Conservation of cofitness between GFF3277 and GFF2057 in Sphingobium sp. HT1-2

75 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF3277 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 1.0 GFF2057 Ketol-acid reductoisomerase (NADP(+)) (EC 1.1.1.86) 0.89 11
Sphingomonas koreensis DSMZ 15582 0.75 Ga0059261_2242 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 Ga0059261_0066 ketol-acid reductoisomerase (EC 1.1.1.86) — —
Azospirillum sp. SherDot2 0.64 MPMX19_02325 Bifunctional purine biosynthesis protein PurH 0.77 MPMX19_01774 Ketol-acid reductoisomerase (NADP(+)) — —
Phaeobacter inhibens DSM 17395 0.64 PGA1_c32860 bifunctional purine biosynthesis protein PurH 0.71 PGA1_c06580 ketol-acid reductoisomerase IlvC — —
Dinoroseobacter shibae DFL-12 0.63 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.70 Dshi_2396 ketol-acid reductoisomerase (RefSeq) — —
Xanthobacter sp. DMC5 0.63 GFF3847 Bifunctional purine biosynthesis protein PurH 0.73 GFF172 Ketol-acid reductoisomerase (NADP(+)) — —
Azospirillum brasilense Sp245 0.63 AZOBR_RS00225 purine biosynthesis protein purH 0.78 AZOBR_RS06570 ketol-acid reductoisomerase — —
Magnetospirillum magneticum AMB-1 0.62 AMB_RS00505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.76 AMB_RS17750 ketol-acid reductoisomerase — —
Rhodopseudomonas palustris CGA009 0.61 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.75 TX73_010485 ketol-acid reductoisomerase — —
Rhodospirillum rubrum S1H 0.59 Rru_A3655 Phosphoribosylaminoimidazolecarboxamideformyltransferase (NCBI) 0.77 Rru_A0469 Ketol-acid reductoisomerase (NCBI) — —
Sinorhizobium meliloti 1021 0.58 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.75 SMc04346 ketol-acid reductoisomerase 0.92 30
Rhizobium sp. OAE497 0.58 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.74 ABIE40_RS11360 ketol-acid reductoisomerase — —
Agrobacterium fabrum C58 0.58 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.73 Atu2019 ketol-acid reductoisomerase — —
Caulobacter crescentus NA1000 0.55 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.78 CCNA_02204 ketol-acid reductoisomerase/2-dehydropantoate 2-reductase — —
Caulobacter crescentus NA1000 Δfur 0.55 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.78 CCNA_02204 ketol-acid reductoisomerase/2-dehydropantoate 2-reductase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.55 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.49 A4249_RS05080 ketol-acid reductoisomerase — —
Acinetobacter baumannii LAC-4 0.52 RR41_RS06695 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.65 RR41_RS16325 ketol-acid reductoisomerase — —
Pseudomonas sp. DMC3 0.52 GFF3308 Bifunctional purine biosynthesis protein PurH 0.63 GFF4052 Ketol-acid reductoisomerase (NADP(+)) low > 89
Pseudomonas fluorescens FW300-N2E3 0.52 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.63 AO353_14505 ketol-acid reductoisomerase — —
Acinetobacter radioresistens SK82 0.52 MPMX26_01141 Bifunctional purine biosynthesis protein PurH 0.65 MPMX26_00474 Ketol-acid reductoisomerase (NADP(+)) 0.78 30
Pseudomonas fluorescens SBW25 0.51 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.64 PFLU_RS25640 ketol-acid reductoisomerase low > 109
Pseudomonas fluorescens SBW25-INTG 0.51 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.64 PFLU_RS25640 ketol-acid reductoisomerase — —
Pseudomonas lactucae CFBP13502 0.51 GEMAOFIL_00820 Bifunctional purine biosynthesis protein PurH 0.64 GEMAOFIL_04911 Ketol-acid reductoisomerase (NADP(+)) — —
Pseudomonas simiae WCS417 0.51 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.63 PS417_23800 ketol-acid reductoisomerase — —
Pseudomonas fluorescens FW300-N1B4 0.51 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.63 Pf1N1B4_2880 Ketol-acid reductoisomerase (EC 1.1.1.86) 0.83 10
Pseudomonas sp. RS175 0.51 PFR28_05214 Bifunctional purine biosynthesis protein PurH 0.62 PFR28_03697 Ketol-acid reductoisomerase (NADP(+)) — —
Pseudomonas fluorescens FW300-N2E2 0.51 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.62 Pf6N2E2_5177 Ketol-acid reductoisomerase (EC 1.1.1.86) — —
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.63 AO356_16180 ketol-acid reductoisomerase — —
Pseudomonas sp. SVBP6 0.51 COO64_RS18305 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.62 COO64_RS14995 ilvC ketol-acid reductoisomerase low > 93
Pseudomonas fluorescens GW456-L13 0.51 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.63 PfGW456L13_1540 Ketol-acid reductoisomerase (EC 1.1.1.86) — —
Pseudomonas sp. S08-1 0.51 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.63 OH686_08115 ketol-acid reductoisomerase — —
Ralstonia solanacearum GMI1000 0.51 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.67 RS_RS10410 ketol-acid reductoisomerase — —
Pseudomonas stutzeri RCH2 0.51 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.63 Psest_1038 ketol-acid reductoisomerase — —
Marinobacter adhaerens HP15 0.51 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.59 HP15_533 ketol-acid reductoisomerase — —
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.67 ABZR87_RS14945 ketol-acid reductoisomerase — —
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 0.63 Psyr_0848 ketol-acid reductoisomerase — —
Pseudomonas segetis P6 0.50 MPMX49_04108 Bifunctional purine biosynthesis protein PurH 0.64 MPMX49_01277 Ketol-acid reductoisomerase (NADP(+)) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 0.63 Psyr_0848 ketol-acid reductoisomerase — —
Ralstonia solanacearum UW163 0.50 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.67 UW163_RS10685 ketol-acid reductoisomerase — —
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.67 RALBFv3_RS03040 ketol-acid reductoisomerase — —
