| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Agrobacterium fabrum C58 | 1.0 | Atu3296 | | two component response regulator for C4-dicarboxylate transport | 1.0 | Atu0346 | | uridylyltransferase/uridylyl-removing enzyme UTase | 0.25 | 18 |
| Sinorhizobium meliloti 1021 | 0.70 | SM_b20613 | | C4-dicarboxylate transport transcriptional regulator | 0.72 | SMc01124 | | PII uridylyl-transferase | 0.47 | 79 |
| Rhizobium sp. OAE497 | 0.67 | ABIE40_RS26335 | | sigma-54 dependent transcriptional regulator | 0.75 | ABIE40_RS01765 | | [protein-PII] uridylyltransferase | low | > 107 |
| Xanthobacter sp. DMC5 | 0.61 | GFF3675 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.52 | GFF1795 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | — | — |
| Rhodospirillum rubrum S1H | 0.56 | Rru_A1435 | | Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) | 0.41 | Rru_A3539 | | GlnB (protein PII) uridylyltransferase, GlnD (NCBI) | low | > 58 |
| Castellaniella sp019104865 MT123 | 0.55 | ABCV34_RS02725 | | sigma-54 dependent transcriptional regulator | 0.19 | ABCV34_RS04120 | | [protein-PII] uridylyltransferase | low | > 48 |
| Azospirillum sp. SherDot2 | 0.55 | MPMX19_04251 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.42 | MPMX19_00912 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | low | > 112 |
| Azospirillum brasilense Sp245 | 0.53 | AZOBR_RS21130 | | Fis family transcriptional regulator | 0.42 | AZOBR_RS02110 | | protein-PII uridylyltransferase | low | > 97 |
| Pseudomonas stutzeri RCH2 | 0.52 | Psest_4132 | | alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) | 0.24 | Psest_2845 | | [Protein-PII] uridylyltransferase | low | > 67 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.51 | A4249_RS04415 | | sigma-54 dependent transcriptional regulator | 0.33 | A4249_RS13590 | | [protein-PII] uridylyltransferase | low | > 48 |
| Herbaspirillum seropedicae SmR1 | 0.51 | HSERO_RS16810 | | Fis family transcriptional regulator | 0.21 | HSERO_RS10865 | | PII uridylyl-transferase | low | > 78 |
| Pseudomonas segetis P6 | 0.50 | MPMX49_00215 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.23 | MPMX49_03464 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | low | > 75 |
| Pseudomonas fluorescens FW300-N2E3 | 0.50 | AO353_03805 | | C4-dicarboxylate ABC transporter | 0.23 | AO353_16450 | | protein-PII uridylyltransferase | low | > 101 |
| Pseudomonas lactucae CFBP13502 | 0.49 | GEMAOFIL_04682 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.24 | GEMAOFIL_01410 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | low | > 96 |
| Ralstonia sp. UNC404CL21Col | 0.49 | ABZR87_RS16305 | | sigma-54 dependent transcriptional regulator | 0.21 | ABZR87_RS11815 | | [protein-PII] uridylyltransferase | low | > 80 |
| Pseudomonas aeruginosa PUPa3 | 0.49 | DQ20_RS58285 | | sigma-54 dependent transcriptional regulator | 0.24 | DQ20_RS42440 | | [protein-PII] uridylyltransferase | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.49 | DY961_RS25855 | | sigma-54 dependent transcriptional regulator | 0.24 | DY961_RS14685 | | [protein-PII] uridylyltransferase | low | > 100 |
| Pseudomonas aeruginosa PA14 | 0.49 | IKLFDK_25855 | | DNA-binding response regulator | 0.24 | IKLFDK_18680 | | [protein-PII] uridylyltransferase | low | > 98 |
| Pseudomonas fluorescens FW300-N1B4 | 0.49 | Pf1N1B4_685 | | Nitrogen regulation protein NR(I) | 0.24 | Pf1N1B4_3081 | | [Protein-PII] uridylyltransferase (EC 2.7.7.59) | — | — |
| Pseudomonas sp. DMC3 | 0.49 | GFF5041 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.23 | GFF2051 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | low | > 89 |
| Marinobacter adhaerens HP15 | 0.49 | HP15_725 | | two component, sigma54 specific, transcriptional regulator, Fis family | 0.21 | HP15_1163 | | [protein-PII] uridylyltransferase | low | > 73 |
