Conservation of cofitness between BWI76_RS00865 and BWI76_RS26125 in Klebsiella michiganensis M5al

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00865 DNA-binding transcriptional regulator OxyR 1.0 BWI76_RS26125 carboxypeptidase/penicillin-binding protein 1A 0.26 20
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.98 GFF2347 Hydrogen peroxide-inducible genes activator 0.89 GFF623 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_4424 Transcriptional regulator 0.89 EX28DRAFT_4146 penicillin-binding protein, 1A family
Enterobacter sp. TBS_079 0.96 MPMX20_04519 Hydrogen peroxide-inducible genes activator 0.88 MPMX20_04284 Penicillin-binding protein 1A low > 85
Escherichia coli Nissle 1917 0.96 ECOLIN_RS22870 DNA-binding transcriptional regulator OxyR 0.88 ECOLIN_RS19395 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 55
Escherichia coli ECRC101 0.96 MCAODC_04065 oxyR DNA-binding transcriptional regulator OxyR 0.88 MCAODC_07610 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA 0.43 69
Escherichia coli HS(pFamp)R (ATCC 700891) 0.96 OHPLBJKB_04089 Hydrogen peroxide-inducible genes activator 0.88 OHPLBJKB_00307 Penicillin-binding protein 1A low > 73
Escherichia coli BL21 0.96 ECD_03846 oxidative and nitrosative stress transcriptional regulator 0.88 ECD_03248 penicillin-binding protein 1a, murein transglycosylase and transpeptidase low > 61
Escherichia coli ECRC62 0.96 BNILDI_05825 oxyR DNA-binding transcriptional regulator OxyR 0.88 BNILDI_02650 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Escherichia coli BW25113 0.96 b3961 oxyR DNA-binding transcriptional dual regulator (NCBI) 0.88 b3396 mrcA peptidoglycan synthetase; penicillin-binding protein 1A (VIMSS) low > 76
Escherichia coli ECOR38 0.96 HEPCGN_12210 oxyR DNA-binding transcriptional regulator OxyR 0.88 HEPCGN_15900 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 87
Escherichia coli ECRC102 0.96 NIAGMN_11315 oxyR DNA-binding transcriptional regulator OxyR 0.88 NIAGMN_14850 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA
Escherichia coli ECRC98 0.96 JDDGAC_17190 oxyR DNA-binding transcriptional regulator OxyR 0.88 JDDGAC_20710 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 86
Escherichia coli ECRC99 0.96 KEDOAH_14595 oxyR DNA-binding transcriptional regulator OxyR 0.88 KEDOAH_11060 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA
Escherichia coli ECOR27 0.96 NOLOHH_05700 oxyR DNA-binding transcriptional regulator OxyR 0.88 NOLOHH_08870 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Escherichia fergusonii Becca 0.96 EFB2_04651 Hydrogen peroxide-inducible genes activator 0.88 EFB2_00432 Penicillin-binding protein 1A low > 86
Escherichia coli ECRC100 0.96 OKFHMN_13565 oxyR DNA-binding transcriptional regulator OxyR 0.88 OKFHMN_17080 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 80
Pectobacterium carotovorum WPP14 0.90 HER17_RS00955 DNA-binding transcriptional regulator OxyR 0.78 HER17_RS01745 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Dickeya dianthicola ME23 0.89 DZA65_RS21450 DNA-binding transcriptional regulator OxyR 0.75 DZA65_RS20795 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 75
Dickeya dianthicola 67-19 0.89 HGI48_RS20405 DNA-binding transcriptional regulator OxyR 0.75 HGI48_RS19710 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 71
Dickeya dadantii 3937 0.89 DDA3937_RS00970 DNA-binding transcriptional regulator OxyR 0.75 DDA3937_RS19580 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA 0.56 33
Serratia liquefaciens MT49 0.88 IAI46_24475 DNA-binding transcriptional regulator OxyR 0.79 IAI46_23740 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 86
Pantoea sp. MT58 0.88 IAI47_00930 DNA-binding transcriptional regulator OxyR 0.79 IAI47_01860 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 76
Rahnella sp. WP5 0.88 EX31_RS14170 DNA-binding transcriptional regulator OxyR 0.78 EX31_RS04750 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA low > 89
Erwinia tracheiphila SCR3 0.87 LU632_RS19590 oxyR DNA-binding transcriptional regulator OxyR 0.77 LU632_RS22900 mrcA peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA
