Conservation of cofitness between CSW01_19520 and CSW01_18565 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_19520 chemotaxis response regulator protein-glutamate methylesterase 1.0 CSW01_18565 L-threonine 3-dehydrogenase 0.48 11
Shewanella loihica PV-4 0.48 Shew_0109 response regulator receiver modulated CheB methylesterase (RefSeq) 0.88 Shew_3710 tdh L-threonine 3-dehydrogenase (RefSeq) low > 60
Xanthomonas campestris pv. campestris strain 8004 0.46 Xcc-8004.2888.1 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) 0.64 Xcc-8004.4082.1 L-threonine 3-dehydrogenase (EC 1.1.1.103) low > 74
Dyella japonica UNC79MFTsu3.2 0.46 ABZR86_RS22205 chemotaxis response regulator protein-glutamate methylesterase 0.66 ABZR86_RS08385 L-threonine 3-dehydrogenase low > 74
Lysobacter sp. OAE881 0.46 ABIE51_RS16960 chemotaxis response regulator protein-glutamate methylesterase 0.64 ABIE51_RS06140 L-threonine 3-dehydrogenase low > 62
Erwinia tracheiphila SCR3 0.45 LU632_RS13525 chemotaxis response regulator protein-glutamate methylesterase 0.17 LU632_RS00630 adhP alcohol dehydrogenase AdhP low > 73
Serratia liquefaciens MT49 0.45 IAI46_16015 chemotaxis response regulator protein-glutamate methylesterase 0.88 IAI46_24725 L-threonine 3-dehydrogenase low > 87
Erwinia tracheiphila HP pepo 2.2 0.45 IJEDHG_22020 cheB chemotaxis response regulator protein-glutamate methylesterase 0.17 IJEDHG_10510 adhP alcohol dehydrogenase AdhP low > 61
Rahnella sp. WP5 0.45 EX31_RS11360 chemotaxis response regulator protein-glutamate methylesterase 0.88 EX31_RS14385 L-threonine 3-dehydrogenase low > 89
Dickeya dadantii 3937 0.45 DDA3937_RS13525 chemotaxis response regulator protein-glutamate methylesterase 0.83 DDA3937_RS20430 L-threonine 3-dehydrogenase low > 74
Shewanella amazonensis SB2B 0.45 Sama_3499 protein-glutamate methylesterase (RefSeq) 0.89 Sama_0097 tdh L-threonine 3-dehydrogenase (RefSeq) low > 62
Dickeya dianthicola ME23 0.45 DZA65_RS14055 chemotaxis response regulator protein-glutamate methylesterase 0.21 DZA65_RS15815 Zn-dependent oxidoreductase low > 75
Dickeya dianthicola 67-19 0.45 HGI48_RS13570 chemotaxis response regulator protein-glutamate methylesterase 0.21 HGI48_RS15070 Zn-dependent oxidoreductase low > 71
Enterobacter sp. TBS_079 0.45 MPMX20_02787 Protein-glutamate methylesterase/protein-glutamine glutaminase 0.88 MPMX20_00116 L-threonine 3-dehydrogenase low > 85
Erwinia amylovora T8 0.44 OLJFJH_12760 chemotaxis response regulator protein-glutamate methylesterase 0.16 OLJFJH_12295 butanediol dehydrogenase low > 58
Pectobacterium carotovorum WPP14 0.44 HER17_RS08120 chemotaxis response regulator protein-glutamate methylesterase 0.84 HER17_RS20760 L-threonine 3-dehydrogenase low > 75
Enterobacter asburiae PDN3 0.44 EX28DRAFT_0673 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain 0.88 EX28DRAFT_3869 L-threonine 3-dehydrogenase (EC 1.1.1.103) low > 76
Escherichia coli Nissle 1917 0.44 ECOLIN_RS10755 protein-glutamate methylesterase/protein glutamine deamidase 0.89 ECOLIN_RS20635 L-threonine 3-dehydrogenase low > 55
Escherichia coli ECRC99 0.44 KEDOAH_01955 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 KEDOAH_12435 tdh L-threonine 3-dehydrogenase — —
Escherichia coli ECOR38 0.44 HEPCGN_04570 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 HEPCGN_14555 tdh L-threonine 3-dehydrogenase low > 88
