Conservation of cofitness between PS417_23910 and PS417_23915 in Pseudomonas simiae WCS417

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_23910 3-methyl-2-oxobutanoate hydroxymethyltransferase 1.0 PS417_23915 pantoate--beta-alanine ligase 0.57 1
Pseudomonas fluorescens SBW25-INTG 0.98 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.98 PFLU_RS25755 pantoate--beta-alanine ligase low > 109
Pseudomonas fluorescens SBW25 0.98 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.98 PFLU_RS25755 pantoate--beta-alanine ligase 0.75 81
Pseudomonas fluorescens FW300-N2E3 0.89 AO353_14385 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.84 AO353_14380 pantoate--beta-alanine ligase 0.58 1
Pseudomonas fluorescens FW300-N2C3 0.87 AO356_16060 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.84 AO356_16055 pantoate--beta-alanine ligase — —
Pseudomonas fluorescens FW300-N1B4 0.87 Pf1N1B4_2854 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.85 Pf1N1B4_2853 Pantoate--beta-alanine ligase (EC 6.3.2.1) low > 87
Pseudomonas fluorescens FW300-N2E2 0.86 Pf6N2E2_5153 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.84 Pf6N2E2_5152 Pantoate--beta-alanine ligase (EC 6.3.2.1) — —
Pseudomonas fluorescens GW456-L13 0.86 PfGW456L13_1521 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.84 PfGW456L13_1520 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.57 1
Pseudomonas sp. RS175 0.85 PFR28_03721 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.84 PFR28_03722 Pantothenate synthetase — —
Pseudomonas putida KT2440 0.85 PP_4699 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.80 PP_4700 pantothenate synthetase 0.56 10
Pseudomonas syringae pv. syringae B728a ΔmexB 0.83 Psyr_0828 ketopantoate hydroxymethyltransferase 0.78 Psyr_0827 pantothenate synthetase low > 86
Pseudomonas syringae pv. syringae B728a 0.83 Psyr_0828 ketopantoate hydroxymethyltransferase 0.78 Psyr_0827 pantothenate synthetase — —
Pseudomonas sp. S08-1 0.80 OH686_17245 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.72 OH686_17240 pantoate--beta-alanine ligase — —
Pseudomonas stutzeri RCH2 0.75 Psest_0996 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.69 Psest_0995 pantoate--beta-alanine ligase — —
Marinobacter adhaerens HP15 0.61 HP15_324 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.62 HP15_323 pantothenate synthetase — —
Shewanella oneidensis MR-1 0.58 SO0870 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) 0.50 SO0869 panC pantoate--beta-alanine ligase (NCBI ptt file) — —
Escherichia coli ECRC62 0.58 BNILDI_08925 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 BNILDI_08920 panC pantoate--beta-alanine ligase — —
Shewanella amazonensis SB2B 0.58 Sama_0776 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) 0.51 Sama_0775 panC pantoate--beta-alanine ligase (RefSeq) — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.58 OHPLBJKB_03527 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 OHPLBJKB_03528 Pantothenate synthetase low > 73
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS05315 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.43 RALBFv3_RS04435 pantoate--beta-alanine ligase — —
Escherichia coli ECOR27 0.58 NOLOHH_02745 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 NOLOHH_02750 panC pantoate--beta-alanine ligase low > 57
Ralstonia solanacearum UW163 0.58 UW163_RS08310 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.43 UW163_RS09235 pantoate--beta-alanine ligase — —
Alteromonas macleodii MIT1002 0.57 MIT1002_03694 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.55 MIT1002_03695 Pantothenate synthetase — —
Shewanella sp. ANA-3 0.57 Shewana3_3408 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) 0.49 Shewana3_3409 panC pantoate--beta-alanine ligase (RefSeq) — —
Escherichia coli ECOR38 0.57 HEPCGN_08375 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 HEPCGN_08380 panC pantoate--beta-alanine ligase low > 85
Escherichia coli BW25113 0.57 b0134 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) 0.50 b0133 panC pantoate--beta-alanine ligase (NCBI) 0.79 1
Escherichia coli ECRC101 0.57 MCAODC_00915 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 MCAODC_00920 panC pantoate--beta-alanine ligase — —