Vibrio cholerae E7946 ATCC 55056 0.63 CSW01_13340 DNA-binding transcriptional regulator OxyR 0.51 CSW01_13335 penicillin-binding protein 1A
Rhodanobacter denitrificans FW104-10B01 0.42 LRK54_RS04765 LysR substrate-binding domain-containing protein 0.34 LRK54_RS11830 penicillin-binding protein 1A low > 59
Rhodanobacter denitrificans MT42 0.42 LRK55_RS04545 LysR substrate-binding domain-containing protein 0.34 LRK55_RS11555 penicillin-binding protein 1A low > 63
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_01995 lysR DNA-binding transcriptional regulator OxyR 0.35 OKGIIK_12065 Penicillin-binding protein 1A low > 52
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.4224.1 Hydrogen peroxide-inducible genes activator 0.30 Xcc-8004.1196.1 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 74
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS19355 DNA-binding transcriptional regulator OxyR 0.34 ABZR86_RS11815 penicillin-binding protein 1A low > 74
Lysobacter sp. OAE881 0.39 ABIE51_RS05475 LysR substrate-binding domain-containing protein 0.31 ABIE51_RS17190 penicillin-binding protein 1A low > 62
Rhodospirillum rubrum S1H 0.37 Rru_A0334 Transcriptional Regulator, LysR family (NCBI) 0.26 Rru_A2147 Penicillin-binding protein 1A (NCBI)
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0202 transcriptional regulator, LysR family 0.37 Psyr_0402 Peptidoglycan glycosyltransferase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0202 transcriptional regulator, LysR family 0.37 Psyr_0402 Peptidoglycan glycosyltransferase low > 86
Pseudomonas stutzeri RCH2 0.36 Psest_4191 Transcriptional regulator 0.36 Psest_3720 penicillin-binding protein, 1A family low > 67
Pseudomonas putida KT2440 0.36 PP_5309 oxidative and nitrosative stress transcriptional dual regulator 0.36 PP_5084 penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase low > 96
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS18935 LysR family transcriptional regulator 0.30 HSERO_RS20890 penicillin-binding protein 1A
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_4353 Hydrogen peroxide-inducible genes activator 0.35 Pf6N2E2_3761 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 103
Azospirillum sp. SherDot2 0.35 MPMX19_04930 Hydrogen peroxide-inducible genes activator 0.26 MPMX19_00340 Penicillin-binding protein 1A
Pseudomonas sp. S08-1 0.35 OH686_13510 Hydrogen peroxide-inducible genes activator 0.35 OH686_10055 Multimodular transpeptidase-transglycosylase low > 80
Pseudomonas simiae WCS417 0.35 PS417_27865 LysR family transcriptional regulator 0.35 PS417_01955 peptidase 0.35 40
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01255 LysR substrate-binding domain-containing protein 0.31 ABZR87_RS02625 penicillin-binding protein 1A
Kangiella aquimarina DSM 16071 0.35 B158DRAFT_0567 Transcriptional regulator 0.38 B158DRAFT_0757 penicillin-binding protein, 1A family
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04673 transcriptional regulator, LysR family 0.31 H281DRAFT_05609 penicillin-binding protein 1A low > 103
Dechlorosoma suillum PS 0.34 Dsui_0823 transcriptional regulator 0.31 Dsui_1186 penicillin-binding protein, 1A family
Pseudomonas fluorescens SBW25 0.34 PFLU_RS29545 hydrogen peroxide-inducible genes activator 0.36 PFLU_RS02000 penicillin-binding protein 1A low > 109
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS17385 LysR family transcriptional regulator 0.30 RR42_RS19040 penicillin-binding protein
Pseudomonas fluorescens FW300-N2C3 0.34 AO356_12385 LysR family transcriptional regulator 0.36 AO356_09420 peptidase low > 104
Ralstonia solanacearum UW163 0.34 UW163_RS08020 hydrogen peroxide-inducible genes activator 0.31 UW163_RS06645 penicillin-binding protein 1A
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS29545 hydrogen peroxide-inducible genes activator 0.36 PFLU_RS02000 penicillin-binding protein 1A low > 109
Ralstonia solanacearum IBSBF1503 0.34 RALBFv3_RS05605 hydrogen peroxide-inducible genes activator 0.31 RALBFv3_RS06970 penicillin-binding protein 1A
Pseudomonas fluorescens GW456-L13 0.34 PfGW456L13_773 Hydrogen peroxide-inducible genes activator 0.35 PfGW456L13_282 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) low > 87
