Conservation of cofitness between GFF66 and GFF2628 in Sphingobium sp. HT1-2

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF66 Cobyric acid synthase (EC 6.3.5.10) 1.0 GFF2628 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.84 2
Sphingomonas koreensis DSMZ 15582 0.72 Ga0059261_0630 adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) 0.74 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit low > 68
Azospirillum brasilense Sp245 0.62 AZOBR_RS09845 cobyric acid synthase 0.52 AZOBR_RS14135 isopropylmalate isomerase low > 97
Azospirillum sp. SherDot2 0.59 MPMX19_01025 Cobyric acid synthase 0.53 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 — —
Caulobacter crescentus NA1000 Δfur 0.57 CCNA_02776 cobyric acid synthase CobQ 0.45 CCNA_00195 3-isopropylmalate dehydratase small subunit low > 67
Caulobacter crescentus NA1000 0.57 CCNA_02776 cobyric acid synthase CobQ 0.45 CCNA_00195 3-isopropylmalate dehydratase small subunit low > 66
Sinorhizobium meliloti 1021 0.55 SMc04309 cobyric acid synthase 0.48 SMc03795 isopropylmalate isomerase small subunit — —
Rhizobium sp. OAE497 0.55 ABIE40_RS11175 cobyric acid synthase 0.47 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.94 9
Agrobacterium fabrum C58 0.54 Atu2808 cobyric acid synthase 0.49 Atu2790 3-isopropylmalate dehydratase, small subunit low > 89
Bosea sp. OAE506 0.53 ABIE41_RS03845 cobyric acid synthase 0.47 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit — —
Rhodopseudomonas palustris CGA009 0.53 TX73_003715 cobyric acid synthase 0.49 TX73_001215 3-isopropylmalate dehydratase small subunit — —
Rhodospirillum rubrum S1H 0.53 Rru_A3381 Cobyric acid synthase CobQ (NCBI) 0.48 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) low > 58
Xanthobacter sp. DMC5 0.52 GFF372 Cobyric acid synthase 0.47 GFF1843 3-isopropylmalate dehydratase small subunit 1 — —
Magnetospirillum magneticum AMB-1 0.51 AMB_RS01485 cobyric acid synthase 0.52 AMB_RS20565 3-isopropylmalate dehydratase small subunit — —
Phaeobacter inhibens DSM 17395 0.51 PGA1_c24000 cobyric acid synthase CobQ 0.50 PGA1_c29790 3-isopropylmalate dehydratase small subunit — —
Dinoroseobacter shibae DFL-12 0.50 Dshi_2096 cobyric acid synthase CobQ (RefSeq) 0.51 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) — —
Pseudomonas putida KT2440 0.45 PP_1677 Adenosyl-cobyric acid synthase 0.45 PP_1986 3-isopropylmalate dehydratase small subunit 0.38 42
Pseudomonas sp. BP01 0.45 JOY50_RS27965 cobyric acid synthase 0.45 JOY50_RS16625 leuD 3-isopropylmalate dehydratase small subunit 0.95 11
Methylophilus sp. DMC18 0.45 GFF1471 Cobyric acid synthase 0.47 GFF647 3-isopropylmalate dehydratase small subunit 1 — —
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS00040 cobyric acid synthase 0.43 ABZR87_RS14535 3-isopropylmalate dehydratase small subunit low > 80
Ralstonia solanacearum GMI1000 0.44 RS_RS12000 cobyric acid synthase 0.43 RS_RS09995 3-isopropylmalate dehydratase small subunit — —
Paraburkholderia graminis OAS925 0.44 ABIE53_001255 adenosylcobyric acid synthase 0.43 ABIE53_004803 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit 0.33 73
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_00146 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.43 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit low > 103
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS04445 cobyric acid synthase 0.42 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit low > 76
Ralstonia solanacearum UW163 0.44 UW163_RS09225 cobyric acid synthase 0.42 UW163_RS11110 3-isopropylmalate dehydratase small subunit — —
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS04900 cobyric acid synthase 0.43 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.33 74
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS25095 cobyric acid synthase 0.44 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.38 49
Ralstonia solanacearum PSI07 0.43 RPSI07_RS12925 cobyric acid synthase 0.42 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit — —
Pseudomonas aeruginosa PA14 0.43 IKLFDK_06055 cobyric acid synthase 0.45 IKLFDK_15875 3-isopropylmalate dehydratase small subunit low > 100
Pseudomonas stutzeri RCH2 0.43 Psest_3008 cobyric acid synthase CobQ 0.46 Psest_2590 3-isopropylmalate dehydratase, small subunit low > 67
Pseudomonas segetis P6 0.43 MPMX49_01822 Cobyric acid synthase 0.45 MPMX49_03073 3-isopropylmalate dehydratase small subunit 1 low > 75
Pseudomonas sp. DMC3 0.43 GFF2552 Cobyric acid synthase 0.44 GFF786 3-isopropylmalate dehydratase small subunit 1 low > 89
Pseudomonas sp. SVBP6 0.43 COO64_RS07225 cobyric acid synthase 0.46 COO64_RS05660 leuD 3-isopropylmalate dehydratase small subunit low > 93
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_5742 Cobyric acid synthase (EC 6.3.5.10) 0.44 Pf6N2E2_64 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 103
Pseudomonas sp. S08-1 0.42 OH686_04965 cobyric acid synthase CobQ 0.45 OH686_04475 3-isopropylmalate dehydratase small subunit low > 80
