| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF2370 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 1.0 | GFF3455 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.91 | 14 |
| Sphingomonas koreensis DSMZ 15582 | 0.72 | Ga0059261_0256 | | anthranilate synthase component I, non-proteobacterial lineages | 0.80 | Ga0059261_3194 | | O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) | 0.87 | 58 |
| Magnetospirillum magneticum AMB-1 | 0.51 | AMB_RS09175 | | anthranilate synthase component I | 0.56 | AMB_RS21365 | | O-succinylhomoserine sulfhydrylase | — | — |
| Rhodospirillum rubrum S1H | 0.50 | Rru_A1891 | | Anthranilate synthase component I (NCBI) | 0.50 | Rru_A3214 | | O-succinylhomoserine sulfhydrylase (NCBI) | 0.51 | 41 |
| Xanthobacter sp. DMC5 | 0.50 | GFF950 | | Anthranilate synthase component 1 | 0.51 | GFF4634 | | O-succinylhomoserine sulfhydrylase | — | — |
| Bosea sp. OAE506 | 0.49 | ABIE41_RS15730 | | anthranilate synthase component I | 0.50 | ABIE41_RS03970 | | O-succinylhomoserine sulfhydrylase | — | — |
| Azospirillum sp. SherDot2 | 0.49 | MPMX19_00893 | | Anthranilate synthase component 1 | 0.47 | MPMX19_01364 | | O-succinylhomoserine sulfhydrylase | low | > 112 |
| Azospirillum brasilense Sp245 | 0.48 | AZOBR_RS07490 | | anthranilate synthase subunit I | 0.45 | AZOBR_RS02140 | | O-succinylhomoserine sulfhydrylase | low | > 97 |
| Dinoroseobacter shibae DFL-12 | 0.45 | Dshi_1796 | | anthranilate synthase component I (RefSeq) | 0.47 | Dshi_2410 | | O-succinylhomoserine sulfhydrylase (RefSeq) | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.45 | CCNA_01972 | | anthranilate synthase component I | 0.50 | CCNA_02321 | | O-succinylhomoserine sulfhydrylase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.45 | CCNA_01972 | | anthranilate synthase component I | 0.50 | CCNA_02321 | | O-succinylhomoserine sulfhydrylase | 0.88 | 40 |
| Phaeobacter inhibens DSM 17395 | 0.44 | PGA1_c16860 | | anthranilate synthase component 1 | 0.48 | PGA1_c23540 | | O-succinylhomoserine sulfhydrylase MetZ | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.42 | A4249_RS06155 | | anthranilate synthase component I | 0.29 | A4249_RS08315 | | cystathionine gamma-synthase | low | > 48 |
| Marinobacter adhaerens HP15 | 0.38 | HP15_3288 | | anthranilate synthase component I | 0.36 | HP15_1820 | | methionine gamma-lyase | 0.85 | 16 |
| Rhodanobacter denitrificans MT42 | 0.37 | LRK55_RS11145 | | anthranilate synthase component I | 0.28 | LRK55_RS05410 | | cystathionine gamma-synthase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.37 | LRK54_RS11415 | | anthranilate synthase component I | 0.27 | LRK54_RS05660 | | PLP-dependent aspartate aminotransferase family protein | low | > 59 |
| Methylophilus sp. DMC18 | 0.37 | GFF2049 | | Anthranilate synthase component 1 | 0.41 | GFF662 | | O-succinylhomoserine sulfhydrylase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.37 | ABZR86_RS12180 | | anthranilate synthase component I | 0.29 | ABZR86_RS18745 | | PLP-dependent aspartate aminotransferase family protein | — | — |
| Lysobacter sp. OAE881 | 0.36 | ABIE51_RS04150 | | anthranilate synthase component I | 0.30 | ABIE51_RS04295 | | cystathionine gamma-synthase | low | > 62 |
| Rhodanobacter sp. FW510-T8 | 0.36 | OKGIIK_12405 | trpE | anthranilate synthase component I | 0.28 | OKGIIK_01180 | metC | cystathionine beta-lyase | low | > 53 |
