| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 1.0 | GFF4099 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 1.0 | GFF5153 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.62 | 20 |
| Acidovorax sp. GW101-3H11 | 0.92 | Ac3H11_941 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.73 | Ac3H11_2922 | | Ribonucleotide reductase transcriptional regulator NrdR | — | — |
| Variovorax sp. OAS795 | 0.91 | ABID97_RS17550 | | fumarate hydratase | 0.77 | ABID97_RS17895 | | transcriptional regulator NrdR | low | > 91 |
| Variovorax sp. SCN45 | 0.91 | GFF483 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.77 | GFF561 | | Ribonucleotide reductase transcriptional regulator NrdR | low | > 127 |
| Herbaspirillum seropedicae SmR1 | 0.82 | HSERO_RS07760 | | fumarate hydratase | 0.67 | HSERO_RS06145 | | NrdR family transcriptional regulator | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.78 | RR42_RS13905 | | fumarate hydratase | 0.68 | RR42_RS15490 | | NrdR family transcriptional regulator | low | > 128 |
| Ralstonia solanacearum PSI07 | 0.78 | RPSI07_RS14865 | | fumarate hydratase | 0.68 | RPSI07_RS20335 | | transcriptional regulator NrdR | low | > 81 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.77 | H281DRAFT_04956 | | fumarase, class I, homodimeric | 0.56 | H281DRAFT_04727 | | transcriptional repressor NrdR | — | — |
| Burkholderia phytofirmans PsJN | 0.77 | BPHYT_RS06985 | | fumarate hydratase | 0.56 | BPHYT_RS03730 | | transcriptional repressor NrdR | low | > 109 |
| Paraburkholderia graminis OAS925 | 0.77 | ABIE53_001662 | | fumarate hydratase class I | 0.57 | ABIE53_000889 | | transcriptional repressor NrdR | low | > 113 |
| Ralstonia solanacearum GMI1000 | 0.77 | RS_RS09830 | | fumarate hydratase | 0.68 | RS_RS03665 | | transcriptional regulator NrdR | low | > 80 |
| Ralstonia sp. UNC404CL21Col | 0.77 | ABZR87_RS14375 | | fumarate hydratase | 0.68 | ABZR87_RS08950 | | transcriptional regulator NrdR | low | > 80 |
| Ralstonia solanacearum IBSBF1503 | 0.76 | RALBFv3_RS02460 | | fumarate hydratase | 0.68 | RALBFv3_RS12890 | | transcriptional regulator NrdR | low | > 76 |
| Ralstonia solanacearum UW163 | 0.76 | UW163_RS11265 | | fumarate hydratase | 0.68 | UW163_RS00675 | | transcriptional regulator NrdR | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.76 | QEN71_RS23780 | | fumarate hydratase | 0.56 | QEN71_RS26230 | | transcriptional regulator NrdR | low | > 153 |
| Dyella japonica UNC79MFTsu3.2 | 0.75 | ABZR86_RS19555 | | fumarate hydratase | 0.52 | ABZR86_RS10710 | | transcriptional regulator NrdR | low | > 74 |
| Rhodanobacter sp. FW510-T8 | 0.73 | OKGIIK_02115 | ttdA | fumarate hydratase | 0.52 | OKGIIK_11435 | nrdR | transcriptional regulator NrdR | low | > 52 |
| Rhodanobacter denitrificans MT42 | 0.73 | LRK55_RS12360 | | fumarate hydratase | 0.52 | LRK55_RS04390 | | transcriptional regulator NrdR | 0.69 | 58 |
| Lysobacter sp. OAE881 | 0.73 | ABIE51_RS12620 | | fumarate hydratase | 0.51 | ABIE51_RS04625 | | transcriptional regulator NrdR | — | — |
| Castellaniella sp019104865 MT123 | 0.73 | ABCV34_RS09450 | | fumarate hydratase | 0.55 | ABCV34_RS10550 | | transcriptional regulator NrdR | low | > 48 |
| Rhodanobacter denitrificans FW104-10B01 | 0.73 | LRK54_RS12620 | | fumarate hydratase | 0.52 | LRK54_RS04615 | | transcriptional regulator NrdR | low | > 59 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.72 | Xcc-8004.3506.1 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.52 | Xcc-8004.4397.1 | | Ribonucleotide reductase transcriptional regulator NrdR | — | — |
| Dechlorosoma suillum PS | 0.72 | Dsui_2001 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily,hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily | 0.64 | Dsui_1266 | | transcriptional regulator NrdR | — | — |
| Pseudomonas simiae WCS417 | 0.72 | PS417_22635 | | fumarate hydratase | 0.50 | PS417_25270 | | NrdR family transcriptional regulator | — | — |
