| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b1850 | eda | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | 1.0 | b3867 | hemN | O2-independent coproporphyrinogen III oxidase (VIMSS) | 0.37 | 13 |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_04750 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.99 | HEPCGN_12755 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 85 |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_26345 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | OKFHMN_14120 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_01760 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | KEDOAH_14030 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_01879 | | KHG/KDPG aldolase | 1.00 | OHPLBJKB_04186 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 73 |
| Escherichia fergusonii Becca | 1.00 | EFB2_02093 | | KHG/KDPG aldolase | 0.99 | EFB2_04750 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 86 |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_01715 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | NIAGMN_11875 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli BL21 | 1.00 | ECD_01821 | | KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase | 1.00 | ECD_03752 | | coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent | — | — |
| Escherichia coli ECRC62 | 1.00 | BNILDI_15650 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | BNILDI_05280 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_00920 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | JDDGAC_17745 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_19060 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | MCAODC_04620 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS10305 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.99 | ECOLIN_RS22285 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli ECOR27 | 0.99 | NOLOHH_16855 | kdgA | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 1.00 | NOLOHH_06250 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.97 | GFF1629 | | 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.93 | GFF2219 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 78 |
| Enterobacter asburiae PDN3 | 0.96 | EX28DRAFT_0706 | | Entner-Doudoroff aldolase | 0.93 | EX28DRAFT_4348 | | oxygen-independent coproporphyrinogen III oxidase | low | > 76 |
| Enterobacter sp. TBS_079 | 0.96 | MPMX20_02755 | | KHG/KDPG aldolase | 0.93 | MPMX20_04598 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 85 |
| Pectobacterium carotovorum WPP14 | 0.91 | HER17_RS11775 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.83 | HER17_RS21450 | | oxygen-independent coproporphyrinogen III oxidase | low | > 75 |
| Dickeya dadantii 3937 | 0.91 | DDA3937_RS10140 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.79 | DDA3937_RS00120 | | oxygen-independent coproporphyrinogen III oxidase | 0.75 | 13 |
| Dickeya dianthicola 67-19 | 0.91 | HGI48_RS10170 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.79 | HGI48_RS21245 | | oxygen-independent coproporphyrinogen III oxidase | low | > 71 |
| Dickeya dianthicola ME23 | 0.91 | DZA65_RS10585 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.80 | DZA65_RS22220 | | oxygen-independent coproporphyrinogen III oxidase | low | > 75 |
| Pantoea sp. MT58 | 0.89 | IAI47_08500 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.76 | IAI47_00445 | | oxygen-independent coproporphyrinogen III oxidase | 0.36 | 3 |
| Rahnella sp. WP5 | 0.88 | EX31_RS10625 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.79 | EX31_RS15885 | | oxygen-independent coproporphyrinogen III oxidase | low | > 89 |
| Serratia liquefaciens MT49 | 0.88 | IAI46_14570 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.82 | IAI46_24970 | | oxygen-independent coproporphyrinogen III oxidase | low | > 86 |
| Klebsiella michiganensis M5al | 0.87 | BWI76_RS18095 | | ketohydroxyglutarate aldolase | 0.90 | BWI76_RS00380 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Erwinia tracheiphila SCR3 | 0.81 | LU632_RS13355 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.70 | LU632_RS22115 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 74 |
| Shewanella amazonensis SB2B | 0.68 | Sama_1809 | | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) | 0.66 | Sama_0086 | | coproporphyrinogen III oxidase (RefSeq) | — | — |
| Alteromonas macleodii MIT1002 | 0.66 | MIT1002_02403 | | KHG/KDPG aldolase | 0.45 | MIT1002_02323 | | Oxygen-independent coproporphyrinogen-III oxidase | — | — |