| Rhodanobacter sp000427505 FW510-R12 | 0.36 | LRK53_RS17085 | | anthranilate synthase component I | 0.28 | LRK53_RS04370 | | cystathionine gamma-synthase | low | > 59 |
| Dechlorosoma suillum PS | 0.36 | Dsui_0219 | | anthranilate synthase component I | 0.45 | Dsui_3185 | | O-succinylhomoserine sulfhydrylase | — | — |
| Pseudomonas segetis P6 | 0.36 | ACVTMO_RS04405 | trpE | anthranilate synthase component I | 0.39 | ACVTMO_RS15160 | | O-succinylhomoserine sulfhydrylase | 0.76 | 16 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.36 | Xcc-8004.608.1 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.31 | Xcc-8004.1385.1 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | low | > 74 |
| Acinetobacter baumannii LAC-4 | 0.36 | RR41_RS17610 | | anthranilate synthase component I | 0.42 | RR41_RS12630 | | O-succinylhomoserine sulfhydrylase | low | > 55 |
| Pseudomonas sp. S08-1 | 0.35 | OH686_15125 | | anthranilate synthase component I | 0.41 | OH686_04415 | | O-succinylhomoserine sulfhydrylase | 0.85 | 8 |
| Pseudomonas sp. BP01 | 0.35 | JOY50_RS18220 | trpE | anthranilate synthase component I | 0.40 | JOY50_RS16560 | | O-succinylhomoserine sulfhydrylase | 0.51 | 29 |
| Pseudomonas putida KT2440 | 0.35 | PP_0417 | | Anthranilate synthase component 1 | 0.39 | PP_2001 | | O-succinylhomoserine sulfhydrylase | 0.92 | 7 |
| Pseudomonas sp. RS175 | 0.35 | PFR28_04047 | | Anthranilate synthase component 1 | 0.40 | PFR28_02810 | | O-succinylhomoserine sulfhydrylase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.35 | RR42_RS18295 | | anthranilate synthase component I | 0.44 | RR42_RS14320 | | O-succinylhomoserine sulfhydrylase | 0.82 | 12 |
| Acidovorax sp. GW101-3H11 | 0.35 | Ac3H11_767 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.32 | Ac3H11_2928 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | low | > 79 |
| Pseudomonas orientalis W4I3 | 0.35 | QF045_RS00125 | | anthranilate synthase component I | 0.32 | QF045_RS17860 | | methionine gamma-lyase | low | > 93 |
| Pseudomonas sp. SVBP6 | 0.35 | COO64_RS22430 | trpE | anthranilate synthase component I | 0.40 | COO64_RS05595 | | O-succinylhomoserine sulfhydrylase | 0.99 | 2 |
| Pseudomonas stutzeri RCH2 | 0.35 | Psest_3650 | | anthranilate synthase component I, non-proteobacterial lineages | 0.39 | Psest_2578 | | O-succinylhomoserine sulfhydrylase | 0.86 | 6 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.35 | Psyr_4609 | | anthranilate synthase, component I | 0.43 | Psyr_1669 | | O-succinylhomoserine sulfhydrylase | 0.93 | 8 |
| Pseudomonas syringae pv. syringae B728a | 0.35 | Psyr_4609 | | anthranilate synthase, component I | 0.43 | Psyr_1669 | | O-succinylhomoserine sulfhydrylase | 0.94 | 1 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.35 | GFF3106 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.46 | GFF301 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.90 | 13 |
| Ralstonia sp. UNC404CL21Col | 0.35 | ABZR87_RS02140 | | anthranilate synthase component I | 0.33 | ABZR87_RS13810 | | O-acetylhomoserine aminocarboxypropyltransferase | low | > 80 |
| Pseudomonas fluorescens FW300-N2E2 | 0.35 | Pf6N2E2_4822 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.40 | Pf6N2E2_77 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.35 | AO356_14420 | | anthranilate synthase | 0.40 | AO356_21470 | | O-succinylhomoserine sulfhydrylase | 0.96 | 9 |
