| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Variovorax sp. SCN45 | GFF3503 | | Subclass B3 beta-lactamase (EC 3.5.2.6) | insig. | 100 | 100 |
| | Dickeya dadantii 3937 | DDA3937_RS11935 | | CAR family subclass B3 metallo-beta-lactamase | insig. | 40 | 69 |
| | Dickeya dianthicola ME23 | DZA65_RS12475 | | CAR family subclass B3 metallo-beta-lactamase | insig. | 40 | 69 |
| | Dickeya dianthicola 67-19 | HGI48_RS12025 | | CAR family subclass B3 metallo-beta-lactamase | insig. | 41 | 67 |
| | Caulobacter crescentus NA1000 | CCNA_02223 | | beta-lactamase, type II | strong | 30 | 67 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02223 | | beta-lactamase, type II | cofit | 30 | 67 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS09730 | | subclass B3 metallo-beta-lactamase | sig. | 25 | 61 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3143 | | Zn-dependent hydrolases, including glyoxylases | strong | 28 | 67 |
| | Sphingobium sp. HT1-2 | GFF3111 | | Subclass B3 beta-lactamase (EC 3.5.2.6) | cofit | 30 | 64 |
| | Serratia liquefaciens MT49 | IAI46_17405 | | HARLDQ motif MBL-fold protein | insig. | 28 | 82 |
| | Lysobacter sp. OAE881 | ABIE51_RS06365 | | subclass B3 metallo-beta-lactamase | insig. | 28 | 63 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17105 | | subclass B3 metallo-beta-lactamase | cofit | 29 | 45 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS10070 | | subclass B3 metallo-beta-lactamase | insig. | 27 | 47 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS18080 | | subclass B3 metallo-beta-lactamase | insig. | 27 | 65 |
| | Acinetobacter radioresistens SK82 | MPMX26_01975 | | hypothetical protein | no data | 28 | 45 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS05510 | | subclass B3 metallo-beta-lactamase | insig. | 26 | 64 |
| | Azospirillum sp. SherDot2 | MPMX19_06029 | | Hydroxyacylglutathione hydrolase GloB | insig. | 31 | 33 |
| | Rhodopseudomonas palustris CGA009 | TX73_003155 | | hydroxyacylglutathione hydrolase | sig. | 34 | 32 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17935 | | subclass B3 metallo-beta-lactamase | insig. | 26 | 63 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_07220 | bla | subclass B3 metallo-beta-lactamase | insig. | 26 | 66 |
| | Fusobacterium nucleatum SB010 | HUW76_06550 | | MBL fold metallo-hydrolase | strong | 40 | 26 |
| | Paraburkholderia graminis OAS925 | ABIE53_000468 | | hydroxyacylglutathione hydrolase | sig. | 36 | 35 |
| | Pectobacterium carotovorum WPP14 | HER17_RS12035 | | MBL fold metallo-hydrolase | insig. | 33 | 38 |
| | Shewanella sp. ANA-3 | Shewana3_1493 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 35 | 30 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF363 | | Putative beta-lactamase | insig. | 25 | 71 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS01930 | | hypothetical protein | insig. | 35 | 35 |
| | Cellulophaga baltica 18 | M666_RS00700 | | MBL fold metallo-hydrolase | insig. | 33 | 35 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS20840 | | beta-lactamase | insig. | 33 | 43 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS11580 | | beta-lactamase | insig. | 33 | 35 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS00645 | | MBL fold metallo-hydrolase | insig. | 33 | 35 |
| | Rhodopseudomonas palustris CGA009 | TX73_001890 | | MBL fold metallo-hydrolase | insig. | 28 | 43 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3684 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 31 | 37 |
| | Xanthobacter sp. DMC5 | GFF3817 | | Hydroxyacylglutathione hydrolase GloC | insig. | 27 | 37 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS16385 | | beta-lactamase | insig. | 31 | 27 |
| | Mycobacterium tuberculosis H37Rv | Rv2260 | | Conserved hypothetical protein | insig. | 34 | 37 |
| | Agrobacterium fabrum C58 | Atu2201 | | hydrolase | insig. | 31 | 25 |
| | Acinetobacter baumannii LAC-4 | RR41_RS17080 | | MBL fold metallo-hydrolase | insig. | 29 | 49 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1761 | | Hydroxyacylglutathione hydrolase | insig. | 31 | 25 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1761 | | Hydroxyacylglutathione hydrolase | insig. | 31 | 25 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2293 | | Zn-dependent hydrolases, including glyoxylases | insig. | 30 | 44 |
| | Methanococcus maripaludis JJ | MMJJ_RS04795 | | MBL fold metallo-hydrolase | insig. | 30 | 40 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0078 | | Beta-lactamase-like protein | sig. | 29 | 28 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0078 | | Beta-lactamase-like protein | insig. | 29 | 28 |
