| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BL21 | 1.0 | ECD_04103 | | putative antibiotic peptide MccB17 maturation peptidase | 1.0 | ECD_02541 | | multidrug efflux system protein | 0.50 | 41 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_07325 | pmbA | metalloprotease PmbA | 1.00 | BNILDI_11175 | emrB | multidrug efflux MFS transporter permease subunit EmrB | low | > 75 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_02430 | pmbA | metalloprotease PmbA | 1.00 | MCAODC_11300 | emrB | multidrug efflux MFS transporter permease subunit EmrB | low | > 87 |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_10125 | pmbA | metalloprotease PmbA | 1.00 | HEPCGN_19970 | emrB | multidrug efflux MFS transporter permease subunit EmrB | low | > 87 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_03800 | | Metalloprotease PmbA | 1.00 | OHPLBJKB_01047 | | Multidrug export protein EmrB | low | > 73 |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_04185 | pmbA | metalloprotease PmbA | 1.00 | NOLOHH_12615 | emrB | multidrug efflux MFS transporter permease subunit EmrB | low | > 75 |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_09775 | pmbA | metalloprotease PmbA | 1.00 | NIAGMN_18545 | emrB | multidrug efflux MFS transporter permease subunit EmrB | — | — |
| Escherichia coli ECRC100 | 1.00 | OKFHMN_11925 | pmbA | metalloprotease PmbA | 1.00 | OKFHMN_20775 | emrB | multidrug efflux MFS transporter permease subunit EmrB | low | > 80 |
| Escherichia coli BW25113 | 1.00 | b4235 | pmbA | predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) | 1.00 | b2686 | emrB | multidrug efflux system protein (NCBI) | low | > 76 |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_16230 | pmbA | metalloprotease PmbA | 1.00 | KEDOAH_07360 | emrB | multidrug efflux MFS transporter permease subunit EmrB | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_15565 | pmbA | metalloprotease PmbA | 1.00 | JDDGAC_24440 | emrB | multidrug efflux MFS transporter permease subunit EmrB | 0.71 | 58 |
| Escherichia fergusonii Becca | 0.99 | EFB2_04298 | | Metalloprotease PmbA | 1.00 | EFB2_01242 | | Multidrug export protein EmrB | low | > 86 |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS24570 | | metalloprotease PmbA | 1.00 | ECOLIN_RS14970 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 55 |
| Enterobacter sp. TBS_079 | 0.96 | MPMX20_00517 | | Metalloprotease PmbA | 0.93 | MPMX20_03564 | | Multidrug export protein EmrB | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF904 | | TldE protein, part of TldE/TldD proteolytic complex | 0.95 | GFF1593 | | Multidrug resistance protein B | low | > 78 |
| Enterobacter asburiae PDN3 | 0.96 | EX28DRAFT_3422 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.93 | EX28DRAFT_2769 | | drug resistance transporter, EmrB/QacA subfamily | low | > 76 |
| Klebsiella michiganensis M5al | 0.94 | BWI76_RS02850 | | metalloprotease PmbA | 0.94 | BWI76_RS22100 | | multidrug effux MFS transporter subunit EmrB | low | > 92 |
| Serratia liquefaciens MT49 | 0.86 | IAI46_22575 | | metalloprotease PmbA | 0.82 | IAI46_20005 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 86 |
| Rahnella sp. WP5 | 0.85 | EX31_RS12320 | | metalloprotease PmbA | 0.85 | EX31_RS13660 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 89 |
| Pectobacterium carotovorum WPP14 | 0.84 | HER17_RS20090 | | metalloprotease PmbA | 0.83 | HER17_RS04460 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 75 |
| Pantoea sp. MT58 | 0.84 | IAI47_02765 | | metalloprotease PmbA | 0.88 | IAI47_04495 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 76 |
| Dickeya dadantii 3937 | 0.81 | DDA3937_RS01500 | | metalloprotease PmbA | 0.81 | DDA3937_RS16765 | | multidrug efflux MFS transporter permease subunit EmrB | 0.71 | 62 |
| Erwinia tracheiphila SCR3 | 0.81 | LU632_RS02145 | pmbA | metalloprotease PmbA | 0.32 | LU632_RS09490 | | DHA2 family efflux MFS transporter permease subunit | low | > 74 |
| Dickeya dianthicola ME23 | 0.81 | DZA65_RS01480 | | metalloprotease PmbA | 0.82 | DZA65_RS17910 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 75 |
| Dickeya dianthicola 67-19 | 0.81 | HGI48_RS01415 | | metalloprotease PmbA | 0.82 | HGI48_RS16835 | | multidrug efflux MFS transporter permease subunit EmrB | low | > 71 |
| Vibrio cholerae E7946 ATCC 55056 | 0.64 | CSW01_12845 | | metalloprotease PmbA | 0.39 | CSW01_07075 | | MFS transporter | low | > 62 |
