Conservation of cofitness between CSW01_00850 and CSW01_01015 in Vibrio cholerae E7946 ATCC 55056

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00850 multidrug resistance protein 1.0 CSW01_01015 DNA helicase II 0.73 7
Shewanella sp. ANA-3 0.72 Shewana3_0371 acriflavin resistance protein (RefSeq) 0.67 Shewana3_0469 uvrD DNA-dependent helicase II (RefSeq) low > 73
Shewanella amazonensis SB2B 0.71 Sama_3269 putative multidrug resistance protein (RefSeq) 0.66 Sama_0419 uvrD DNA-dependent helicase II (RefSeq) low > 62
Rhodospirillum rubrum S1H 0.49 Rru_A3699 Acriflavin resistance protein (NCBI) 0.32 Rru_A1536 UvrD/REP helicase (NCBI) low > 58
Azospirillum brasilense Sp245 0.49 AZOBR_RS31320 acriflavine resistance protein B 0.35 AZOBR_RS12445 DNA helicase II low > 97
Magnetospirillum magneticum AMB-1 0.48 AMB_RS17260 acriflavine resistance protein B 0.34 AMB_RS03725 DNA helicase II low > 64
Pseudomonas segetis P6 0.48 MPMX49_03771 Multidrug efflux pump subunit AcrB 0.58 MPMX49_00180 DNA helicase II low > 75
Azospirillum sp. SherDot2 0.48 MPMX19_05610 Efflux pump membrane transporter BepE 0.34 MPMX19_01610 ATP-dependent DNA helicase PcrA low > 112
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS24405 multidrug efflux RND transporter permease subunit 0.59 PFLU_RS29900 DNA helicase II low > 109
Pseudomonas fluorescens SBW25 0.47 PFLU_RS24405 multidrug efflux RND transporter permease subunit 0.59 PFLU_RS29900 DNA helicase II low > 109
Pseudomonas sp. RS175 0.47 PFR28_03330 Multidrug efflux pump subunit AcrB 0.59 PFR28_04523 DNA helicase II low > 88
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_18440 acriflavine resistance protein B 0.59 AO356_11990 DNA helicase II 0.35 41
Pseudomonas sp. S08-1 0.47 OH686_17360 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) 0.59 OH686_13045 ATP-dependent DNA helicase UvrD/PcrA low > 80
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_5614 RND multidrug efflux transporter; Acriflavin resistance protein 0.59 Pf6N2E2_4273 ATP-dependent DNA helicase UvrD/PcrA low > 103
Pseudomonas sp. BP01 0.47 JOY50_RS14955 multidrug efflux RND transporter permease subunit 0.60 JOY50_RS08735 uvrD DNA helicase II low > 84
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_720 RND multidrug efflux transporter; Acriflavin resistance protein 0.59 Pf1N1B4_2005 ATP-dependent DNA helicase UvrD/PcrA low > 87
Pseudomonas putida KT2440 0.46 PP_0906 putative Multidrug efflux RND transporter 0.60 PP_5352 DNA-dependent ATPase I and helicase II, nucleotide Excision Repair Complex low > 96
Pseudomonas sp. SVBP6 0.46 COO64_RS12055 multidrug efflux RND transporter permease subunit 0.60 COO64_RS01845 uvrD DNA helicase II low > 93
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_04000 acriflavine resistance protein B 0.59 AO353_10055 DNA helicase II low > 101
Pseudomonas aeruginosa PUPa3 0.46 DQ20_RS57065 mexW;inference=COORDINATES multidrug efflux RND transporter permease subunit MexW 0.60 DQ20_RS57955 uvrD;go_function=DNA DNA helicase II low > 101
Pseudomonas aeruginosa PA14 0.46 IKLFDK_02225 multidrug efflux RND transporter permease subunit MexW 0.60 IKLFDK_26200 DNA helicase II low > 98
