hypothetical protein 0.29 Xcc-8004.3954.1 HflC protein low > 74
Ralstonia solanacearum GMI1000 0.67 RS_RS00555 phosphomethylpyrimidine synthase 0.30 RS_RS06125 protease modulator HflC
Ralstonia solanacearum UW163 0.67 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.30 UW163_RS12780 protease modulator HflC
Ralstonia solanacearum IBSBF1503 0.67 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.30 RALBFv3_RS15315 protease modulator HflC
Cupriavidus basilensis FW507-4G11 0.67 RR42_RS01290 thiamine biosynthesis protein ThiC 0.29 RR42_RS13100 membrane protein
Magnetospirillum magneticum AMB-1 0.65 AMB_RS01125 phosphomethylpyrimidine synthase 0.28 AMB_RS17655 protease modulator HflC
Azospirillum brasilense Sp245 0.65 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.26 AZOBR_RS06525 membrane protein low > 97
Phaeobacter inhibens DSM 17395 0.65 PGA1_c09110 thiamine biosynthesis protein ThiC 0.29 PGA1_c23700 protein HflC low > 62
Dinoroseobacter shibae DFL-12 0.64 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.28 Dshi_2735 HflC protein (RefSeq)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.64 GFF166 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.20 GFF4855 HflC protein low > 90
Sinorhizobium meliloti 1021 0.64 SM_b20615 thiamine biosynthesis protein ThiC 0.23 SMc01440 hydrolase serine protease transmembrane protein low > 103
Acidovorax sp. GW101-3H11 0.64 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.25 Ac3H11_1802 HflC protein low > 79
Variovorax sp. SCN45 0.64 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.24 GFF1003 HflC protein 0.62 63
Agrobacterium fabrum C58 0.63 Atu2569 thiamine biosynthesis protein 0.26 Atu2044 HFLC protein low > 89
Variovorax sp. OAS795 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.24 ABID97_RS14265 protease modulator HflC low > 91
Azospirillum sp. SherDot2 0.63 MPMX19_00336 Phosphomethylpyrimidine synthase 0.29 MPMX19_01250 Modulator of FtsH protease HflC
Sphingomonas koreensis DSMZ 15582 0.62 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.14 Ga0059261_1381 Membrane protease subunits, stomatin/prohibitin homologs low > 68
Rhodopseudomonas palustris CGA009 0.61 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.28 TX73_018075 protease modulator HflC low > 86
Bosea sp. OAE506 0.60 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.27 ABIE41_RS12855 protease modulator HflC low > 77
Rhodospirillum rubrum S1H 0.58 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.27 Rru_A2202 HflC (NCBI)

Not shown: 14 genomes with orthologs for GFF4198 only; 5 genomes with orthologs for GFF828 only