Conservation of cofitness between CSW01_02425 and CSW01_02845 in Vibrio cholerae E7946 ATCC 55056

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02425 YggW family oxidoreductase 1.0 CSW01_02845 cysteine synthase CysM 0.54 11
Pectobacterium carotovorum WPP14 0.69 HER17_RS03785 radical SAM family heme chaperone HemW 0.68 HER17_RS17210 cysteine synthase CysM low > 75
Dickeya dadantii 3937 0.68 DDA3937_RS17325 radical SAM family heme chaperone HemW 0.66 DDA3937_RS04425 cysteine synthase CysM 0.68 50
Dickeya dianthicola 67-19 0.68 HGI48_RS17370 radical SAM family heme chaperone HemW 0.65 HGI48_RS04400 cysteine synthase CysM 0.40 34
Dickeya dianthicola ME23 0.68 DZA65_RS18460 radical SAM family heme chaperone HemW 0.66 DZA65_RS04315 cysteine synthase CysM low > 75
Serratia liquefaciens MT49 0.68 IAI46_21435 radical SAM family heme chaperone HemW 0.69 IAI46_18490 cysteine synthase CysM low > 86
Escherichia coli ECRC99 0.67 KEDOAH_08905 hemW radical SAM family heme chaperone HemW 0.71 KEDOAH_06050 cysM cysteine synthase B
Escherichia coli ECRC102 0.67 NIAGMN_17000 hemW radical SAM family heme chaperone HemW 0.71 NIAGMN_19940 cysM cysteine synthase B low > 80
Escherichia coli ECRC98 0.67 JDDGAC_22865 hemW radical SAM family heme chaperone HemW 0.71 JDDGAC_26120 cysM cysteine synthase B low > 87
Escherichia coli ECRC101 0.67 MCAODC_09755 hemW radical SAM family heme chaperone HemW 0.71 MCAODC_12700 cysM cysteine synthase B low > 88
Escherichia coli ECRC100 0.67 OKFHMN_19235 hemW radical SAM family heme chaperone HemW 0.71 OKFHMN_22170 cysM cysteine synthase B low > 79
Escherichia fergusonii Becca 0.66 EFB2_00947 Heme chaperone HemW 0.71 EFB2_01456 Cysteine synthase B low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.66 OHPLBJKB_00761 Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR 0.71 OHPLBJKB_01302 Cysteine synthase B low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.66 GFF3058 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.71 GFF2055 Cysteine synthase (EC 2.5.1.47) low > 78
Escherichia coli BW25113 0.66 b2955 yggW coproporphyrinogen III oxidase (NCBI) 0.71 b2421 cysM cysteine synthase B (O-acetylserine sulfhydrolase B) (NCBI) low > 76
Escherichia coli BL21 0.66 ECD_02785 HemN family putative oxidoreductase 0.71 ECD_02321 cysteine synthase B (O-acetylserine sulfhydrolase B) low > 61
Erwinia tracheiphila HP pepo 2.2 0.66 IJEDHG_03465 hemW radical SAM family heme chaperone HemW 0.64 IJEDHG_16800 cysM cysteine synthase CysM
Escherichia coli ECRC62 0.66 BNILDI_09685 hemW radical SAM family heme chaperone HemW 0.71 BNILDI_12715 cysM cysteine synthase B low > 75
Erwinia tracheiphila SCR3 0.66 LU632_RS05445 hemW radical SAM family heme chaperone HemW 0.64 LU632_RS06675 cysM cysteine synthase CysM low > 74
Escherichia coli Nissle 1917 0.65 ECOLIN_RS16435 radical SAM family heme chaperone HemW 0.71 ECOLIN_RS13900 cysteine synthase B
Escherichia coli ECOR38 0.65 HEPCGN_18540 hemW radical SAM family heme chaperone HemW 0.71 HEPCGN_21345 cysM cysteine synthase B low > 88
Escherichia coli ECOR27 0.65 NOLOHH_11105 hemW radical SAM family heme chaperone HemW 0.71 NOLOHH_13850 cysM cysteine synthase B low > 76
Enterobacter sp. TBS_079 0.65 MPMX20_03813 Heme chaperone HemW 0.71 MPMX20_03313 Cysteine synthase B
Enterobacter asburiae PDN3 0.65 EX28DRAFT_2993 putative oxygen-independent coproporphyrinogen III oxidase 0.72 EX28DRAFT_0209 cysteine synthase B
Pantoea agglomerans CFBP13505 P0401 0.65 PagCFBP13505_RS16115 radical SAM family heme chaperone HemW 0.66 PagCFBP13505_RS19950 cysteine synthase CysM low > 74
Pantoea sp. MT58 0.65 IAI47_03580 radical SAM family heme chaperone HemW 0.66 IAI47_05405 cysteine synthase CysM low > 76
Klebsiella michiganensis M5al 0.65 BWI76_RS24120 YggW family oxidoreductase 0.71 BWI76_RS20685 cysteine synthase B
Klebsiella pneumoniae MKP103 0.64 KDGMDA_04635 radical SAM family heme chaperone HemW 0.72 KDGMDA_27525 cysteine synthase B low > 95
Erwinia amylovora T8 0.64 OLJFJH_08515 radical SAM family heme chaperone HemW 0.65 OLJFJH_10835 cysteine synthase CysM low > 58