Pseudomonas aeruginosa MRSN321 0.46 DY961_RS24615 mexW;inference=COORDINATES multidrug efflux RND transporter permease subunit MexW 0.60 DY961_RS25505 uvrD;go_function=DNA DNA helicase II low > 100
Pseudomonas sp. DMC3 0.46 GFF5069 Multidrug efflux pump subunit AcrB 0.59 GFF512 DNA helicase II 0.53 58
Marinobacter adhaerens HP15 0.46 HP15_3262 multidrug resistance protein 0.56 HP15_3403 UvrD/REP helicase low > 73
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_1771 RND multidrug efflux transporter; Acriflavin resistance protein 0.59 PfGW456L13_724 ATP-dependent DNA helicase UvrD/PcrA low > 87
Pseudomonas stutzeri RCH2 0.45 Psest_1153 Cation/multidrug efflux pump 0.59 Psest_4098 Superfamily I DNA and RNA helicases low > 67
Variovorax sp. SCN45 0.45 GFF3509 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) => MexI of MexHI-OpmD system 0.43 GFF4000 ATP-dependent DNA helicase UvrD/PcrA (EC 3.6.4.12) low > 127
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS26025 efflux RND transporter permease subunit 0.44 QEN71_RS05110 3'-5' exonuclease — —
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS29560 acriflavine resistance protein B 0.45 BPHYT_RS13840 DNA-dependent helicase — —
Dechlorosoma suillum PS 0.35 Dsui_1555 cation/multidrug efflux pump 0.45 Dsui_1227 DNA/RNA helicase, superfamily I low > 51
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF4261 RND multidrug efflux transporter; Acriflavin resistance protein 0.42 GFF5598 ATP-dependent DNA helicase UvrD/PcrA — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_482 RND multidrug efflux transporter; Acriflavin resistance protein 0.44 Ac3H11_1660 ATP-dependent DNA helicase UvrD/PcrA low > 79
Desulfovibrio vulgaris Hildenborough JW710 0.25 DVU0061 multidrug resistance protein, putative (TIGR) 0.19 DVU0156 pcrA ATP-dependent DNA helicase, UvrD/REP family (TIGR) low > 55
Synechococcus elongatus PCC 7942 0.24 Synpcc7942_2369 acrF Hydrophobe/amphiphile efflux-1 HAE1 0.29 Synpcc7942_2168 pcrA ATP-dependent DNA helicase, Rep family low > 38
Methylophilus sp. DMC18 0.24 GFF1649 Efflux pump membrane transporter BepE 0.48 GFF1664 DNA helicase II low > 43
Enterobacter asburiae PDN3 0.24 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family 0.70 EX28DRAFT_4482 ATP-dependent DNA helicase UvrD (EC 3.6.1.-) low > 76
Klebsiella michiganensis M5al 0.24 BWI76_RS06775 multidrug efflux RND transporter permease subunit 0.71 BWI76_RS01220 DNA-dependent helicase II low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF4246 RND efflux system, inner membrane transporter CmeB 0.71 GFF241 ATP-dependent DNA helicase UvrD/PcrA low > 78
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_01261 Multidrug efflux pump subunit AcrB 0.71 OHPLBJKB_04237 DNA helicase II low > 74
Escherichia fergusonii Becca 0.24 EFB2_01418 Multidrug efflux pump subunit AcrB 0.71 EFB2_04824 DNA helicase II low > 86
Escherichia coli BW25113 0.24 b2470 acrD aminoglycoside/multidrug efflux system (NCBI) 0.71 b3813 uvrD DNA-dependent ATPase I and helicase II (NCBI) low > 76
Escherichia coli BL21 0.24 ECD_02361 aminoglycoside/multidrug efflux system 0.71 ECD_03689 DNA-dependent ATPase I and helicase II — —
Escherichia coli ECOR38 0.24 HEPCGN_21140 acrD multidrug efflux RND transporter permease AcrD 0.71 HEPCGN_13115 uvrD DNA helicase II low > 88
