Conservation of cofitness between PP_4782 and PP_0417 in Pseudomonas putida KT2440

73 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4782 Phosphomethylpyrimidine kinase 1.0 PP_0417 Anthranilate synthase component 1 0.57 12
Pseudomonas fluorescens SBW25 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.89 PFLU_RS27380 anthranilate synthase component I low > 109
Pseudomonas fluorescens SBW25-INTG 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.89 PFLU_RS27380 anthranilate synthase component I 0.31 68
Pseudomonas fluorescens FW300-N2C3 0.88 AO356_15435 hydrogenase 0.90 AO356_14420 anthranilate synthase low > 104
Pseudomonas simiae WCS417 0.87 PS417_24600 hydrogenase 0.89 PS417_25725 anthranilate synthase component I low > 88
Pseudomonas fluorescens FW300-N2E3 0.87 AO353_06350 hydrogenase 0.90 AO353_07230 anthranilate synthase low > 101
Pseudomonas fluorescens GW456-L13 0.87 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.88 PfGW456L13_1217 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.87 Psyr_4609 anthranilate synthase, component I low > 86
Pseudomonas syringae pv. syringae B728a 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.87 Psyr_4609 anthranilate synthase, component I low > 86
Pseudomonas sp. RS175 0.84 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.90 PFR28_04047 Anthranilate synthase component 1
Pseudomonas sp. S08-1 0.82 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD 0.85 OH686_15125 anthranilate synthase component I 0.73 8
Pseudomonas fluorescens FW300-N2E2 0.78 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.91 Pf6N2E2_4822 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 103
Pseudomonas fluorescens FW300-N1B4 0.78 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.90 Pf1N1B4_2545 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 87
Pseudomonas stutzeri RCH2 0.78 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.84 Psest_3650 anthranilate synthase component I, non-proteobacterial lineages low > 67
Dechlorosoma suillum PS 0.40 Dsui_0662 phosphomethylpyrimidine kinase 0.59 Dsui_0219 anthranilate synthase component I
Acinetobacter radioresistens SK82 0.38 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.50 MPMX26_00199 Anthranilate synthase component 1
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS02135 phosphomethylpyrimidine kinase 0.54 HSERO_RS19435 anthranilate synthase subunit I 0.37 49
Bacteroides thetaiotaomicron VPI-5482 0.29 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) 0.25 BT0532 anthranilate synthase component I (NCBI ptt file) low > 81
Phocaeicola dorei CL03T12C01 0.28 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 ABI39_RS21050 anthranilate synthase component I family protein 0.56 47
Phocaeicola vulgatus CL09T03C04 0.27 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 HMPREF1058_RS07175 anthranilate synthase component I family protein 0.81 13
Marinobacter adhaerens HP15 0.27 HP15_349 phosphomethylpyrimidine kinase 0.65 HP15_3288 anthranilate synthase component I
Rhodospirillum rubrum S1H 0.27 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) 0.41 Rru_A1891 Anthranilate synthase component I (NCBI)
Bacteroides ovatus ATCC 8483 0.26 BACOVA_02530 phosphomethylpyrimidine kinase 0.26 BACOVA_03780 chorismate binding enzyme 0.68 63
Ralstonia solanacearum UW163 0.26 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 UW163_RS07140 anthranilate synthase component I
Ralstonia solanacearum IBSBF1503 0.26 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 RALBFv3_RS06485 anthranilate synthase component I
Ralstonia solanacearum PSI07 0.26 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 RPSI07_RS10755 anthranilate synthase component I
Ralstonia solanacearum GMI1000 0.26 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 RS_RS14430 anthranilate synthase component I
Parabacteroides merdae CL09T00C40 0.26 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 HMPREF1078_RS00145 anthranilate synthase component I family protein low > 61
Bifidobacterium breve UCC2003 0.25 BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 BBR_RS16085 anthranilate synthase component I low > 34
Hydrogenophaga sp. GW460-11-11-14-LB1 0.24 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.53 GFF3106 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 90
Ralstonia sp. UNC404CL21Col 0.24 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 ABZR87_RS02140 anthranilate synthase component I
Mucilaginibacter yixingensis YX-36 DSM 26809 0.24 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 ABZR88_RS16595 anthranilate synthase component I family protein
Bosea sp. OAE506 0.24 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.39 ABIE41_RS15730 anthranilate synthase component I
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_0215 phosphomethylpyrimidine kinase 0.25 Echvi_2504 Anthranilate/para-aminobenzoate synthases component I low > 79
Bacteroides stercoris CC31F 0.24 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 HMPREF1181_RS15325 anthranilate synthase component I family protein low > 56
Brevundimonas sp. GW460-12-10-14-LB2 0.24 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.37 A4249_RS06155 anthranilate synthase component I
Escherichia coli BL21 0.24 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.25 ECD_01238 component I of anthranilate synthase low > 60
