Conservation of cofitness between GFF2370 and GFF3455 in Sphingobium sp. HT1-2

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF2370 Anthranilate synthase, aminase component (EC 4.1.3.27) 1.0 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.91 14
Sphingomonas koreensis DSMZ 15582 0.72 Ga0059261_0256 anthranilate synthase component I, non-proteobacterial lineages 0.80 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.87 58
Magnetospirillum magneticum AMB-1 0.51 AMB_RS09175 anthranilate synthase component I 0.56 AMB_RS21365 O-succinylhomoserine sulfhydrylase
Rhodospirillum rubrum S1H 0.50 Rru_A1891 Anthranilate synthase component I (NCBI) 0.50 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) 0.51 41
Xanthobacter sp. DMC5 0.50 GFF950 Anthranilate synthase component 1 0.51 GFF4634 O-succinylhomoserine sulfhydrylase
Bosea sp. OAE506 0.49 ABIE41_RS15730 anthranilate synthase component I 0.50 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase
Azospirillum sp. SherDot2 0.49 MPMX19_00893 Anthranilate synthase component 1 0.47 MPMX19_01364 O-succinylhomoserine sulfhydrylase low > 112
Azospirillum brasilense Sp245 0.48 AZOBR_RS07490 anthranilate synthase subunit I 0.45 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase low > 97
Dinoroseobacter shibae DFL-12 0.45 Dshi_1796 anthranilate synthase component I (RefSeq) 0.47 Dshi_2410 O-succinylhomoserine sulfhydrylase (RefSeq)
Caulobacter crescentus NA1000 Δfur 0.45 CCNA_01972 anthranilate synthase component I 0.50 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Caulobacter crescentus NA1000 0.45 CCNA_01972 anthranilate synthase component I 0.50 CCNA_02321 O-succinylhomoserine sulfhydrylase 0.88 40
Phaeobacter inhibens DSM 17395 0.44 PGA1_c16860 anthranilate synthase component 1 0.48 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ
Brevundimonas sp. GW460-12-10-14-LB2 0.42 A4249_RS06155 anthranilate synthase component I 0.29 A4249_RS08315 cystathionine gamma-synthase low > 48
Marinobacter adhaerens HP15 0.38 HP15_3288 anthranilate synthase component I 0.36 HP15_1820 methionine gamma-lyase 0.85 16
Rhodanobacter denitrificans MT42 0.37 LRK55_RS11145 anthranilate synthase component I 0.28 LRK55_RS05410 cystathionine gamma-synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS11415 anthranilate synthase component I 0.27 LRK54_RS05660 PLP-dependent aspartate aminotransferase family protein low > 59
Methylophilus sp. DMC18 0.37 GFF2049 Anthranilate synthase component 1 0.41 GFF662 O-succinylhomoserine sulfhydrylase
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS12180 anthranilate synthase component I 0.29 ABZR86_RS18745 PLP-dependent aspartate aminotransferase family protein
Lysobacter sp. OAE881 0.36 ABIE51_RS04150 anthranilate synthase component I 0.30 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_12405 trpE anthranilate synthase component I 0.28 OKGIIK_01180 metC cystathionine beta-lyase low > 53
Rhodanobacter sp000427505 FW510-R12 0.36 LRK53_RS17085 anthranilate synthase component I 0.28 LRK53_RS04370 cystathionine gamma-synthase low > 59
Dechlorosoma suillum PS 0.36 Dsui_0219 anthranilate synthase component I 0.45 Dsui_3185 O-succinylhomoserine sulfhydrylase
Pseudomonas segetis P6 0.36 ACVTMO_RS04405 trpE anthranilate synthase component I 0.39 ACVTMO_RS15160 O-succinylhomoserine sulfhydrylase 0.76 16
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.608.1 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.31 Xcc-8004.1385.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 74
Acinetobacter baumannii LAC-4 0.36 RR41_RS17610 anthranilate synthase component I 0.42 RR41_RS12630 O-succinylhomoserine sulfhydrylase low > 55
Pseudomonas sp. S08-1 0.35 OH686_15125 anthranilate synthase component I 0.41 OH686_04415 O-succinylhomoserine sulfhydrylase 0.85 8
Pseudomonas sp. BP01 0.35 JOY50_RS18220 trpE anthranilate synthase component I 0.40 JOY50_RS16560 O-succinylhomoserine sulfhydrylase 0.51 29
Pseudomonas putida KT2440 0.35 PP_0417 Anthranilate synthase component 1 0.39 PP_2001 O-succinylhomoserine sulfhydrylase 0.92 7
Pseudomonas sp. RS175 0.35 PFR28_04047 Anthranilate synthase component 1 0.40 PFR28_02810 O-succinylhomoserine sulfhydrylase
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS18295 anthranilate synthase component I 0.44 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.82 12
Acidovorax sp. GW101-3H11 0.35 Ac3H11_767 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.32 Ac3H11_2928 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 79
Pseudomonas orientalis W4I3 0.35 QF045_RS00125 anthranilate synthase component I 0.32 QF045_RS17860 methionine gamma-lyase low > 93
Pseudomonas sp. SVBP6 0.35 COO64_RS22430 trpE anthranilate synthase component I 0.40 COO64_RS05595 O-succinylhomoserine sulfhydrylase 0.99 2
Pseudomonas stutzeri RCH2 0.35 Psest_3650 anthranilate synthase component I, non-proteobacterial lineages 0.39 Psest_2578 O-succinylhomoserine sulfhydrylase 0.86 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_4609 anthranilate synthase, component I 0.43 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.93 8
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_4609 anthranilate synthase, component I 0.43 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.94 1
Hydrogenophaga sp. GW460-11-11-14-LB1 0.35 GFF3106 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.46 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.90 13
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS02140 anthranilate synthase component I 0.33 ABZR87_RS13810 O-acetylhomoserine aminocarboxypropyltransferase low > 80
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4822 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.40 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 103
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_14420 anthranilate synthase 0.40 AO356_21470 O-succinylhomoserine sulfhydrylase 0.96 9
