| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Pantoea sp. MT58 | 1.0 | IAI47_14515 | | multidrug efflux RND transporter permease subunit | 1.0 | IAI47_02465 | | metalloprotease TldD | 0.55 | 5 |
| Erwinia tracheiphila SCR3 | 0.87 | LU632_RS18185 | | efflux RND transporter permease subunit | 0.87 | LU632_RS21420 | tldD | metalloprotease TldD | — | — |
| Rahnella sp. WP5 | 0.82 | EX31_RS22470 | | multidrug efflux RND transporter permease subunit | 0.84 | EX31_RS12265 | | metalloprotease TldD | low | > 89 |
| Enterobacter asburiae PDN3 | 0.82 | EX28DRAFT_2496 | | The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family | 0.82 | EX28DRAFT_3295 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.71 | 26 |
| Klebsiella michiganensis M5al | 0.82 | BWI76_RS06775 | | multidrug efflux RND transporter permease subunit | 0.82 | BWI76_RS25470 | | metalloprotease TldD | low | > 92 |
| Enterobacter sp. TBS_079 | 0.81 | MPMX20_01064 | | Multidrug efflux pump subunit AcrB | 0.82 | MPMX20_04151 | | Metalloprotease TldD | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.81 | GFF4379 | | RND efflux system, inner membrane transporter CmeB | 0.83 | GFF2140 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 78 |
| Escherichia coli Nissle 1917 | 0.80 | ECOLIN_RS02750 | | efflux RND transporter permease AcrB | 0.82 | ECOLIN_RS18595 | | metalloprotease TldD | low | > 52 |
| Escherichia coli BW25113 | 0.80 | b0462 | acrB | multidrug efflux system protein (NCBI) | 0.82 | b3244 | tldD | predicted peptidase (NCBI) | low | > 76 |
| Escherichia coli ECRC62 | 0.80 | BNILDI_22555 | acrB | efflux RND transporter permease AcrB | 0.82 | BNILDI_01980 | tldD | metalloprotease TldD | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.80 | OHPLBJKB_03212 | | Multidrug efflux pump subunit AcrB | 0.82 | OHPLBJKB_00460 | | Metalloprotease TldD | low | > 73 |
| Escherichia coli ECOR38 | 0.80 | HEPCGN_06820 | acrB | efflux RND transporter permease AcrB | 0.82 | HEPCGN_16620 | tldD | metalloprotease TldD | low | > 85 |
| Escherichia fergusonii Becca | 0.80 | EFB2_03596 | | Multidrug efflux pump subunit AcrB | 0.82 | EFB2_00586 | | Metalloprotease TldD | low | > 86 |
| Escherichia coli ECOR27 | 0.80 | NOLOHH_01140 | acrB | efflux RND transporter permease AcrB | 0.82 | NOLOHH_09555 | tldD | metalloprotease TldD | low | > 57 |
| Escherichia coli BL21 | 0.80 | ECD_00413 | | multidrug efflux system protein | 0.82 | ECD_03104 | | putative peptidase | 0.61 | 52 |
| Escherichia coli ECRC101 | 0.80 | MCAODC_27430 | acrB | efflux RND transporter permease AcrB | 0.82 | MCAODC_08275 | tldD | metalloprotease TldD | — | — |
| Escherichia coli ECRC99 | 0.80 | KEDOAH_19760 | acrB | efflux RND transporter permease AcrB | 0.82 | KEDOAH_10395 | tldD | metalloprotease TldD | — | — |
| Escherichia coli ECRC102 | 0.80 | NIAGMN_06260 | acrB | efflux RND transporter permease AcrB | 0.82 | NIAGMN_15515 | tldD | metalloprotease TldD | — | — |
| Escherichia coli ECRC101 | 0.80 | OKFHMN_08205 | acrB | efflux RND transporter permease AcrB | 0.82 | OKFHMN_17755 | tldD | metalloprotease TldD | — | — |
| Dickeya dadantii 3937 | 0.79 | DDA3937_RS05735 | | multidrug efflux RND transporter permease subunit | 0.84 | DDA3937_RS01460 | | metalloprotease TldD | low | > 74 |
