Conservation of cofitness between BWI76_RS24910 and BWI76_RS26665 in Klebsiella michiganensis M5al

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS24910 rRNA (cytidine-2'-O-)-methyltransferase 1.0 BWI76_RS26665 DNA-binding response regulator 0.33 7
Escherichia coli ECRC101 0.90 MCAODC_08755 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 MCAODC_07565 ompR_G63V two-component system response regulator OmpR low > 87
Escherichia coli ECRC98 0.90 JDDGAC_21860 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 JDDGAC_20665 ompR_G63V two-component system response regulator OmpR low > 86
Escherichia coli ECRC100 0.90 OKFHMN_18235 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 OKFHMN_17035 ompR_G63V two-component system response regulator OmpR low > 80
Escherichia coli BW25113 0.90 b3146 yraL predicted methyltransferase (NCBI) 1.00 b3405 ompR osmolarity response regulator (NCBI) low > 76
Escherichia coli ECRC102 0.90 NIAGMN_15995 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 NIAGMN_14805 ompR_G63V two-component system response regulator OmpR — —
Escherichia coli BL21 0.90 ECD_03013 16S rRNA C1402 2'-O-ribose methyltransferase, SAM-dependent 1.00 ECD_03257 response regulator in two-component regulatory system with EnvZ low > 61
Escherichia coli ECRC99 0.90 KEDOAH_09915 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 KEDOAH_11105 ompR_G63V two-component system response regulator OmpR — —
Escherichia coli ECOR38 0.90 HEPCGN_17110 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 HEPCGN_15845 ompR_G63V two-component system response regulator OmpR low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.90 OHPLBJKB_00555 Ribosomal RNA small subunit methyltransferase I 1.00 OHPLBJKB_00298 Transcriptional regulatory protein OmpR low > 73
Escherichia fergusonii Becca 0.90 EFB2_00677 Ribosomal RNA small subunit methyltransferase I 1.00 EFB2_00423 Transcriptional regulatory protein OmpR low > 86
Escherichia coli Nissle 1917 0.90 ECOLIN_RS18085 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 ECOLIN_RS19455 two-component system response regulator OmpR low > 55
Escherichia coli ECRC62 0.89 BNILDI_01495 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 BNILDI_02695 ompR_G63V two-component system response regulator OmpR low > 75
Escherichia coli ECOR27 0.89 NOLOHH_10035 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 NOLOHH_08825 ompR_G63V two-component system response regulator OmpR low > 75
Enterobacter asburiae PDN3 0.88 EX28DRAFT_3195 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 EX28DRAFT_4138 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain low > 76
Enterobacter sp. TBS_079 0.88 MPMX20_04050 Ribosomal RNA small subunit methyltransferase I 1.00 MPMX20_04292 Transcriptional regulatory protein OmpR low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF1521 rRNA small subunit methyltransferase I 1.00 GFF613 Two-component system response regulator OmpR low > 78
Erwinia tracheiphila SCR3 0.80 LU632_RS02230 rsmI 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 LU632_RS22940 ompR two-component system response regulator OmpR low > 74
Pectobacterium carotovorum WPP14 0.80 HER17_RS19860 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 HER17_RS01700 two-component system response regulator OmpR low > 75
Rahnella sp. WP5 0.78 EX31_RS12550 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.99 EX31_RS04800 two-component system response regulator OmpR low > 89
Dickeya dianthicola 67-19 0.77 HGI48_RS01610 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 HGI48_RS19750 two-component system response regulator OmpR low > 71
Dickeya dadantii 3937 0.77 DDA3937_RS01715 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 DDA3937_RS19620 two-component system response regulator OmpR low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS01685 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 DZA65_RS20840 two-component system response regulator OmpR low > 75
Serratia liquefaciens MT49 0.76 IAI46_22295 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 IAI46_23790 two-component system response regulator OmpR 0.54 78
Pantoea sp. MT58 0.75 IAI47_02850 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1.00 IAI47_01820 two-component system response regulator OmpR low > 76
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_03090 rRNA (cytidine-2'-O-)-methyltransferase 0.85 CSW01_13695 two-component system response regulator OmpR low > 62