Rahnella sp. WP5 0.63 EX31_RS02710 radical SAM family heme chaperone HemW 0.72 EX31_RS20205 cysteine synthase CysM low > 89
Shewanella sp. ANA-3 0.59 Shewana3_1188 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.82 Shewana3_3188 cysM cysteine synthase B (RefSeq) low > 73
Shewanella oneidensis MR-1 0.59 SO3359 oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) 0.79 SO3598 cysM cysteine synthase B (NCBI ptt file) low > 76
Pseudomonas sp. RS175 0.54 PFR28_04249 Heme chaperone HemW 0.74 PFR28_03225 Cysteine synthase B
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_4593 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.74 Pf6N2E2_5721 Cysteine synthase B (EC 2.5.1.47)
Kangiella aquimarina DSM 16071 0.54 B158DRAFT_0201 coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) 0.33 B158DRAFT_1208 cystathionine beta-synthase (acetylserine-dependent) (EC 4.2.1.-) low > 40
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_08200 coproporphyrinogen III oxidase 0.74 AO353_02720 cysteine synthase low > 101
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_1003 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.74 PfGW456L13_2032 Cysteine synthase B (EC 2.5.1.47) low > 87
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS28405 radical SAM family heme chaperone HemW 0.73 PFLU_RS22105 cysteine synthase CysM low > 109
Pseudomonas simiae WCS417 0.53 PS417_26760 oxidase 0.72 PS417_20160 cysteine synthase low > 88
Pseudomonas fluorescens SBW25 0.53 PFLU_RS28405 radical SAM family heme chaperone HemW 0.73 PFLU_RS22105 cysteine synthase CysM low > 109
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_2334 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.73 Pf1N1B4_3506 Cysteine synthase B (EC 2.5.1.47) 0.29 77
Pseudomonas sp. DMC3 0.53 GFF216 Heme chaperone HemW 0.73 GFF4820 Cysteine synthase B low > 89
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_13390 coproporphyrinogen III oxidase 0.73 AO356_19050 cysteine synthase low > 104
Pseudomonas sp. SVBP6 0.52 COO64_RS12965 hemW radical SAM family heme chaperone HemW 0.75 COO64_RS07335 cysM cysteine synthase CysM low > 93
Pseudomonas aeruginosa PA14 0.51 IKLFDK_23495 radical SAM family heme chaperone HemW 0.75 IKLFDK_04190 cysteine synthase B low > 100
Pseudomonas segetis P6 0.51 MPMX49_00603 Heme chaperone HemW 0.75 MPMX49_01652 Cysteine synthase B
Pseudomonas sp. BP01 0.51 JOY50_RS20875 hemW radical SAM family heme chaperone HemW 0.75 JOY50_RS23900 cysM cysteine synthase CysM 0.32 73
Pseudomonas sp. S08-1 0.51 OH686_11020 Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW 0.74 OH686_18950 cysteine synthase B
Pseudomonas putida KT2440 0.51 PP_5101 coproporphyrinogen/heterocyclic compound oxidase (aerobic) 0.74 PP_1654 cysteine synthase B low > 96
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_0471 coproporphyrinogen III oxidase, anaerobic 0.72 Psyr_3697 cysteine synthase
Pseudomonas stutzeri RCH2 0.50 Psest_0276 putative oxygen-independent coproporphyrinogen III oxidase 0.76 Psest_1638 cysteine synthase B
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_0471 coproporphyrinogen III oxidase, anaerobic 0.72 Psyr_3697 cysteine synthase
Pseudomonas lactucae CFBP13502 0.49 GEMAOFIL_05489 Heme chaperone HemW 0.73 GEMAOFIL_04225 Cysteine synthase B
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.1224.1 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.34 Xcc-8004.1247.1 Cysteine synthase (EC 2.5.1.47) low > 74
Dyella japonica UNC79MFTsu3.2 0.47 ABZR86_RS11910 radical SAM family heme chaperone HemW 0.33 ABZR86_RS05875 cysteine synthase A low > 74
Lysobacter sp. OAE881 0.47 ABIE51_RS17300 radical SAM family heme chaperone HemW 0.35 ABIE51_RS15860 cysteine synthase A low > 62
Rhodanobacter denitrificans MT42 0.46 LRK55_RS11460 radical SAM family heme chaperone HemW 0.35 LRK55_RS00680 cysteine synthase A low > 63
Rhodanobacter denitrificans FW104-10B01 0.46 LRK54_RS11735 radical SAM family heme chaperone HemW 0.35 LRK54_RS00905 cysteine synthase A low > 59
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_04010 oxygen-independent coproporphyrinogen-3 oxidase 0.65 H281DRAFT_03911 cysteine synthase
