Conservation of cofitness between CSW01_12405 and CSW01_05930 in Vibrio cholerae E7946 ATCC 55056

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12405 GTP diphosphokinase 1.0 CSW01_05930 tryptophan synthase subunit beta 0.46 8
Dickeya dianthicola 67-19 0.67 HGI48_RS17070 GTP diphosphokinase 0.85 HGI48_RS10465 tryptophan synthase subunit beta low > 71
Dickeya dadantii 3937 0.67 DDA3937_RS17015 GTP diphosphokinase 0.85 DDA3937_RS10465 tryptophan synthase subunit beta low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.67 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 0.83 GFF2725 Tryptophan synthase beta chain (EC 4.2.1.20) low > 78
Dickeya dianthicola ME23 0.67 DZA65_RS18145 GTP diphosphokinase 0.85 DZA65_RS10945 tryptophan synthase subunit beta low > 75
Klebsiella pneumoniae MKP103 0.67 KDGMDA_03335 GTP diphosphokinase 0.83 KDGMDA_19550 tryptophan synthase subunit beta low > 95
Escherichia coli ECRC99 0.67 KEDOAH_07880 relA GTP diphosphokinase 0.82 KEDOAH_26080 trpB tryptophan synthase subunit beta
Escherichia coli BL21 0.67 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase 0.82 ECD_01235 tryptophan synthase, beta subunit low > 61
Escherichia coli ECOR38 0.67 HEPCGN_19500 relA GTP diphosphokinase 0.82 HEPCGN_25520 trpB tryptophan synthase subunit beta 0.46 76
Escherichia coli ECRC101 0.67 MCAODC_10775 relA GTP diphosphokinase 0.82 MCAODC_15595 trpB tryptophan synthase subunit beta low > 88
Escherichia coli ECOR27 0.67 NOLOHH_12125 relA GTP diphosphokinase 0.82 NOLOHH_20330 trpB tryptophan synthase subunit beta low > 76
Escherichia coli ECRC98 0.67 JDDGAC_23915 relA GTP diphosphokinase 0.82 JDDGAC_05215 trpB tryptophan synthase subunit beta 0.35 85
Escherichia coli ECRC62 0.67 BNILDI_10630 relA GTP diphosphokinase 0.82 BNILDI_18475 trpB tryptophan synthase subunit beta 0.50 56
Escherichia coli ECRC100 0.67 OKFHMN_20250 relA GTP diphosphokinase 0.82 OKFHMN_02670 trpB tryptophan synthase subunit beta low > 79
Escherichia coli Nissle 1917 0.67 ECOLIN_RS15515 GTP diphosphokinase 0.82 ECOLIN_RS07600 tryptophan synthase subunit beta low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_00947 GTP pyrophosphokinase 0.82 OHPLBJKB_02422 Tryptophan synthase beta chain low > 74
Escherichia coli BW25113 0.67 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) 0.82 b1261 trpB tryptophan synthase subunit beta (NCBI) 0.49 53
Escherichia coli ECRC102 0.67 NIAGMN_18020 relA GTP diphosphokinase 0.82 NIAGMN_26840 trpB tryptophan synthase subunit beta
Escherichia fergusonii Becca 0.67 EFB2_01133 GTP pyrophosphokinase 0.82 EFB2_02665 Tryptophan synthase beta chain low > 86
Klebsiella michiganensis M5al 0.67 BWI76_RS22805 GTP diphosphokinase 0.83 BWI76_RS11845 tryptophan synthase subunit beta 0.57 20
Enterobacter sp. TBS_079 0.66 MPMX20_03653 GTP pyrophosphokinase 0.83 MPMX20_02513 Tryptophan synthase beta chain 0.58 19
Pantoea sp. MT58 0.66 IAI47_04120 GTP diphosphokinase 0.84 IAI47_09170 tryptophan synthase subunit beta low > 76
Enterobacter asburiae PDN3 0.66 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family 0.82 EX28DRAFT_0933 tryptophan synthase, beta subunit low > 76
Erwinia tracheiphila HP pepo 2.2 0.66 IJEDHG_17375 relA GTP diphosphokinase 0.82 IJEDHG_23490 trpB tryptophan synthase subunit beta 0.83 36
Erwinia tracheiphila SCR3 0.66 LU632_RS06350 relA GTP diphosphokinase 0.83 LU632_RS12770 trpB tryptophan synthase subunit beta low > 74
Erwinia amylovora T8 0.66 OLJFJH_09245 GTP diphosphokinase 0.84 OLJFJH_13475 tryptophan synthase subunit beta low > 58
Pantoea agglomerans CFBP13505 P0401 0.66 PagCFBP13505_RS16850 GTP diphosphokinase 0.84 PagCFBP13505_RS07015 tryptophan synthase subunit beta low > 74
Rahnella sp. WP5 0.66 EX31_RS07955 GTP diphosphokinase 0.82 EX31_RS09975 tryptophan synthase subunit beta 0.87 28
Pectobacterium carotovorum WPP14 0.66 HER17_RS04115 GTP diphosphokinase 0.85 HER17_RS10935 tryptophan synthase subunit beta low > 75
Serratia liquefaciens MT49 0.66 IAI46_03600 GTP diphosphokinase 0.84 IAI46_14040 tryptophan synthase subunit beta low > 86
