Conservation of cofitness between CSW01_12100 and CSW01_18760 in Vibrio cholerae E7946 ATCC 55056

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12100 carbamoyl-phosphate synthase large chain 1.0 CSW01_18760 dihydroorotase 0.90 3
Klebsiella michiganensis M5al 0.87 BWI76_RS04470 carbamoyl phosphate synthase large subunit 0.55 BWI76_RS10990 dihydroorotase 0.81 4
Klebsiella pneumoniae MKP103 0.87 KDGMDA_12710 carbamoyl-phosphate synthase large subunit 0.56 KDGMDA_18610 dihydroorotase low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF213 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.53 GFF3342 Dihydroorotase (EC 3.5.2.3) 0.58 5
Escherichia coli BL21 0.87 ECD_00037 carbamoyl-phosphate synthase large subunit 0.55 ECD_01058 dihydro-orotase 0.88 7
Escherichia coli ECRC62 0.87 BNILDI_08330 carB carbamoyl-phosphate synthase large subunit 0.55 BNILDI_19420 pyrC dihydroorotase 0.92 14
Escherichia coli HS(pFamp)R (ATCC 700891) 0.87 OHPLBJKB_03624 Carbamoyl-phosphate synthase large chain 0.55 OHPLBJKB_02603 Dihydroorotase 0.70 6
Shewanella loihica PV-4 0.87 Shew_2838 carB carbamoyl phosphate synthase large subunit (RefSeq) 0.74 Shew_0728 dihydroorotase (RefSeq) 0.92 10
Escherichia coli ECOR27 0.87 NOLOHH_03270 carB carbamoyl-phosphate synthase large subunit 0.55 NOLOHH_21260 pyrC dihydroorotase 0.96 8
Enterobacter asburiae PDN3 0.87 EX28DRAFT_3638 carbamoyl-phosphate synthase, large subunit 0.57 EX28DRAFT_1869 dihydroorotase (EC 3.5.2.3) — —
Escherichia fergusonii Becca 0.87 EFB2_04012 Carbamoyl-phosphate synthase large chain 0.55 EFB2_02912 Dihydroorotase low > 86
Escherichia coli ECOR38 0.87 HEPCGN_08925 carB carbamoyl-phosphate synthase large subunit 0.55 HEPCGN_23760 pyrC dihydroorotase 0.94 10
Escherichia coli BW25113 0.87 b0033 carB carbamoyl-phosphate synthase large subunit (NCBI) 0.55 b1062 pyrC dihydroorotase (NCBI) 0.89 4
Escherichia coli ECRC102 0.87 NIAGMN_08790 carB carbamoyl-phosphate synthase large subunit 0.55 NIAGMN_24100 pyrC dihydroorotase low > 80
Escherichia coli ECRC99 0.87 KEDOAH_17215 carB carbamoyl-phosphate synthase large subunit 0.55 KEDOAH_24025 pyrC dihydroorotase — —
Escherichia coli ECRC98 0.87 JDDGAC_14535 carB carbamoyl-phosphate synthase large subunit 0.55 JDDGAC_07390 pyrC dihydroorotase low > 87
Shewanella amazonensis SB2B 0.87 Sama_2503 carB carbamoyl phosphate synthase large subunit (RefSeq) 0.77 Sama_2870 dihydroorotase (RefSeq) 0.82 7
Escherichia coli ECRC101 0.87 MCAODC_01455 carB carbamoyl-phosphate synthase large subunit 0.55 MCAODC_23090 pyrC dihydroorotase 0.83 9
Escherichia coli ECRC100 0.87 OKFHMN_10940 carB carbamoyl-phosphate synthase large subunit 0.55 OKFHMN_03730 pyrC dihydroorotase 0.95 7
Escherichia coli Nissle 1917 0.87 ECOLIN_RS00180 carbamoyl-phosphate synthase large subunit 0.55 ECOLIN_RS06160 dihydroorotase 0.92 3
Enterobacter sp. TBS_079 0.87 MPMX20_00740 Carbamoyl-phosphate synthase large chain 0.57 MPMX20_01741 Dihydroorotase 0.89 18
Pectobacterium carotovorum WPP14 0.87 HER17_RS02900 carbamoyl-phosphate synthase large subunit 0.56 HER17_RS08600 dihydroorotase 0.97 21