Escherichia coli ECRC102 0.57 NIAGMN_08250 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 NIAGMN_08255 panC pantoate--beta-alanine ligase — —
Escherichia coli ECRC101 0.57 OKFHMN_10400 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 OKFHMN_10405 panC pantoate--beta-alanine ligase — —
Escherichia coli BL21 0.57 ECD_00133 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 ECD_00132 pantothenate synthetase low > 60
Escherichia coli ECRC98 0.57 JDDGAC_13995 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 JDDGAC_14000 panC pantoate--beta-alanine ligase — —
Shewanella loihica PV-4 0.57 Shew_3133 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) 0.51 Shew_3134 pantoate--beta-alanine ligase (RefSeq) — —
Escherichia fergusonii Becca 0.57 EFB2_03910 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 EFB2_03911 Pantothenate synthetase low > 86
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS03085 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.44 HSERO_RS15520 pantoate--beta-alanine ligase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS11985 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.42 RPSI07_RS12935 pantoate--beta-alanine ligase — —
Enterobacter sp. TBS_079 0.57 MPMX20_00827 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.46 MPMX20_00826 Pantothenate synthetase 0.25 3
Escherichia coli ECRC99 0.57 KEDOAH_17755 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 KEDOAH_17750 panC pantoate--beta-alanine ligase — —
Ralstonia solanacearum GMI1000 0.56 RS_RS13180 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.44 RS_RS11985 pantoate--beta-alanine ligase — —
Klebsiella michiganensis M5al 0.56 BWI76_RS04995 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 BWI76_RS04990 pantoate--beta-alanine ligase 0.70 1
Dickeya dianthicola 67-19 0.56 HGI48_RS16070 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.47 HGI48_RS16075 pantoate--beta-alanine ligase 0.94 4
Paraburkholderia sabiae LMG 24235 0.56 QEN71_RS26480 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.42 QEN71_RS25065 pantoate--beta-alanine ligase — —
Dickeya dadantii 3937 0.56 DDA3937_RS15955 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 DDA3937_RS15960 pantoate--beta-alanine ligase 0.97 2
Enterobacter asburiae PDN3 0.56 EX28DRAFT_3730 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.46 EX28DRAFT_3729 pantoate--beta-alanine ligase 0.85 2
Erwinia tracheiphila SCR3 0.56 LU632_RS20100 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 LU632_RS20105 panC pantoate--beta-alanine ligase 0.74 25
Dickeya dianthicola ME23 0.56 DZA65_RS17155 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.48 DZA65_RS17160 pantoate--beta-alanine ligase 0.95 4
Rahnella sp. WP5 0.56 EX31_RS03280 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.48 EX31_RS03285 pantoate--beta-alanine ligase low > 89
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_04703 ketopantoate hydroxymethyltransferase 0.41 H281DRAFT_00150 pantothenate synthetase — —
Paraburkholderia graminis OAS925 0.56 ABIE53_000867 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.42 ABIE53_001260 pantoate--beta-alanine ligase — —
Kangiella aquimarina DSM 16071 0.56 B158DRAFT_0061 ketopantoate hydroxymethyltransferase (EC 2.1.2.11) 0.51 B158DRAFT_0062 pantoate--beta-alanine ligase — —
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_03135 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 CSW01_03130 pantoate--beta-alanine ligase — —
Serratia liquefaciens MT49 0.55 IAI46_21240 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 IAI46_21245 pantoate--beta-alanine ligase low > 86
Pectobacterium carotovorum WPP14 0.55 HER17_RS05560 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 HER17_RS05555 pantoate--beta-alanine ligase 0.93 3
Pantoea sp. MT58 0.55 IAI47_15655 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.48 IAI47_15660 pantoate--beta-alanine ligase 0.54 7
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF91 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.50 GFF92 Pantoate--beta-alanine ligase (EC 6.3.2.1) low > 78
Burkholderia phytofirmans PsJN 0.54 BPHYT_RS03605 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.41 BPHYT_RS04925 pantothenate synthetase — —