Ralstonia solanacearum GMI1000 0.34 RS_RS13470 hydrogen peroxide-inducible genes activator 0.31 RS_RS14915 penicillin-binding protein 1A
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS03470 LysR family transcriptional regulator 0.31 BPHYT_RS11390 penicillin-binding protein 1A low > 109
Pseudomonas sp. RS175 0.34 PFR28_04434 Hydrogen peroxide-inducible genes activator 0.36 PFR28_05006 Penicillin-binding protein 1A low > 88
Ralstonia solanacearum PSI07 0.34 RPSI07_RS11690 hydrogen peroxide-inducible genes activator 0.31 RPSI07_RS10265 penicillin-binding protein 1A
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS26625 LysR substrate-binding domain-containing protein 0.32 QEN71_RS28065 penicillin-binding protein 1A low > 153
Paraburkholderia graminis OAS925 0.34 ABIE53_000834 LysR family hydrogen peroxide-inducible transcriptional activator 0.31 ABIE53_003746 penicillin-binding protein 1A low > 113
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2106 Hydrogen peroxide-inducible genes activator 0.36 Pf1N1B4_1544 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) 0.34 77
Rhodopseudomonas palustris CGA009 0.34 TX73_002235 LysR substrate-binding domain-containing protein 0.25 TX73_012680 penicillin-binding protein 1A
Sinorhizobium meliloti 1021 0.34 SMc00818 hydrogen peroxide-inducible genes activator (morphology and AUTO-aggregation control protein) 0.24 SMc01334 penicillin-binding 1A transmembrane protein
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_09315 LysR family transcriptional regulator 0.36 AO353_12470 peptidase 0.49 12
Marinobacter adhaerens HP15 0.33 HP15_308 oxidative stress regulatory protein OxyR 0.33 HP15_473 penicillin-binding protein, 1A family
Agrobacterium fabrum C58 0.33 Atu4641 LysR family transcriptional regulator 0.23 Atu1341 penicillin-binding protein 1a
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_03811 LysR-family transcriptional regulator 0.22 CCNA_01951 multimodular transpeptidase-transglycosylase PbpY
Caulobacter crescentus NA1000 0.31 CCNA_03811 LysR-family transcriptional regulator 0.22 CCNA_01951 multimodular transpeptidase-transglycosylase PbpY low > 66
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_0159 Transcriptional regulator 0.20 Ga0059261_2697 Membrane carboxypeptidase/penicillin-binding protein low > 68
Phaeobacter inhibens DSM 17395 0.30 PGA1_78p00040 hydrogen peroxide-inducible genes activator OxyR 0.20 PGA1_c20280 penicillin-binding protein 1A MrcA
Magnetospirillum magneticum AMB-1 0.30 AMB_RS03045 hydrogen peroxide-inducible genes activator 0.24 AMB_RS16340 penicillin-binding protein 1A low > 64
Rhizobium sp. OAE497 0.29 ABIE40_RS29270 LysR substrate-binding domain-containing protein 0.24 ABIE40_RS07555 penicillin-binding protein 1A
Bosea sp. OAE506 0.29 ABIE41_RS01195 hydrogen peroxide-inducible genes activator 0.24 ABIE41_RS16150 penicillin-binding protein 1A low > 77
Dinoroseobacter shibae DFL-12 0.29 Dshi_0727 transcriptional regulator, LysR family (RefSeq) 0.22 Dshi_1171 penicillin-binding protein, 1A family (RefSeq)
Acinetobacter radioresistens SK82 0.28 MPMX26_02334 Hydrogen peroxide-inducible genes activator 0.32 MPMX26_02817 Penicillin-binding protein 1A low > 36
Alteromonas macleodii MIT1002 0.27 MIT1002_01120 Morphology and auto-aggregation control protein 0.46 MIT1002_00454 Penicillin-binding protein 1A low > 70
Brevundimonas sp. GW460-12-10-14-LB2 0.26 A4249_RS12755 hydrogen peroxide-inducible genes activator 0.22 A4249_RS04500 penicillin-binding protein 1A
Shewanella oneidensis MR-1 0.26 SO1328 transcriptional regulator, LysR family (NCBI ptt file) 0.49 SO0280 mrcA penicillin-binding protein 1A (NCBI ptt file)
Shewanella sp. ANA-3 0.26 Shewana3_3046 LysR family transcriptional regulator (RefSeq) 0.48 Shewana3_3900 1A family penicillin-binding protein (RefSeq)
Shewanella loihica PV-4 0.25 Shew_1035 LysR family transcriptional regulator (RefSeq) 0.47 Shew_0207 1A family penicillin-binding protein (RefSeq)
Shewanella amazonensis SB2B 0.24 Sama_0860 LysR family transcriptional regulator (RefSeq) 0.49 Sama_3374 penicillin-binding protein 1A (RefSeq) low > 62

Not shown: 13 genomes with orthologs for BWI76_RS00865 only; 4 genomes with orthologs for BWI76_RS26125 only