Shewanella sp. ANA-3 0.86 Shewana3_0968 carB carbamoyl phosphate synthase large subunit (RefSeq) 0.77 Shewana3_3263 dihydroorotase (RefSeq) 0.90 52
Shewanella oneidensis MR-1 0.86 SO1142 carB carbamoyl-phosphate synthase, large subunit (NCBI ptt file) 0.75 SO3695 pyrC dihydroorotase, homodimeric type (NCBI ptt file) 0.90 40
Rahnella sp. WP5 0.86 EX31_RS03830 carbamoyl-phosphate synthase large subunit 0.55 EX31_RS24385 dihydroorotase 0.95 41
Dickeya dadantii 3937 0.86 DDA3937_RS18305 carbamoyl-phosphate synthase large subunit 0.56 DDA3937_RS13170 dihydroorotase 0.73 62
Dickeya dianthicola ME23 0.86 DZA65_RS19380 carbamoyl-phosphate synthase large subunit 0.55 DZA65_RS13710 dihydroorotase 0.76 29
Dickeya dianthicola 67-19 0.86 HGI48_RS18240 carbamoyl-phosphate synthase large subunit 0.55 HGI48_RS13235 dihydroorotase 0.83 8
Pantoea sp. MT58 0.86 IAI47_16115 carbamoyl-phosphate synthase large subunit 0.54 IAI47_12215 dihydroorotase 0.88 30
Pantoea agglomerans CFBP13505 P0401 0.85 PagCFBP13505_RS12880 carbamoyl-phosphate synthase large subunit 0.55 PagCFBP13505_RS05115 dihydroorotase 0.58 53
Serratia liquefaciens MT49 0.85 IAI46_03195 carbamoyl-phosphate synthase large subunit 0.57 IAI46_09740 dihydroorotase 0.90 5
Erwinia tracheiphila SCR3 0.85 LU632_RS02750 carB carbamoyl-phosphate synthase large subunit 0.57 LU632_RS10340 pyrC dihydroorotase 0.99 1
Erwinia tracheiphila HP pepo 2.2 0.85 IJEDHG_06145 carB carbamoyl-phosphate synthase large subunit 0.57 IJEDHG_20990 pyrC dihydroorotase 0.93 7
Erwinia amylovora T8 0.84 OLJFJH_01395 carbamoyl-phosphate synthase large subunit 0.56 OLJFJH_15670 dihydroorotase low > 58
Alteromonas macleodii MIT1002 0.81 MIT1002_01467 Carbamoyl-phosphate synthase large chain 0.61 MIT1002_03750 Dihydroorotase — —
Pseudomonas lactucae CFBP13502 0.76 GEMAOFIL_04958 Carbamoyl-phosphate synthase large chain 0.66 GEMAOFIL_01313 Dihydroorotase — —
Pseudomonas aeruginosa PA14 0.76 IKLFDK_29815 carbamoyl-phosphate synthase large subunit 0.66 IKLFDK_18005 dihydroorotase — —
Pseudomonas aeruginosa PUPa3 0.76 DQ20_RS52500 carB;go_function=ATP carbamoyl-phosphate synthase large subunit 0.66 DQ20_RS41770 pyrC;go_function=dihydroorotase dihydroorotase — —
Pseudomonas simiae WCS417 0.76 PS417_24040 carbamoyl phosphate synthase large subunit 0.66 PS417_05630 dihydroorotase — —
Pseudomonas fluorescens FW300-N1B4 0.76 Pf1N1B4_1172 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.67 Pf1N1B4_744 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas aeruginosa MRSN321 0.76 DY961_RS09535 carB;go_function=ATP carbamoyl-phosphate synthase large subunit 0.66 DY961_RS15380 pyrC;go_function=dihydroorotase dihydroorotase — —
Pseudomonas fluorescens GW456-L13 0.76 PfGW456L13_5099 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.67 PfGW456L13_1747 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas sp. DMC3 0.76 GFF4977 Carbamoyl-phosphate synthase large chain 0.67 GFF5094 Dihydroorotase — —
Pseudomonas sp. RS175 0.76 PFR28_00077 Carbamoyl-phosphate synthase large chain 0.67 PFR28_03355 Dihydroorotase — —
Pseudomonas fluorescens FW300-N2E3 0.76 AO353_05630 carbamoyl phosphate synthase large subunit 0.67 AO353_04115 dihydroorotase — —