| Pseudomonas fluorescens GW456-L13 | 0.49 | PfGW456L13_1806 | | Nitrogen regulation protein NR(I) | 0.23 | PfGW456L13_4711 | | [Protein-PII] uridylyltransferase (EC 2.7.7.59) | low | > 87 |
| Pseudomonas simiae WCS417 | 0.48 | PS417_22645 | | C4-dicarboxylate ABC transporter | 0.24 | PS417_06200 | | protein-PII uridylyltransferase | low | > 88 |
| Pseudomonas orientalis W4I3 | 0.48 | QF045_RS24815 | | sigma-54 dependent transcriptional regulator | 0.24 | QF045_RS09045 | | [protein-PII] uridylyltransferase | low | > 93 |
| Vibrio cholerae E7946 ATCC 55056 | 0.48 | CSW01_09635 | | sigma-54-dependent Fis family transcriptional regulator | 0.20 | CSW01_11520 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 62 |
| Dechlorosoma suillum PS | 0.48 | Dsui_3486 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | 0.20 | Dsui_2696 | | (protein-PII) uridylyltransferase | low | > 51 |
| Escherichia fergusonii Becca | 0.48 | EFB2_04538 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.21 | EFB2_03878 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | — | — |
| Escherichia coli Nissle 1917 | 0.48 | ECOLIN_RS23460 | | sigma-54 dependent transcriptional regulator | 0.21 | ECOLIN_RS00915 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.48 | AO356_17800 | | C4-dicarboxylate ABC transporter | 0.23 | AO356_06050 | | protein-PII uridylyltransferase | low | > 104 |
| Pseudomonas fluorescens SBW25-INTG | 0.48 | PFLU_RS24280 | | sigma-54-dependent Fis family transcriptional regulator | 0.23 | PFLU_RS06265 | | [protein-PII] uridylyltransferase | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.48 | PFLU_RS24280 | | sigma-54-dependent Fis family transcriptional regulator | 0.23 | PFLU_RS06265 | | [protein-PII] uridylyltransferase | low | > 109 |
| Cupriavidus basilensis FW507-4G11 | 0.48 | RR42_RS01705 | | Fis family transcriptional regulator | 0.20 | RR42_RS11885 | | (protein-PII) uridylyltransferase | low | > 128 |
| Pseudomonas sp. RS175 | 0.48 | PFR28_03462 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | 0.22 | PFR28_00394 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | low | > 88 |
| Ralstonia solanacearum GMI1000 | 0.48 | RS_RS01635 | | sigma-54-dependent Fis family transcriptional regulator | 0.20 | RS_RS07035 | | bifunctional uridylyltransferase/uridylyl-removing protein | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.48 | Pf6N2E2_5487 | | Nitrogen regulation protein NR(I) | 0.23 | Pf6N2E2_3072 | | [Protein-PII] uridylyltransferase (EC 2.7.7.59) | low | > 103 |
| Ralstonia solanacearum IBSBF1503 | 0.47 | RALBFv3_RS10795 | | sigma-54-dependent Fis family transcriptional regulator | 0.20 | RALBFv3_RS00365 | | [protein-PII] uridylyltransferase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.47 | UW163_RS02785 | | sigma-54-dependent Fis family transcriptional regulator | 0.20 | UW163_RS13695 | | [protein-PII] uridylyltransferase | — | — |
| Ralstonia solanacearum PSI07 | 0.47 | RPSI07_RS22520 | | sigma-54-dependent Fis family transcriptional regulator | 0.21 | RPSI07_RS17110 | | [protein-PII] uridylyltransferase | low | > 81 |
| Pseudomonas sp. S08-1 | 0.47 | OH686_13325 | | Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake | 0.25 | OH686_06495 | | protein-P-II uridylyltransferase | low | > 80 |
| Pseudomonas sp. SVBP6 | 0.47 | COO64_RS16760 | | sigma-54 dependent transcriptional regulator | 0.23 | COO64_RS19630 | | [protein-PII] uridylyltransferase | low | > 93 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.47 | H281DRAFT_02037 | | two component, sigma54 specific, transcriptional regulator, NtrC subfamily, Fis family | 0.21 | H281DRAFT_00608 | | UTP--GlnB (protein PII) uridylyltransferase, GlnD | low | > 103 |
| Pseudomonas putida KT2440 | 0.47 | PP_1066 | | C4-dicarboxylate transport transcriptional regulatory protein | 0.24 | PP_1589 | | uridylyltransferase | low | > 96 |