| Serratia liquefaciens MT49 | 0.78 | IAI46_05185 | | multidrug efflux RND transporter permease subunit SdeY | 0.84 | IAI46_22685 | | metalloprotease TldD | low | > 86 |
| Dickeya dianthicola ME23 | 0.77 | DZA65_RS06115 | | multidrug efflux RND transporter permease subunit | 0.83 | DZA65_RS01440 | | metalloprotease TldD | low | > 75 |
| Dickeya dianthicola 67-19 | 0.77 | HGI48_RS05790 | | multidrug efflux RND transporter permease subunit | 0.84 | HGI48_RS01380 | | metalloprotease TldD | low | > 71 |
| Pectobacterium carotovorum WPP14 | 0.77 | HER17_RS15740 | | multidrug efflux RND transporter permease subunit | 0.82 | HER17_RS20140 | | metalloprotease TldD | low | > 75 |
| Pseudomonas sp. S08-1 | 0.69 | OH686_16050 | | Multidrug efflux system, inner membrane proton/drug antiporter (RND type) | 0.61 | OH686_08580 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 80 |
| Escherichia coli ECRC98 | 0.69 | JDDGAC_19905 | mdtF | multidrug efflux pump RND permease MdtF | 0.82 | JDDGAC_21380 | tldD | metalloprotease TldD | — | — |
| Azospirillum brasilense Sp245 | 0.69 | AZOBR_RS30185 | | multidrug transporter | 0.48 | AZOBR_RS10600 | | peptidase C69 | low | > 97 |
| Pseudomonas fluorescens FW300-N2E2 | 0.69 | Pf6N2E2_2824 | | RND efflux system, inner membrane transporter CmeB | 0.61 | Pf6N2E2_3280 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.68 | AO356_04880 | | multidrug transporter | 0.61 | AO356_07095 | | protease TldD | low | > 104 |
| Pseudomonas sp. RS175 | 0.68 | PFR28_00631 | | putative efflux pump membrane transporter TtgB | 0.61 | PFR28_00161 | | Metalloprotease TldD | low | > 88 |
| Pseudomonas fluorescens FW300-N2E3 | 0.68 | AO353_17295 | | multidrug transporter | 0.62 | AO353_05215 | | protease TldD | low | > 101 |
| Pseudomonas putida KT2440 | 0.68 | PP_1385 | | Probable efflux pump membrane transporter TtgB | 0.64 | PP_0940 | | putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.68 | Pf1N1B4_3246 | | RND efflux system, inner membrane transporter CmeB | 0.61 | Pf1N1B4_1092 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 87 |
| Azospirillum sp. SherDot2 | 0.68 | MPMX19_05884 | | Multidrug efflux pump subunit AcrB | 0.48 | MPMX19_00882 | | Metalloprotease TldD | low | > 112 |
| Pseudomonas syringae pv. syringae B728a | 0.68 | Psyr_4008 | | Hydrophobe/amphiphile efflux-1 HAE1 | 0.64 | Psyr_4156 | | microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.68 | Psyr_4008 | | Hydrophobe/amphiphile efflux-1 HAE1 | 0.64 | Psyr_4156 | | microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 | — | — |
| Pseudomonas simiae WCS417 | 0.68 | PS417_06770 | | multidrug transporter | 0.62 | PS417_04285 | | protease TldD | low | > 88 |
| Pseudomonas fluorescens GW456-L13 | 0.67 | PfGW456L13_4581 | | RND efflux system, inner membrane transporter CmeB | 0.62 | PfGW456L13_5026 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 87 |