| | Sphingobium sp. HT1-2 | GFF667 | | Hypothetical metal-binding enzyme, YcbL homolog | cofit | 36 | 25 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02154 | | Glyoxylase, beta-lactamase superfamily II | insig. | 34 | 35 |
| | Shewanella oneidensis MR-1 | SO3054 | | metallo-beta-lactamase family protein (NCBI ptt file) | sig. | 34 | 29 |
| | Caulobacter crescentus NA1000 | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 32 | 25 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 32 | 25 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS25095 | | MBL fold metallo-hydrolase | sig. | 31 | 35 |
| | Alteromonas macleodii MIT1002 | MIT1002_03450 | | Beta-lactamase hydrolase-like protein | insig. | 30 | 25 |
| | Methanococcus maripaludis S2 | MMP_RS00690 | | MBL fold metallo-hydrolase | insig. | 30 | 33 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS06505 | | MBL fold metallo-hydrolase | insig. | 35 | 30 |
| | Pseudomonas sp. BP01 | JOY50_RS07090 | gloB | hydroxyacylglutathione hydrolase | insig. | 31 | 25 |
| | Pseudomonas sp. S08-1 | OH686_03580 | | hydroxyacylglutathione hydrolase | cofit | 31 | 26 |
| | Pantoea sp. MT58 | IAI47_12770 | | MBL fold metallo-hydrolase | sig. | 30 | 40 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1061 | | hydroxyacylglutathione hydrolase | strong | 27 | 42 |
| | Rahnella sp. WP5 | EX31_RS18150 | | MBL fold metallo-hydrolase | insig. | 26 | 46 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03800 | | hydroxyacylglutathione hydrolase | strong | 30 | 27 |
| | Erwinia amylovora T8 | OLJFJH_16050 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 33 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06415 | | MBL fold metallo-hydrolase | insig. | 33 | 36 |
| | Acinetobacter radioresistens SK82 | MPMX26_00296 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 43 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.4979.1 | | Beta-lactamase related protein | insig. | 28 | 49 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3377 | | SoxH protein, homolog | insig. | 30 | 26 |
| | Erwinia tracheiphila SCR3 | LU632_RS09895 | | MBL fold metallo-hydrolase | insig. | 29 | 49 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS18785 | | MBL fold metallo-hydrolase | strong | 26 | 39 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2228 | | Zn-dependent hydrolases, including glyoxylases | insig. | 35 | 25 |
| | Pseudomonas putida KT2440 | PP_4144 | | Hydroxyacylglutathione hydrolase | sig. | 33 | 25 |
| | Sphingobium sp. HT1-2 | GFF4418 | | MBL-fold metallo-hydrolase superfamily | cofit | 32 | 34 |
| | Azospirillum sp. SherDot2 | MPMX19_04818 | | Hydroxyacylglutathione hydrolase GloC | insig. | 31 | 25 |
| | Serratia liquefaciens MT49 | IAI46_08745 | | MBL fold metallo-hydrolase | insig. | 27 | 48 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS35640 | | MBL fold metallo-hydrolase | insig. | 31 | 26 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS15105 | | MBL fold metallo-hydrolase | insig. | 26 | 39 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2009 | | Zn-dependent hydrolases, including glyoxylases | insig. | 29 | 37 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_20400 | | Hydroxyacylglutathione hydrolase GloC | cofit | 29 | 49 |
| | Enterobacter sp. TBS_079 | MPMX20_01585 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 37 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_18065 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 37 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS00825 | | MBL fold metallo-hydrolase | no data | 29 | 37 |
| | Azospirillum brasilense Sp245 | AZOBR_RS19250 | | hypothetical protein | no data | 29 | 25 |
| | Caulobacter crescentus NA1000 | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 27 | 40 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 27 | 40 |
| | Ralstonia solanacearum GMI1000 | RS_RS05710 | | MBL fold metallo-hydrolase | insig. | 29 | 39 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_08000 | gloB | hydroxyacylglutathione hydrolase | cofit | 27 | 43 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09160 | | MBL fold metallo-hydrolase | sig. | 26 | 46 |
| | Rhizobium sp. OAE497 | ABIE40_RS12965 | | MBL fold metallo-hydrolase | insig. | 31 | 32 |
| | Escherichia coli ECOR38 | HEPCGN_23135 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 30 | 36 |
