Conservation of cofitness between b0142 and b0032 in Escherichia coli BW25113

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0142 folK 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) 1.0 b0032 carA carbamoyl-phosphate synthase small subunit (NCBI) 0.57 17
Escherichia coli BL21 0.97 ECD_00141 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase 1.00 ECD_00036 carbamoyl phosphate synthetase small subunit, glutamine amidotransferase
Escherichia coli ECOR27 0.97 NOLOHH_02705 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 NOLOHH_03275 carA carbamoyl phosphate synthase small subunit
Escherichia coli ECRC62 0.97 BNILDI_08965 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 BNILDI_08325 carA carbamoyl phosphate synthase small subunit
Escherichia coli ECOR38 0.97 HEPCGN_08310 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.99 HEPCGN_08930 carA carbamoyl phosphate synthase small subunit
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_03520 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1.00 OHPLBJKB_03625 Carbamoyl-phosphate synthase small chain
Escherichia coli ECRC98 0.90 JDDGAC_13955 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 JDDGAC_14540 carA carbamoyl phosphate synthase small subunit
Escherichia coli ECRC101 0.90 MCAODC_00875 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 MCAODC_01460 carA carbamoyl phosphate synthase small subunit
Escherichia coli ECRC99 0.90 KEDOAH_17795 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 KEDOAH_17210 carA carbamoyl phosphate synthase small subunit
Escherichia coli ECRC102 0.90 NIAGMN_08210 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 NIAGMN_08795 carA carbamoyl phosphate synthase small subunit
Escherichia coli Nissle 1917 0.90 ECOLIN_RS00785 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.99 ECOLIN_RS00175 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Escherichia coli ECRC101 0.90 OKFHMN_10360 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 OKFHMN_10945 carA carbamoyl phosphate synthase small subunit
Escherichia fergusonii Becca 0.90 EFB2_03902 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.99 EFB2_04013 Carbamoyl-phosphate synthase small chain 0.26 78
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.83 GFF90 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.96 GFF214 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Klebsiella michiganensis M5al 0.79 BWI76_RS05000 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.96 BWI76_RS04465 carbamoyl-phosphate synthase small subunit
Enterobacter sp. TBS_079 0.79 MPMX20_00828 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.92 MPMX20_00739 Carbamoyl-phosphate synthase small chain
Enterobacter asburiae PDN3 0.78 EX28DRAFT_3731 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.96 EX28DRAFT_3637 carbamoyl-phosphate synthase, small subunit
Pectobacterium carotovorum WPP14 0.67 HER17_RS05565 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.88 HER17_RS02895 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit low > 75
Rahnella sp. WP5 0.67 EX31_RS03265 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.89 EX31_RS03835 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Dickeya dianthicola ME23 0.64 DZA65_RS17150 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.85 DZA65_RS19385 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Dickeya dianthicola 67-19 0.64 HGI48_RS16065 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.85 HGI48_RS18245 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Dickeya dadantii 3937 0.64 DDA3937_RS15950 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.86 DDA3937_RS18310 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Pantoea sp. MT58 0.63 IAI47_15650 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.86 IAI47_16120 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Serratia liquefaciens MT49 0.63 IAI46_21225 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.86 IAI46_03190 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Erwinia tracheiphila SCR3 0.62 LU632_RS20095 folK 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.84 LU632_RS02755 carA glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Vibrio cholerae E7946 ATCC 55056 0.61 CSW01_03140 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.84 CSW01_12105 carbamoyl-phosphate synthase small subunit
Pseudomonas stutzeri RCH2 0.56 Psest_0997 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.69 Psest_0967 carbamoyl-phosphate synthase, small subunit
Pseudomonas sp. S08-1 0.54 OH686_17250 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.70 OH686_17075 Carbamoyl-phosphate synthase small chain
Alteromonas macleodii MIT1002 0.51 MIT1002_03693 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.74 MIT1002_01466 Carbamoyl-phosphate synthase small chain
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_14390 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.70 AO353_05635 carbamoyl phosphate synthase small subunit
Pseudomonas fluorescens SBW25 0.45 PFLU_RS25745 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.68 PFLU_RS25885 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS25745 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.68 PFLU_RS25885 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Shewanella amazonensis SB2B 0.45 Sama_0777 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase (RefSeq) 0.80 Sama_2504 carbamoyl phosphate synthase small subunit (RefSeq)
Marinobacter adhaerens HP15 0.44 HP15_325 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.70 HP15_3078 carbamoyl-phosphate synthase small chain
Pseudomonas sp. RS175 0.44 PFR28_03720 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.69 PFR28_00076 Carbamoyl-phosphate synthase small chain
Shewanella sp. ANA-3 0.42 Shewana3_3407 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.77 Shewana3_0967 carbamoyl phosphate synthase small subunit (RefSeq)
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0059 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.73 B158DRAFT_0615 carbamoyl-phosphate synthase, small subunit
Pseudomonas syringae pv. syringae B728a 0.41 Psyr_0829 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 0.69 Psyr_4192 carbamoyl-phosphate synthase small subunit
Pseudomonas syringae pv. syringae B728a ΔmexB 0.41 Psyr_0829 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 0.69 Psyr_4192 carbamoyl-phosphate synthase small subunit
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_16065 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.69 AO356_07485 carbamoyl phosphate synthase small subunit
Shewanella oneidensis MR-1 0.41 SO0871 folK-1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (NCBI ptt file) 0.78 SO1141 carA carbamoyl-phosphate synthase, small subunit (NCBI ptt file) 0.64 63
