Conservation of cofitness between GFF4697 and GFF2307 in Variovorax sp. SCN45

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Variovorax sp. SCN45 1.0 GFF4697 TldE protein, part of TldE/TldD proteolytic complex 1.0 GFF2307 Heme O synthase, protoheme IX farnesyltransferase, COX10-CtaB 0.85 19
Variovorax sp. OAS795 0.96 ABID97_RS20695 metalloprotease PmbA 0.95 ABID97_RS23915 heme o synthase low > 91
Acidovorax sp. GW101-3H11 0.81 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex 0.83 Ac3H11_3883 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB
Hydrogenophaga sp. GW460-11-11-14-LB1 0.75 GFF3655 TldE protein, part of TldE/TldD proteolytic complex 0.81 GFF698 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB 0.66 11
Herbaspirillum seropedicae SmR1 0.62 HSERO_RS09265 peptidase C69 0.57 HSERO_RS20745 protoheme IX farnesyltransferase
Castellaniella sp019104865 MT123 0.60 ABCV34_RS10610 metalloprotease PmbA 0.54 ABCV34_RS13230 heme o synthase low > 48
Ralstonia solanacearum UW163 0.60 UW163_RS15845 metalloprotease PmbA 0.61 UW163_RS02590 protoheme IX farnesyltransferase
Ralstonia solanacearum IBSBF1503 0.60 RALBFv3_RS13965 metalloprotease PmbA 0.61 RALBFv3_RS10990 protoheme IX farnesyltransferase 0.64 56
Ralstonia solanacearum PSI07 0.59 RPSI07_RS19505 metalloprotease PmbA 0.61 RPSI07_RS22315 protoheme IX farnesyltransferase
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS09660 metalloprotease PmbA 0.60 ABZR87_RS06845 heme o synthase low > 80
Paraburkholderia graminis OAS925 0.59 ABIE53_003116 PmbA protein 0.59 ABIE53_000683 protoheme IX farnesyltransferase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_04304 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.61 H281DRAFT_01985 protoheme IX farnesyltransferase low > 103
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS14750 peptidase PMbA 0.61 RR42_RS01920 protoheme IX farnesyltransferase low > 128
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS04270 metalloprotease PmbA 0.61 QEN71_RS01545 heme o synthase low > 153
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS14705 peptidase C69 0.62 BPHYT_RS02690 protoheme IX farnesyltransferase low > 109
Ralstonia solanacearum GMI1000 0.57 RS_RS04700 metalloprotease PmbA 0.60 RS_RS01830 protoheme IX farnesyltransferase low > 80
Xanthomonas campestris pv. campestris strain 8004 0.46 Xcc-8004.1885.1 TldE protein, part of TldE/TldD proteolytic complex 0.43 Xcc-8004.4836.1 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA low > 74
Pseudomonas sp. RS175 0.46 PFR28_00163 Metalloprotease PmbA 0.44 PFR28_04683 Protoheme IX farnesyltransferase low > 88
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS21700 metalloprotease PmbA 0.44 ABZR86_RS12895 heme o synthase low > 74
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.44 Pf6N2E2_4106 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone low > 103
Pseudomonas fluorescens FW300-N2C3 0.45 AO356_07085 peptidase PmbA 0.44 AO356_11200 protoheme IX farnesyltransferase low > 104
Pectobacterium carotovorum WPP14 0.45 HER17_RS20090 metalloprotease PmbA 0.27 HER17_RS15895 heme o synthase low > 75
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS04350 metalloprotease PmbA 0.40 PFLU_RS00330 protoheme IX farnesyltransferase low > 109
Pseudomonas fluorescens SBW25 0.45 PFLU_RS04350 metalloprotease PmbA 0.40 PFLU_RS00330 protoheme IX farnesyltransferase low > 109
Enterobacter asburiae PDN3 0.45 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.26 EX28DRAFT_2543 protoheme IX farnesyltransferase low > 76