Ralstonia solanacearum PSI07 0.35 RPSI07_RS10755 anthranilate synthase component I 0.31 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase
Pseudomonas lactucae CFBP13502 0.35 GEMAOFIL_05265 Anthranilate synthase component 1 0.40 GEMAOFIL_03934 O-succinylhomoserine sulfhydrylase low > 96
Acinetobacter radioresistens SK82 0.35 MPMX26_00199 Anthranilate synthase component 1 0.42 MPMX26_01645 O-succinylhomoserine sulfhydrylase 0.92 26
Pseudomonas fluorescens SBW25 0.35 PFLU_RS27380 anthranilate synthase component I 0.41 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.47 88
Ralstonia solanacearum GMI1000 0.35 RS_RS14430 anthranilate synthase component I 0.31 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase low > 80
Pseudomonas fluorescens SBW25-INTG 0.35 PFLU_RS27380 anthranilate synthase component I 0.41 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.48 20
Ralstonia solanacearum UW163 0.34 UW163_RS07140 anthranilate synthase component I 0.31 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase
Ralstonia solanacearum IBSBF1503 0.34 RALBFv3_RS06485 anthranilate synthase component I 0.31 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase low > 76
Variovorax sp. SCN45 0.34 GFF5896 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.42 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_07230 anthranilate synthase 0.40 AO353_20695 O-succinylhomoserine sulfhydrylase 0.93 12
Pseudomonas simiae WCS417 0.34 PS417_25725 anthranilate synthase component I 0.40 PS417_18530 O-succinylhomoserine sulfhydrylase 0.93 6
Variovorax sp. OAS795 0.34 ABID97_RS05250 anthranilate synthase component I 0.42 ABID97_RS21630 O-succinylhomoserine sulfhydrylase
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_05715 anthranilate synthase, component I 0.46 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase 0.87 3
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS27550 anthranilate synthase component I 0.46 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Pseudomonas sp. DMC3 0.34 GFF20 Anthranilate synthase component 1 0.41 GFF799 O-succinylhomoserine sulfhydrylase 0.70 51
Pseudomonas aeruginosa PA14 0.34 IKLFDK_22365 anthranilate synthase component I 0.40 IKLFDK_15810 O-succinylhomoserine sulfhydrylase 0.84 14
Pseudomonas fluorescens GW456-L13 0.34 PfGW456L13_1217 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.40 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.88 13
Pseudomonas aeruginosa MRSN321 0.34 DY961_RS23075 trpE;go_function=anthranilate anthranilate synthase component I 0.40 DY961_RS01390 O-succinylhomoserine sulfhydrylase 0.87 5
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS17390 anthranilate synthase subunit I 0.47 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.94 7
Paraburkholderia graminis OAS925 0.34 ABIE53_003640 anthranilate synthase component 1 0.47 ABIE53_004817 O-succinylhomoserine sulfhydrylase 0.75 3
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS19435 anthranilate synthase subunit I 0.29 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase low > 78
Pseudomonas aeruginosa PUPa3 0.34 DQ20_RS36275 trpE;go_function=anthranilate anthranilate synthase component I 0.40 DQ20_RS34165 O-succinylhomoserine sulfhydrylase 0.87 1
Castellaniella sp019104865 MT123 0.33 ABCV34_RS10280 anthranilate synthase component I 0.31 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 48
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1003 trpE anthranilate synthase, component I 0.26 Synpcc7942_0370 metY O-acetylhomoserine/O-acetylserine sulfhydrylase
Mycobacterium tuberculosis H37Rv 0.31 Rv1609 Anthranilate synthase component I TrpE (glutamine amidotransferase) 0.44 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase)
Bifidobacterium breve UCC2003 0.29 BBR_RS16085 anthranilate synthase component I 0.30 BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 34
Bacteroides stercoris CC31F 0.27 HMPREF1181_RS15325 anthranilate synthase component I family protein 0.35 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 56
Parabacteroides merdae CL09T00C40 0.25 HMPREF1078_RS00145 anthranilate synthase component I family protein 0.29 HMPREF1078_RS07330 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 61
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS21050 anthranilate synthase component I family protein 0.36 ABI39_RS13825 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 72
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS07175 anthranilate synthase component I family protein 0.35 HMPREF1058_RS17635 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 67
Bacteroides ovatus ATCC 8483 0.25 BACOVA_03780 chorismate binding enzyme 0.36 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 96
Bacteroides thetaiotaomicron VPI-5482 0.25 BT0532 anthranilate synthase component I (NCBI ptt file) 0.36 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) low > 81
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_2504 Anthranilate/para-aminobenzoate synthases component I 0.41 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases 0.51 18
Cellulophaga baltica 18 0.23 M666_RS09090 anthranilate synthase component I family protein 0.40 M666_RS08150 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 67
Pedobacter sp. GW460-11-11-14-LB5 0.23 CA265_RS22890 anthranilate synthase component I 0.41 CA265_RS13080 O-succinylhomoserine sulfhydrylase 0.75 34
Pontibacter actiniarum KMM 6156, DSM 19842 0.22 CA264_05055 anthranilate synthase component I 0.40 CA264_02530 O-succinylhomoserine sulfhydrylase low > 74
Fusobacterium nucleatum SB010 0.22 HUW76_10205 aminodeoxychorismate synthase component I 0.36 HUW76_08240 methionine gamma-lyase low > 35

Not shown: 6 genomes with orthologs for GFF2370 only; 38 genomes with orthologs for GFF3455 only