Escherichia coli ECRC62 0.24 BNILDI_12460 acrD multidrug efflux RND transporter permease AcrD 0.71 BNILDI_04995 uvrD DNA helicase II low > 75
Escherichia coli Nissle 1917 0.24 ECOLIN_RS14090 multidrug efflux RND transporter permease AcrD 0.71 ECOLIN_RS21885 DNA helicase II low > 55
Escherichia coli ECRC100 0.24 OKFHMN_21970 acrD multidrug efflux RND transporter permease AcrD 0.71 OKFHMN_14410 uvrD DNA helicase II low > 79
Escherichia coli ECRC98 0.24 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD 0.71 JDDGAC_18035 uvrD DNA helicase II low > 87
Escherichia coli ECOR27 0.24 NOLOHH_13650 acrD multidrug efflux RND transporter permease AcrD 0.71 NOLOHH_06540 uvrD DNA helicase II low > 76
Enterobacter sp. TBS_079 0.24 MPMX20_01064 Multidrug efflux pump subunit AcrB 0.70 MPMX20_04463 DNA helicase II low > 85
Escherichia coli ECRC99 0.24 KEDOAH_06250 acrD multidrug efflux RND transporter permease AcrD 0.71 KEDOAH_13740 uvrD DNA helicase II — —
Escherichia coli ECRC101 0.24 MCAODC_12500 acrD multidrug efflux RND transporter permease AcrD 0.71 MCAODC_04915 uvrD DNA helicase II low > 87
Escherichia coli ECRC102 0.24 NIAGMN_19740 acrD multidrug efflux RND transporter permease AcrD 0.71 NIAGMN_12165 uvrD DNA helicase II low > 80
Klebsiella pneumoniae MKP103 0.24 KDGMDA_14835 acriflavine resistance protein B 0.71 KDGMDA_09710 DNA helicase II low > 95
Paraburkholderia graminis OAS925 0.24 ABIE53_005788 multidrug efflux pump 0.45 ABIE53_002936 DNA helicase-2/ATP-dependent DNA helicase PcrA — —
Pseudomonas orientalis W4I3 0.24 QF045_RS16760 efflux RND transporter permease subunit 0.59 QF045_RS02600 DNA helicase II low > 93
Desulfovibrio vulgaris Miyazaki F 0.24 DvMF_2163 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family (RefSeq) 0.17 DvMF_1967 UvrD/REP helicase (RefSeq) low > 51
Pseudomonas syringae pv. syringae B728a 0.23 Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 0.58 Psyr_5065 ATP-dependent DNA helicase UvrD 0.36 59
Pseudomonas syringae pv. syringae B728a ΔmexB 0.23 Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 0.58 Psyr_5065 ATP-dependent DNA helicase UvrD low > 86
Bosea sp. OAE506 0.23 ABIE41_RS01595 efflux RND transporter permease subunit 0.35 ABIE41_RS12730 UvrD-helicase domain-containing protein low > 77
Rhodanobacter sp. FW510-T8 0.23 OKGIIK_11990 acrB acriflavine resistance protein B 0.55 OKGIIK_16775 DNA helicase low > 53
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS11745 efflux RND transporter permease subunit 0.55 ABZR86_RS16965 DNA helicase II low > 74
Pseudomonas lactucae CFBP13502 0.23 GEMAOFIL_03223 multidrug efflux RND transporter permease subunit OqxB9 0.59 GEMAOFIL_00116 DNA helicase II low > 96
Rahnella sp. WP5 0.23 EX31_RS22470 multidrug efflux RND transporter permease subunit 0.68 EX31_RS15175 DNA helicase II low > 89
Serratia liquefaciens MT49 0.23 IAI46_18690 multidrug efflux RND transporter permease AcrD 0.71 IAI46_00735 DNA helicase II low > 87
Rhodanobacter denitrificans MT42 0.23 LRK55_RS11630 efflux RND transporter permease subunit 0.54 LRK55_RS06595 DNA helicase II — —
Herbaspirillum seropedicae SmR1 0.23 HSERO_RS23055 multidrug transporter 0.43 HSERO_RS02160 DNA-dependent helicase low > 78
Cellulophaga baltica 18 0.23 M666_RS00650 efflux RND transporter permease subunit 0.30 M666_RS15390 3'-5' exonuclease — —