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_1522 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.70 PfGW456L13_5100 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_5154 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.69 Pf6N2E2_3365 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Xanthomonas campestris pv. campestris strain 8004 0.40 Xcc-8004.3053.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.64 Xcc-8004.2914.1 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_2855 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.69 Pf1N1B4_1173 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Pseudomonas simiae WCS417 0.39 PS417_23905 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.69 PS417_24045 carbamoyl phosphate synthase small subunit
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS00810 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.64 ABZR86_RS05605 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS15110 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.65 LRK54_RS17995 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Pseudomonas putida KT2440 0.37 PP_4698 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0.69 PP_4724 Carbamoyl-phosphate synthase small chain
Rhodanobacter denitrificans MT42 0.37 LRK55_RS14825 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.65 LRK55_RS17850 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_03880 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.64 OKGIIK_07300 carbamoyl phosphate synthase small subunit
Echinicola vietnamensis KMM 6221, DSM 17526 0.35 Echvi_2784 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.38 Echvi_0226 carbamoyl-phosphate synthase, small subunit
Acinetobacter radioresistens SK82 0.35 MPMX26_00544 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.69 MPMX26_00767 Carbamoyl-phosphate synthase small chain
Agrobacterium fabrum C58 0.34 Atu1354 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0.47 Atu2170 carbamoylphosphate synthase small chain
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF3439 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.63 GFF4899 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Shewanella loihica PV-4 0.34 Shew_3132 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.77 Shew_2839 carbamoyl phosphate synthase small subunit (RefSeq)
Pedobacter sp. GW460-11-11-14-LB5 0.33 CA265_RS04420 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.40 CA265_RS15240 carbamoyl phosphate synthase small subunit
Magnetospirillum magneticum AMB-1 0.33 AMB_RS11625 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.53 AMB_RS03600 carbamoyl-phosphate synthase small subunit
Synechococcus elongatus PCC 7942 0.32 Synpcc7942_2272 folK 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.45 Synpcc7942_2122 carA carbamoyl phosphate synthase small subunit
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS03140 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.65 HSERO_RS06920 carbamoyl phosphate synthase small subunit
Rhodopseudomonas palustris CGA009 0.30 TX73_009450 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.51 TX73_006555 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Parabacteroides merdae CL09T00C40 0.30 HMPREF1078_RS17100 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.33 HMPREF1078_RS01295 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_0362 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.38 DvMF_2370 carbamoyl phosphate synthase small subunit (RefSeq)
Mucilaginibacter yixingensis YX-36 DSM 26809 0.30 ABZR88_RS13920 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.39 ABZR88_RS17830 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Azospirillum brasilense Sp245 0.29 AZOBR_RS14885 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.52 AZOBR_RS10920 carbamoyl phosphate synthase small subunit
Pontibacter actiniarum KMM 6156, DSM 19842 0.28 CA264_10765 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.39 CA264_19490 carbamoyl phosphate synthase small subunit
Dechlorosoma suillum PS 0.27 Dsui_1514 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.66 Dsui_3065 carbamoyl-phosphate synthase, small subunit
Phocaeicola vulgatus CL09T03C04 0.27 HMPREF1058_RS11325 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.33 HMPREF1058_RS06875 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Phocaeicola dorei CL03T12C01 0.27 ABI39_RS05605 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.34 ABI39_RS20670 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Ralstonia solanacearum GMI1000 0.27 RS_RS13170 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.65 RS_RS07620 carbamoyl-phosphate synthase small subunit
Phaeobacter inhibens DSM 17395 0.27 PGA1_c00990 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK 0.49 PGA1_c06670 carbamoyl-phosphate synthase small chain
Ralstonia solanacearum PSI07 0.27 RPSI07_RS11995 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.66 RPSI07_RS15245 carbamoyl-phosphate synthase small subunit
Ralstonia solanacearum UW163 0.27 UW163_RS08320 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.66 UW163_RS15510 carbamoyl-phosphate synthase small subunit
Ralstonia solanacearum IBSBF1503 0.27 RALBFv3_RS05305 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.66 RALBFv3_RS02200 carbamoyl-phosphate synthase small subunit
Bacteroides stercoris CC31F 0.27 HMPREF1181_RS01700 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.33 HMPREF1181_RS16070 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
Rhodospirillum rubrum S1H 0.24 Rru_A1858 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (NCBI) 0.49 Rru_A2885 Carbamoyl-phosphate synthase, small subunit (NCBI)
Bacteroides thetaiotaomicron VPI-5482 0.22 BT3216 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine (NCBI ptt file) 0.32 BT0556 carbamoyl phosphate synthetase III (glutamine-hydrolyzing) (NCBI ptt file)
Bacteroides ovatus ATCC 8483 0.22 BACOVA_02916 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.33 BACOVA_03753 carbamoyl-phosphate synthase, small subunit
Sphingomonas koreensis DSMZ 15582 0.19 Ga0059261_1977 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.49 Ga0059261_4243 carbamoyl-phosphate synthase, small subunit
Dinoroseobacter shibae DFL-12 0.18 Dshi_0192 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.49 Dshi_2387 carbamoyl-phosphate synthase, small subunit (RefSeq)
Caulobacter crescentus NA1000 Δfur 0.17 CCNA_01620 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.47 CCNA_02925 carbamoyl-phosphate synthase small chain
Caulobacter crescentus NA1000 0.17 CCNA_01620 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.47 CCNA_02925 carbamoyl-phosphate synthase small chain

Not shown: 0 genomes with orthologs for b0142 only; 22 genomes with orthologs for b0032 only