Conservation of cofitness between CSW01_04845 and CSW01_15330 in Vibrio cholerae E7946 ATCC 55056

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04845 D-alanyl-D-alanine carboxypeptidase 1.0 CSW01_15330 glycine dehydrogenase (decarboxylating) 0.62 17
Shewanella sp. ANA-3 0.69 Shewana3_0991 penicillin-binding protein 6 (RefSeq) 0.58 Shewana3_3499 glycine dehydrogenase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.69 SO1164 dacA-1 D-alanyl-D-alanine carboxypeptidase (NCBI ptt file) 0.58 SO0781 gcvP glycine cleavage system P protein (NCBI ptt file) — —
Shewanella amazonensis SB2B 0.69 Sama_2592 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) 0.58 Sama_2719 glycine dehydrogenase (RefSeq) — —
Shewanella loihica PV-4 0.68 Shew_2939 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) 0.59 Shew_3062 glycine dehydrogenase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.62 MIT1002_01848 D-alanyl-D-alanine carboxypeptidase DacC precursor 0.63 MIT1002_02971 Glycine dehydrogenase [decarboxylating] — —
Pectobacterium carotovorum WPP14 0.58 HER17_RS15260 D-alanyl-D-alanine carboxypeptidase DacA 0.58 HER17_RS17995 aminomethyl-transferring glycine dehydrogenase low > 75
Dickeya dianthicola 67-19 0.57 HGI48_RS06200 D-alanyl-D-alanine carboxypeptidase DacA 0.58 HGI48_RS03400 aminomethyl-transferring glycine dehydrogenase low > 71
Rahnella sp. WP5 0.57 EX31_RS23105 D-alanyl-D-alanine carboxypeptidase DacA 0.58 EX31_RS21520 aminomethyl-transferring glycine dehydrogenase low > 89
Pantoea sp. MT58 0.57 IAI47_14040 D-alanyl-D-alanine carboxypeptidase DacA 0.59 IAI47_03775 aminomethyl-transferring glycine dehydrogenase low > 76
Dickeya dadantii 3937 0.57 DDA3937_RS06155 D-alanyl-D-alanine carboxypeptidase DacA 0.58 DDA3937_RS03255 aminomethyl-transferring glycine dehydrogenase low > 74
Pantoea agglomerans CFBP13505 P0401 0.56 PagCFBP13505_RS03265 D-alanyl-D-alanine carboxypeptidase DacA 0.59 PagCFBP13505_RS15925 aminomethyl-transferring glycine dehydrogenase low > 74
Erwinia tracheiphila HP pepo 2.2 0.56 IJEDHG_02480 D-alanyl-D-alanine carboxypeptidase DacC 0.58 IJEDHG_03250 gcvP aminomethyl-transferring glycine dehydrogenase low > 61
Dickeya dianthicola ME23 0.56 DZA65_RS06545 D-alanyl-D-alanine carboxypeptidase DacA 0.58 DZA65_RS03445 aminomethyl-transferring glycine dehydrogenase low > 75
Erwinia tracheiphila SCR3 0.56 LU632_RS16390 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.58 LU632_RS05915 gcvP aminomethyl-transferring glycine dehydrogenase low > 73
Serratia liquefaciens MT49 0.56 IAI46_05915 D-alanyl-D-alanine carboxypeptidase DacA 0.58 IAI46_20850 aminomethyl-transferring glycine dehydrogenase low > 87
Klebsiella pneumoniae MKP103 0.55 KDGMDA_16380 D-alanyl-D-alanine carboxypeptidase DacA 0.59 KDGMDA_04370 aminomethyl-transferring glycine dehydrogenase low > 95
Erwinia amylovora T8 0.55 OLJFJH_17245 D-alanyl-D-alanine carboxypeptidase DacA 0.59 OLJFJH_08785 aminomethyl-transferring glycine dehydrogenase low > 58
Enterobacter sp. TBS_079 0.55 MPMX20_01291 D-alanyl-D-alanine carboxypeptidase DacA 0.59 MPMX20_03762 Glycine dehydrogenase (decarboxylating) low > 85
Escherichia coli BW25113 0.55 b0632 dacA D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) 0.59 b2903 gcvP glycine dehydrogenase (NCBI) low > 76
Escherichia coli ECRC101 0.55 MCAODC_26595 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 MCAODC_10050 gcvP aminomethyl-transferring glycine dehydrogenase low > 87