Shewanella loihica PV-4 0.60 Shew_0228 uroporphyrin-III C/tetrapyrrole methyltransferase (RefSeq) 0.82 Shew_3637 ompR osmolarity response regulator (RefSeq) low > 60
Shewanella amazonensis SB2B 0.60 Sama_3353 hypothetical protein (RefSeq) 0.83 Sama_3510 ompR osmolarity response regulator (RefSeq) low > 62
Shewanella oneidensis MR-1 0.58 SO0301 hypothetical methyltransferase (NCBI ptt file) 0.82 SO4633 ompR transcriptional regulatory protein OmpR (NCBI ptt file) low > 76
Pseudomonas stutzeri RCH2 0.57 Psest_3270 probable S-adenosylmethionine-dependent methyltransferase, YraL family 0.69 Psest_3995 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain low > 67
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_5346 rRNA small subunit methyltransferase I 0.69 Pf6N2E2_3905 Two-component system response regulator OmpR — —
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_17110 methyltransferase 0.69 AO356_10170 chemotaxis protein CheY 0.40 44
Shewanella sp. ANA-3 0.56 Shewana3_3879 hypothetical protein (RefSeq) 0.82 Shewana3_4017 ompR osmolarity response regulator (RefSeq) low > 73
Pseudomonas simiae WCS417 0.56 PS417_04590 methyltransferase 0.69 PS417_01170 chemotaxis protein CheY — —
Pseudomonas fluorescens SBW25 0.56 PFLU_RS04655 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.69 PFLU_RS01280 two-component system response regulator OmpR — —
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS04655 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.69 PFLU_RS01280 two-component system response regulator OmpR — —
Pseudomonas sp. RS175 0.56 PFR28_03597 Ribosomal RNA small subunit methyltransferase I 0.68 PFR28_04868 Transcriptional regulatory protein OmpR low > 88
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_15290 methyltransferase 0.69 AO353_11745 chemotaxis protein CheY — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.55 Psyr_4112 Protein of unknown function UPF0011 0.70 Psyr_0258 Two-component response regulator OmpR — —
Pseudomonas syringae pv. syringae B728a 0.55 Psyr_4112 Protein of unknown function UPF0011 0.70 Psyr_0258 Two-component response regulator OmpR — —
Pseudomonas fluorescens FW300-N1B4 0.55 Pf1N1B4_953 rRNA small subunit methyltransferase I 0.69 Pf1N1B4_1772 Two-component system response regulator OmpR — —
Pseudomonas sp. S08-1 0.54 OH686_08340 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.72 OH686_11095 Two-component system response regulator OmpR low > 80
Pseudomonas putida KT2440 0.54 PP_1326 16S rRNA 2'-O-ribose C1402 methyltransferase 0.70 PP_0246 two-component system DNA-binding response transcriptional dual regulator low > 96
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_1643 rRNA small subunit methyltransferase I 0.68 PfGW456L13_427 Two-component system response regulator OmpR low > 87
Marinobacter adhaerens HP15 0.53 HP15_554 tetrapyrrole methylase family protein 0.41 HP15_3961 two-component transcriptional regulator, winged helix family low > 73
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4371.1 rRNA small subunit methyltransferase I 0.38 Xcc-8004.974.1 two-component system regulatory protein low > 74
Lysobacter sp. OAE881 0.48 ABIE51_RS04695 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.40 ABIE51_RS14390 response regulator low > 62
Dechlorosoma suillum PS 0.48 Dsui_0251 putative S-adenosylmethionine-dependent methyltransferase, YraL family 0.61 Dsui_2401 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain low > 51
Dyella japonica UNC79MFTsu3.2 0.48 ABZR86_RS11380 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.39 ABZR86_RS21025 response regulator transcription factor low > 74
Alteromonas macleodii MIT1002 0.47 MIT1002_03113 Ribosomal RNA small subunit methyltransferase I 0.83 MIT1002_03968 Transcriptional regulatory protein OmpR low > 70
Kangiella aquimarina DSM 16071 0.46 B158DRAFT_2109 probable S-adenosylmethionine-dependent methyltransferase, YraL family 0.81 B158DRAFT_0684 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain low > 40
Acinetobacter radioresistens SK82 0.46 MPMX26_02282 Ribosomal RNA small subunit methyltransferase I 0.70 MPMX26_02838 Transcriptional regulatory protein OmpR low > 36
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS23345 16S rRNA methyltransferase 0.60 HSERO_RS10760 chemotaxis protein CheY — —
Paraburkholderia sabiae LMG 24235 0.39 QEN71_RS00655 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.62 QEN71_RS22030 two-component system response regulator OmpR low > 153