Rhodanobacter denitrificans FW104-10B01 0.23 LRK54_RS11905 efflux RND transporter permease subunit 0.54 LRK54_RS06850 DNA helicase II low > 59
Pantoea agglomerans CFBP13505 P0401 0.23 PagCFBP13505_RS19855 multidrug efflux RND transporter permease AcrD 0.68 PagCFBP13505_RS15370 DNA helicase II low > 74
Paraburkholderia bryophila 376MFSha3.1 0.23 H281DRAFT_04170 multidrug efflux pump 0.44 H281DRAFT_04469 ATP-dependent DNA helicase UvrD — —
Pectobacterium carotovorum WPP14 0.23 HER17_RS01560 multidrug efflux RND transporter permease AcrD 0.70 HER17_RS01360 DNA helicase II low > 75
Kangiella aquimarina DSM 16071 0.23 B158DRAFT_0733 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family 0.58 B158DRAFT_0238 Superfamily I DNA and RNA helicases low > 40
Dickeya dadantii 3937 0.23 DDA3937_RS05735 multidrug efflux RND transporter permease subunit 0.70 DDA3937_RS19880 DNA helicase II low > 74
Pantoea sp. MT58 0.23 IAI47_05310 multidrug efflux RND transporter permease AcrD 0.69 IAI47_18390 DNA helicase II low > 76
Erwinia amylovora T8 0.22 OLJFJH_17855 multidrug efflux RND transporter permease subunit AcrB 0.68 OLJFJH_06425 DNA helicase II low > 58
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS09795 efflux RND transporter permease subunit 0.43 ABZR87_RS15705 UvrD-helicase domain-containing protein low > 80
Variovorax sp. OAS795 0.22 ABID97_RS17350 efflux RND transporter permease subunit 0.44 ABID97_RS09150 UvrD-helicase domain-containing protein low > 91
Dickeya dianthicola ME23 0.22 DZA65_RS06115 multidrug efflux RND transporter permease subunit 0.70 DZA65_RS21080 DNA helicase II low > 75
Dickeya dianthicola 67-19 0.22 HGI48_RS05790 multidrug efflux RND transporter permease subunit 0.70 HGI48_RS20035 DNA helicase II low > 71
Ralstonia solanacearum GMI1000 0.22 RS_RS00045 multidrug efflux RND transporter permease subunit 0.42 RS_RS11220 DNA-dependent helicase low > 80
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS32420 multidrug efflux RND transporter permease subunit 0.44 RR42_RS15090 DNA helicase low > 128
Ralstonia solanacearum UW163 0.22 UW163_RS04135 multidrug efflux RND transporter permease subunit 0.42 UW163_RS09895 DNA-dependent helicase — —
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS09445 multidrug efflux RND transporter permease subunit 0.42 RALBFv3_RS03775 DNA-dependent helicase — —
Rhodanobacter sp000427505 FW510-R12 0.22 LRK53_RS07935 multidrug efflux RND transporter permease subunit 0.53 LRK53_RS01560 UvrD-helicase domain-containing protein — —
Ralstonia solanacearum PSI07 0.22 RPSI07_RS23905 hydrophobe/amphiphile efflux-1 family RND transporter 0.42 RPSI07_RS13455 DNA-dependent helicase — —
Erwinia tracheiphila SCR3 0.22 LU632_RS18185 efflux RND transporter permease subunit 0.68 LU632_RS24125 uvrD DNA helicase II — —
Erwinia tracheiphila HP pepo 2.2 0.21 IJEDHG_16580 adeB hydrophobe/amphiphile efflux-1 family RND transporter 0.68 IJEDHG_08770 uvrD DNA helicase II — —
Castellaniella sp019104865 MT123 0.20 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.42 ABCV34_RS05210 UvrD-helicase domain-containing protein low > 48

Not shown: 7 genomes with orthologs for CSW01_00850 only; 25 genomes with orthologs for CSW01_01015 only