Shewanella sp. ANA-3 0.42 Shewana3_3275 cobyric acid synthase (RefSeq) 0.35 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) low > 73
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_19160 cobyric acid synthase 0.43 AO356_21405 3-isopropylmalate dehydratase 0.45 39
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS16075 cobyric acid synthase 0.44 RR42_RS24180 3-isopropylmalate dehydratase low > 128
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4238 Cobyric acid synthase (EC 6.3.5.10) 0.45 PfGW456L13_3947 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.44 Psyr_1984 3-isopropylmalate dehydratase, small subunit low > 86
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.44 Psyr_1984 3-isopropylmalate dehydratase, small subunit low > 86
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_02615 cobyric acid synthase 0.44 AO353_20625 3-isopropylmalate dehydratase 0.39 40
Vibrio cholerae E7946 ATCC 55056 0.42 CSW01_17810 cobyric acid synthase CobQ 0.40 CSW01_12610 3-isopropylmalate dehydratase small subunit low > 62
Dechlorosoma suillum PS 0.41 Dsui_0542 cobyric acid synthase CobQ 0.45 Dsui_3199 3-isopropylmalate dehydratase, small subunit — —
Shewanella loihica PV-4 0.41 Shew_0717 cobyric acid synthase (RefSeq) 0.38 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.77 32
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3711 Cobyric acid synthase (EC 6.3.5.10) 0.44 Pf1N1B4_14 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) — —
Pseudomonas simiae WCS417 0.41 PS417_20040 cobyric acid synthase 0.44 PS417_18595 3-isopropylmalate dehydratase 0.25 68
Pseudomonas fluorescens SBW25 0.41 PFLU_RS22005 cobyric acid synthase 0.43 PFLU_RS20575 3-isopropylmalate dehydratase small subunit low > 109
Pseudomonas lactucae CFBP13502 0.41 GEMAOFIL_04205 Cobyric acid synthase 0.43 GEMAOFIL_02265 3-isopropylmalate dehydratase small subunit 1 low > 93
Lysobacter sp. OAE881 0.41 ABIE51_RS04965 cobyric acid synthase 0.38 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit low > 62
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS22005 cobyric acid synthase 0.43 PFLU_RS20575 3-isopropylmalate dehydratase small subunit low > 109
Shewanella oneidensis MR-1 0.41 SO1038 cobQ cobyric acid synthase CobQ (NCBI ptt file) 0.35 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.69 32
Rhodanobacter sp. FW510-T8 0.41 OKGIIK_05500 cobyric acid synthase 0.36 OKGIIK_13590 leuD 3-isopropylmalate dehydratase small subunit low > 53
Pseudomonas sp. RS175 0.41 PFR28_03204 Cobyric acid synthase 0.45 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 low > 88
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS13230 cobyric acid synthase 0.44 HSERO_RS16505 3-isopropylmalate dehydratase small subunit low > 78
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS10900 cobyric acid synthase 0.36 ABZR86_RS15955 3-isopropylmalate dehydratase small subunit low > 74
Shewanella amazonensis SB2B 0.39 Sama_0765 cobyric acid synthase (RefSeq) 0.36 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) low > 62
Mycobacterium tuberculosis H37Rv 0.38 Rv0255c Probable cobyric acid synthase CobQ1 0.33 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) — —
Klebsiella michiganensis M5al 0.38 BWI76_RS23010 cobyric acid synthase CobQ 0.43 BWI76_RS04665 3-isopropylmalate dehydratase small subunit low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.37 GFF3966 Cobyric acid synthase (EC 6.3.5.10) 0.43 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 78
Klebsiella pneumoniae MKP103 0.37 KDGMDA_03575 cobyric acid synthase 0.42 KDGMDA_12895 3-isopropylmalate dehydratase small subunit low > 95
Synechocystis sp000284455 PCC 6803 0.34 SGL_RS15620 cobyric acid synthase CobQ 0.27 SGL_RS10800 3-isopropylmalate dehydratase small subunit — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS01395 cobyric acid synthase 0.32 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit low > 67
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS15660 cobyric acid synthase 0.32 ABI39_RS10205 3-isopropylmalate dehydratase small subunit low > 72
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS00930 cobyric acid synthase 0.32 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit low > 61
Hydrogenophaga sp. GW460-11-11-14-LB1 0.32 GFF3998 Cobyric acid synthase (EC 6.3.5.10) 0.43 GFF3361 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 90
Variovorax sp. SCN45 0.31 GFF426 Cobyric acid synthase (EC 6.3.5.10) 0.43 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 127
Acidovorax sp. GW101-3H11 0.31 Ac3H11_999 Cobyric acid synthase (EC 6.3.5.10) 0.43 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 79
Variovorax sp. OAS795 0.30 ABID97_RS17340 cobyric acid synthase 0.43 ABID97_RS08460 3-isopropylmalate dehydratase small subunit — —

Not shown: 6 genomes with orthologs for GFF66 only; 46 genomes with orthologs for GFF2628 only