| Burkholderia phytofirmans PsJN | 0.67 | BPHYT_RS16170 | | multidrug efflux RND transporter permease subunit | 0.56 | BPHYT_RS03540 | | peptidase C69 | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.67 | QEN71_RS02525 | | efflux RND transporter permease subunit | 0.56 | QEN71_RS26555 | | metalloprotease TldD | 0.86 | 69 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.67 | H281DRAFT_04170 | | multidrug efflux pump | 0.56 | H281DRAFT_04688 | | microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.66 | ABIE53_003408 | | multidrug efflux pump | 0.56 | ABIE53_000851 | | TldD protein | low | > 113 |
| Shewanella oneidensis MR-1 | 0.66 | SO4692 | | AcrB/AcrD/AcrF family protein (NCBI ptt file) | 0.61 | SO4091 | tldD | tldD protein (NCBI ptt file) | low | > 76 |
| Pseudomonas fluorescens SBW25-INTG | 0.66 | PFLU_RS06805 | | efflux RND transporter permease subunit | 0.62 | PFLU_RS04340 | | metalloprotease TldD | 0.38 | 32 |
| Pseudomonas fluorescens SBW25 | 0.66 | PFLU_RS06805 | | efflux RND transporter permease subunit | 0.62 | PFLU_RS04340 | | metalloprotease TldD | low | > 109 |
| Shewanella sp. ANA-3 | 0.66 | Shewana3_4045 | | hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) | 0.64 | Shewana3_3641 | | microcin-processing peptidase 2 (RefSeq) | low | > 73 |
| Shewanella amazonensis SB2B | 0.66 | Sama_3554 | | AcrB/AcrD/AcrF family protein (RefSeq) | 0.62 | Sama_0474 | | TldD protein (RefSeq) | low | > 62 |
| Pseudomonas stutzeri RCH2 | 0.65 | Psest_0310 | | The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family | 0.62 | Psest_3320 | | Predicted Zn-dependent proteases and their inactivated homologs | low | > 67 |
| Shewanella loihica PV-4 | 0.65 | Shew_0032 | | hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) | 0.64 | Shew_0410 | | peptidase U62, modulator of DNA gyrase (RefSeq) | low | > 60 |
| Cupriavidus basilensis FW507-4G11 | 0.65 | RR42_RS32420 | | multidrug efflux RND transporter permease subunit | 0.57 | RR42_RS05875 | | protease TldD | low | > 128 |
| Rhodospirillum rubrum S1H | 0.65 | Rru_A2051 | | Hydrophobe/amphiphile efflux-1 HAE1 (NCBI) | 0.50 | Rru_A0567 | | Peptidase U62, modulator of DNA gyrase (NCBI) | low | > 58 |
| Ralstonia solanacearum PSI07 | 0.65 | RPSI07_RS03390 | | multidrug efflux RND transporter permease subunit | 0.57 | RPSI07_RS11850 | | metalloprotease TldD | low | > 81 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.64 | Xcc-8004.1794.1 | | RND efflux system, inner membrane transporter CmeB | 0.58 | Xcc-8004.1883.1 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 74 |
| Ralstonia solanacearum IBSBF1503 | 0.64 | RALBFv3_RS19795 | | multidrug efflux RND transporter permease subunit | 0.57 | RALBFv3_RS05455 | | metalloprotease TldD | low | > 76 |
| Ralstonia solanacearum UW163 | 0.64 | UW163_RS19380 | | multidrug efflux RND transporter permease subunit | 0.57 | UW163_RS08170 | | metalloprotease TldD | — | — |
| Ralstonia solanacearum GMI1000 | 0.64 | RS_RS21030 | | multidrug efflux RND transporter permease subunit | 0.57 | RS_RS13315 | | metalloprotease TldD | low | > 80 |
| Caulobacter crescentus NA1000 Δfur | 0.64 | CCNA_00850 | | cation/multidrug efflux pump acrB2 | 0.48 | CCNA_03522 | | Zn-dependent protease TldD | low | > 67 |
| Caulobacter crescentus NA1000 | 0.64 | CCNA_00850 | | cation/multidrug efflux pump acrB2 | 0.48 | CCNA_03522 | | Zn-dependent protease TldD | low | > 66 |
| Herbaspirillum seropedicae SmR1 | 0.64 | HSERO_RS06815 | | multidrug transporter | 0.56 | HSERO_RS07155 | | peptidase C69 | low | > 78 |