| Shewanella amazonensis SB2B | 0.59 | Sama_0482 | | PmbA protein (RefSeq) | 0.23 | Sama_0403 | | drug resistance transporter, EmrB/QacA family protein (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_3631 | | microcin-processing peptidase 1 (RefSeq) | 0.29 | Shewana3_2224 | | EmrB/QacA family drug resistance transporter (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.59 | SO4078 | pmbA | pmba protein (NCBI ptt file) | 0.23 | SO0525 | | drug resistance transporter, EmrB/QacA family protein (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.57 | Shew_0416 | | peptidase U62, modulator of DNA gyrase (RefSeq) | 0.24 | Shew_3405 | | EmrB/QacA family drug resistance transporter (RefSeq) | low | > 60 |
| Pseudomonas sp. RS175 | 0.48 | PFR28_00163 | | Metalloprotease PmbA | 0.49 | PFR28_02747 | | Multidrug export protein EmrB | low | > 88 |
| Pseudomonas fluorescens SBW25 | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | 0.49 | PFLU_RS18895 | | DHA2 family efflux MFS transporter permease subunit | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.48 | Pf6N2E2_3278 | | TldE protein, part of TldE/TldD proteolytic complex | 0.48 | Pf6N2E2_149 | | Inner membrane component of tripartite multidrug resistance system | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.48 | AO356_07085 | | peptidase PmbA | 0.48 | AO356_01025 | | multidrug resistance protein B | low | > 104 |
| Pseudomonas fluorescens SBW25-INTG | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | 0.49 | PFLU_RS18895 | | DHA2 family efflux MFS transporter permease subunit | low | > 109 |
| Pseudomonas simiae WCS417 | 0.47 | PS417_04295 | | peptidase PmbA | 0.49 | PS417_16910 | | multidrug resistance protein B | low | > 88 |
| Pseudomonas putida KT2440 | 0.47 | PP_0942 | | regulatory protease | 0.49 | PP_3548 | | multidrug efflux transport system - permease subunit | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.47 | Pf1N1B4_1090 | | TldE protein, part of TldE/TldD proteolytic complex | 0.48 | Pf1N1B4_4002 | | Inner membrane component of tripartite multidrug resistance system | low | > 87 |
| Pseudomonas fluorescens GW456-L13 | 0.47 | PfGW456L13_5024 | | TldE protein, part of TldE/TldD proteolytic complex | 0.49 | PfGW456L13_2606 | | Inner membrane component of tripartite multidrug resistance system | low | > 87 |
| Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_05205 | | peptidase PmbA | 0.49 | AO353_27840 | | multidrug resistance protein B | low | > 101 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.46 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | 0.48 | Psyr_1731 | | Drug resistance transporter EmrB/QacA subfamily | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.46 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | 0.48 | Psyr_1731 | | Drug resistance transporter EmrB/QacA subfamily | low | > 86 |
| Herbaspirillum seropedicae SmR1 | 0.45 | HSERO_RS09265 | | peptidase C69 | 0.50 | HSERO_RS13575 | | DSBA oxidoreductase | low | > 78 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.45 | Xcc-8004.1885.1 | | TldE protein, part of TldE/TldD proteolytic complex | 0.45 | Xcc-8004.3524.1 | | Inner membrane component of tripartite multidrug resistance system | low | > 74 |
| Variovorax sp. OAS795 | 0.45 | ABID97_RS20695 | | metalloprotease PmbA | 0.50 | ABID97_RS20390 | | DHA2 family efflux MFS transporter permease subunit | low | > 91 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS21700 | | metalloprotease PmbA | 0.49 | ABZR86_RS14765 | | DHA2 family efflux MFS transporter permease subunit | low | > 74 |
| Pseudomonas sp. S08-1 | 0.45 | OH686_08570 | | TldE protein, part of TldE/TldD proteolytic complex | 0.23 | OH686_04570 | | Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system | low | > 80 |
| Rhodanobacter sp. FW510-T8 | 0.45 | OKGIIK_10260 | pmbA | metalloprotease PmbA | 0.49 | OKGIIK_08535 | emrB | MFS transporter | low | > 52 |
| Variovorax sp. SCN45 | 0.45 | GFF4697 | | TldE protein, part of TldE/TldD proteolytic complex | 0.51 | GFF4771 | | Multidrug efflux system EmrAB-OMF, inner-membrane proton/drug antiporter EmrB (MFS type) | low | > 127 |
| Rhodanobacter denitrificans MT42 | 0.44 | LRK55_RS03125 | | metalloprotease PmbA | 0.51 | LRK55_RS15865 | | DHA2 family efflux MFS transporter permease subunit | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.44 | LRK54_RS03375 | | metalloprotease PmbA | 0.51 | LRK54_RS16115 | | DHA2 family efflux MFS transporter permease subunit | low | > 59 |
| Dechlorosoma suillum PS | 0.44 | Dsui_1234 | | putative Zn-dependent protease-like protein | 0.13 | Dsui_1523 | | drug resistance transporter, EmrB/QacA subfamily | low | > 51 |