Pseudomonas fluorescens SBW25-INTG 0.76 PFLU_RS25880 carbamoyl-phosphate synthase large subunit 0.66 PFLU_RS05715 dihydroorotase — —
Pseudomonas fluorescens SBW25 0.76 PFLU_RS25880 carbamoyl-phosphate synthase large subunit 0.66 PFLU_RS05715 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.76 Psyr_4191 carbamoyl-phosphate synthase large subunit 0.67 Psyr_3894 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a 0.76 Psyr_4191 carbamoyl-phosphate synthase large subunit 0.67 Psyr_3894 dihydroorotase — —
Pseudomonas orientalis W4I3 0.76 QF045_RS26295 carbamoyl-phosphate synthase large subunit 0.66 QF045_RS08555 dihydroorotase — —
Pseudomonas sp. S08-1 0.75 OH686_17080 Carbamoyl-phosphate synthase large chain 0.66 OH686_03940 dihydroorotase, homodimeric type — —
Pseudomonas putida KT2440 0.75 PP_4723 Carbamoyl-phosphate synthase large chain 0.66 PP_1086 dihydroorotase — —
Pseudomonas fluorescens FW300-N2C3 0.75 AO356_07480 carbamoyl phosphate synthase large subunit 0.66 AO356_18315 dihydroorotase — —
Pseudomonas stutzeri RCH2 0.75 Psest_0968 carbamoyl-phosphate synthase, large subunit 0.66 Psest_3123 dihydroorotase, homodimeric type — —
Pseudomonas fluorescens FW300-N2E2 0.75 Pf6N2E2_3364 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.66 Pf6N2E2_5588 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas sp. BP01 0.75 JOY50_RS26765 carB carbamoyl-phosphate synthase large subunit 0.66 JOY50_RS14925 pyrC dihydroorotase — —
Pseudomonas sp. SVBP6 0.75 COO64_RS15240 carB carbamoyl-phosphate synthase large subunit 0.67 COO64_RS16860 pyrC dihydroorotase — —
Pseudomonas segetis P6 0.75 MPMX49_01187 Carbamoyl-phosphate synthase large chain 0.67 MPMX49_01445 Dihydroorotase — —
Marinobacter adhaerens HP15 0.75 HP15_3077 carbamoyl-phosphate synthase, large subunit 0.65 HP15_1216 dihydroorotase, homodimeric type — —
Acinetobacter baumannii LAC-4 0.74 RR41_RS04155 carbamoyl-phosphate synthase large subunit 0.59 RR41_RS09355 dihydroorotase — —
Acinetobacter radioresistens SK82 0.73 MPMX26_00766 Carbamoyl-phosphate synthase large chain 0.59 MPMX26_02262 Dihydroorotase — —
Kangiella aquimarina DSM 16071 0.73 B158DRAFT_0616 carbamoyl-phosphate synthase, large subunit 0.67 B158DRAFT_1241 dihydroorotase (EC 3.5.2.3) — —
Methylophilus sp. DMC18 0.73 GFF312 Carbamoyl-phosphate synthase large chain 0.61 GFF2451 Dihydroorotase — —
Rhodanobacter denitrificans FW104-10B01 0.69 LRK54_RS18000 carbamoyl-phosphate synthase large subunit 0.59 LRK54_RS10900 dihydroorotase — —
Rhodanobacter denitrificans MT42 0.69 LRK55_RS17855 carbamoyl-phosphate synthase large subunit 0.57 LRK55_RS10600 dihydroorotase — —
Rhodanobacter sp. FW510-T8 0.69 OKGIIK_07295 carB carbamoyl-phosphate synthase large subunit 0.57 OKGIIK_12970 pyrC dihydroorotase — —
Rhodanobacter sp000427505 FW510-R12 0.69 LRK53_RS11360 carbamoyl-phosphate synthase large subunit 0.59 LRK53_RS03690 dihydroorotase — —
Dechlorosoma suillum PS 0.68 Dsui_3064 carbamoyl-phosphate synthase, large subunit 0.60 Dsui_0250 dihydroorotase, homodimeric type — —
Acidovorax sp. GW101-3H11 0.67 Ac3H11_436 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.62 Ac3H11_1963 Dihydroorotase (EC 3.5.2.3) — —
