Conservation of cofitness between CSW01_00850 and CSW01_09605 in Vibrio cholerae E7946 ATCC 55056

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00850 multidrug resistance protein 1.0 CSW01_09605 endopeptidase La 0.61 16
Shewanella sp. ANA-3 0.72 Shewana3_0371 acriflavin resistance protein (RefSeq) 0.82 Shewana3_2659 Lon-A peptidase (RefSeq) — —
Shewanella amazonensis SB2B 0.71 Sama_3269 putative multidrug resistance protein (RefSeq) 0.81 Sama_1226 endopeptidase La (RefSeq) low > 62
Rhodospirillum rubrum S1H 0.49 Rru_A3699 Acriflavin resistance protein (NCBI) 0.65 Rru_A1552 Peptidase S16, ATP-dependent protease La (NCBI) low > 58
Azospirillum brasilense Sp245 0.49 AZOBR_RS31320 acriflavine resistance protein B 0.66 AZOBR_RS07145 peptidase low > 97
Magnetospirillum magneticum AMB-1 0.48 AMB_RS17260 acriflavine resistance protein B 0.66 AMB_RS14035 endopeptidase La low > 64
Pseudomonas segetis P6 0.48 MPMX49_03771 Multidrug efflux pump subunit AcrB 0.69 MPMX49_02263 Lon protease low > 75
Rhodopseudomonas palustris CGA009 0.48 TX73_019545 MexW/MexI family multidrug efflux RND transporter permease subunit 0.63 TX73_015345 endopeptidase La — —
Azospirillum sp. SherDot2 0.48 MPMX19_05610 Efflux pump membrane transporter BepE 0.66 MPMX19_01545 Lon protease low > 112
Pseudomonas simiae WCS417 0.47 PS417_22755 acriflavine resistance protein B 0.68 PS417_17225 DNA-binding protein — —
Pseudomonas fluorescens SBW25 0.47 PFLU_RS24405 multidrug efflux RND transporter permease subunit 0.68 PFLU_RS19160 endopeptidase La low > 109
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS24405 multidrug efflux RND transporter permease subunit 0.68 PFLU_RS19160 endopeptidase La low > 109
Pseudomonas sp. RS175 0.47 PFR28_03330 Multidrug efflux pump subunit AcrB 0.68 PFR28_01230 Lon protease low > 88
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_18440 acriflavine resistance protein B 0.68 AO356_01740 DNA-binding protein low > 104
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_5614 RND multidrug efflux transporter; Acriflavin resistance protein 0.68 Pf6N2E2_2216 ATP-dependent protease La (EC 3.4.21.53) Type I — —
Pseudomonas sp. S08-1 0.47 OH686_17360 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) 0.68 OH686_03635 endopeptidase La low > 80
Pseudomonas sp. BP01 0.47 JOY50_RS14955 multidrug efflux RND transporter permease subunit 0.67 JOY50_RS25905 lon endopeptidase La low > 84
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_720 RND multidrug efflux transporter; Acriflavin resistance protein 0.68 Pf1N1B4_3947 ATP-dependent protease La (EC 3.4.21.53) Type I — —
Pseudomonas putida KT2440 0.46 PP_0906 putative Multidrug efflux RND transporter 0.68 PP_2302 DNA-binding, ATP-dependent protease low > 96
Pseudomonas sp. SVBP6 0.46 COO64_RS12055 multidrug efflux RND transporter permease subunit 0.67 COO64_RS19205 lon endopeptidase La low > 93
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_04000 acriflavine resistance protein B 0.68 AO353_20185 DNA-binding protein low > 101
Pseudomonas aeruginosa PUPa3 0.46 DQ20_RS57065 mexW;inference=COORDINATES multidrug efflux RND transporter permease subunit MexW 0.70 DQ20_RS54820 lon;go_function=ATP-dependent endopeptidase La low > 101
Pseudomonas aeruginosa PA14 0.46 IKLFDK_02225 multidrug efflux RND transporter permease subunit MexW 0.70 IKLFDK_08760 endopeptidase La low > 98
