Conservation of cofitness between CSW01_18760 and CSW01_07490 in Vibrio cholerae E7946 ATCC 55056

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_18760 dihydroorotase 1.0 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.76 5
Shewanella sp. ANA-3 0.77 Shewana3_3263 dihydroorotase (RefSeq) 0.65 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.97 1
Shewanella amazonensis SB2B 0.77 Sama_2870 dihydroorotase (RefSeq) 0.64 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.92 2
Shewanella oneidensis MR-1 0.75 SO3695 pyrC dihydroorotase, homodimeric type (NCBI ptt file) 0.63 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.98 1
Shewanella loihica PV-4 0.74 Shew_0728 dihydroorotase (RefSeq) 0.64 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.97 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.67 Psyr_3894 dihydroorotase 0.56 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a 0.67 Psyr_3894 dihydroorotase 0.56 Psyr_2106 dihydroorotate oxidase A — —
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_1241 dihydroorotase (EC 3.5.2.3) 0.55 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N1B4 0.67 Pf1N1B4_744 Dihydroorotase (EC 3.5.2.3) 0.58 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens GW456-L13 0.67 PfGW456L13_1747 Dihydroorotase (EC 3.5.2.3) 0.58 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_04115 dihydroorotase 0.58 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. DMC3 0.67 GFF5094 Dihydroorotase 0.58 GFF5252 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. SVBP6 0.67 COO64_RS16860 pyrC dihydroorotase 0.55 COO64_RS05305 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas sp. RS175 0.67 PFR28_03355 Dihydroorotase 0.57 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas segetis P6 0.67 MPMX49_01445 Dihydroorotase 0.57 MPMX49_03027 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2C3 0.66 AO356_18315 dihydroorotase 0.57 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas putida KT2440 0.66 PP_1086 dihydroorotase 0.56 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas simiae WCS417 0.66 PS417_05630 dihydroorotase 0.57 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.66 PFLU_RS05715 dihydroorotase 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas sp. BP01 0.66 JOY50_RS14925 pyrC dihydroorotase 0.56 JOY50_RS22105 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.66 PFLU_RS05715 dihydroorotase 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas aeruginosa PA14 0.66 IKLFDK_18005 dihydroorotase 0.55 IKLFDK_15515 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas stutzeri RCH2 0.66 Psest_3123 dihydroorotase, homodimeric type 0.54 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.91 1
Pseudomonas fluorescens FW300-N2E2 0.66 Pf6N2E2_5588 Dihydroorotase (EC 3.5.2.3) 0.57 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas lactucae CFBP13502 0.66 GEMAOFIL_01313 Dihydroorotase 0.57 GEMAOFIL_04332 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. S08-1 0.66 OH686_03940 dihydroorotase, homodimeric type 0.56 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Ralstonia solanacearum GMI1000 0.65 RS_RS02420 dihydroorotase 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Marinobacter adhaerens HP15 0.65 HP15_1216 dihydroorotase, homodimeric type 0.49 HP15_1377 dihydroorotate dehydrogenase 0.78 1
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS07550 dihydroorotase 0.53 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.64 RPSI07_RS21625 dihydroorotase 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.64 UW163_RS01995 dihydroorotase 0.53 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.64 RALBFv3_RS11590 dihydroorotase 0.53 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.62 HSERO_RS19235 dihydroorotase 0.52 HSERO_RS16155 dihydroorotate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS02610 dihydroorotase 0.51 RR42_RS07465 dihydroorotate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.62 Ac3H11_1963 Dihydroorotase (EC 3.5.2.3) 0.50 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Paraburkholderia graminis OAS925 0.62 ABIE53_003505 dihydroorotase 0.56 ABIE53_001954 dihydroorotate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.61 H281DRAFT_04265 dihydroorotase 0.56 H281DRAFT_00743 dihydroorotate oxidase A — —
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS26855 dihydroorotase 0.58 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.61 BPHYT_RS16675 dihydroorotase 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase 0.82 4
Methylophilus sp. DMC18 0.61 GFF2451 Dihydroorotase 0.57 GFF2704 Dihydroorotate dehydrogenase (quinone) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.61 GFF523 Dihydroorotase (EC 3.5.2.3) 0.49 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.98 1
Alteromonas macleodii MIT1002 0.61 MIT1002_03750 Dihydroorotase 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) — —
Dechlorosoma suillum PS 0.60 Dsui_0250 dihydroorotase, homodimeric type 0.58 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Rhodanobacter sp000427505 FW510-R12 0.59 LRK53_RS03690 dihydroorotase 0.49 LRK53_RS12795 quinone-dependent dihydroorotate dehydrogenase — —
Acinetobacter radioresistens SK82 0.59 MPMX26_02262 Dihydroorotase 0.54 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) — —
