Conservation of cofitness between PS417_20035 and PS417_04435 in Pseudomonas simiae WCS417

73 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_20035 adenosylcobinamide kinase 1.0 PS417_04435 uracil phosphoribosyltransferase 0.24 20
Pseudomonas fluorescens SBW25 0.91 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.98 PFLU_RS04485 uracil phosphoribosyltransferase low > 109
Pseudomonas fluorescens SBW25-INTG 0.91 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.98 PFLU_RS04485 uracil phosphoribosyltransferase low > 109
Pseudomonas sp. RS175 0.87 PFR28_03203 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.93 PFR28_03641 Uracil phosphoribosyltransferase low > 88
Pseudomonas fluorescens FW300-N2C3 0.87 AO356_19165 adenosylcobinamide kinase 0.93 AO356_16565 uracil phosphoribosyltransferase low > 104
Pseudomonas fluorescens FW300-N2E2 0.87 Pf6N2E2_5743 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.94 Pf6N2E2_5235 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.86 Psyr_3675 adenosylcobinamide kinase 0.94 Psyr_0969 uracil phosphoribosyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.86 Psyr_3675 adenosylcobinamide kinase 0.94 Psyr_0969 uracil phosphoribosyltransferase low > 86
Pseudomonas fluorescens FW300-N2E3 0.86 AO353_02610 adenosylcobinamide kinase 0.95 AO353_14855 uracil phosphoribosyltransferase low > 101
Pseudomonas fluorescens GW456-L13 0.85 PfGW456L13_4237 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.94 PfGW456L13_1597 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 87
Pseudomonas fluorescens FW300-N1B4 0.83 Pf1N1B4_3712 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.93 Pf1N1B4_2934 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 87
Pseudomonas putida KT2440 0.80 PP_1678 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase 0.93 PP_0746 Uracil phosphoribosyltransferase low > 96
Pseudomonas sp. S08-1 0.77 OH686_04960 Adenosylcobinamide kinase / Adenosylcobinamide-phosphate guanylyltransferase 0.92 OH686_17985 uracil phosphoribosyltransferase low > 80
Pseudomonas stutzeri RCH2 0.75 Psest_3007 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 0.90 Psest_1120 uracil phosphoribosyltransferase low > 67
Xanthomonas campestris pv. campestris strain 8004 0.64 Xcc-8004.1397.1 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.64 Xcc-8004.2160.1 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 74
Lysobacter sp. OAE881 0.63 ABIE51_RS04970 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.65 ABIE51_RS15050 uracil phosphoribosyltransferase low > 62
Rhodanobacter sp. FW510-T8 0.62 OKGIIK_05505 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.68 OKGIIK_10040 upp uracil phosphoribosyltransferase low > 52
Dyella japonica UNC79MFTsu3.2 0.61 ABZR86_RS10895 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.69 ABZR86_RS09615 uracil phosphoribosyltransferase low > 74
Acinetobacter radioresistens SK82 0.57 MPMX26_01613 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.78 MPMX26_02542 Uracil phosphoribosyltransferase — —
Dechlorosoma suillum PS 0.52 Dsui_0473 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 0.69 Dsui_2333 uracil phosphoribosyltransferase 0.60 12
Azospirillum sp. SherDot2 0.52 MPMX19_01023 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.47 MPMX19_02205 Uracil phosphoribosyltransferase — —
Ralstonia solanacearum UW163 0.49 UW163_RS09220 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.48 UW163_RS10140 uracil phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.49 RALBFv3_RS04450 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.48 RALBFv3_RS03530 uracil phosphoribosyltransferase low > 76
Ralstonia sp. UNC404CL21Col 0.48 ABZR87_RS00045 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.47 ABZR87_RS15395 uracil phosphoribosyltransferase low > 80
Ralstonia solanacearum GMI1000 0.48 RS_RS12005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.49 RS_RS10980 uracil phosphoribosyltransferase low > 80