| Dyella japonica UNC79MFTsu3.2 | 0.62 | ABZR86_RS18285 | | efflux RND transporter permease subunit | 0.61 | ABZR86_RS21715 | | metalloprotease TldD | low | > 74 |
| Rhizobium sp. OAE497 | 0.60 | ABIE40_RS24225 | | efflux RND transporter permease subunit | 0.48 | ABIE40_RS04050 | | metalloprotease TldD | low | > 107 |
| Rhodopseudomonas palustris CGA009 | 0.57 | TX73_012255 | | efflux RND transporter permease subunit | 0.46 | TX73_004255 | | metalloprotease TldD | low | > 86 |
| Alteromonas macleodii MIT1002 | 0.57 | MIT1002_00135 | | Multidrug-efflux transporter MexB | 0.64 | MIT1002_00227 | | protease TldD | low | > 70 |
| Ralstonia sp. UNC404CL21Col | 0.55 | ABZR87_RS05315 | | efflux RND transporter permease subunit | 0.56 | ABZR87_RS01105 | | metalloprotease TldD | low | > 80 |
| Agrobacterium fabrum C58 | 0.54 | Atu2551 | | RND multidrug efflux transporter | 0.48 | Atu0765 | | TldD | low | > 89 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.53 | GFF3840 | | RND efflux system, inner membrane transporter CmeB | 0.56 | GFF580 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 90 |
| Variovorax sp. OAS795 | 0.52 | ABID97_RS00325 | | efflux RND transporter permease subunit | 0.56 | ABID97_RS06335 | | metalloprotease TldD | low | > 91 |
| Acidovorax sp. GW101-3H11 | 0.52 | Ac3H11_4448 | | RND efflux system, inner membrane transporter CmeB | 0.57 | Ac3H11_4036 | | TldD protein, part of TldE/TldD proteolytic complex | low | > 79 |
| Sinorhizobium meliloti 1021 | 0.50 | SMc02867 | | multidrug-efflux system transmembrane protein | 0.48 | SMc00960 | | hypothetical protein | low | > 103 |
| Lysobacter sp. OAE881 | 0.50 | ABIE51_RS17980 | | multidrug efflux RND transporter permease subunit | 0.59 | ABIE51_RS06795 | | metalloprotease TldD | low | > 62 |
| Castellaniella sp019104865 MT123 | 0.48 | ABCV34_RS04225 | | efflux RND transporter permease subunit | 0.57 | ABCV34_RS02590 | | metalloprotease TldD | low | > 48 |
| Rhodanobacter sp. FW510-T8 | 0.47 | OKGIIK_09170 | | Efflux pump membrane transporter | 0.60 | OKGIIK_10280 | tldD | metalloprotease TldD | low | > 52 |
| Rhodanobacter denitrificans FW104-10B01 | 0.46 | LRK54_RS02100 | | multidrug efflux RND transporter permease subunit | 0.59 | LRK54_RS03395 | | metalloprotease TldD | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.46 | LRK55_RS01875 | | multidrug efflux RND transporter permease subunit | 0.59 | LRK55_RS03145 | | metalloprotease TldD | low | > 63 |
| Kangiella aquimarina DSM 16071 | 0.46 | B158DRAFT_0733 | | The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family | 0.57 | B158DRAFT_2072 | | microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 | low | > 40 |
| Synechococcus elongatus PCC 7942 | 0.33 | Synpcc7942_2369 | acrF | Hydrophobe/amphiphile efflux-1 HAE1 | 0.23 | Synpcc7942_1127 | tldD | microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 | low | > 38 |
| Dinoroseobacter shibae DFL-12 | 0.13 | Dshi_0917 | | acriflavin resistance protein (RefSeq) | 0.44 | Dshi_1139 | | peptidase U62 modulator of DNA gyrase (RefSeq) | low | > 64 |
Not shown: 7 genomes with orthologs for IAI47_14515 only; 12 genomes with orthologs for IAI47_02465 only