Acinetobacter radioresistens SK82 0.54 MPMX26_00545 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 MPMX26_00546 Pantothenate synthetase — —
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS00950 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.42 ABZR87_RS00030 pantoate--beta-alanine ligase — —
Dechlorosoma suillum PS 0.52 Dsui_1471 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.46 Dsui_1470 pantoate--beta-alanine ligase — —
Lysobacter sp. OAE881 0.52 ABIE51_RS08025 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.48 ABIE51_RS08030 pantoate--beta-alanine ligase — —
Xanthomonas campestris pv. campestris strain 8004 0.50 Xcc-8004.3052.1 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.43 Xcc-8004.3051.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) — —
Rhodanobacter denitrificans MT42 0.49 LRK55_RS14830 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 LRK55_RS14835 pantoate--beta-alanine ligase 0.94 1
Hydrogenophaga sp. GW460-11-11-14-LB1 0.48 GFF1218 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.36 GFF1220 Pantoate--beta-alanine ligase (EC 6.3.2.1) — —
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS15115 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 LRK54_RS15120 pantoate--beta-alanine ligase — —
Acidovorax sp. GW101-3H11 0.48 Ac3H11_3839 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.36 Ac3H11_3840 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.64 53
Rhodanobacter sp. FW510-T8 0.47 OKGIIK_03885 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.48 OKGIIK_03890 panC pantoate--beta-alanine ligase 0.62 8
Cupriavidus basilensis FW507-4G11 0.46 RR42_RS17250 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.42 RR42_RS16055 pantothenate synthetase — —
Dyella japonica UNC79MFTsu3.2 0.46 ABZR86_RS00815 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 ABZR86_RS00820 pantoate--beta-alanine ligase — —
Variovorax sp. SCN45 0.45 GFF2579 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.43 GFF2578 Pantoate--beta-alanine ligase (EC 6.3.2.1) low > 127
Variovorax sp. OAS795 0.45 ABID97_RS07435 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.42 ABID97_RS07430 pantoate--beta-alanine ligase 0.89 1
Desulfovibrio vulgaris Miyazaki F 0.41 DvMF_2949 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) 0.38 DvMF_2942 panC pantoate--beta-alanine ligase (RefSeq) — —
Pedobacter sp. GW460-11-11-14-LB5 0.41 CA265_RS15235 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.36 CA265_RS22700 pantoate--beta-alanine ligase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.40 CA264_20605 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.36 CA264_17615 pantoate--beta-alanine ligase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS17835 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.39 ABZR88_RS18500 pantoate--beta-alanine ligase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.39 Echvi_1836 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.36 Echvi_1527 pantoate--beta-alanine ligase — —
Phocaeicola dorei CL03T12C01 0.38 ABI39_RS14025 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.37 ABI39_RS14555 pantoate--beta-alanine ligase — —
Phocaeicola vulgatus CL09T03C04 0.38 HMPREF1058_RS17810 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.37 HMPREF1058_RS18260 pantoate--beta-alanine ligase — —
Mycobacterium tuberculosis H37Rv 0.37 Rv2225 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB 0.33 Rv3602c Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) — —
Bacteroides stercoris CC31F 0.36 HMPREF1181_RS16225 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.40 HMPREF1181_RS06090 pantoate--beta-alanine ligase — —
Parabacteroides merdae CL09T00C40 0.34 HMPREF1078_RS09715 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.37 HMPREF1078_RS14680 pantoate--beta-alanine ligase 0.73 14
Bacteroides ovatus ATCC 8483 0.33 BACOVA_02402 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.39 BACOVA_05108 pantoate--beta-alanine ligase — —
Bacteroides thetaiotaomicron VPI-5482 0.32 BT0698 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) 0.39 BT4308 pantoate--beta-alanine ligase (NCBI ptt file) — —

Not shown: 1 genomes with orthologs for PS417_23910 only; 17 genomes with orthologs for PS417_23915 only