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_10260 pmbA metalloprotease PmbA 0.43 OKGIIK_16555 cyoE heme o synthase low > 52
Escherichia fergusonii Becca 0.45 EFB2_04298 Metalloprotease PmbA 0.27 EFB2_03629 Protoheme IX farnesyltransferase low > 86
Rahnella sp. WP5 0.45 EX31_RS12320 metalloprotease PmbA 0.26 EX31_RS22200 protoheme IX farnesyltransferase low > 89
Enterobacter sp. TBS_079 0.45 MPMX20_00517 Metalloprotease PmbA 0.26 MPMX20_01019 Protoheme IX farnesyltransferase 0.25 64
Escherichia coli ECRC98 0.45 JDDGAC_15565 pmbA metalloprotease PmbA 0.27 JDDGAC_12035 cyoE heme o synthase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.45 OHPLBJKB_03800 Metalloprotease PmbA 0.27 OHPLBJKB_03245 Protoheme IX farnesyltransferase low > 73
Escherichia coli BL21 0.45 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 0.27 ECD_00379 protoheme IX farnesyltransferase low > 61
Escherichia coli ECRC102 0.45 NIAGMN_09775 pmbA metalloprotease PmbA 0.27 NIAGMN_06435 cyoE heme o synthase
Escherichia coli ECOR27 0.45 NOLOHH_04185 pmbA metalloprotease PmbA 0.27 NOLOHH_01315 cyoE heme o synthase low > 75
Escherichia coli BW25113 0.45 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 0.27 b0428 cyoE protoheme IX farnesyltransferase (NCBI) low > 76
Escherichia coli ECRC62 0.45 BNILDI_07325 pmbA metalloprotease PmbA 0.27 BNILDI_22730 cyoE heme o synthase low > 75
Escherichia coli Nissle 1917 0.45 ECOLIN_RS24570 metalloprotease PmbA 0.27 ECOLIN_RS02575 heme o synthase low > 55
Alteromonas macleodii MIT1002 0.45 MIT1002_00230 peptidase PmbA 0.44 MIT1002_04027 Protoheme IX farnesyltransferase low > 70
Escherichia coli ECRC99 0.45 KEDOAH_16230 pmbA metalloprotease PmbA 0.27 KEDOAH_19585 cyoE heme o synthase
Escherichia coli ECOR38 0.45 HEPCGN_10125 pmbA metalloprotease PmbA 0.27 HEPCGN_06995 cyoE heme o synthase low > 87
Escherichia coli ECRC100 0.45 OKFHMN_11925 pmbA metalloprotease PmbA 0.27 OKFHMN_08380 cyoE heme o synthase low > 80
Escherichia coli ECRC101 0.45 MCAODC_02430 pmbA metalloprotease PmbA 0.27 MCAODC_27605 cyoE heme o synthase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.45 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.27 GFF4342 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB low > 78
Pseudomonas simiae WCS417 0.44 PS417_04295 peptidase PmbA 0.38 PS417_00340 protoheme IX farnesyltransferase low > 88
Pseudomonas putida KT2440 0.44 PP_0942 regulatory protease 0.38 PP_0110 CyoE like protoheme IX farnesyltransferase low > 96
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS03375 metalloprotease PmbA 0.44 LRK54_RS07085 heme o synthase low > 59
Serratia liquefaciens MT49 0.44 IAI46_22575 metalloprotease PmbA 0.26 IAI46_04965 protoheme IX farnesyltransferase low > 86
Rhodanobacter denitrificans MT42 0.44 LRK55_RS03125 metalloprotease PmbA 0.44 LRK55_RS06825 heme o synthase low > 63
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.45 Pf1N1B4_1862 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone low > 87
Pseudomonas sp. S08-1 0.44 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.40 OH686_12285 protoheme IX farnesyltransferase low > 80
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.24 Psyr_1145 Protoheme IX farnesyltransferase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.24 Psyr_1145 Protoheme IX farnesyltransferase
Pseudomonas fluorescens GW456-L13 0.44 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex 0.44 PfGW456L13_606 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone low > 87