Shewanella amazonensis SB2B 0.57 Sama_1033 GTP diphosphokinase (RefSeq) 0.81 Sama_2133 tryptophan synthase subunit beta (RefSeq) 0.91 23
Shewanella sp. ANA-3 0.56 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.82 Shewana3_1516 tryptophan synthase subunit beta (RefSeq) 0.89 3
Shewanella oneidensis MR-1 0.56 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) 0.82 SO3023 trpB tryptophan synthase, beta subunit (NCBI ptt file) 0.91 34
Shewanella loihica PV-4 0.56 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.82 Shew_2255 tryptophan synthase subunit beta (RefSeq) 0.92 2
Alteromonas macleodii MIT1002 0.53 MIT1002_00794 GTP pyrophosphokinase 0.74 MIT1002_01426 Tryptophan synthase beta chain
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.53 PfGW456L13_566 Tryptophan synthase beta chain (EC 4.2.1.20) low > 87
Pseudomonas syringae pv. syringae B728a 0.45 Psyr_3695 RelA/SpoT protein 0.52 Psyr_0034 tryptophan synthase, beta chain 0.46 19
Pseudomonas syringae pv. syringae B728a ΔmexB 0.45 Psyr_3695 RelA/SpoT protein 0.52 Psyr_0034 tryptophan synthase, beta chain low > 86
Pseudomonas fluorescens FW300-N2C3 0.45 AO356_19060 (p)ppGpp synthetase 0.53 AO356_10915 tryptophan synthase subunit beta 0.44 19
Pseudomonas lactucae CFBP13502 0.45 GEMAOFIL_04223 GTP pyrophosphokinase 0.53 GEMAOFIL_00242 Tryptophan synthase beta chain low > 93
Pseudomonas sp. RS175 0.45 PFR28_03223 GTP pyrophosphokinase 0.54 PFR28_04715 Tryptophan synthase beta chain
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.53 Pf6N2E2_4048 Tryptophan synthase beta chain (EC 4.2.1.20) 0.35 23
Pseudomonas fluorescens FW300-N2E3 0.45 AO353_02710 (p)ppGpp synthetase 0.53 AO353_10710 tryptophan synthase subunit beta 0.48 52
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS22095 GTP diphosphokinase 0.54 PFLU_RS00180 tryptophan synthase subunit beta low > 109
Pseudomonas fluorescens SBW25 0.45 PFLU_RS22095 GTP diphosphokinase 0.54 PFLU_RS00180 tryptophan synthase subunit beta low > 109
Pseudomonas simiae WCS417 0.45 PS417_20150 (p)ppGpp synthetase 0.54 PS417_00185 tryptophan synthase subunit beta
Pseudomonas fluorescens FW300-N1B4 0.45 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.54 Pf1N1B4_1831 Tryptophan synthase beta chain (EC 4.2.1.20) low > 87
Pseudomonas sp. DMC3 0.45 GFF4818 GTP pyrophosphokinase 0.53 GFF676 Tryptophan synthase beta chain low > 89
Pseudomonas putida KT2440 0.45 PP_1656 ATP:GTP 3'-pyrophosphotransferase 0.54 PP_0083 tryptophan synthase beta chain 0.50 8
Pseudomonas sp. BP01 0.45 JOY50_RS23910 relA GTP diphosphokinase 0.54 JOY50_RS21310 trpB tryptophan synthase subunit beta low > 84
Pseudomonas sp. SVBP6 0.45 COO64_RS07325 relA GTP diphosphokinase 0.52 COO64_RS02275 trpB tryptophan synthase subunit beta low > 93
Pseudomonas aeruginosa PA14 0.45 IKLFDK_04200 GTP diphosphokinase 0.53 IKLFDK_25375 tryptophan synthase subunit beta low > 100
Pseudomonas sp. S08-1 0.45 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I 0.53 OH686_12425 tryptophan synthase, beta subunit low > 80
Pseudomonas stutzeri RCH2 0.44 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family 0.53 Psest_0063 tryptophan synthase, beta subunit 0.31 62
Pseudomonas segetis P6 0.44 MPMX49_01654 GTP pyrophosphokinase 0.53 MPMX49_00373 Tryptophan synthase beta chain
Marinobacter adhaerens HP15 0.43 HP15_791 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA 0.55 HP15_1827 tryptophan synthase, beta subunit
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2277 (p)ppGpp synthetase, RelA/SpoT family 0.63 B158DRAFT_2429 tryptophan synthase, beta subunit low > 40
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.1489.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.51 Xcc-8004.1964.1 Tryptophan synthase beta chain (EC 4.2.1.20) low > 74
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS19725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.52 ABZR86_RS08000 tryptophan synthase subunit beta 0.47 31
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_02170 relA GTP diphosphokinase 0.52 OKGIIK_04845 trpB tryptophan synthase subunit beta low > 52