| | Mycobacterium tuberculosis H37Rv | Rv2581c | | Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) | insig. | 24 | 50 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2517 | | beta-lactamase domain protein (RefSeq) | insig. | 25 | 43 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS14900 | | MBL fold metallo-hydrolase | no data | 30 | 39 |
| | Ralstonia solanacearum UW163 | UW163_RS12370 | | MBL fold metallo-hydrolase | insig. | 30 | 39 |
| | Mycobacterium tuberculosis H37Rv | Rv0634c | | Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) | insig. | 33 | 28 |
| | Pseudomonas protegens RBAN4 | FABNJH_07610 | | Beta-lactamase | insig. | 30 | 26 |
| | Klebsiella michiganensis M5al | BWI76_RS09865 | | MBL fold hydrolase | insig. | 29 | 37 |
| | Dickeya dianthicola 67-19 | HGI48_RS17040 | | MBL fold metallo-hydrolase | insig. | 28 | 43 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3246 | | Zn-dependent hydrolases, including glyoxylases | insig. | 28 | 26 |
| | Escherichia coli BL21 | ECD_00931 | | putative metal-binding enzyme | insig. | 26 | 42 |
| | Escherichia coli BW25113 | b0927 | ycbL | predicted metal-binding enzyme (NCBI) | sig. | 26 | 42 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS07420 | | MBL fold metallo-hydrolase | sig. | 39 | 20 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_04595 | | MBL fold metallo-hydrolase | insig. | 39 | 20 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS45370 | | MBL fold metallo-hydrolase | insig. | 39 | 20 |
| | Escherichia fergusonii Becca | EFB2_03137 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Escherichia coli ECOR27 | NOLOHH_21950 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Escherichia coli ECRC100 | OKFHMN_05390 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Escherichia coli ECRC101 | MCAODC_24780 | gloC | hydroxyacylglutathione hydrolase GloC | sig. | 29 | 36 |
| | Escherichia coli ECRC102 | NIAGMN_03110 | gloC | hydroxyacylglutathione hydrolase GloC | cofit | 29 | 36 |
| | Escherichia coli ECRC62 | BNILDI_20205 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Escherichia coli ECRC98 | JDDGAC_09000 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Escherichia coli ECRC99 | KEDOAH_22345 | gloC | hydroxyacylglutathione hydrolase GloC | no data | 29 | 36 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02740 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS04905 | | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 36 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1403 | | Hydroxyacylglutathione hydrolase | sig. | 28 | 32 |
| | Fusobacterium nucleatum SB010 | HUW76_04205 | | ribonuclease J | no data | 22 | 75 |
| | Xanthobacter sp. DMC5 | GFF4764 | | hypothetical protein | insig. | 36 | 23 |
| | Dickeya dianthicola ME23 | DZA65_RS18115 | | MBL fold metallo-hydrolase | insig. | 28 | 43 |
| | Shewanella loihica PV-4 | Shew_2269 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 30 | 31 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS18460 | | hypothetical protein | sig. | 29 | 39 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1871 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 28 | 35 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4505 | | Metal-dependent hydrolases of the beta-lactamase superfamily I | insig. | 27 | 32 |
| | Pseudomonas sp. BP01 | JOY50_RS13455 | gloB | hydroxyacylglutathione hydrolase | insig. | 33 | 25 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS15230 | | hydroxyacylglutathione hydrolase | insig. | 32 | 30 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS04590 | gloB;go_function=hydroxyacylglutathione | hydroxyacylglutathione hydrolase | insig. | 30 | 25 |
| | Serratia liquefaciens MT49 | IAI46_19930 | | MBL fold metallo-hydrolase | insig. | 29 | 30 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4920 | | hypothetical protein | insig. | 25 | 36 |
| | Xanthobacter sp. DMC5 | GFF2327 | | Hydroxyacylglutathione hydrolase GloB | insig. | 29 | 33 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00511 | | Phosphoribosyl 1,2-cyclic phosphodiesterase | insig. | 27 | 46 |
| | Dechlorosoma suillum PS | Dsui_3107 | | Zn-dependent hydrolase, glyoxylase | insig. | 31 | 25 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13516_RS15650 | gloB | hydroxyacylglutathione hydrolase | cofit | 30 | 37 |
| | Dickeya dadantii 3937 | DDA3937_RS16975 | | MBL fold metallo-hydrolase | insig. | 27 | 54 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11535 | | MBL fold metallo-hydrolase | insig. | 25 | 48 |
| | Rhodopseudomonas palustris CGA009 | TX73_002945 | | MBL fold metallo-hydrolase | insig. | 27 | 25 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS10505 | | MBL fold metallo-hydrolase | insig. | 31 | 23 |