Castellaniella sp019104865 MT123 0.38 ABCV34_RS14320 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.61 ABCV34_RS08585 two-component system response regulator OmpR — —
Cupriavidus basilensis FW507-4G11 0.38 RR42_RS19740 16S rRNA methyltransferase 0.62 RR42_RS07885 chemotaxis protein CheY low > 128
Sinorhizobium meliloti 1021 0.38 SMc00416 hypothetical protein 0.42 SM_b21561 two component response regulator protein low > 103
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS01940 16S rRNA methyltransferase 0.63 BPHYT_RS09315 chemotaxis protein CheY low > 109
Rhizobium sp. OAE497 0.37 ABIE40_RS01370 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.41 ABIE40_RS24305 response regulator low > 107
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_02152 16S rRNA (cytidine1402-2'-O)-methyltransferase 0.63 H281DRAFT_00886 two component transcriptional regulator, winged helix family low > 103
Paraburkholderia graminis OAS925 0.36 ABIE53_000470 16S rRNA (cytidine1402-2'-O)-methyltransferase 0.63 ABIE53_002101 two-component system phosphate regulon response regulator OmpR low > 113
Magnetospirillum magneticum AMB-1 0.35 AMB_RS22780 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.47 AMB_RS16915 DNA-binding response regulator low > 64
Variovorax sp. SCN45 0.35 GFF3735 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (EC 2.1.1.198) 0.64 GFF408 Two-component system response regulator OmpR low > 127
Variovorax sp. OAS795 0.35 ABID97_RS00285 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.64 ABID97_RS17265 two-component system response regulator OmpR low > 91
Dinoroseobacter shibae DFL-12 0.34 Dshi_2831 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase (RefSeq) 0.42 Dshi_4048 two component transcriptional regulator, winged helix family (RefSeq) — —
Ralstonia solanacearum IBSBF1503 0.34 RALBFv3_RS08495 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.62 RALBFv3_RS01415 two-component system response regulator OmpR low > 76
Ralstonia solanacearum UW163 0.34 UW163_RS05115 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.62 UW163_RS14725 two-component system response regulator OmpR — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4466 rRNA small subunit methyltransferase I 0.66 Ac3H11_343 Two-component system response regulator OmpR — —
Ralstonia solanacearum PSI07 0.33 RPSI07_RS08730 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.62 RPSI07_RS16070 two-component system response regulator OmpR low > 81
Bosea sp. OAE506 0.33 ABIE41_RS03315 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.47 ABIE41_RS08395 response regulator low > 77
Rhodopseudomonas palustris CGA009 0.33 TX73_001680 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.45 TX73_018505 response regulator low > 86
Ralstonia solanacearum GMI1000 0.33 RS_RS16360 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.62 RS_RS08305 two-component system response regulator OmpR — —
Azospirillum sp. SherDot2 0.33 MPMX19_02471 Ribosomal RNA small subunit methyltransferase I 0.46 MPMX19_00010 Transcriptional regulatory protein OmpR low > 112
Azospirillum brasilense Sp245 0.33 AZOBR_RS02155 16S rRNA methyltransferase 0.47 AZOBR_RS00555 chemotaxis protein CheY low > 97
Ralstonia sp. UNC404CL21Col 0.33 ABZR87_RS03815 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.62 ABZR87_RS13210 two-component system response regulator OmpR low > 80
Sphingomonas koreensis DSMZ 15582 0.33 Ga0059261_2755 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.45 Ga0059261_0871 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain low > 68
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF2715 rRNA small subunit methyltransferase I 0.64 GFF4930 Two-component system response regulator OmpR low > 90
Brevundimonas sp. GW460-12-10-14-LB2 0.31 A4249_RS13300 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 0.35 A4249_RS10315 response regulator transcription factor — —
Caulobacter crescentus NA1000 Δfur 0.30 CCNA_00143 ribosomal RNA small subunit methyltransferase I 0.37 CCNA_01240 two-component response regulator low > 67
Caulobacter crescentus NA1000 0.30 CCNA_00143 ribosomal RNA small subunit methyltransferase I 0.37 CCNA_01240 two-component response regulator low > 66
Phaeobacter inhibens DSM 17395 0.24 PGA1_c26730 probable S-adenosylmethionine-dependent methyltransferase, YraL family 0.39 PGA1_c34130 protein PetR — —

Not shown: 6 genomes with orthologs for BWI76_RS24910 only; 5 genomes with orthologs for BWI76_RS26665 only