| Paraburkholderia graminis OAS925 | 0.47 | ABIE53_000648 | | two-component system C4-dicarboxylate transport response regulator DctD | 0.21 | ABIE53_002507 | | [protein-PII] uridylyltransferase | low | > 113 |
| Pseudomonas sp. BP01 | 0.47 | JOY50_RS14825 | | sigma-54 dependent transcriptional regulator | 0.24 | JOY50_RS26180 | | [protein-PII] uridylyltransferase | low | > 84 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.47 | Psyr_3995 | | Helix-turn-helix, Fis-type | 0.22 | Psyr_1341 | | Protein-P-II uridylyltransferase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.47 | Psyr_3995 | | Helix-turn-helix, Fis-type | 0.22 | Psyr_1341 | | Protein-P-II uridylyltransferase | low | > 86 |
| Burkholderia phytofirmans PsJN | 0.46 | BPHYT_RS02520 | | Fis family transcriptional regulator | 0.21 | BPHYT_RS12150 | | PII uridylyl-transferase | 0.26 | 56 |
| Shewanella amazonensis SB2B | 0.46 | Sama_2213 | | response regulator receiver protein (RefSeq) | 0.19 | Sama_1137 | | PII uridylyl-transferase (RefSeq) | low | > 62 |
| Paraburkholderia sabiae LMG 24235 | 0.46 | QEN71_RS01375 | | sigma-54 dependent transcriptional regulator | 0.21 | QEN71_RS06410 | | [protein-PII] uridylyltransferase | low | > 153 |
| Sphingomonas koreensis DSMZ 15582 | 0.46 | Ga0059261_0619 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | 0.39 | Ga0059261_2737 | | UTP--GlnB (protein PII) uridylyltransferase, GlnD | low | > 68 |
| Shewanella loihica PV-4 | 0.45 | Shew_1442 | | two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) | 0.20 | Shew_2637 | | PII uridylyl-transferase (RefSeq) | low | > 60 |
| Shewanella oneidensis MR-1 | 0.45 | SO3138 | dctD | C4-dicarboxylate transport transcriptional regulatory protein (NCBI ptt file) | 0.18 | SO1626 | glnD | protein-P-II uridylyltransferase (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.45 | Shewana3_1412 | | two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) | 0.18 | Shewana3_2817 | | PII uridylyl-transferase (RefSeq) | low | > 73 |
| Variovorax sp. OAS795 | 0.43 | ABID97_RS26605 | | sigma-54 dependent transcriptional regulator | 0.19 | ABID97_RS15665 | | [protein-PII] uridylyltransferase | low | > 91 |
| Variovorax sp. SCN45 | 0.42 | GFF1691 | | Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake | 0.19 | GFF1322 | | [Protein-PII] uridylyltransferase (EC 2.7.7.59) / [Protein-PII]-UMP uridylyl-removing enzyme | low | > 127 |
| Sphingobium sp. HT1-2 | 0.38 | GFF159 | | hypothetical protein | 0.40 | GFF4190 | | [Protein-PII] uridylyltransferase (EC 2.7.7.59) / [Protein-PII]-UMP uridylyl-removing enzyme | low | > 95 |
| Klebsiella michiganensis M5al | 0.35 | BWI76_RS21250 | | two-component system response regulator GlrR | 0.21 | BWI76_RS05200 | | bifunctional uridylyltransferase/uridylyl-removing protein | low | > 92 |
| Desulfovibrio vulgaris Miyazaki F | 0.34 | DvMF_0823 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | 0.13 | DvMF_0864 | | UTP-GlnB uridylyltransferase, GlnD (RefSeq) | 0.24 | 30 |
| Klebsiella pneumoniae MKP103 | 0.34 | KDGMDA_28370 | | two-component system response regulator QseF/GlrR | 0.21 | KDGMDA_13445 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | 0.50 | 71 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.34 | GFF2455 | | Putative sensory histidine kinase YfhA | 0.21 | GFF55 | | [Protein-PII] uridylyltransferase (EC 2.7.7.59) | low | > 78 |
| Erwinia amylovora T8 | 0.34 | OLJFJH_10330 | | two-component system response regulator QseF/GlrR | 0.20 | OLJFJH_00645 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.34 | HER17_RS05925 | | two-component system response regulator GlrR | 0.21 | HER17_RS16345 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 75 |
| Rahnella sp. WP5 | 0.34 | EX31_RS20615 | | two-component system response regulator GlrR | 0.21 | EX31_RS13045 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 89 |