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS04880 coproporphyrinogen III oxidase 0.64 RR42_RS04535 cysteine synthase low > 128
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS15335 coproporphyrinogen III oxidase 0.63 BPHYT_RS14845 cysteine synthase low > 109
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS10665 coproporphyrinogen III oxidase 0.64 HSERO_RS04915 cysteine synthase
Dechlorosoma suillum PS 0.44 Dsui_0491 putative oxygen-independent coproporphyrinogen III oxidase 0.66 Dsui_1954 cysteine synthase B
Paraburkholderia graminis OAS925 0.44 ABIE53_003236 putative oxygen-independent coproporphyrinogen III oxidase 0.63 ABIE53_003144 cysteine synthase B low > 113
Variovorax sp. OAS795 0.44 ABID97_RS23630 radical SAM family heme chaperone HemW 0.66 ABID97_RS07880 cysteine synthase CysM
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS03635 radical SAM family heme chaperone HemW 0.65 QEN71_RS04135 cysteine synthase CysM
Variovorax sp. SCN45 0.44 GFF2383 Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW 0.67 GFF6025 Cysteine synthase B (EC 2.5.1.47)
Ralstonia solanacearum PSI07 0.44 RPSI07_RS13830 oxygen-independent coproporphyrinogen III oxidase-like protein 0.66 RPSI07_RS19645 cysteine synthase CysM
Marinobacter adhaerens HP15 0.43 HP15_280 putative oxygen-independent coproporphyrinogen III oxidase 0.76 HP15_789 cysteine synthase B
Methylophilus sp. DMC18 0.43 GFF2148 Heme chaperone HemW 0.68 GFF907 Cysteine synthase B
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS15265 radical SAM family heme chaperone HemW 0.65 ABZR87_RS09515 cysteine synthase CysM low > 80
Ralstonia solanacearum GMI1000 0.42 RS_RS10840 oxygen-independent coproporphyrinogen III oxidase-like protein 0.66 RS_RS04560 cysteine synthase CysM
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS03355 oxygen-independent coproporphyrinogen III oxidase-like protein 0.66 RALBFv3_RS13825 cysteine synthase CysM
Ralstonia solanacearum UW163 0.42 UW163_RS10365 oxygen-independent coproporphyrinogen III oxidase-like protein 0.66 UW163_RS15985 cysteine synthase CysM
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF3256 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.66 GFF709 Cysteine synthase B (EC 2.5.1.47) 0.52 58
Acinetobacter baumannii LAC-4 0.41 RR41_RS17015 radical SAM family heme chaperone HemW 0.72 RR41_RS16095 cysteine synthase CysM
Acidovorax sp. GW101-3H11 0.41 Ac3H11_3672 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.66 Ac3H11_644 Cysteine synthase B (EC 2.5.1.47)
Acinetobacter radioresistens SK82 0.41 MPMX26_00308 Heme chaperone HemW 0.74 MPMX26_00536 Cysteine synthase B
Castellaniella sp019104865 MT123 0.41 ABCV34_RS03525 radical SAM family heme chaperone HemW 0.62 ABCV34_RS07055 cysteine synthase CysM
Phaeobacter inhibens DSM 17395 0.28 PGA1_c35050 oxygen-independent coproporphyrinogen III oxidase HemN 0.27 PGA1_c13950 cysteine synthase CysK
Dinoroseobacter shibae DFL-12 0.28 Dshi_3460 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.28 Dshi_2314 Pyridoxal-5'-phosphate-dependent protein beta subunit (RefSeq)
Caulobacter crescentus NA1000 0.26 CCNA_00144 oxygen-independent coproporphyrinogen-III oxidase 0.31 CCNA_01493 cysteine synthase low > 66
Caulobacter crescentus NA1000 Δfur 0.26 CCNA_00144 oxygen-independent coproporphyrinogen-III oxidase 0.31 CCNA_01493 cysteine synthase low > 67
Fusobacterium nucleatum SB010 0.25 HUW76_07285 radical SAM family heme chaperone HemW 0.30 HUW76_04155 cysteine synthase A
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_0628 putative oxygen-independent coproporphyrinogen III oxidase 0.55 Echvi_0220 cysteine synthase B
Pontibacter actiniarum KMM 6156, DSM 19842 0.22 CA264_16765 coproporphyrinogen III oxidase 0.57 CA264_08940 cysteine synthase B low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.21 ABZR88_RS03545 radical SAM family heme chaperone HemW 0.54 ABZR88_RS13695 cysteine synthase CysM
Cellulophaga baltica 18 0.20 M666_RS07265 radical SAM family heme chaperone HemW 0.55 M666_RS17050 cysteine synthase CysM

Not shown: 22 genomes with orthologs for CSW01_02425 only; 1 genomes with orthologs for CSW01_02845 only