| Ralstonia solanacearum PSI07 | 0.35 | RPSI07_RS10755 | | anthranilate synthase component I | 0.31 | RPSI07_RS15620 | | O-acetylhomoserine aminocarboxypropyltransferase | — | — |
| Pseudomonas lactucae CFBP13502 | 0.35 | GEMAOFIL_05265 | | Anthranilate synthase component 1 | 0.40 | GEMAOFIL_03934 | | O-succinylhomoserine sulfhydrylase | low | > 96 |
| Acinetobacter radioresistens SK82 | 0.35 | MPMX26_00199 | | Anthranilate synthase component 1 | 0.42 | MPMX26_01645 | | O-succinylhomoserine sulfhydrylase | 0.92 | 26 |
| Pseudomonas fluorescens SBW25 | 0.35 | PFLU_RS27380 | | anthranilate synthase component I | 0.41 | PFLU_RS20510 | | O-succinylhomoserine sulfhydrylase | 0.47 | 88 |
| Ralstonia solanacearum GMI1000 | 0.35 | RS_RS14430 | | anthranilate synthase component I | 0.31 | RS_RS07865 | | O-acetylhomoserine aminocarboxypropyltransferase | low | > 80 |
| Pseudomonas fluorescens SBW25-INTG | 0.35 | PFLU_RS27380 | | anthranilate synthase component I | 0.41 | PFLU_RS20510 | | O-succinylhomoserine sulfhydrylase | 0.48 | 20 |
| Ralstonia solanacearum UW163 | 0.34 | UW163_RS07140 | | anthranilate synthase component I | 0.31 | UW163_RS15180 | | O-acetylhomoserine aminocarboxypropyltransferase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.34 | RALBFv3_RS06485 | | anthranilate synthase component I | 0.31 | RALBFv3_RS01870 | | O-acetylhomoserine aminocarboxypropyltransferase | low | > 76 |
| Variovorax sp. SCN45 | 0.34 | GFF5896 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.42 | GFF3088 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.34 | AO353_07230 | | anthranilate synthase | 0.40 | AO353_20695 | | O-succinylhomoserine sulfhydrylase | 0.93 | 12 |
| Pseudomonas simiae WCS417 | 0.34 | PS417_25725 | | anthranilate synthase component I | 0.40 | PS417_18530 | | O-succinylhomoserine sulfhydrylase | 0.93 | 6 |
| Variovorax sp. OAS795 | 0.34 | ABID97_RS05250 | | anthranilate synthase component I | 0.42 | ABID97_RS21630 | | O-succinylhomoserine sulfhydrylase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.34 | H281DRAFT_05715 | | anthranilate synthase, component I | 0.46 | H281DRAFT_06059 | | O-succinylhomoserine sulfhydrylase | 0.87 | 3 |
| Paraburkholderia sabiae LMG 24235 | 0.34 | QEN71_RS27550 | | anthranilate synthase component I | 0.46 | QEN71_RS17685 | | O-succinylhomoserine sulfhydrylase | low | > 153 |
| Pseudomonas sp. DMC3 | 0.34 | GFF20 | | Anthranilate synthase component 1 | 0.41 | GFF799 | | O-succinylhomoserine sulfhydrylase | 0.70 | 51 |
| Pseudomonas aeruginosa PA14 | 0.34 | IKLFDK_22365 | | anthranilate synthase component I | 0.40 | IKLFDK_15810 | | O-succinylhomoserine sulfhydrylase | 0.84 | 14 |
| Pseudomonas fluorescens GW456-L13 | 0.34 | PfGW456L13_1217 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.40 | PfGW456L13_3934 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.88 | 13 |
| Pseudomonas aeruginosa MRSN321 | 0.34 | DY961_RS23075 | trpE;go_function=anthranilate | anthranilate synthase component I | 0.40 | DY961_RS01390 | | O-succinylhomoserine sulfhydrylase | 0.87 | 5 |
| Burkholderia phytofirmans PsJN | 0.34 | BPHYT_RS17390 | | anthranilate synthase subunit I | 0.47 | BPHYT_RS33835 | | O-succinylhomoserine sulfhydrylase | 0.94 | 7 |
| Paraburkholderia graminis OAS925 | 0.34 | ABIE53_003640 | | anthranilate synthase component 1 | 0.47 | ABIE53_004817 | | O-succinylhomoserine sulfhydrylase | 0.75 | 3 |