| Erwinia tracheiphila SCR3 | 0.34 | LU632_RS17930 | glrR | two-component system response regulator GlrR | 0.20 | LU632_RS19980 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | 0.44 | 46 |
| Erwinia tracheiphila HP pepo 2.2 | 0.34 | IJEDHG_02930 | qseF | two-component system response regulator QseF/GlrR | 0.20 | IJEDHG_15165 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 61 |
| Serratia liquefaciens MT49 | 0.34 | IAI46_19460 | | two-component system response regulator GlrR | 0.21 | IAI46_20270 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 87 |
| Dickeya dianthicola ME23 | 0.34 | DZA65_RS16815 | | two-component system response regulator GlrR | 0.22 | DZA65_RS05445 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 75 |
| Dickeya dadantii 3937 | 0.34 | DDA3937_RS15640 | | two-component system response regulator GlrR | 0.22 | DDA3937_RS05105 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 74 |
| Pantoea agglomerans CFBP13505 P0401 | 0.33 | PagCFBP13505_RS14835 | | two-component system response regulator GlrR | 0.21 | PagCFBP13505_RS13465 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 74 |
| Escherichia coli ECRC62 | 0.33 | BNILDI_11970 | qseF | two-component system response regulator QseF/GlrR | 0.21 | BNILDI_09090 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 75 |
| Escherichia coli ECOR27 | 0.33 | NOLOHH_13170 | qseF | two-component system response regulator QseF/GlrR | 0.21 | NOLOHH_02580 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 76 |
| Dickeya dianthicola 67-19 | 0.33 | HGI48_RS15735 | | two-component system response regulator GlrR | 0.22 | HGI48_RS05105 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 71 |
| Enterobacter sp. TBS_079 | 0.33 | MPMX20_03423 | | Transcriptional regulatory protein QseF | 0.21 | MPMX20_00851 | | Bifunctional uridylyltransferase/uridylyl-removing enzyme | — | — |
| Pantoea sp. MT58 | 0.33 | IAI47_04945 | | two-component system response regulator GlrR | 0.21 | IAI47_15540 | | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | low | > 76 |
| Enterobacter asburiae PDN3 | 0.33 | EX28DRAFT_0096 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | 0.21 | EX28DRAFT_3754 | | UTP--GlnB (protein PII) uridylyltransferase, GlnD | low | > 76 |
| Escherichia coli ECRC98 | 0.33 | JDDGAC_25160 | qseF | two-component system response regulator QseF/GlrR | 0.21 | JDDGAC_13830 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | — | — |
| Escherichia coli ECRC101 | 0.33 | MCAODC_12025 | qseF | two-component system response regulator QseF/GlrR | 0.21 | MCAODC_00750 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | — | — |
| Escherichia coli ECRC100 | 0.33 | OKFHMN_21495 | qseF | two-component system response regulator QseF/GlrR | 0.21 | OKFHMN_10235 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | — | — |
| Escherichia coli ECRC102 | 0.33 | NIAGMN_19265 | qseF | two-component system response regulator QseF/GlrR | 0.21 | NIAGMN_08085 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | — | — |
| Escherichia coli ECRC99 | 0.33 | KEDOAH_06725 | qseF | two-component system response regulator QseF/GlrR | 0.21 | KEDOAH_17920 | glnD | bifunctional uridylyltransferase/uridylyl-removing protein GlnD | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.32 | LRK54_RS12105 | | sigma-54 dependent transcriptional regulator | 0.19 | LRK54_RS03245 | | [protein-PII] uridylyltransferase | — | — |
| Rhodanobacter denitrificans MT42 | 0.32 | LRK55_RS11840 | | sigma-54 dependent transcriptional regulator | 0.19 | LRK55_RS02995 | | [protein-PII] uridylyltransferase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.31 | ABZR86_RS04010 | | sigma-54 dependent transcriptional regulator | 0.19 | ABZR86_RS21575 | | [protein-PII] uridylyltransferase | low | > 74 |
Not shown: 7 genomes with orthologs for Atu3296 only; 22 genomes with orthologs for Atu0346 only