Conservation of cofitness between BT3757 and BT1381 in Bacteroides thetaiotaomicron VPI-5482

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 1.0 BT1381 formyltetrahydrofolate deformylase (NCBI ptt file) 0.90 13
Bacteroides ovatus ATCC 8483 0.92 BACOVA_03587 pyrroline-5-carboxylate reductase 0.99 BACOVA_00222 formyltetrahydrofolate deformylase 0.93 1
Bacteroides stercoris CC31F 0.78 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.89 HMPREF1181_RS11085 formyltetrahydrofolate deformylase low > 56
Phocaeicola vulgatus CL09T03C04 0.69 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.92 HMPREF1058_RS06160 formyltetrahydrofolate deformylase 0.78 47
Phocaeicola dorei CL03T12C01 0.69 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.91 ABI39_RS19915 formyltetrahydrofolate deformylase low > 72
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.33 ABZR88_RS14140 formyltetrahydrofolate deformylase low > 71
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_2479 pyrroline-5-carboxylate reductase 0.61 Echvi_1543 formyltetrahydrofolate deformylase low > 79
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.31 CA265_RS21155 formyltetrahydrofolate deformylase low > 88
Escherichia coli BW25113 0.24 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.38 b1232 purU formyltetrahydrofolate deformylase (NCBI) low > 76
Escherichia coli ECRC62 0.24 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.38 BNILDI_18635 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECOR27 0.24 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.38 NOLOHH_20480 purU formyltetrahydrofolate deformylase low > 57
Synechococcus elongatus PCC 7942 0.24 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.55 Synpcc7942_1008 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECOR38 0.24 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.38 HEPCGN_25030 purU formyltetrahydrofolate deformylase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.38 OHPLBJKB_02453 Formyltetrahydrofolate deformylase low > 73
Erwinia tracheiphila SCR3 0.24 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.37 LU632_RS12940 purU formyltetrahydrofolate deformylase 0.58 47
Escherichia fergusonii Becca 0.24 EFB2_03670 Pyrroline-5-carboxylate reductase 0.38 EFB2_02694 Formyltetrahydrofolate deformylase low > 86
Escherichia coli Nissle 1917 0.24 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.38 ECOLIN_RS07460 formyltetrahydrofolate deformylase low > 52
Escherichia coli BL21 0.24 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.38 ECD_01208 formyltetrahydrofolate hydrolase low > 60
Escherichia coli ECRC101 0.24 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.38 OKFHMN_28570 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC102 0.24 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.38 NIAGMN_27665 purU formyltetrahydrofolate deformylase — —
Klebsiella michiganensis M5al 0.24 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.38 BWI76_RS17290 formyltetrahydrofolate deformylase — —
Escherichia coli ECRC98 0.24 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.38 JDDGAC_06005 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC101 0.24 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.38 MCAODC_21690 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC99 0.24 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.38 KEDOAH_25565 purU formyltetrahydrofolate deformylase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.38 GFF2756 Formyltetrahydrofolate deformylase (EC 3.5.1.10) low > 78
Pseudomonas stutzeri RCH2 0.23 Psest_0283 pyrroline-5-carboxylate reductase 0.46 Psest_3178 formyltetrahydrofolate deformylase — —
Enterobacter asburiae PDN3 0.23 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.38 EX28DRAFT_0858 formyltetrahydrofolate deformylase low > 76
Pseudomonas fluorescens GW456-L13 0.23 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.45 PfGW456L13_1825 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Pseudomonas fluorescens SBW25 0.23 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.45 PFLU_RS24200 formyltetrahydrofolate deformylase — —
Pseudomonas fluorescens SBW25-INTG 0.23 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.45 PFLU_RS24200 formyltetrahydrofolate deformylase — —
Enterobacter sp. TBS_079 0.23 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.38 MPMX20_02596 Formyltetrahydrofolate deformylase low > 85
Pseudomonas putida KT2440 0.23 PP_5095 pyrroline-5-carboxylate reductase 0.44 PP_1367 formyltetrahydrofolate hydrolase low > 96
Alteromonas macleodii MIT1002 0.23 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.40 MIT1002_00404 Formyltetrahydrofolate deformylase low > 70
Pseudomonas simiae WCS417 0.22 PS417_26730 pyrroline-5-carboxylate reductase 0.45 PS417_22565 formyltetrahydrofolate deformylase low > 88
Pseudomonas fluorescens FW300-N2C3 0.22 AO356_13420 pyrroline-5-carboxylate reductase 0.44 AO356_17895 formyltetrahydrofolate deformylase — —
Desulfovibrio vulgaris Miyazaki F 0.22 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.43 DvMF_0189 purU formyltetrahydrofolate deformylase (RefSeq) low > 51
Lysobacter sp. OAE881 0.22 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.37 ABIE51_RS07700 formyltetrahydrofolate deformylase low > 62
Pseudomonas sp. RS175 0.22 PFR28_04243 Pyrroline-5-carboxylate reductase 0.45 PFR28_03439 Formyltetrahydrofolate deformylase — —
Pseudomonas fluorescens FW300-N2E3 0.21 AO353_08165 pyrroline-5-carboxylate reductase 0.45 AO353_03710 formyltetrahydrofolate deformylase low > 101
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.45 Pf6N2E2_5508 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Pantoea sp. MT58 0.21 IAI47_14945 pyrroline-5-carboxylate reductase 0.38 IAI47_09010 formyltetrahydrofolate deformylase low > 76