Ralstonia solanacearum PSI07 0.48 RPSI07_RS12920 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.48 RPSI07_RS13695 uracil phosphoribosyltransferase low > 81
Shewanella amazonensis SB2B 0.47 Sama_0764 cobinamide kinase/cobinamide phosphate guanylyltransferase (RefSeq) 0.73 Sama_2096 upp uracil phosphoribosyltransferase (RefSeq) low > 62
Burkholderia phytofirmans PsJN 0.46 BPHYT_RS04895 adenosylcobinamide kinase 0.47 BPHYT_RS06415 uracil phosphoribosyltransferase low > 109
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS25100 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.48 QEN71_RS24390 uracil phosphoribosyltransferase low > 153
Paraburkholderia graminis OAS925 0.46 ABIE53_001254 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.46 ABIE53_001547 uracil phosphoribosyltransferase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_00145 adenosylcobinamide kinase /adenosylcobinamide-phosphate guanylyltransferase 0.46 H281DRAFT_04523 uracil phosphoribosyltransferase low > 103
Shewanella sp. ANA-3 0.45 Shewana3_3276 adenosylcobinamide kinase (RefSeq) 0.70 Shewana3_2544 upp uracil phosphoribosyltransferase (RefSeq) low > 73
Azospirillum brasilense Sp245 0.45 AZOBR_RS09835 adenosylcobinamide kinase 0.47 AZOBR_RS03150 uracil phosphoribosyltransferase — —
Bosea sp. OAE506 0.43 ABIE41_RS01770 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.53 ABIE41_RS22700 uracil phosphoribosyltransferase — —
Shewanella oneidensis MR-1 0.43 SO1037 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase (NCBI ptt file) 0.70 SO2759 upp uracil phosphoribosyltransferase (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.42 CSW01_06270 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.70 CSW01_11345 uracil phosphoribosyltransferase low > 62
Shewanella loihica PV-4 0.42 Shew_0716 cobalbumin biosynthesis enzyme (RefSeq) 0.70 Shew_1514 upp uracil phosphoribosyltransferase (RefSeq) low > 60
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF3979 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.51 GFF1179 Uracil phosphoribosyltransferase (EC 2.4.2.9) — —
Sinorhizobium meliloti 1021 0.41 SMc04305 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.51 SMc04121 uracil phosphoribosyltransferase — —
Agrobacterium fabrum C58 0.41 Atu1542 Bifunctional adenosylcobalamin biosynthesis protein cobP 0.50 Atu0135 uracil phosphoribosyltransferase low > 89
Dinoroseobacter shibae DFL-12 0.39 Dshi_2979 Adenosylcobinamide-phosphateguanylyltransferase (RefSeq) 0.53 Dshi_0831 uracil phosphoribosyltransferase (RefSeq) — —
Herbaspirillum seropedicae SmR1 0.38 HSERO_RS13245 adenosylcobinamide kinase 0.46 HSERO_RS03500 uracil phosphoribosyltransferase — —
Variovorax sp. SCN45 0.38 GFF448 Adenosylcobinamide kinase (EC 2.7.1.156) / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.50 GFF324 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 127
Rhodospirillum rubrum S1H 0.37 Rru_A0670 Cobalbumin biosynthesis enzyme (NCBI) 0.45 Rru_A2255 Uracil phosphoribosyl transferase (NCBI) low > 58
Rhizobium sp. OAE497 0.37 ABIE40_RS11165 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.50 ABIE40_RS00825 uracil phosphoribosyltransferase low > 107
Variovorax sp. OAS795 0.37 ABID97_RS17415 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.50 ABID97_RS16850 uracil phosphoribosyltransferase — —
Phaeobacter inhibens DSM 17395 0.36 PGA1_c26670 bifunctional adenosylcobalamin biosynthesis protein CobP 0.50 PGA1_c11960 uracil phosphoribosyltransferase Upp — —
Desulfovibrio vulgaris Hildenborough JW710 0.36 DVU1007 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase (TIGR) 0.63 DVU1025 upp uracil phosphoribosyltransferase (TIGR) — —
Rahnella sp. WP5 0.35 EX31_RS09935 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.71 EX31_RS22700 uracil phosphoribosyltransferase low > 89
Escherichia coli BL21 0.34 ECD_01902 cobinamide kinase and cobinamide phosphate guanylyltransferase 0.73 ECD_02390 uracil phosphoribosyltransferase — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_987 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.51 Ac3H11_2428 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 79