| Herbaspirillum seropedicae SmR1 | 0.34 | HSERO_RS19435 | | anthranilate synthase subunit I | 0.29 | HSERO_RS18310 | | O-acetylhomoserine aminocarboxypropyltransferase | low | > 78 |
| Pseudomonas aeruginosa PUPa3 | 0.34 | DQ20_RS36275 | trpE;go_function=anthranilate | anthranilate synthase component I | 0.40 | DQ20_RS34165 | | O-succinylhomoserine sulfhydrylase | 0.87 | 1 |
| Castellaniella sp019104865 MT123 | 0.33 | ABCV34_RS10280 | | anthranilate synthase component I | 0.31 | ABCV34_RS15785 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 48 |
| Synechococcus elongatus PCC 7942 | 0.33 | Synpcc7942_1003 | trpE | anthranilate synthase, component I | 0.26 | Synpcc7942_0370 | metY | O-acetylhomoserine/O-acetylserine sulfhydrylase | — | — |
| Mycobacterium tuberculosis H37Rv | 0.31 | Rv1609 | | Anthranilate synthase component I TrpE (glutamine amidotransferase) | 0.44 | Rv0391 | | Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) | — | — |
| Bifidobacterium breve UCC2003 | 0.29 | BBR_RS16085 | | anthranilate synthase component I | 0.30 | BBR_RS14595 | | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase | low | > 34 |
| Bacteroides stercoris CC31F | 0.27 | HMPREF1181_RS15325 | | anthranilate synthase component I family protein | 0.35 | HMPREF1181_RS05290 | | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase | low | > 56 |
| Parabacteroides merdae CL09T00C40 | 0.25 | HMPREF1078_RS00145 | | anthranilate synthase component I family protein | 0.29 | HMPREF1078_RS07330 | | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase | low | > 61 |
| Phocaeicola dorei CL03T12C01 | 0.25 | ABI39_RS21050 | | anthranilate synthase component I family protein | 0.36 | ABI39_RS13825 | | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase | low | > 72 |
| Phocaeicola vulgatus CL09T03C04 | 0.25 | HMPREF1058_RS07175 | | anthranilate synthase component I family protein | 0.35 | HMPREF1058_RS17635 | | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase | low | > 67 |
| Bacteroides ovatus ATCC 8483 | 0.25 | BACOVA_03780 | | chorismate binding enzyme | 0.36 | BACOVA_03030 | | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase | low | > 96 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.25 | BT0532 | | anthranilate synthase component I (NCBI ptt file) | 0.36 | BT2387 | | O-acetylhomoserine (thiol)-lyase (NCBI ptt file) | low | > 81 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.24 | Echvi_2504 | | Anthranilate/para-aminobenzoate synthases component I | 0.41 | Echvi_2283 | | Cystathionine beta-lyases/cystathionine gamma-synthases | 0.51 | 18 |
| Cellulophaga baltica 18 | 0.23 | M666_RS09090 | | anthranilate synthase component I family protein | 0.40 | M666_RS08150 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 67 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.23 | CA265_RS22890 | | anthranilate synthase component I | 0.41 | CA265_RS13080 | | O-succinylhomoserine sulfhydrylase | 0.75 | 34 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.22 | CA264_05055 | | anthranilate synthase component I | 0.40 | CA264_02530 | | O-succinylhomoserine sulfhydrylase | low | > 74 |
| Fusobacterium nucleatum SB010 | 0.22 | HUW76_10205 | | aminodeoxychorismate synthase component I | 0.36 | HUW76_08240 | | methionine gamma-lyase | low | > 35 |
Not shown: 6 genomes with orthologs for GFF2370 only; 38 genomes with orthologs for GFF3455 only