Ralstonia solanacearum PSI07 0.67 RPSI07_RS15255 carbamoyl-phosphate synthase large subunit 0.64 RPSI07_RS21625 dihydroorotase — —
Herbaspirillum seropedicae SmR1 0.67 HSERO_RS06925 carbamoyl phosphate synthase large subunit 0.62 HSERO_RS19235 dihydroorotase — —
Ralstonia sp. UNC404CL21Col 0.67 ABZR87_RS14140 carbamoyl-phosphate synthase large subunit 0.65 ABZR87_RS07550 dihydroorotase — —
Ralstonia solanacearum IBSBF1503 0.67 RALBFv3_RS02190 carbamoyl-phosphate synthase large subunit 0.64 RALBFv3_RS11590 dihydroorotase — —
Ralstonia solanacearum UW163 0.67 UW163_RS15500 carbamoyl-phosphate synthase large subunit 0.64 UW163_RS01995 dihydroorotase — —
Paraburkholderia graminis OAS925 0.66 ABIE53_003004 carbamoyl-phosphate synthase large subunit 0.62 ABIE53_003505 dihydroorotase — —
Burkholderia phytofirmans PsJN 0.66 BPHYT_RS14190 carbamoyl phosphate synthase large subunit 0.61 BPHYT_RS16675 dihydroorotase 0.84 9
Paraburkholderia bryophila 376MFSha3.1 0.66 H281DRAFT_04403 carbamoyl-phosphate synthase large subunit 0.61 H281DRAFT_04265 dihydroorotase — —
Variovorax sp. OAS795 0.66 ABID97_RS17080 carbamoyl-phosphate synthase large subunit 0.59 ABID97_RS06040 dihydroorotase — —
Ralstonia solanacearum GMI1000 0.66 RS_RS07630 carbamoyl-phosphate synthase large chain 0.65 RS_RS02420 dihydroorotase — —
Castellaniella sp019104865 MT123 0.66 ABCV34_RS15510 carbamoyl-phosphate synthase large subunit 0.57 ABCV34_RS09730 dihydroorotase — —
Cupriavidus basilensis FW507-4G11 0.66 RR42_RS13510 carbamoyl phosphate synthase large subunit 0.62 RR42_RS02610 dihydroorotase — —
Paraburkholderia sabiae LMG 24235 0.66 QEN71_RS04780 carbamoyl-phosphate synthase large subunit 0.61 QEN71_RS26855 dihydroorotase — —
Variovorax sp. SCN45 0.66 GFF376 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.59 GFF4557 Dihydroorotase (EC 3.5.2.3) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.66 GFF4898 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) 0.61 GFF523 Dihydroorotase (EC 3.5.2.3) — —
Dinoroseobacter shibae DFL-12 0.59 Dshi_2639 carbamoyl-phosphate synthase, large subunit (RefSeq) 0.51 Dshi_2371 dihydroorotase, homodimeric type (RefSeq) 0.79 10
Azospirillum brasilense Sp245 0.59 AZOBR_RS12895 carbamoyl phosphate synthase large subunit 0.52 AZOBR_RS04460 dihydroorotase — —
Sinorhizobium meliloti 1021 0.59 SMc01215 carbamoyl phosphate synthase large subunit 0.53 SMc02166 dihydroorotase 0.73 18
Rhizobium sp. OAE497 0.59 ABIE40_RS12815 carbamoyl-phosphate synthase large subunit 0.52 ABIE40_RS02105 dihydroorotase — —
Azospirillum sp. SherDot2 0.59 MPMX19_02299 Carbamoyl-phosphate synthase large chain 0.53 MPMX19_01633 Dihydroorotase — —
Agrobacterium fabrum C58 0.58 Atu2178 carbamoylphosphate synthase large subunit 0.53 Atu0399 dihydroorotase — —
Phaeobacter inhibens DSM 17395 0.58 PGA1_c24560 carbamoyl-phosphate synthase large chain 0.52 PGA1_c10910 dihydroorotase PyrC 0.76 20
Synechocystis sp000284455 PCC 6803 0.57 SGL_RS14530 carbamoyl-phosphate synthase large subunit 0.57 SGL_RS12080 dihydroorotase — —

Not shown: 32 genomes with orthologs for CSW01_12100 only; 0 genomes with orthologs for CSW01_18760 only