Escherichia coli ECRC99 0.55 KEDOAH_20590 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 KEDOAH_08610 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli ECRC100 0.55 OKFHMN_07380 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 OKFHMN_19530 gcvP aminomethyl-transferring glycine dehydrogenase low > 79
Escherichia coli Nissle 1917 0.55 ECOLIN_RS03445 D-alanyl-D-alanine carboxypeptidase DacA 0.59 ECOLIN_RS16165 aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli ECOR38 0.55 HEPCGN_00895 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 HEPCGN_18820 gcvP aminomethyl-transferring glycine dehydrogenase low > 88
Escherichia coli ECRC62 0.55 BNILDI_21765 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 BNILDI_09980 gcvP aminomethyl-transferring glycine dehydrogenase low > 75
Escherichia coli ECRC98 0.55 JDDGAC_11025 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 JDDGAC_23170 gcvP aminomethyl-transferring glycine dehydrogenase low > 87
Escherichia coli ECRC102 0.55 NIAGMN_05435 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 NIAGMN_17295 gcvP aminomethyl-transferring glycine dehydrogenase low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_03074 D-alanyl-D-alanine carboxypeptidase DacA 0.59 OHPLBJKB_00812 Glycine dehydrogenase (decarboxylating) low > 74
Escherichia coli BL21 0.55 ECD_00601 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) 0.59 ECD_02735 glycine decarboxylase, PLP-dependent, subunit P of glycine cleavage complex low > 61
Klebsiella michiganensis M5al 0.55 BWI76_RS08020 serine-type D-Ala-D-Ala carboxypeptidase 0.59 BWI76_RS23870 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF4545 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.59 GFF3003 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 78
Escherichia coli ECOR27 0.55 NOLOHH_23755 dacA D-alanyl-D-alanine carboxypeptidase DacA 0.59 NOLOHH_11445 gcvP aminomethyl-transferring glycine dehydrogenase low > 76
Enterobacter asburiae PDN3 0.55 EX28DRAFT_2331 D-alanyl-D-alanine carboxypeptidase 0.59 EX28DRAFT_2955 glycine dehydrogenase (decarboxylating) low > 76
Escherichia fergusonii Becca 0.54 EFB2_03460 D-alanyl-D-alanine carboxypeptidase DacA 0.59 EFB2_00999 Glycine dehydrogenase (decarboxylating) low > 86
Kangiella aquimarina DSM 16071 0.50 B158DRAFT_0079 D-alanyl-D-alanine carboxypeptidase 0.59 B158DRAFT_0545 glycine dehydrogenase (decarboxylating) — —
Pseudomonas sp. RS175 0.47 PFR28_03864 D-alanyl-D-alanine carboxypeptidase DacC 0.56 PFR28_03383 Glycine dehydrogenase (decarboxylating) low > 88
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_4361 penicillin-binding protein 6, Serine peptidase, MEROPS family S11 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit 0.43 36
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_4361 penicillin-binding protein 6, Serine peptidase, MEROPS family S11 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit low > 86
Pseudomonas fluorescens FW300-N2E2 0.46 Pf6N2E2_5001 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.56 Pf6N2E2_5558 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) low > 103
Pseudomonas fluorescens FW300-N1B4 0.46 Pf1N1B4_2696 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.59 Pf1N1B4_2236 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) — —
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_15330 D-alanyl-D-alanine carboxypeptidase 0.56 AO356_18170 glycine dehydrogenase low > 104
Pseudomonas sp. SVBP6 0.46 COO64_RS15590 D-alanyl-D-alanine carboxypeptidase family protein 0.58 COO64_RS00950 gcvP aminomethyl-transferring glycine dehydrogenase low > 93