Pseudomonas syringae pv. syringae B728a 0.21 Psyr_0476 pyrroline-5-carboxylate reductase 0.45 Psyr_4018 Formyltetrahydrofolate deformylase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.21 Psyr_0476 pyrroline-5-carboxylate reductase 0.45 Psyr_4018 Formyltetrahydrofolate deformylase 0.77 26
Desulfovibrio vulgaris Hildenborough JW710 0.21 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.44 DVU1540 purU formyltetrahydrofolate deformylase (TIGR) low > 55
Shewanella loihica PV-4 0.21 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.36 Shew_2640 purU formyltetrahydrofolate deformylase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.20 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.36 SO1624 purU formyltetrahydrofolate deformylase (NCBI ptt file) low > 76
Pseudomonas fluorescens FW300-N1B4 0.20 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.46 Pf1N1B4_665 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Pseudomonas sp. S08-1 0.20 OH686_10980 pyrroline-5-carboxylate reductase 0.45 OH686_18295 formyltetrahydrofolate deformylase low > 80
Shewanella amazonensis SB2B 0.20 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.35 Sama_1134 purU formyltetrahydrofolate deformylase (RefSeq) low > 62
Vibrio cholerae E7946 ATCC 55056 0.20 CSW01_02450 pyrroline-5-carboxylate reductase 0.38 CSW01_09940 formyltetrahydrofolate deformylase low > 62
Paraburkholderia graminis OAS925 0.20 ABIE53_000840 pyrroline-5-carboxylate reductase 0.43 ABIE53_000728 formyltetrahydrofolate deformylase low > 113
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.42 BPHYT_RS02955 formyltetrahydrofolate deformylase — —
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.43 H281DRAFT_01917 formyltetrahydrofolate deformylase — —
Ralstonia sp. UNC404CL21Col 0.19 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.40 ABZR87_RS14235 formyltetrahydrofolate deformylase — —
Shewanella sp. ANA-3 0.19 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.36 Shewana3_2821 purU formyltetrahydrofolate deformylase (RefSeq) low > 73
Castellaniella sp019104865 MT123 0.19 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.42 ABCV34_RS00645 formyltetrahydrofolate deformylase 0.68 30
Herbaspirillum seropedicae SmR1 0.19 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.40 HSERO_RS07970 formyltetrahydrofolate deformylase 0.42 68
Variovorax sp. OAS795 0.18 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.42 ABID97_RS00100 formyltetrahydrofolate deformylase — —
Serratia liquefaciens MT49 0.18 IAI46_21415 pyrroline-5-carboxylate reductase 0.38 IAI46_14265 formyltetrahydrofolate deformylase low > 86
Dickeya dadantii 3937 0.18 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.38 DDA3937_RS10325 formyltetrahydrofolate deformylase 0.62 68
Ralstonia solanacearum GMI1000 0.18 RS_RS13440 pyrroline-5-carboxylate reductase 0.41 RS_RS09460 formyltetrahydrofolate deformylase — —
Dickeya dianthicola ME23 0.18 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.38 DZA65_RS10810 formyltetrahydrofolate deformylase — —
Dickeya dianthicola 67-19 0.18 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.38 HGI48_RS10335 formyltetrahydrofolate deformylase — —
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.45 QEN71_RS33925 formyltetrahydrofolate deformylase low > 153
Ralstonia solanacearum PSI07 0.18 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.40 RPSI07_RS15065 formyltetrahydrofolate deformylase low > 81
Ralstonia solanacearum IBSBF1503 0.18 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.40 RALBFv3_RS02305 formyltetrahydrofolate deformylase 0.46 57
Ralstonia solanacearum UW163 0.18 UW163_RS08045 pyrroline-5-carboxylate reductase 0.40 UW163_RS11420 formyltetrahydrofolate deformylase — —
Pectobacterium carotovorum WPP14 0.17 HER17_RS03805 pyrroline-5-carboxylate reductase 0.39 HER17_RS11065 formyltetrahydrofolate deformylase — —
Variovorax sp. SCN45 0.17 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.41 GFF3790 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Cupriavidus basilensis FW507-4G11 0.17 RR42_RS17360 pyrroline-5-carboxylate reductase 0.40 RR42_RS13800 formyltetrahydrofolate deformylase — —
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.40 Ga0059261_1821 formyltetrahydrofolate deformylase (EC 3.5.1.10) low > 68
Rahnella sp. WP5 0.15 EX31_RS02690 pyrroline-5-carboxylate reductase 0.38 EX31_RS10115 formyltetrahydrofolate deformylase 0.86 75
Xanthomonas campestris pv. campestris strain 8004 0.14 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.40 Xcc-8004.395.1 Formyltetrahydrofolate deformylase (EC 3.5.1.10) low > 74
Rhizobium sp. OAE497 0.14 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.38 ABIE40_RS00960 formyltetrahydrofolate deformylase low > 107
Sinorhizobium meliloti 1021 0.14 SMc02677 pyrroline-5-carboxylate reductase 0.38 SMa2141 formyltetrahydrofolate deformylase low > 103
Caulobacter crescentus NA1000 Δfur 0.13 CCNA_00528 pyrroline-5-carboxylate reductase 0.39 CCNA_03745 formyltetrahydrofolate deformylase low > 67
Caulobacter crescentus NA1000 0.13 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.39 CCNA_03745 formyltetrahydrofolate deformylase 0.83 55
Agrobacterium fabrum C58 0.12 Atu2209 pyrroline-5-carboxylate reductase 0.38 Atu4231 formyltetrahydrofolate deformylase low > 89
Rhodopseudomonas palustris CGA009 0.12 TX73_022630 pyrroline-5-carboxylate reductase 0.41 TX73_020890 formyltetrahydrofolate deformylase — —
Dinoroseobacter shibae DFL-12 0.11 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.39 Dshi_2111 formyltetrahydrofolate deformylase (RefSeq) — —

Not shown: 10 genomes with orthologs for BT3757 only; 10 genomes with orthologs for BT1381 only