Pseudomonas aeruginosa MRSN321 0.46 DY961_RS24615 mexW;inference=COORDINATES multidrug efflux RND transporter permease subunit MexW 0.70 DY961_RS20740 lon;go_function=ATP-dependent endopeptidase La low > 100
Pseudomonas sp. DMC3 0.46 GFF5069 Multidrug efflux pump subunit AcrB 0.68 GFF1445 Lon protease low > 89
Marinobacter adhaerens HP15 0.46 HP15_3262 multidrug resistance protein 0.67 HP15_2183 DNA-binding ATP-dependent protease La low > 73
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_1771 RND multidrug efflux transporter; Acriflavin resistance protein 0.69 PfGW456L13_2554 ATP-dependent protease La (EC 3.4.21.53) Type I low > 87
Pseudomonas stutzeri RCH2 0.45 Psest_1153 Cation/multidrug efflux pump 0.69 Psest_2285 ATP-dependent protease La low > 67
Variovorax sp. SCN45 0.45 GFF3509 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) => MexI of MexHI-OpmD system 0.64 GFF487 ATP-dependent protease La (EC 3.4.21.53) Type I low > 127
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS26025 efflux RND transporter permease subunit 0.68 QEN71_RS21975 endopeptidase La low > 153
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS29560 acriflavine resistance protein B 0.68 BPHYT_RS09460 peptidase — —
Xanthobacter sp. DMC5 0.40 GFF2738 Efflux pump membrane transporter BepE 0.63 GFF1156 Lon protease — —
Dechlorosoma suillum PS 0.35 Dsui_1555 cation/multidrug efflux pump 0.67 Dsui_2198 ATP-dependent protease La low > 51
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF4261 RND multidrug efflux transporter; Acriflavin resistance protein 0.66 GFF4044 ATP-dependent protease La (EC 3.4.21.53) Type I low > 90
Acidovorax sp. GW101-3H11 0.34 Ac3H11_482 RND multidrug efflux transporter; Acriflavin resistance protein 0.66 Ac3H11_937 ATP-dependent protease La (EC 3.4.21.53) Type I low > 79
Desulfovibrio vulgaris Hildenborough JW710 0.25 DVU0061 multidrug resistance protein, putative (TIGR) 0.54 DVU1337 lon ATP-dependent protease La (TIGR) 0.38 23
Acinetobacter baumannii LAC-4 0.25 RR41_RS03865 multidrug efflux RND transporter permease subunit AdeJ 0.53 RR41_RS09075 endopeptidase La — —
Acinetobacter radioresistens SK82 0.24 MPMX26_00689 Multidrug resistance protein MexB 0.53 MPMX26_02299 Lon protease low > 36
Methylophilus sp. DMC18 0.24 GFF1649 Efflux pump membrane transporter BepE 0.68 GFF1305 Lon protease low > 43
Enterobacter asburiae PDN3 0.24 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family 0.83 EX28DRAFT_2531 endopeptidase La low > 76
Klebsiella michiganensis M5al 0.24 BWI76_RS06775 multidrug efflux RND transporter permease subunit 0.83 BWI76_RS06535 endopeptidase La low > 92
Escherichia coli BW25113 0.24 b2470 acrD aminoglycoside/multidrug efflux system (NCBI) 0.82 b0439 lon DNA-binding ATP-dependent protease La (NCBI) low > 76
Escherichia coli ECOR38 0.24 HEPCGN_21140 acrD multidrug efflux RND transporter permease AcrD 0.82 HEPCGN_06935 lon_P403L Lon protease low > 88
Escherichia coli ECRC62 0.24 BNILDI_12460 acrD multidrug efflux RND transporter permease AcrD 0.82 BNILDI_22670 lon_P403L Lon protease low > 75
Escherichia fergusonii Becca 0.24 EFB2_01418 Multidrug efflux pump subunit AcrB 0.82 EFB2_03618 Lon protease low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF4246 RND efflux system, inner membrane transporter CmeB 0.82 GFF4355 ATP-dependent protease La (EC 3.4.21.53) Type I low > 78