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_05205 peptidase PmbA 0.43 AO353_10870 protoheme IX farnesyltransferase low > 101
Klebsiella michiganensis M5al 0.44 BWI76_RS02850 metalloprotease PmbA 0.27 BWI76_RS06475 protoheme IX farnesyltransferase low > 92
Pantoea sp. MT58 0.43 IAI47_02765 metalloprotease PmbA 0.27 IAI47_14700 protoheme IX farnesyltransferase low > 76
Dickeya dadantii 3937 0.43 DDA3937_RS01500 metalloprotease PmbA 0.27 DDA3937_RS05595 protoheme IX farnesyltransferase low > 74
Shewanella sp. ANA-3 0.43 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.44 Shewana3_3998 protoheme IX farnesyltransferase (RefSeq) low > 73
Dickeya dianthicola ME23 0.42 DZA65_RS01480 metalloprotease PmbA 0.26 DZA65_RS05965 protoheme IX farnesyltransferase low > 75
Dickeya dianthicola 67-19 0.42 HGI48_RS01415 metalloprotease PmbA 0.26 HGI48_RS05640 protoheme IX farnesyltransferase low > 71
Lysobacter sp. OAE881 0.42 ABIE51_RS06805 metalloprotease PmbA 0.46 ABIE51_RS19165 heme o synthase low > 62
Shewanella amazonensis SB2B 0.42 Sama_0482 PmbA protein (RefSeq) 0.38 Sama_3491 protoheme IX farnesyltransferase (RefSeq) low > 62
Erwinia tracheiphila SCR3 0.42 LU632_RS02145 pmbA metalloprotease PmbA 0.27 LU632_RS18395 cyoE heme o synthase
Shewanella oneidensis MR-1 0.42 SO4078 pmbA pmba protein (NCBI ptt file) 0.45 SO4614 ctaB protoheme IX farnesyltransferase (NCBI ptt file) low > 76
Pseudomonas stutzeri RCH2 0.42 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.43 Psest_4334 protoheme IX farnesyltransferase low > 67
Shewanella loihica PV-4 0.41 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.41 Shew_0117 protoheme IX farnesyltransferase (RefSeq) low > 60
Kangiella aquimarina DSM 16071 0.38 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.42 B158DRAFT_0671 protoheme IX farnesyltransferase low > 40
Azospirillum brasilense Sp245 0.33 AZOBR_RS11930 modulator protein 0.30 AZOBR_RS10580 protoheme IX farnesyltransferase low > 97
Azospirillum sp. SherDot2 0.30 MPMX19_01886 Metalloprotease PmbA 0.31 MPMX19_00886 Protoheme IX farnesyltransferase
Phaeobacter inhibens DSM 17395 0.30 PGA1_c33480 protein PmbA 0.29 PGA1_c06260 protoheme IX farnesyltransferase CtaB
Caulobacter crescentus NA1000 0.28 CCNA_00311 Zn-dependent protease family protein 0.31 CCNA_03516 protoheme IX farnesyltransferase coxE low > 66
Caulobacter crescentus NA1000 Δfur 0.28 CCNA_00311 Zn-dependent protease family protein 0.31 CCNA_03516 protoheme IX farnesyltransferase coxE low > 67
Sinorhizobium meliloti 1021 0.28 SMc00897 PMBA protein 0.32 SMc00450 protoheme IX farnesyltransferase low > 103
Sphingomonas koreensis DSMZ 15582 0.28 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs 0.31 Ga0059261_2005 protoheme IX farnesyltransferase low > 68
Magnetospirillum magneticum AMB-1 0.28 AMB_RS22120 TldD/PmbA family protein 0.20 AMB_RS03800 protoheme IX farnesyltransferase 1 low > 64
Dinoroseobacter shibae DFL-12 0.28 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) 0.31 Dshi_1141 protoheme IX farnesyltransferase (RefSeq) low > 64
Rhodopseudomonas palustris CGA009 0.27 TX73_005930 TldD/PmbA family protein 0.31 TX73_004295 heme o synthase low > 86
Brevundimonas sp. GW460-12-10-14-LB2 0.26 A4249_RS09195 TldD/PmbA family protein 0.34 A4249_RS00115 heme o synthase low > 48
Rhizobium sp. OAE497 0.26 ABIE40_RS03780 TldD/PmbA family protein 0.32 ABIE40_RS04070 heme o synthase low > 107
Agrobacterium fabrum C58 0.25 Atu0693 PmbA/TldD related protein 0.32 Atu0769 protoheme IX farnesyltransferase low > 89

Not shown: 7 genomes with orthologs for GFF4697 only; 8 genomes with orthologs for GFF2307 only