| Acidovorax sp. GW101-3H11 | 0.44 | Ac3H11_3262 | | TldE protein, part of TldE/TldD proteolytic complex | 0.49 | Ac3H11_2352 | | Inner membrane component of tripartite multidrug resistance system | low | > 79 |
| Ralstonia solanacearum UW163 | 0.43 | UW163_RS15845 | | metalloprotease PmbA | 0.18 | UW163_RS07870 | | MFS transporter | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.43 | RALBFv3_RS13965 | | metalloprotease PmbA | 0.54 | RALBFv3_RS15695 | | MFS transporter | low | > 76 |
| Ralstonia sp. UNC404CL21Col | 0.43 | ABZR87_RS09660 | | metalloprotease PmbA | 0.55 | ABZR87_RS11225 | | DHA2 family efflux MFS transporter permease subunit | low | > 80 |
| Paraburkholderia graminis OAS925 | 0.43 | ABIE53_003116 | | PmbA protein | 0.53 | ABIE53_000311 | | DHA2 family multidrug resistance protein | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_04304 | | microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 | 0.54 | H281DRAFT_02341 | | MFS transporter, DHA2 family, multidrug resistance protein | low | > 103 |
| Ralstonia solanacearum PSI07 | 0.43 | RPSI07_RS19505 | | metalloprotease PmbA | 0.53 | RPSI07_RS17660 | | MFS transporter | low | > 81 |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS14705 | | peptidase C69 | 0.54 | BPHYT_RS19670 | | DSBA oxidoreductase | low | > 109 |
| Paraburkholderia sabiae LMG 24235 | 0.43 | QEN71_RS04270 | | metalloprotease PmbA | 0.52 | QEN71_RS23085 | | DHA2 family efflux MFS transporter permease subunit | low | > 153 |
| Castellaniella sp019104865 MT123 | 0.42 | ABCV34_RS10610 | | metalloprotease PmbA | 0.51 | ABCV34_RS05950 | | DHA2 family efflux MFS transporter permease subunit | low | > 48 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.41 | GFF3655 | | TldE protein, part of TldE/TldD proteolytic complex | 0.53 | GFF3757 | | Inner membrane component of tripartite multidrug resistance system | low | > 90 |
| Lysobacter sp. OAE881 | 0.41 | ABIE51_RS06805 | | metalloprotease PmbA | 0.49 | ABIE51_RS07705 | | DHA2 family efflux MFS transporter permease subunit | low | > 62 |
| Ralstonia solanacearum GMI1000 | 0.41 | RS_RS04700 | | metalloprotease PmbA | 0.54 | RS_RS06475 | | MFS transporter | low | > 80 |
| Cupriavidus basilensis FW507-4G11 | 0.41 | RR42_RS14750 | | peptidase PMbA | 0.51 | RR42_RS12830 | | multidrug resistance protein B | low | > 128 |
| Azospirillum sp. SherDot2 | 0.34 | MPMX19_01886 | | Metalloprotease PmbA | 0.30 | MPMX19_04034 | | Multidrug export protein EmrB | low | > 112 |
| Sphingomonas koreensis DSMZ 15582 | 0.30 | Ga0059261_0810 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.29 | Ga0059261_4005 | | drug resistance transporter, EmrB/QacA subfamily | low | > 68 |
| Magnetospirillum magneticum AMB-1 | 0.29 | AMB_RS22120 | | TldD/PmbA family protein | 0.22 | AMB_RS20240 | | MFS transporter | low | > 64 |
| Rhodopseudomonas palustris CGA009 | 0.29 | TX73_005930 | | TldD/PmbA family protein | 0.41 | TX73_019160 | | DHA2 family efflux MFS transporter permease subunit | low | > 86 |
| Rhodospirillum rubrum S1H | 0.29 | Rru_A0575 | | Peptidase U62, modulator of DNA gyrase (NCBI) | 0.50 | Rru_A0858 | | Drug resistance transporter EmrB/QacA subfamily (NCBI) | low | > 58 |
| Caulobacter crescentus NA1000 | 0.28 | CCNA_00311 | | Zn-dependent protease family protein | 0.21 | CCNA_03831 | | major facilitator superfamily transporter | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.28 | CCNA_00311 | | Zn-dependent protease family protein | 0.21 | CCNA_03831 | | major facilitator superfamily transporter | low | > 67 |
| Sinorhizobium meliloti 1021 | 0.28 | SMc00897 | | PMBA protein | 0.20 | SMc03167 | | multidrug efflux system protein | low | > 103 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.28 | A4249_RS09195 | | TldD/PmbA family protein | 0.22 | A4249_RS14985 | | DHA2 family efflux MFS transporter permease subunit | low | > 48 |
| Agrobacterium fabrum C58 | 0.27 | Atu0693 | | PmbA/TldD related protein | 0.23 | Atu4479 | | MFS permease | low | > 89 |
| Rhizobium sp. OAE497 | 0.27 | ABIE40_RS03780 | | TldD/PmbA family protein | 0.30 | ABIE40_RS21925 | | DHA2 family efflux MFS transporter permease subunit | low | > 107 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.06 | CA265_RS02445 | | peptidase C69 | 0.27 | CA265_RS21345 | | MFS transporter | low | > 88 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.06 | CA264_16645 | | peptidase C69 | 0.28 | CA264_07170 | | MFS transporter | low | > 74 |
Not shown: 10 genomes with orthologs for ECD_04103 only; 6 genomes with orthologs for ECD_02541 only