Escherichia coli BL21 0.24 ECD_02361 aminoglycoside/multidrug efflux system 0.82 ECD_00391 DNA-binding ATP-dependent protease La low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_01261 Multidrug efflux pump subunit AcrB 0.82 OHPLBJKB_03234 Lon protease low > 74
Escherichia coli ECOR27 0.24 NOLOHH_13650 acrD multidrug efflux RND transporter permease AcrD 0.82 NOLOHH_01255 lon_P403L Lon protease low > 76
Enterobacter sp. TBS_079 0.24 MPMX20_01064 Multidrug efflux pump subunit AcrB 0.83 MPMX20_01030 Lon protease low > 85
Escherichia coli ECRC99 0.24 KEDOAH_06250 acrD multidrug efflux RND transporter permease AcrD 0.82 KEDOAH_19645 Lon protease — —
Escherichia coli ECRC101 0.24 MCAODC_12500 acrD multidrug efflux RND transporter permease AcrD 0.82 MCAODC_27545 Lon protease low > 87
Escherichia coli ECRC98 0.24 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD 0.82 JDDGAC_11975 Lon protease low > 87
Escherichia coli ECRC100 0.24 OKFHMN_21970 acrD multidrug efflux RND transporter permease AcrD 0.82 OKFHMN_08320 Lon protease low > 79
Escherichia coli ECRC102 0.24 NIAGMN_19740 acrD multidrug efflux RND transporter permease AcrD 0.82 NIAGMN_06375 Lon protease — —
Escherichia coli Nissle 1917 0.24 ECOLIN_RS14090 multidrug efflux RND transporter permease AcrD 0.82 ECOLIN_RS02635 endopeptidase La low > 55
Klebsiella pneumoniae MKP103 0.24 KDGMDA_14835 acriflavine resistance protein B 0.83 KDGMDA_14620 Lon protease low > 95
Paraburkholderia graminis OAS925 0.24 ABIE53_005788 multidrug efflux pump 0.66 ABIE53_002117 ATP-dependent Lon protease low > 113
Pseudomonas orientalis W4I3 0.24 QF045_RS16760 efflux RND transporter permease subunit 0.69 QF045_RS18890 endopeptidase La low > 93
Desulfovibrio vulgaris Miyazaki F 0.24 DvMF_2163 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family (RefSeq) 0.54 DvMF_0112 ATP-dependent protease La (RefSeq) low > 51
Pseudomonas syringae pv. syringae B728a ΔmexB 0.23 Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 0.68 Psyr_1749 ATP-dependent proteinase, Serine peptidase, MEROPS family S16 low > 86
Pseudomonas syringae pv. syringae B728a 0.23 Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 0.68 Psyr_1749 ATP-dependent proteinase, Serine peptidase, MEROPS family S16 low > 86
Bosea sp. OAE506 0.23 ABIE41_RS01595 efflux RND transporter permease subunit 0.61 ABIE41_RS18050 endopeptidase La — —
Rhodanobacter sp. FW510-T8 0.23 OKGIIK_11990 acrB acriflavine resistance protein B 0.67 OKGIIK_08030 lon endopeptidase La 0.52 41
Caulobacter crescentus NA1000 Δfur 0.23 CCNA_00850 cation/multidrug efflux pump acrB2 0.62 CCNA_02037 ATP-dependent endopeptidase Lon — —
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS11745 efflux RND transporter permease subunit 0.66 ABZR86_RS07320 endopeptidase La low > 74
Caulobacter crescentus NA1000 0.23 CCNA_00850 cation/multidrug efflux pump acrB2 0.62 CCNA_02037 ATP-dependent endopeptidase Lon low > 66
Pseudomonas lactucae CFBP13502 0.23 GEMAOFIL_03223 multidrug efflux RND transporter permease subunit OqxB9 0.69 GEMAOFIL_03741 Lon protease low > 96
Rahnella sp. WP5 0.23 EX31_RS22470 multidrug efflux RND transporter permease subunit 0.82 EX31_RS22255 endopeptidase La low > 89
Serratia liquefaciens MT49 0.23 IAI46_18690 multidrug efflux RND transporter permease AcrD 0.83 IAI46_05020 endopeptidase La low > 87
Herbaspirillum seropedicae SmR1 0.23 HSERO_RS23055 multidrug transporter 0.68 HSERO_RS12905 peptidase — —