| Pseudomonas fluorescens SBW25 | 0.71 | PFLU_RS24270 | | fumarate hydratase | 0.49 | PFLU_RS26905 | | transcriptional regulator NrdR | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.71 | Psyr_4031 | | fumarase | 0.50 | Psyr_4463 | | Protein of unknown function DUF193 | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.71 | PFLU_RS24270 | | fumarate hydratase | 0.49 | PFLU_RS26905 | | transcriptional regulator NrdR | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.71 | Psyr_4031 | | fumarase | 0.50 | Psyr_4463 | | Protein of unknown function DUF193 | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.71 | Pf1N1B4_683 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.50 | Pf1N1B4_2648 | | Ribonucleotide reductase transcriptional regulator NrdR | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.71 | PfGW456L13_1808 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.49 | PfGW456L13_1312 | | Ribonucleotide reductase transcriptional regulator NrdR | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.71 | AO353_03795 | | fumarate hydratase | 0.50 | AO353_06720 | | NrdR family transcriptional regulator | 0.27 | 74 |
| Pseudomonas stutzeri RCH2 | 0.71 | Psest_3193 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.49 | Psest_3553 | | transcriptional regulator NrdR | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.71 | AO356_17810 | | fumarate hydratase | 0.49 | AO356_14925 | | NrdR family transcriptional regulator | — | — |
| Pseudomonas putida KT2440 | 0.71 | PP_0897 | | Fumarate hydratase, class I | 0.50 | PP_0513 | | DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP | — | — |
| Pseudomonas sp. S08-1 | 0.70 | OH686_18780 | | Fumarate hydratase class I, aerobic | 0.48 | OH686_15690 | | transcriptional regulator NrdR | — | — |
| Acinetobacter radioresistens SK82 | 0.68 | MPMX26_00411 | | Fumarate hydratase class I, aerobic | 0.46 | MPMX26_00151 | | Transcriptional repressor NrdR | low | > 36 |
| Shewanella loihica PV-4 | 0.67 | Shew_1904 | | tartrate/fumarate subfamily Fe-S type hydro-lyase alpha subunit (RefSeq) | 0.47 | Shew_1186 | | transcriptional regulator NrdR (RefSeq) | — | — |
| Kangiella aquimarina DSM 16071 | 0.67 | B158DRAFT_1342 | | fumarase, class I, homodimeric (EC 4.2.1.2) | 0.49 | B158DRAFT_1909 | | transcriptional regulator NrdR | — | — |
| Marinobacter adhaerens HP15 | 0.67 | HP15_1143 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit | 0.54 | HP15_491 | | transcriptional repressor NrdR | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.67 | Ga0059261_3334 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.45 | Ga0059261_1985 | | transcriptional regulator NrdR | 0.45 | 35 |
| Shewanella amazonensis SB2B | 0.66 | Sama_1688 | | fumarate hydratase, class I, anaerobic, putative (RefSeq) | 0.48 | Sama_1015 | nrdR | transcriptional regulator NrdR (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.66 | SO2222 | | fumarate hydratase, class I, anaerobic, putative (NCBI ptt file) | 0.48 | SO3470 | | conserved hypothetical protein TIGR00244 (NCBI ptt file) | — | — |
| Alteromonas macleodii MIT1002 | 0.65 | MIT1002_02009 | | Fumarate hydratase class I, anaerobic | 0.48 | MIT1002_02701 | | Transcriptional repressor NrdR | — | — |
| Shewanella sp. ANA-3 | 0.65 | Shewana3_2302 | | fumarase (RefSeq) | 0.48 | Shewana3_1095 | nrdR | transcriptional regulator NrdR (RefSeq) | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.64 | CSW01_06585 | | fumarate hydratase | 0.48 | CSW01_11565 | | transcriptional regulator NrdR | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.55 | Dshi_1426 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (RefSeq) | 0.45 | Dshi_2257 | | ATP-cone domain protein (RefSeq) | — | — |
| Rhodopseudomonas palustris CGA009 | 0.21 | TX73_020085 | | fumarate hydratase | 0.42 | TX73_014120 | | transcriptional regulator NrdR | — | — |
| Enterobacter asburiae PDN3 | 0.20 | EX28DRAFT_1609 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.49 | EX28DRAFT_2557 | | transcriptional regulator NrdR | — | — |
| Escherichia coli ECRC62 | 0.20 | BNILDI_16940 | fumB | class I fumarate hydratase | 0.49 | BNILDI_22820 | nrdR | transcriptional regulator NrdR | — | — |
| Escherichia coli ECRC102 | 0.20 | NIAGMN_10370 | fumB | class I fumarate hydratase | 0.49 | NIAGMN_06515 | nrdR | transcriptional regulator NrdR | — | — |
