| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Pseudomonas putida KT2440 | PP_0355 | | Response regulator | sig. | 100 | 100 |
| o | Pseudomonas sp. BP01 | JOY50_RS17895 | | response regulator | insig. | 89 | 95 |
| | Pseudomonas sp. SVBP6 | COO64_RS22765 | | response regulator | insig. | 55 | 78 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2477 | | response regulator | insig. | 54 | 78 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_4701 | | Response regulator receiver | no data | 49 | 79 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4701 | | Response regulator receiver | no data | 49 | 79 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1138 | | response regulator | insig. | 54 | 78 |
| | Pseudomonas sp. DMC3 | GFF84 | | Regulatory protein AtoC | no data | 53 | 78 |
| | Pseudomonas orientalis W4I3 | QF045_RS00455 | | response regulator | insig. | 51 | 77 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_14095 | | response regulator | no data | 53 | 77 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS27690 | | response regulator | no data | 50 | 77 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS27690 | | response regulator | insig. | 50 | 77 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_07565 | | response regulator | no data | 51 | 77 |
| | Pseudomonas sp. RS175 | PFR28_04111 | | Regulatory protein AtoC | no data | 53 | 77 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4751 | | response regulator | insig. | 53 | 77 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05330 | | Regulatory protein AtoC | insig. | 51 | 77 |
| | Pseudomonas simiae WCS417 | PS417_26050 | | response regulator | sig. | 50 | 77 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2109 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 36 | 74 |
| | Dechlorosoma suillum PS | Dsui_2080 | | response regulator | cofit | 37 | 66 |
| | Pseudomonas segetis P6 | ACVTMO_RS20050 | | response regulator | insig. | 36 | 63 |
| | Pseudomonas orientalis W4I3 | QF045_RS06155 | | response regulator | insig. | 35 | 65 |
| | Pseudomonas segetis P6 | ACVTMO_RS19460 | | sigma-54-dependent transcriptional regulator | cofit | 34 | 64 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS05575 | | Fis family transcriptional regulator | strong | 31 | 64 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00240 | | two component, sigma54 specific, transcriptional regulator, NtrC subfamily, Fis family | strong | 31 | 64 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_2527 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | sig. | 32 | 63 |
| | Caulobacter crescentus NA1000 | CCNA_00795 | | two-component response regulator FixJ | strong | 36 | 61 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00795 | | two-component response regulator FixJ | cofit | 36 | 61 |
| | Pseudomonas sp. RS175 | PFR28_01140 | | Regulator of RpoS | no data | 36 | 59 |
| | Pseudomonas sp. DMC3 | GFF3335 | | Response regulator protein TmoT | cofit | 32 | 61 |
| | Paraburkholderia graminis OAS925 | ABIE53_001365 | | DNA-binding NtrC family response regulator | strong | 31 | 64 |
| | Pseudomonas sp. SVBP6 | COO64_RS09545 | rssB | two-component system response regulator RssB | no data | 38 | 55 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS24605 | | DNA-binding response regulator | no data | 31 | 89 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS12850 | | LuxR family transcriptional regulator | no data | 35 | 66 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00464 | | two component transcriptional regulator, LuxR family | no data | 35 | 66 |
| | Paraburkholderia graminis OAS925 | ABIE53_002795 | | FixJ family two-component response regulator | no data | 35 | 66 |
| | Pseudomonas putida KT2440 | PP_2165 | | Response regulator | no data | 38 | 55 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS11155 | | sigma-54-dependent Fis family transcriptional regulator | cofit | 39 | 59 |
| | Ralstonia solanacearum GMI1000 | RS_RS14035 | | sigma-54-dependent Fis family transcriptional regulator | strong | 39 | 61 |
| | Pseudomonas sp. BP01 | JOY50_RS25185 | rssB | two-component system response regulator RssB | no data | 38 | 55 |
| | Pseudomonas sp. DMC3 | GFF3346 | | Regulator of RpoS | cofit | 42 | 46 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS06085 | | sigma-54-dependent Fis family transcriptional regulator | strong | 39 | 59 |
| | Ralstonia solanacearum UW163 | UW163_RS07540 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 39 | 59 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS01680 | | DNA-binding response regulator | no data | 36 | 66 |
| | Ralstonia solanacearum UW163 | UW163_RS14990 | | DNA-binding response regulator | no data | 36 | 66 |
| | Klebsiella michiganensis M5al | BWI76_RS14480 | | hypothetical protein | insig. | 35 | 62 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03150 | | response regulator transcription factor | insig. | 30 | 61 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03150 | | response regulator transcription factor | sig. | 30 | 61 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS01750 | | sigma-54 dependent transcriptional regulator | strong | 38 | 59 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS13480 | | response regulator transcription factor | no data | 37 | 66 |