Escherichia coli ECRC98 0.34 JDDGAC_29255 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 JDDGAC_25760 upp uracil phosphoribosyltransferase — —
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS16460 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.23 ABI39_RS06680 uracil phosphoribosyltransferase low > 72
Escherichia coli BW25113 0.34 b1993 cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase (NCBI) 0.73 b2498 upp uracil phosphoribosyltransferase (VIMSS) low > 76
Escherichia coli Nissle 1917 0.34 ECOLIN_RS11630 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 ECOLIN_RS14185 uracil phosphoribosyltransferase — —
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS15650 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.22 HMPREF1181_RS01165 uracil phosphoribosyltransferase low > 56
Escherichia coli ECOR27 0.34 NOLOHH_16035 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 NOLOHH_13465 upp uracil phosphoribosyltransferase low > 57
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS01270 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.23 HMPREF1058_RS10070 uracil phosphoribosyltransferase low > 67
Escherichia coli ECRC102 0.34 NIAGMN_22630 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 NIAGMN_19585 upp uracil phosphoribosyltransferase — —
Escherichia fergusonii Becca 0.34 EFB2_01896 Bifunctional adenosylcobalamin biosynthesis protein CobU 0.73 EFB2_01400 Uracil phosphoribosyltransferase low > 86
Escherichia coli ECOR38 0.34 HEPCGN_03460 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 HEPCGN_20980 upp uracil phosphoribosyltransferase low > 85
Escherichia coli ECRC99 0.34 KEDOAH_02985 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 KEDOAH_06405 upp uracil phosphoribosyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.34 OHPLBJKB_01715 Bifunctional adenosylcobalamin biosynthesis protein CobU 0.73 OHPLBJKB_01228 Uracil phosphoribosyltransferase low > 73
Escherichia coli ECRC62 0.34 BNILDI_14865 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 BNILDI_12275 upp uracil phosphoribosyltransferase — —
Escherichia coli ECRC101 0.33 MCAODC_20265 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 MCAODC_12345 upp uracil phosphoribosyltransferase — —
Escherichia coli ECRC101 0.33 OKFHMN_25125 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.73 OKFHMN_21815 upp uracil phosphoribosyltransferase — —
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_0990 cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.37 Synpcc7942_1715 upp uracil phosphoribosyltransferase — —
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS17685 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.23 HMPREF1078_RS00655 uracil phosphoribosyltransferase low > 61
Klebsiella michiganensis M5al 0.32 BWI76_RS23005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.74 BWI76_RS20945 uracil phosphoribosyltransferase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF3967 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.73 GFF2171 Uracil phosphoribosyltransferase (EC 2.4.2.9) low > 78
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_3046 cobalbumin biosynthesis protein (RefSeq) 0.65 DvMF_0911 uracil phosphoribosyltransferase (RefSeq) low > 51
Echinicola vietnamensis KMM 6221, DSM 17526 0.29 Echvi_3757 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 0.23 Echvi_0597 Uracil phosphoribosyltransferase low > 79
Fusobacterium nucleatum SB010 0.28 HUW76_05615 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.52 HUW76_07615 uracil phosphoribosyltransferase — —
Mycobacterium tuberculosis H37Rv 0.25 Rv0254c Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanylyltransferase 0.38 Rv3309c Probable uracil phosphoribosyltransferase Upp (UMP pyrophosphorylase) (uprtase) (UMP diphosphorylase) — —

Not shown: 3 genomes with orthologs for PS417_20035 only; 25 genomes with orthologs for PS417_04435 only