Rhodanobacter denitrificans MT42 0.23 LRK55_RS11630 efflux RND transporter permease subunit 0.67 LRK55_RS16460 endopeptidase La low > 63
Cellulophaga baltica 18 0.23 M666_RS00650 efflux RND transporter permease subunit 0.40 M666_RS11425 endopeptidase La low > 67
Rhodanobacter denitrificans FW104-10B01 0.23 LRK54_RS11905 efflux RND transporter permease subunit 0.67 LRK54_RS16735 endopeptidase La low > 59
Pantoea agglomerans CFBP13505 P0401 0.23 PagCFBP13505_RS19855 multidrug efflux RND transporter permease AcrD 0.83 PagCFBP13505_RS10550 endopeptidase La — —
Pectobacterium carotovorum WPP14 0.23 HER17_RS01560 multidrug efflux RND transporter permease AcrD 0.84 HER17_RS15840 endopeptidase La — —
Paraburkholderia bryophila 376MFSha3.1 0.23 H281DRAFT_04170 multidrug efflux pump 0.67 H281DRAFT_00898 ATP-dependent proteinase. Serine peptidase. MEROPS family S16 — —
Kangiella aquimarina DSM 16071 0.23 B158DRAFT_0733 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family 0.69 B158DRAFT_1038 ATP-dependent protease La low > 40
Dickeya dadantii 3937 0.23 DDA3937_RS05735 multidrug efflux RND transporter permease subunit 0.84 DDA3937_RS05650 endopeptidase La low > 74
Pantoea sp. MT58 0.23 IAI47_05310 multidrug efflux RND transporter permease AcrD 0.83 IAI47_14645 endopeptidase La — —
Erwinia amylovora T8 0.22 OLJFJH_17855 multidrug efflux RND transporter permease subunit AcrB 0.83 OLJFJH_17960 endopeptidase La low > 58
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS09795 efflux RND transporter permease subunit 0.69 ABZR87_RS12785 endopeptidase La low > 80
Variovorax sp. OAS795 0.22 ABID97_RS17350 efflux RND transporter permease subunit 0.66 ABID97_RS17590 endopeptidase La low > 91
Dickeya dianthicola ME23 0.22 DZA65_RS06115 multidrug efflux RND transporter permease subunit 0.83 DZA65_RS06020 endopeptidase La low > 75
Dickeya dianthicola 67-19 0.22 HGI48_RS05790 multidrug efflux RND transporter permease subunit 0.83 HGI48_RS05695 endopeptidase La 0.54 56
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS32420 multidrug efflux RND transporter permease subunit 0.67 RR42_RS09030 DNA-binding protein — —
Ralstonia solanacearum GMI1000 0.22 RS_RS00045 multidrug efflux RND transporter permease subunit 0.69 RS_RS08655 endopeptidase La — —
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS09445 multidrug efflux RND transporter permease subunit 0.69 RALBFv3_RS01340 endopeptidase La — —
Ralstonia solanacearum UW163 0.22 UW163_RS04135 multidrug efflux RND transporter permease subunit 0.69 UW163_RS14650 endopeptidase La — —
Ralstonia solanacearum PSI07 0.22 RPSI07_RS23905 hydrophobe/amphiphile efflux-1 family RND transporter 0.69 RPSI07_RS16135 endopeptidase La — —
Rhodanobacter sp000427505 FW510-R12 0.22 LRK53_RS07935 multidrug efflux RND transporter permease subunit 0.67 LRK53_RS12135 endopeptidase La low > 59
Erwinia tracheiphila SCR3 0.22 LU632_RS18185 efflux RND transporter permease subunit 0.83 LU632_RS18335 lon endopeptidase La — —
Erwinia tracheiphila HP pepo 2.2 0.21 IJEDHG_16580 adeB hydrophobe/amphiphile efflux-1 family RND transporter 0.83 IJEDHG_16450 lon endopeptidase La — —
Castellaniella sp019104865 MT123 0.20 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.67 ABCV34_RS05125 endopeptidase La — —

Not shown: 1 genomes with orthologs for CSW01_00850 only; 23 genomes with orthologs for CSW01_09605 only