Escherichia coli BL21 0.44 ECD_01854 fused chemotaxis regulator: protein-glutamate methylesterase in two-component regulatory system with CheA 0.89 ECD_03474 L-threonine 3-dehydrogenase, NAD(P)-binding low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.44 OHPLBJKB_01845 Chemotaxis response regulator protein-glutamate methylesterase 0.89 OHPLBJKB_00083 L-threonine 3-dehydrogenase low > 74
Escherichia coli ECRC101 0.44 MCAODC_19255 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 MCAODC_06225 tdh L-threonine 3-dehydrogenase low > 87
Castellaniella sp019104865 MT123 0.44 ABCV34_RS05815 chemotaxis response regulator protein-glutamate methylesterase 0.78 ABCV34_RS14100 L-threonine 3-dehydrogenase low > 48
Escherichia coli ECRC100 0.44 OKFHMN_26150 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 OKFHMN_15715 tdh L-threonine 3-dehydrogenase low > 79
Escherichia coli ECRC102 0.44 NIAGMN_01910 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 NIAGMN_13475 tdh L-threonine 3-dehydrogenase low > 80
Escherichia coli ECRC98 0.44 JDDGAC_00725 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 JDDGAC_19340 tdh L-threonine 3-dehydrogenase 0.48 57
Escherichia coli ECRC62 0.44 BNILDI_15380 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 BNILDI_03920 tdh L-threonine 3-dehydrogenase low > 75
Escherichia coli ECOR27 0.44 NOLOHH_16590 cheB protein-glutamate methylesterase/protein glutamine deamidase 0.89 NOLOHH_07595 tdh L-threonine 3-dehydrogenase low > 76
Escherichia coli BW25113 0.44 b1883 cheB chemotaxis-specific methylesterase (NCBI) 0.89 b3616 tdh L-threonine 3-dehydrogenase (NCBI) low > 76
Escherichia fergusonii Becca 0.44 EFB2_02060 Protein-glutamate methylesterase/protein-glutamine glutaminase 0.89 EFB2_00194 L-threonine 3-dehydrogenase low > 86
Pantoea agglomerans CFBP13505 P0401 0.43 PagCFBP13505_RS02210 chemotaxis response regulator protein-glutamate methylesterase 0.84 PagCFBP13505_RS18645 L-threonine 3-dehydrogenase low > 74
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS35785 chemotaxis protein 0.79 RR42_RS22860 l-threonine 3-dehydrogenase low > 128
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_05747 two-component system, chemotaxis family, response regulator CheB 0.79 H281DRAFT_03586 L-threonine 3-dehydrogenase low > 103
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS28985 chemotaxis response regulator protein-glutamate methylesterase 0.79 QEN71_RS16540 L-threonine 3-dehydrogenase 0.85 125
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS18970 chemotaxis protein 0.80 BPHYT_RS34650 l-threonine 3-dehydrogenase low > 109
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF1664 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) 0.89 GFF394 L-threonine 3-dehydrogenase (EC 1.1.1.103) low > 78
Rhodanobacter denitrificans MT42 0.43 LRK55_RS13410 chemotaxis response regulator protein-glutamate methylesterase 0.68 LRK55_RS00420 L-threonine 3-dehydrogenase low > 63
Rhodanobacter denitrificans FW104-10B01 0.43 LRK54_RS13670 chemotaxis response regulator protein-glutamate methylesterase 0.68 LRK54_RS00650 L-threonine 3-dehydrogenase low > 59
Rhodanobacter sp000427505 FW510-R12 0.43 LRK53_RS14905 chemotaxis response regulator protein-glutamate methylesterase 0.68 LRK53_RS09500 L-threonine 3-dehydrogenase low > 59
Pantoea sp. MT58 0.43 IAI47_08330 chemotaxis response regulator protein-glutamate methylesterase 0.85 IAI47_00700 L-threonine 3-dehydrogenase low > 76