Escherichia coli ECRC101 0.24 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 OKFHMN_02655 trpE anthranilate synthase component I
Escherichia coli ECRC99 0.24 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 KEDOAH_26095 trpE anthranilate synthase component I
Escherichia coli ECRC98 0.24 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 JDDGAC_05200 trpE anthranilate synthase component I
Escherichia coli ECOR27 0.24 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 NOLOHH_20315 trpE anthranilate synthase component I low > 57
Escherichia coli ECRC102 0.24 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 NIAGMN_26825 trpE anthranilate synthase component I
Escherichia coli ECRC101 0.24 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 MCAODC_15610 trpE anthranilate synthase component I
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.25 OHPLBJKB_02419 Anthranilate synthase component 1 low > 73
Escherichia coli BW25113 0.24 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.25 b1264 trpE anthranilate synthase component I (NCBI) low > 76
Escherichia coli ECOR38 0.23 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 HEPCGN_25535 trpE anthranilate synthase component I low > 85
Lysobacter sp. OAE881 0.23 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 ABIE51_RS04150 anthranilate synthase component I
Escherichia coli Nissle 1917 0.23 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 ECOLIN_RS07615 anthranilate synthase component I
Xanthomonas campestris pv. campestris strain 8004 0.23 Xcc-8004.3091.1 hypothetical protein 0.56 Xcc-8004.608.1 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.71 19
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 ABZR86_RS12180 anthranilate synthase component I
Caulobacter crescentus NA1000 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.37 CCNA_01972 anthranilate synthase component I
Caulobacter crescentus NA1000 Δfur 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.37 CCNA_01972 anthranilate synthase component I
Azospirillum brasilense Sp245 0.23 AZOBR_RS07045 phosphomethylpyrimidine kinase 0.41 AZOBR_RS07490 anthranilate synthase subunit I
Paraburkholderia graminis OAS925 0.22 ABIE53_001125 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.53 ABIE53_003640 anthranilate synthase component 1 low > 113
Castellaniella sp019104865 MT123 0.22 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 ABCV34_RS10280 anthranilate synthase component I
Rhodanobacter sp. FW510-T8 0.22 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 OKGIIK_12405 trpE anthranilate synthase component I 0.57 4
Paraburkholderia bryophila 376MFSha3.1 0.22 H281DRAFT_04811 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.53 H281DRAFT_05715 anthranilate synthase, component I low > 103
Magnetospirillum magneticum AMB-1 0.22 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.41 AMB_RS09175 anthranilate synthase component I
Azospirillum sp. SherDot2 0.21 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.41 MPMX19_00893 Anthranilate synthase component 1
Acidovorax sp. GW101-3H11 0.21 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.54 Ac3H11_767 Anthranilate synthase, aminase component (EC 4.1.3.27)
Desulfovibrio vulgaris Hildenborough JW710 0.21 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) 0.28 DVU0465 trpE anthranilate synthase, component I (TIGR)
Sphingomonas koreensis DSMZ 15582 0.21 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.36 Ga0059261_0256 anthranilate synthase component I, non-proteobacterial lineages
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) 0.29 DvMF_1746 Anthranilate synthase (RefSeq)
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.25 CA264_05055 anthranilate synthase component I low > 74
Paraburkholderia sabiae LMG 24235 0.19 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 QEN71_RS27550 anthranilate synthase component I
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS04205 kinase 0.53 BPHYT_RS17390 anthranilate synthase subunit I low > 109
Pedobacter sp. GW460-11-11-14-LB5 0.19 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 CA265_RS22890 anthranilate synthase component I low > 88
Variovorax sp. OAS795 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 ABID97_RS05250 anthranilate synthase component I
Cupriavidus basilensis FW507-4G11 0.19 RR42_RS01370 phosphomethylpyrimidine kinase 0.53 RR42_RS18295 anthranilate synthase component I
Dinoroseobacter shibae DFL-12 0.18 Dshi_0915 phosphomethylpyrimidine kinase (RefSeq) 0.41 Dshi_1796 anthranilate synthase component I (RefSeq)
Mycobacterium tuberculosis H37Rv 0.18 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.37 Rv1609 Anthranilate synthase component I TrpE (glutamine amidotransferase)
Synechococcus elongatus PCC 7942 0.17 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase 0.39 Synpcc7942_1003 trpE anthranilate synthase, component I
Phaeobacter inhibens DSM 17395 0.17 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.39 PGA1_c16860 anthranilate synthase component 1
Variovorax sp. SCN45 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 GFF5896 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 127

Not shown: 20 genomes with orthologs for PP_4782 only; 7 genomes with orthologs for PP_0417 only