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS12725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.51 LRK54_RS01685 tryptophan synthase subunit beta low > 59
Rhodanobacter denitrificans MT42 0.38 LRK55_RS12430 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.51 LRK55_RS01465 tryptophan synthase subunit beta 0.90 4
Ralstonia solanacearum GMI1000 0.38 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.53 RS_RS09965 tryptophan synthase subunit beta low > 80
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.53 ABZR87_RS14500 tryptophan synthase subunit beta low > 80
Ralstonia solanacearum PSI07 0.38 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.53 RPSI07_RS14730 tryptophan synthase subunit beta low > 81
Rhodanobacter sp000427505 FW510-R12 0.38 LRK53_RS15870 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.51 LRK53_RS08350 tryptophan synthase subunit beta low > 59
Dechlorosoma suillum PS 0.38 Dsui_2816 (p)ppGpp synthetase, RelA/SpoT family 0.53 Dsui_3192 tryptophan synthase, beta subunit
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.53 RALBFv3_RS02585 tryptophan synthase subunit beta
Ralstonia solanacearum UW163 0.38 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.53 UW163_RS11140 tryptophan synthase subunit beta
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.54 QEN71_RS17645 tryptophan synthase subunit beta low > 153
Methylophilus sp. DMC18 0.37 GFF2658 GTP pyrophosphokinase 0.54 GFF656 Tryptophan synthase beta chain
Cupriavidus basilensis FW507-4G11 0.37 RR42_RS06585 GTP pyrophosphokinase 0.55 RR42_RS14360 tryptophan synthase subunit alpha low > 128
Lysobacter sp. OAE881 0.36 ABIE51_RS05170 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.52 ABIE51_RS08260 tryptophan synthase subunit beta low > 62
Paraburkholderia graminis OAS925 0.35 ABIE53_002905 GTP pyrophosphokinase 0.53 ABIE53_004809 tryptophan synthase beta chain
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04499 GTP pyrophosphokinase 0.53 H281DRAFT_06067 tryptophan synthase, beta chain low > 103
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS09855 GTP pyrophosphokinase 0.50 HSERO_RS16475 tryptophan synthase subunit alpha low > 78
Acinetobacter baumannii LAC-4 0.35 RR41_RS16080 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.53 RR41_RS03115 tryptophan synthase subunit beta low > 55
Acinetobacter radioresistens SK82 0.35 MPMX26_00539 GTP pyrophosphokinase 0.52 MPMX26_02617 Tryptophan synthase beta chain low > 36
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS13655 GTP pyrophosphokinase 0.54 BPHYT_RS33875 tryptophan synthase subunit alpha 0.17 103
Acidovorax sp. GW101-3H11 0.34 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.53 Ac3H11_1534 Tryptophan synthase beta chain (EC 4.2.1.20) 0.47 33
Castellaniella sp019104865 MT123 0.34 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.51 ABCV34_RS08435 tryptophan synthase subunit beta
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF4925 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.53 GFF3355 Tryptophan synthase beta chain (EC 4.2.1.20) 0.63 42
Variovorax sp. SCN45 0.32 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.53 GFF3883 Tryptophan synthase beta chain (EC 4.2.1.20)
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS17885 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.48 HMPREF1058_RS07170 tryptophan synthase subunit beta 0.55 37
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS14150 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.48 ABI39_RS21045 tryptophan synthase subunit beta low > 72
Bacteroides thetaiotaomicron VPI-5482 0.24 BT0700 GTP pyrophosphokinase (NCBI ptt file) 0.48 BT0533 tryptophan synthase beta chain (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.24 BACOVA_02404 RelA/SpoT family protein 0.47 BACOVA_03779 tryptophan synthase, beta subunit low > 96
Bacteroides stercoris CC31F 0.24 HMPREF1181_RS16240 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.47 HMPREF1181_RS15320 tryptophan synthase subunit beta low > 56

Not shown: 0 genomes with orthologs for CSW01_12405 only; 31 genomes with orthologs for CSW01_05930 only