Caulobacter crescentus NA1000 0.43 CCNA_00445 receiver domain-glutamate methylesterase cheBI 0.15 CCNA_02929 sorbitol dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_00445 receiver domain-glutamate methylesterase cheBI 0.15 CCNA_02929 sorbitol dehydrogenase low > 67
Paraburkholderia graminis OAS925 0.43 ABIE53_000119 two-component system chemotaxis response regulator CheB 0.78 ABIE53_004673 threonine 3-dehydrogenase low > 113
Azospirillum brasilense Sp245 0.42 AZOBR_RS14260 chemotaxis protein 0.17 AZOBR_RS13230 alcohol dehydrogenase low > 97
Herbaspirillum seropedicae SmR1 0.42 HSERO_RS10125 chemotaxis protein 0.18 HSERO_RS05485 phosphoesterase low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF1479 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) 0.22 GFF1899 L-threonine 3-dehydrogenase (EC 1.1.1.103) low > 90
Shewanella oneidensis MR-1 0.41 SO2126 cheB-1 protein-glutamate methylesterase CheB (NCBI ptt file) 0.88 SO4673 tdh threonine 3-dehydrogenase (NCBI ptt file) low > 76
Rhodanobacter sp. FW510-T8 0.41 OKGIIK_02915 cheB Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains 0.68 OKGIIK_06605 tdh L-threonine 3-dehydrogenase low > 53
Sinorhizobium meliloti 1021 0.41 SMc03010 chemotaxis-specific methylesterase 0.69 SMc01564 L-threonine 3-dehydrogenase low > 103
Ralstonia solanacearum GMI1000 0.41 RS_RS23895 chemotaxis response regulator protein-glutamate methylesterase 0.19 RS_RS21660 L-idonate 5-dehydrogenase low > 80
Shewanella sp. ANA-3 0.41 Shewana3_2213 response regulator receiver modulated CheB methylesterase (RefSeq) 0.88 Shewana3_4105 tdh L-threonine 3-dehydrogenase (RefSeq) low > 73
Acidovorax sp. GW101-3H11 0.40 Ac3H11_1425 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) 0.15 Ac3H11_3163 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 79
Rhizobium sp. OAE497 0.40 ABIE40_RS02890 protein-glutamate O-methylesterase CheB 0.70 ABIE40_RS12725 L-threonine 3-dehydrogenase low > 107
Ralstonia sp. UNC404CL21Col 0.40 ABZR87_RS17990 chemotaxis response regulator protein-glutamate methylesterase 0.17 ABZR87_RS12015 zinc-binding alcohol dehydrogenase family protein low > 80
Agrobacterium fabrum C58 0.40 Atu0519 protein-glutamate methylesterase 0.21 Atu1408 sorbitol dehydrogenase low > 89
Ralstonia solanacearum PSI07 0.40 RPSI07_RS06230 chemotaxis response regulator protein-glutamate methylesterase 0.19 RPSI07_RS02790 L-idonate 5-dehydrogenase low > 81
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS17415 chemotaxis response regulator protein-glutamate methylesterase 0.15 RALBFv3_RS07825 alcohol dehydrogenase AdhP low > 76
Ralstonia solanacearum UW163 0.40 UW163_RS21735 chemotaxis response regulator protein-glutamate methylesterase 0.15 UW163_RS05800 alcohol dehydrogenase AdhP — —
Azospirillum sp. SherDot2 0.40 MPMX19_01953 Protein-glutamate methylesterase/protein-glutamine glutaminase 0.22 MPMX19_06785 L-idonate 5-dehydrogenase (NAD(P)(+)) low > 112
Pseudomonas aeruginosa PA14 0.40 IKLFDK_24680 Protein-glutamate methylesterase/protein-glutamine glutaminase 2 0.19 IKLFDK_21130 butanediol dehydrogenase 0.19 46
Rhodospirillum rubrum S1H 0.40 Rru_A1406 Two component CheB methylesterase (NCBI) 0.18 Rru_A0252 Zinc-containing alcohol dehydrogenase superfamily (NCBI) low > 58