| Escherichia coli ECOR38 | 0.20 | HEPCGN_06020 | fumB | class I fumarate hydratase | 0.49 | HEPCGN_07085 | nrdR | transcriptional regulator NrdR | low | > 85 |
| Escherichia coli BL21 | 0.20 | ECD_01581 | | fumarate hydratase (fumarase A), aerobic Class I | 0.49 | ECD_00361 | | Nrd regulon repressor | low | > 60 |
| Enterobacter sp. TBS_079 | 0.20 | MPMX20_02021 | | Fumarate hydratase class I, aerobic | 0.49 | MPMX20_01005 | | Transcriptional repressor NrdR | low | > 85 |
| Escherichia coli BW25113 | 0.20 | b1612 | fumA | fumarate hydratase (fumarase A), aerobic Class I (NCBI) | 0.49 | b0413 | ybaD | hypothetical protein (NCBI) | — | — |
| Magnetospirillum magneticum AMB-1 | 0.20 | AMB_RS06760 | | fumarate hydratase | 0.46 | AMB_RS11820 | | transcriptional regulator NrdR | — | — |
| Escherichia fergusonii Becca | 0.20 | EFB2_02380 | | Fumarate hydratase class I, aerobic | 0.49 | EFB2_03644 | | Transcriptional repressor NrdR | low | > 86 |
| Escherichia coli ECOR27 | 0.20 | NOLOHH_18150 | fumB | class I fumarate hydratase | 0.49 | NOLOHH_01405 | nrdR | transcriptional regulator NrdR | — | — |
| Escherichia coli Nissle 1917 | 0.20 | ECOLIN_RS09000 | | class I fumarate hydratase | 0.49 | ECOLIN_RS02500 | | transcriptional regulator NrdR | — | — |
| Escherichia coli ECRC101 | 0.20 | OKFHMN_12525 | fumB | class I fumarate hydratase | 0.49 | OKFHMN_08460 | nrdR | transcriptional regulator NrdR | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.20 | OHPLBJKB_03922 | | Fumarate hydratase class I, anaerobic | 0.49 | OHPLBJKB_03263 | | Transcriptional repressor NrdR | low | > 73 |
| Escherichia coli ECRC98 | 0.20 | JDDGAC_16160 | fumB | class I fumarate hydratase | 0.49 | JDDGAC_12115 | nrdR | transcriptional regulator NrdR | — | — |
| Escherichia coli ECRC99 | 0.20 | KEDOAH_15640 | fumB | class I fumarate hydratase | 0.49 | KEDOAH_19505 | nrdR | transcriptional regulator NrdR | — | — |
| Escherichia coli ECRC101 | 0.20 | MCAODC_03035 | fumB | class I fumarate hydratase | 0.49 | MCAODC_27685 | nrdR | transcriptional regulator NrdR | — | — |
| Rhizobium sp. OAE497 | 0.20 | ABIE40_RS10550 | | fumarate hydratase | 0.40 | ABIE40_RS06720 | | transcriptional regulator NrdR | low | > 107 |
| Rhodospirillum rubrum S1H | 0.19 | Rru_A2206 | | tartrate dehydrogenase (NCBI) | 0.42 | Rru_A1826 | | Protein of unknown function DUF193 (NCBI) | — | — |
| Serratia liquefaciens MT49 | 0.19 | IAI46_21370 | | fumarate hydratase | 0.49 | IAI46_04890 | | transcriptional regulator NrdR | low | > 86 |
| Klebsiella michiganensis M5al | 0.19 | BWI76_RS08450 | | fumarate hydratase | 0.48 | BWI76_RS06345 | | transcriptional regulator NrdR | — | — |
| Rahnella sp. WP5 | 0.19 | EX31_RS01160 | | fumarate hydratase | 0.49 | EX31_RS22120 | | transcriptional regulator NrdR | 0.48 | 22 |
| Azospirillum brasilense Sp245 | 0.19 | AZOBR_RS10315 | | fumarate hydratase | 0.44 | AZOBR_RS10020 | | NrdR family transcriptional regulator | — | — |
| Erwinia tracheiphila SCR3 | 0.19 | LU632_RS01205 | | class I fumarate hydratase FumA | 0.47 | LU632_RS18590 | nrdR | transcriptional regulator NrdR | low | > 74 |
| Azospirillum sp. SherDot2 | 0.19 | MPMX19_03166 | | Fumarate hydratase class I, aerobic | 0.42 | MPMX19_00728 | | Transcriptional repressor NrdR | — | — |
| Dickeya dianthicola ME23 | 0.19 | DZA65_RS04420 | | fumarate hydratase | 0.47 | DZA65_RS05885 | | transcriptional regulator NrdR | low | > 75 |
| Dickeya dadantii 3937 | 0.19 | DDA3937_RS04540 | | fumarate hydratase | 0.47 | DDA3937_RS05500 | | transcriptional regulator NrdR | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.18 | HER17_RS17120 | | fumarate hydratase | 0.46 | HER17_RS15965 | | transcriptional regulator NrdR | low | > 75 |
| Dickeya dianthicola 67-19 | 0.18 | HGI48_RS04500 | | fumarate hydratase | 0.47 | HGI48_RS05560 | | transcriptional regulator NrdR | low | > 71 |
| Pantoea sp. MT58 | 0.18 | IAI47_20435 | | fumarate hydratase | 0.48 | IAI47_14775 | | transcriptional regulator NrdR | low | > 76 |
| Bosea sp. OAE506 | 0.18 | ABIE41_RS00110 | | fumarate hydratase | 0.43 | ABIE41_RS19765 | | transcriptional regulator NrdR | — | — |
Not shown: 8 genomes with orthologs for GFF4099 only; 10 genomes with orthologs for GFF5153 only