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_06455 D-alanyl-D-alanine carboxypeptidase 0.58 AO353_08720 glycine dehydrogenase low > 101
Pseudomonas sp. DMC3 0.46 GFF3884 D-alanyl-D-alanine carboxypeptidase DacC 0.58 GFF308 Glycine dehydrogenase (decarboxylating) low > 89
Pseudomonas segetis P6 0.46 ACVTMO_RS05235 D-alanyl-D-alanine carboxypeptidase family protein 0.59 ACVTMO_RS22225 gcvP aminomethyl-transferring glycine dehydrogenase low > 75
Pseudomonas fluorescens GW456-L13 0.46 PfGW456L13_1364 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.58 PfGW456L13_904 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) — —
Pseudomonas stutzeri RCH2 0.46 Psest_0516 D-alanyl-D-alanine carboxypeptidase 0.60 Psest_0183 glycine dehydrogenase (decarboxylating) low > 67
Pseudomonas fluorescens SBW25 0.46 PFLU_RS26635 D-alanyl-D-alanine carboxypeptidase 0.57 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase 0.56 68
Pseudomonas simiae WCS417 0.46 PS417_24705 D-alanyl-D-alanine carboxypeptidase 0.57 PS417_22360 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) low > 88
Pseudomonas fluorescens SBW25-INTG 0.46 PFLU_RS26635 D-alanyl-D-alanine carboxypeptidase 0.57 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase low > 109
Pseudomonas orientalis W4I3 0.46 QF045_RS26990 D-alanyl-D-alanine carboxypeptidase family protein 0.57 QF045_RS24485 aminomethyl-transferring glycine dehydrogenase — —
Pseudomonas lactucae CFBP13502 0.46 GEMAOFIL_05094 D-alanyl-D-alanine carboxypeptidase DacC 0.57 GEMAOFIL_04608 Glycine dehydrogenase (decarboxylating) low > 96
Pseudomonas sp. BP01 0.45 JOY50_RS17720 D-alanyl-D-alanine carboxypeptidase family protein 0.59 JOY50_RS22405 gcvP aminomethyl-transferring glycine dehydrogenase low > 84
Pseudomonas putida KT2440 0.45 PP_4803 D-alanyl-D-alanine carboxypeptidase 0.58 PP_5192 glycine dehydrogenase low > 96
Pseudomonas sp. S08-1 0.45 OH686_09300 D-alanyl-D-alanine carboxypeptidase 0.60 OH686_11165 glycine dehydrogenase low > 80
Pseudomonas aeruginosa PA14 0.45 IKLFDK_20625 serine-type D-Ala-D-Ala carboxypeptidase 0.57 IKLFDK_27405 aminomethyl-transferring glycine dehydrogenase low > 98
Pseudomonas aeruginosa PUPa3 0.45 DQ20_RS48190 D-alanyl-D-alanine carboxypeptidase family protein 0.57 DQ20_RS50180 gcvP;go_function=glycine aminomethyl-transferring glycine dehydrogenase low > 101
Pseudomonas aeruginosa MRSN321 0.45 DY961_RS12860 D-alanyl-D-alanine carboxypeptidase family protein 0.57 DY961_RS11935 gcvP;go_function=glycine aminomethyl-transferring glycine dehydrogenase low > 100
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.907.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.55 Xcc-8004.3878.1 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 74
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_00090 serine-type D-Ala-D-Ala carboxypeptidase 0.55 OKGIIK_06740 gcvP2 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain low > 53
Rhodanobacter sp000427505 FW510-R12 0.41 LRK53_RS17780 D-alanyl-D-alanine carboxypeptidase 0.54 LRK53_RS09610 aminomethyl-transferring glycine dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.41 LRK54_RS06490 D-alanyl-D-alanine carboxypeptidase 0.56 LRK54_RS00520 aminomethyl-transferring glycine dehydrogenase low > 59
Rhodanobacter denitrificans MT42 0.41 LRK55_RS06235 D-alanyl-D-alanine carboxypeptidase family protein 0.56 LRK55_RS00260 aminomethyl-transferring glycine dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS17490 D-alanyl-D-alanine carboxypeptidase family protein 0.57 ABZR86_RS08305 aminomethyl-transferring glycine dehydrogenase — —