Pseudomonas aeruginosa MRSN321 0.39 DY961_RS27150 chemotaxis response regulator protein-glutamate methylesterase 0.19 DY961_RS27955 2 3-butanediol dehydrogenase low > 100
Pseudomonas aeruginosa PUPa3 0.39 DQ20_RS31680 chemotaxis response regulator protein-glutamate methylesterase 0.19 DQ20_RS47680 2 3-butanediol dehydrogenase low > 101
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_1084 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain 0.56 Ga0059261_2605 Threonine dehydrogenase and related Zn-dependent dehydrogenases low > 68
Rhodopseudomonas palustris CGA009 0.38 TX73_000705 chemotaxis response regulator protein-glutamate methylesterase 0.15 TX73_010080 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 86
Pseudomonas fluorescens SBW25-INTG 0.38 PFLU_RS24965 chemotaxis response regulator protein-glutamate methylesterase 0.19 PFLU_RS19505 erythritol/L-threitol dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.38 PFLU_RS24965 chemotaxis response regulator protein-glutamate methylesterase 0.19 PFLU_RS19505 erythritol/L-threitol dehydrogenase low > 109
Pseudomonas fluorescens FW300-N2E2 0.38 Pf6N2E2_1775 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) 0.15 Pf6N2E2_668 2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4) low > 103
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0781 Protein-glutamate methylesterase 0.17 Psyr_2567 Zinc-containing alcohol dehydrogenase superfamily low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0781 Protein-glutamate methylesterase 0.17 Psyr_2567 Zinc-containing alcohol dehydrogenase superfamily low > 86
Brevundimonas sp. GW460-12-10-14-LB2 0.37 A4249_RS15580 chemotaxis response regulator protein-glutamate methylesterase 0.55 A4249_RS02510 L-threonine 3-dehydrogenase low > 48
Bosea sp. OAE506 0.37 ABIE41_RS01665 chemotaxis response regulator protein-glutamate methylesterase 0.21 ABIE41_RS09605 L-idonate 5-dehydrogenase low > 77
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_29840 chemotaxis protein CheY 0.24 AO356_28545 alcohol dehydrogenase — —
Pseudomonas stutzeri RCH2 0.37 Psest_0653 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain 0.17 Psest_1428 Threonine dehydrogenase and related Zn-dependent dehydrogenases — —
Pseudomonas sp. RS175 0.37 PFR28_01434 Protein-glutamate methylesterase/protein-glutamine glutaminase 0.16 PFR28_01772 putative zinc-type alcohol dehydrogenase-like protein YdjJ low > 88
Pseudomonas lactucae CFBP13502 0.36 GEMAOFIL_03221 Protein-glutamate methylesterase/protein-glutamine glutaminase 0.17 GEMAOFIL_03833 L-idonate 5-dehydrogenase (NAD(P)(+)) — —
Pseudomonas sp. S08-1 0.35 OH686_21840 Chemotaxis response regulator protein-glutamate methylesterase CheB 0.15 OH686_18150 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Sphingobium sp. HT1-2 0.22 GFF331 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) 0.17 GFF4455 Alcohol dehydrogenase (EC 1.1.1.1) low > 95
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_07600 chemotaxis response regulator protein-glutamate methylesterase 0.16 CA264_20025 glutathione-dependent formaldehyde dehydrogenase low > 74
Phaeobacter inhibens DSM 17395 0.18 PGA1_262p02160 putative chemotaxis response regulator protein-glutamate methylesterase 0.58 PGA1_c34320 L-threonine 3-dehydrogenase (EC 1.1.1.103) (from data) low > 62

Not shown: 6 genomes with orthologs for CSW01_19520 only; 33 genomes with orthologs for CSW01_18565 only