| Shewanella oneidensis MR-1 | 0.66 | SO2486 | eda | 2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (NCBI ptt file) | 0.67 | SO4730 | hemN | oxygen-independent coproporphyrinogen III oxidase (NCBI ptt file) | — | — |
| Shewanella loihica PV-4 | 0.65 | Shew_2045 | | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) | 0.66 | Shew_3720 | | coproporphyrinogen III oxidase (RefSeq) | — | — |
| Shewanella sp. ANA-3 | 0.65 | Shewana3_2148 | | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) | 0.66 | Shewana3_4116 | | coproporphyrinogen III oxidase (RefSeq) | — | — |
| Herbaspirillum seropedicae SmR1 | 0.52 | HSERO_RS05525 | | ketohydroxyglutarate aldolase | 0.47 | HSERO_RS16075 | | coproporphyrinogen III oxidase | — | — |
| Ralstonia solanacearum PSI07 | 0.50 | RPSI07_RS05475 | | ketohydroxyglutarate aldolase | 0.46 | RPSI07_RS08635 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Marinobacter adhaerens HP15 | 0.49 | HP15_2177 | | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | 0.49 | HP15_2953 | | oxygen-independent coproporphyrinogen III oxidase | low | > 73 |
| Pseudomonas stutzeri RCH2 | 0.49 | Psest_0854 | | Entner-Doudoroff aldolase | 0.47 | Psest_2537 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Phaeobacter inhibens DSM 17395 | 0.49 | PGA1_c28010 | | KHG/KDPG aldolase | 0.30 | PGA1_c00360 | | oxygen-independent coproporphyrinogen III oxidase HemN | — | — |
| Rhodanobacter denitrificans MT42 | 0.49 | LRK55_RS07615 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.45 | LRK55_RS05590 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas putida KT2440 | 0.49 | PP_1024 | | KHG/KDPG aldolase | 0.48 | PP_4264 | | oxygen-independent coproporphyrinogen III dehydrogenase | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.48 | LRK54_RS07885 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.45 | LRK54_RS05835 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Variovorax sp. OAS795 | 0.48 | ABID97_RS21295 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.45 | ABID97_RS16190 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS14685 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.45 | ABZR86_RS04455 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas sp. S08-1 | 0.48 | OH686_02425 | | 4-hydroxy-2-oxoglutarate aldolase or 2-dehydro-3-deoxyphosphogluconate aldolase | 0.48 | OH686_02235 | | oxygen-independent coproporphyrinogen III oxidase | low | > 80 |
| Sinorhizobium meliloti 1021 | 0.48 | SMc03153 | | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase | 0.32 | SMa1266 | | coproporphyrinogen III oxidase | low | > 103 |
| Variovorax sp. SCN45 | 0.47 | GFF6512 | | 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.43 | GFF6957 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 127 |
| Ralstonia solanacearum GMI1000 | 0.47 | RS_RS22875 | | ketohydroxyglutarate aldolase | 0.46 | RS_RS16455 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Rhodanobacter sp. FW510-T8 | 0.47 | OKGIIK_14375 | eda | 2-keto-3-deoxy-6-phosphogluconate aldolase | 0.44 | OKGIIK_00800 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Acidovorax sp. GW101-3H11 | 0.47 | Ac3H11_2083 | | 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.47 | Ac3H11_976 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | — | — |
| Ralstonia solanacearum UW163 | 0.47 | UW163_RS20970 | | ketohydroxyglutarate aldolase | 0.46 | UW163_RS05010 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.47 | RALBFv3_RS18160 | | ketohydroxyglutarate aldolase | 0.46 | RALBFv3_RS08600 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas sp. RS175 | 0.46 | PFR28_00575 | | 2-dehydro-3-deoxy-phosphogluconate aldolase | 0.49 | PFR28_01080 | | Oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.46 | AO356_05150 | | keto-deoxy-phosphogluconate aldolase | 0.48 | AO356_02480 | | coproporphyrinogen III oxidase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.46 | Pf1N1B4_587 | | 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.48 | Pf1N1B4_3868 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | — | — |
| Agrobacterium fabrum C58 | 0.46 | Atu4494 | | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase | 0.32 | Atu1601 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.46 | PfGW456L13_1903 | | 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.49 | PfGW456L13_4070 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.46 | AO353_03350 | | keto-deoxy-phosphogluconate aldolase | 0.48 | AO353_00655 | | coproporphyrinogen III oxidase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.46 | Psyr_1122 | | 2-keto-3-deoxy-phosphogluconate aldolase | 0.48 | Psyr_3423 | | coproporphyrinogen III oxidase, anaerobic | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.46 | Psyr_1122 | | 2-keto-3-deoxy-phosphogluconate aldolase | 0.48 | Psyr_3423 | | coproporphyrinogen III oxidase, anaerobic | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.46 | Pf6N2E2_2883 | | 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.48 | Pf6N2E2_2321 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | — | — |
| Ralstonia sp. UNC404CL21Col | 0.46 | ABZR87_RS19090 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.46 | ABZR87_RS03910 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas fluorescens SBW25 | 0.46 | PFLU_RS23715 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.49 | PFLU_RS22385 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.46 | PFLU_RS23715 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.49 | PFLU_RS22385 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Pseudomonas simiae WCS417 | 0.46 | PS417_22100 | | keto-deoxy-phosphogluconate aldolase | 0.49 | PS417_20775 | | coproporphyrinogen III oxidase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.45 | RR42_RS28865 | | 2-dehydro-3-deoxyphosphogluconate aldolase | 0.44 | RR42_RS20025 | | coproporphyrinogen III oxidase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.45 | GFF5496 | | 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) | 0.46 | GFF4143 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | — | — |
| Bosea sp. OAE506 | 0.45 | ABIE41_RS23505 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.34 | ABIE41_RS12085 | | oxygen-independent coproporphyrinogen III oxidase | low | > 77 |
| Castellaniella sp019104865 MT123 | 0.45 | ABCV34_RS08610 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.44 | ABCV34_RS06465 | | oxygen-independent coproporphyrinogen III oxidase | low | > 48 |
| Lysobacter sp. OAE881 | 0.45 | ABIE51_RS01605 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.45 | ABIE51_RS03875 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.45 | QEN71_RS26915 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.47 | QEN71_RS03200 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Rhizobium sp. OAE497 | 0.44 | ABIE40_RS16720 | | 2-dehydro-3-deoxy-phosphogluconate aldolase | 0.33 | ABIE40_RS26250 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Burkholderia phytofirmans PsJN | 0.44 | BPHYT_RS16730 | | 2-dehydro-3-deoxyphosphogluconate aldolase | 0.47 | BPHYT_RS15490 | | coproporphyrinogen III oxidase | — | — |
| Paraburkholderia graminis OAS925 | 0.44 | ABIE53_003516 | | 2-dehydro-3-deoxyphosphogluconate aldolase/(4S)-4-hydroxy-2-oxoglutarate aldolase | 0.46 | ABIE53_003264 | | oxygen-independent coproporphyrinogen-3 oxidase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_04277 | | 2-keto-3-deoxy-phosphogluconate aldolase | 0.45 | H281DRAFT_04040 | | oxygen-independent coproporphyrinogen-3 oxidase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.42 | Dshi_1768 | | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (RefSeq) | 0.34 | Dshi_0541 | | oxygen-independent coproporphyrinogen III oxidase (RefSeq) | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.41 | Xcc-8004.2446.1 | | hypothetical protein | 0.40 | Xcc-8004.2605.1 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.40 | CSW01_01465 | | ketohydroxyglutarate aldolase | 0.71 | CSW01_00590 | | oxygen-independent coproporphyrinogen III oxidase | low | > 62 |
| Azospirillum brasilense Sp245 | 0.39 | AZOBR_RS29850 | | ketohydroxyglutarate aldolase | 0.33 | AZOBR_RS03710 | | coproporphyrinogen III oxidase | — | — |
| Parabacteroides merdae CL09T00C40 | 0.22 | HMPREF1078_RS05610 | | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | 0.32 | HMPREF1078_RS13395 | | oxygen-independent coproporphyrinogen III oxidase | low | > 61 |
| Caulobacter crescentus NA1000 Δfur | 0.20 | CCNA_01562 | | 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase | 0.27 | CCNA_01477 | | oxygen-independent coproporphyrinogen-III oxidase hemN | low | > 67 |
| Caulobacter crescentus NA1000 | 0.20 | CCNA_01562 | | 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase | 0.27 | CCNA_01477 | | oxygen-independent coproporphyrinogen-III oxidase hemN | low | > 66 |
Not shown: 7 genomes with orthologs for b1850 only; 10 genomes with orthologs for b3867 only