| | Ralstonia solanacearum GMI1000 | RS_RS08045 | | DNA-binding response regulator | cofit | 37 | 66 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS15805 | | DNA-binding response regulator | no data | 37 | 66 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS23710 | pilR;inference=COORDINATES | two-component system response regulator PilR | strong | 36 | 65 |
| | Pseudomonas sp. S08-1 | OH686_16390 | | Type IV fimbriae expression regulatory protein PilR | cofit | 31 | 66 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_00790 | | two-component response regulator PilR | strong | 36 | 65 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS56175 | pilR;inference=COORDINATES | two-component system response regulator PilR | strong | 36 | 65 |
| | Pseudomonas stutzeri RCH2 | Psest_0705 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 33 | 68 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5122 | | Type IV fimbriae expression regulatory protein PilR | insig. | 34 | 65 |
| | Escherichia coli ECOR38 | HEPCGN_10745 | pgtA | two-component system response regulator PgtA | insig. | 33 | 62 |
| | Pseudomonas sp. DMC3 | GFF1302 | | Regulator of RpoS | no data | 36 | 55 |
| | Methylophilus sp. DMC18 | GFF2815 | | Regulatory protein AtoC | insig. | 36 | 62 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_15905 | | transcriptional regulator | insig. | 34 | 65 |
| | Dechlorosoma suillum PS | Dsui_1758 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | cofit | 33 | 60 |
| | Pseudomonas simiae WCS417 | PS417_03120 | | histidine kinase | insig. | 34 | 65 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1991 | | response regulator receiver protein (RefSeq) | no data | 37 | 59 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 36 | 55 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 36 | 55 |
| | Xanthobacter sp. DMC5 | GFF4834 | | Regulatory protein AtoC | insig. | 31 | 62 |
| | Pseudomonas sp. RS175 | PFR28_03751 | | Regulatory protein AtoC | insig. | 34 | 65 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4408 | | two-component response regulator | insig. | 37 | 62 |
| | Escherichia fergusonii Becca | EFB2_00910 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | insig. | 32 | 62 |
| | Dechlorosoma suillum PS | Dsui_1581 | | response regulator | strong | 31 | 66 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS24790 | | sigma-54 dependent transcriptional regulator | cofit | 29 | 64 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_14200 | | transcriptional regulator | insig. | 34 | 66 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02185 | | chemotaxis protein CheY | no data | 35 | 55 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_13785 | | LuxR family transcriptional regulator | insig. | 30 | 61 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS04170 | | response regulator transcription factor | no data | 37 | 59 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS05715 | | oxygen response regulator transcription factor FixJ | no data | 34 | 66 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14325 | | histidine kinase | cofit | 37 | 58 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2260 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 35 | 55 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03200 | | response regulator | insig. | 34 | 62 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03200 | | response regulator | insig. | 34 | 62 |
| | Pseudomonas orientalis W4I3 | QF045_RS06105 | | response regulator transcription factor | cofit | 28 | 61 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_4388 | | Response regulator receiver | sig. | 44 | 38 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4388 | | Response regulator receiver | insig. | 44 | 38 |
| | Agrobacterium fabrum C58 | Atu1116 | | two component response regulator | insig. | 38 | 63 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4011 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 35 | 55 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_60 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 35 | 55 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS01375 | | sigma-54 dependent transcriptional regulator | strong | 34 | 62 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1273 | | Response regulator | insig. | 40 | 44 |
| | Pseudomonas segetis P6 | ACVTMO_RS09490 | rssB | two-component system response regulator RssB | no data | 38 | 61 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS15535 | | response regulator | no data | 33 | 61 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0722 | | Two-component response regulator PilR | insig. | 32 | 66 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0722 | | Two-component response regulator PilR | insig. | 32 | 66 |
| | Agrobacterium fabrum C58 | Atu3296 | | two component response regulator for C4-dicarboxylate transport | strong | 32 | 62 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_21110 | | two-component system response regulator DcuR | insig. | 35 | 58 |
| | Rhizobium sp. OAE497 | ABIE40_RS30355 | | response regulator | insig. | 38 | 59 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1419 | | signal transduction histidine kinase (RefSeq) | cofit | 35 | 56 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS10715 | aruR;inference=COORDINATES | two-component system response regulator AruR | sig. | 35 | 56 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_28620 | | Transcriptional regulatory protein AruR | sig. | 35 | 56 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS51345 | aruR;inference=COORDINATES | two-component system response regulator AruR | sig. | 35 | 56 |