Lysobacter sp. OAE881 0.40 ABIE51_RS03165 D-alanyl-D-alanine carboxypeptidase family protein 0.55 ABIE51_RS14345 aminomethyl-transferring glycine dehydrogenase low > 62
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS01680 cytochrome C550 0.56 RR42_RS20070 glycine dehydrogenase low > 128
Dechlorosoma suillum PS 0.37 Dsui_0899 D-alanyl-D-alanine carboxypeptidase 0.60 Dsui_2737 glycine dehydrogenase, decarboxylating low > 51
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS02415 cytochrome C550 0.58 BPHYT_RS19330 glycine cleavage system P protein (EC 1.4.4.2) (from data) low > 109
Ralstonia solanacearum PSI07 0.36 RPSI07_RS22545 D-alanyl-D-alanine carboxypeptidase 0.57 RPSI07_RS08575 glycine dehydrogenase (aminomethyl-transferring) low > 81
Ralstonia sp. UNC404CL21Col 0.36 ABZR87_RS06610 D-alanyl-D-alanine carboxypeptidase family protein 0.56 ABZR87_RS03935 aminomethyl-transferring glycine dehydrogenase low > 80
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS01300 D-alanyl-D-alanine carboxypeptidase family protein 0.57 QEN71_RS29215 aminomethyl-transferring glycine dehydrogenase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_02054 penicillin-binding protein 6. Serine peptidase. MEROPS family S11 0.58 H281DRAFT_02409 glycine dehydrogenase low > 103
Paraburkholderia graminis OAS925 0.36 ABIE53_000626 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) 0.58 ABIE53_000238 glycine dehydrogenase low > 113
Ralstonia solanacearum GMI1000 0.35 RS_RS01610 D-alanyl-D-alanine carboxypeptidase 0.56 RS_RS16510 glycine dehydrogenase low > 80
Castellaniella sp019104865 MT123 0.34 ABCV34_RS13340 D-alanyl-D-alanine carboxypeptidase family protein 0.54 ABCV34_RS08835 aminomethyl-transferring glycine dehydrogenase low > 48
Ralstonia solanacearum UW163 0.34 UW163_RS02810 D-alanyl-D-alanine carboxypeptidase 0.57 UW163_RS04950 glycine dehydrogenase (aminomethyl-transferring) — —
Ralstonia solanacearum IBSBF1503 0.34 RALBFv3_RS10770 D-alanyl-D-alanine carboxypeptidase 0.57 RALBFv3_RS08660 glycine dehydrogenase (aminomethyl-transferring) low > 76
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF1806 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.54 GFF5215 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 90
Variovorax sp. OAS795 0.32 ABID97_RS00695 D-alanyl-D-alanine carboxypeptidase family protein 0.56 ABID97_RS19655 aminomethyl-transferring glycine dehydrogenase low > 91
Acidovorax sp. GW101-3H11 0.32 Ac3H11_2142 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) 0.54 Ac3H11_167 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) — —
Phaeobacter inhibens DSM 17395 0.26 PGA1_c08020 D-alanyl-D-alanine carboxypeptidase DacC 0.56 PGA1_78p00310 glycine dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.26 TX73_014370 D-alanyl-D-alanine carboxypeptidase 0.57 TX73_019935 aminomethyl-transferring glycine dehydrogenase low > 86
Dinoroseobacter shibae DFL-12 0.25 Dshi_0923 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) 0.55 Dshi_2680 glycine dehydrogenase (RefSeq) — —
Sinorhizobium meliloti 1021 0.22 SMc01188 penicillin-binding precursor (D-alanyl-D-alanine carboxypeptidase fraction A) transmembrane protein 0.55 SMc02049 glycine dehydrogenase — —
Agrobacterium fabrum C58 0.21 Atu1499 penicillin binding protein 0.54 Atu1462 glycine cleavage system protein P2 low > 89

Not shown: 13 genomes with orthologs for CSW01_04845 only; 16 genomes with orthologs for CSW01_15330 only