Acinetobacter baumannii LAC-4 0.59 RR41_RS09355 dihydroorotase 0.54 RR41_RS06340 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. OAS795 0.59 ABID97_RS06040 dihydroorotase 0.49 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.59 GFF4557 Dihydroorotase (EC 3.5.2.3) 0.50 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Rhodanobacter denitrificans FW104-10B01 0.59 LRK54_RS10900 dihydroorotase 0.50 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.57 LRK55_RS10600 dihydroorotase 0.51 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.57 OKGIIK_12970 pyrC dihydroorotase 0.50 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Synechocystis sp000284455 PCC 6803 0.57 SGL_RS12080 dihydroorotase 0.35 SGL_RS17005 quinone-dependent dihydroorotate dehydrogenase — —
Castellaniella sp019104865 MT123 0.57 ABCV34_RS09730 dihydroorotase 0.49 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Erwinia tracheiphila SCR3 0.57 LU632_RS10340 pyrC dihydroorotase 0.73 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 3
Erwinia tracheiphila HP pepo 2.2 0.57 IJEDHG_20990 pyrC dihydroorotase 0.73 IJEDHG_20465 pyrD quinone-dependent dihydroorotate dehydrogenase 0.91 6
Serratia liquefaciens MT49 0.57 IAI46_09740 dihydroorotase 0.72 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.80 17
Enterobacter asburiae PDN3 0.57 EX28DRAFT_1869 dihydroorotase (EC 3.5.2.3) 0.73 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Enterobacter sp. TBS_079 0.57 MPMX20_01741 Dihydroorotase 0.73 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.97 1
Erwinia amylovora T8 0.56 OLJFJH_15670 dihydroorotase 0.74 OLJFJH_15990 quinone-dependent dihydroorotate dehydrogenase 0.90 1
Klebsiella pneumoniae MKP103 0.56 KDGMDA_18610 dihydroorotase 0.72 KDGMDA_18145 quinone-dependent dihydroorotate dehydrogenase 0.22 58
Dickeya dadantii 3937 0.56 DDA3937_RS13170 dihydroorotase 0.71 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.94 1
Pectobacterium carotovorum WPP14 0.56 HER17_RS08600 dihydroorotase 0.72 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.98 5
Dickeya dianthicola ME23 0.55 DZA65_RS13710 dihydroorotase 0.71 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.96 1
Klebsiella michiganensis M5al 0.55 BWI76_RS10990 dihydroorotase 0.71 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.88 1
Rahnella sp. WP5 0.55 EX31_RS24385 dihydroorotase 0.72 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.94 3
Escherichia coli ECRC100 0.55 OKFHMN_03730 pyrC dihydroorotase 0.72 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.85 32
Escherichia coli ECRC98 0.55 JDDGAC_07390 pyrC dihydroorotase 0.72 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia coli ECRC101 0.55 MCAODC_23090 pyrC dihydroorotase 0.72 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.93 1
Escherichia coli ECRC102 0.55 NIAGMN_24100 pyrC dihydroorotase 0.72 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.82 9
Escherichia coli ECRC62 0.55 BNILDI_19420 pyrC dihydroorotase 0.72 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.97 4
Escherichia coli BL21 0.55 ECD_01058 dihydro-orotase 0.72 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.74 13
Escherichia fergusonii Becca 0.55 EFB2_02912 Dihydroorotase 0.72 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECRC99 0.55 KEDOAH_24025 pyrC dihydroorotase 0.72 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_02603 Dihydroorotase 0.72 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.71 3
Escherichia coli ECOR27 0.55 NOLOHH_21260 pyrC dihydroorotase 0.72 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.93 10
Escherichia coli BW25113 0.55 b1062 pyrC dihydroorotase (NCBI) 0.72 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.97 1
Pantoea agglomerans CFBP13505 P0401 0.55 PagCFBP13505_RS05115 dihydroorotase 0.74 PagCFBP13505_RS04625 quinone-dependent dihydroorotate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.55 HGI48_RS13235 dihydroorotase 0.70 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.88 2
Escherichia coli ECOR38 0.55 HEPCGN_23760 pyrC dihydroorotase 0.72 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.90 20
Escherichia coli Nissle 1917 0.55 ECOLIN_RS06160 dihydroorotase 0.72 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Pantoea sp. MT58 0.54 IAI47_12215 dihydroorotase 0.74 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.98 1
Azospirillum sp. SherDot2 0.53 MPMX19_01633 Dihydroorotase 0.38 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Sinorhizobium meliloti 1021 0.53 SMc02166 dihydroorotase 0.42 SMc02245 dihydroorotate dehydrogenase 2 0.96 1
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.53 GFF3342 Dihydroorotase (EC 3.5.2.3) 0.71 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.79 1
Agrobacterium fabrum C58 0.53 Atu0399 dihydroorotase 0.41 Atu0486 dihydroorotate dehydrogenase 0.92 2
Azospirillum brasilense Sp245 0.52 AZOBR_RS04460 dihydroorotase 0.38 AZOBR_RS13520 dihydroorotate dehydrogenase 0.83 1
Rhizobium sp. OAE497 0.52 ABIE40_RS02105 dihydroorotase 0.40 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.52 PGA1_c10910 dihydroorotase PyrC 0.34 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.97 1
Dinoroseobacter shibae DFL-12 0.51 Dshi_2371 dihydroorotase, homodimeric type (RefSeq) 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.94 1

Not shown: 0 genomes with orthologs for CSW01_18760 only; 25 genomes with orthologs for CSW01_07490 only