Ralstonia solanacearum PSI07 0.50 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.68 RPSI07_RS14265 ketol-acid reductoisomerase — —
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.68 RR42_RS05445 ketol-acid reductoisomerase — —
Pseudomonas putida KT2440 0.50 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.63 PP_4678 Ketol-acid reductoisomerase — —
Pseudomonas sp. BP01 0.50 JOY50_RS17625 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.63 JOY50_RS27770 ilvC ketol-acid reductoisomerase — —
Paraburkholderia bryophila 376MFSha3.1 0.50 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase 0.66 H281DRAFT_04553 ketol-acid reductoisomerase — —
Paraburkholderia graminis OAS925 0.50 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.65 ABIE53_001576 ketol-acid reductoisomerase — —
Paraburkholderia sabiae LMG 24235 0.50 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.66 QEN71_RS24215 ketol-acid reductoisomerase low > 153
Methylophilus sp. DMC18 0.49 GFF1644 Bifunctional purine biosynthesis protein PurH 0.66 GFF2519 Ketol-acid reductoisomerase (NADP(+)) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.49 GFF636 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.62 GFF4278 Ketol-acid reductoisomerase (EC 1.1.1.86) — —
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS16595 bifunctional purine biosynthesis protein PurH 0.66 BPHYT_RS06555 ketol-acid reductoisomerase — —
Dechlorosoma suillum PS 0.48 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.66 Dsui_3527 ketol-acid reductoisomerase — —
Pseudomonas aeruginosa PUPa3 0.48 DQ20_RS52005 purH;go_function=catalytic bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.64 DQ20_RS52825 ilvC;inference=COORDINATES ketol-acid reductoisomerase — —
Pseudomonas aeruginosa MRSN321 0.48 DY961_RS10050 purH;go_function=catalytic bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.64 DY961_RS09205 ilvC;inference=COORDINATES ketol-acid reductoisomerase 0.49 56
Pseudomonas aeruginosa PA14 0.48 IKLFDK_29290 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.64 IKLFDK_30155 ketol-acid reductoisomerase 0.44 53
Lysobacter sp. OAE881 0.48 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.49 ABIE51_RS17545 ketol-acid reductoisomerase low > 62
Castellaniella sp019104865 MT123 0.48 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.69 ABCV34_RS01220 ketol-acid reductoisomerase — —
Dyella japonica UNC79MFTsu3.2 0.48 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.51 ABZR86_RS15940 ketol-acid reductoisomerase — —
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS02060 purine biosynthesis protein purH 0.66 HSERO_RS08660 ketol-acid reductoisomerase — —
Acidovorax sp. GW101-3H11 0.47 Ac3H11_3994 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.62 Ac3H11_527 Ketol-acid reductoisomerase (EC 1.1.1.86) — —
Variovorax sp. SCN45 0.47 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.67 GFF1161 Ketol-acid reductoisomerase (NADP(+)) (EC 1.1.1.86) — —
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.659.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.52 Xcc-8004.1060.1 Ketol-acid reductoisomerase (EC 1.1.1.86) low > 74
Variovorax sp. OAS795 0.47 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.67 ABID97_RS14895 ketol-acid reductoisomerase — —
Rhodanobacter sp000427505 FW510-R12 0.46 LRK53_RS01585 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 LRK53_RS03090 ketol-acid reductoisomerase 0.54 13
Rhodanobacter denitrificans MT42 0.46 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 LRK55_RS09955 ketol-acid reductoisomerase low > 63
Rhodanobacter sp. FW510-T8 0.46 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.52 OKGIIK_13605 ilvC ketol-acid reductoisomerase low > 53
Rhodanobacter denitrificans FW104-10B01 0.46 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.53 LRK54_RS10315 ketol-acid reductoisomerase — —
Synechocystis sp000284455 PCC 6803 0.45 SGL_RS18300 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.59 SGL_RS17215 ketol-acid reductoisomerase — —
Synechococcus elongatus PCC 7942 0.43 Synpcc7942_0396 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.63 Synpcc7942_1552 ilvC ketol-acid reductoisomerase — —
Mycobacterium tuberculosis H37Rv 0.41 Rv0957 Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC) 0.55 Rv3001c Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) (alpha-keto-beta-hydroxylacil reductoisomerase) — —
Bifidobacterium breve UCC2003 0.41 BBR_RS15690 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.49 BBR_RS10830 ketol-acid reductoisomerase — —
Bacteroides stercoris CC31F 0.38 HMPREF1181_RS00165 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.19 HMPREF1181_RS08315 ketol-acid reductoisomerase 0.84 53
Bacteroides ovatus ATCC 8483 0.37 BACOVA_03657 putative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.19 BACOVA_03306 ketol-acid reductoisomerase low > 96
Bacteroides thetaiotaomicron VPI-5482 0.37 BT3812 phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH (NCBI ptt file) 0.19 BT2074 ketol-acid reductoisomerase (NCBI ptt file) low > 81
Pontibacter actiniarum KMM 6156, DSM 19842 0.36 CA264_18630 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.22 CA264_06920 ketol-acid reductoisomerase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.36 ABZR88_RS16970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.19 ABZR88_RS11590 ketol-acid reductoisomerase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.35 Echvi_1469 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) 0.20 Echvi_2058 ketol-acid reductoisomerase — —

Not shown: 44 genomes with orthologs for GFF3277 only; 4 genomes with orthologs for GFF2057 only