| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Burkholderia phytofirmans PsJN | 1.0 | BPHYT_RS33915 | | isopropylmalate isomerase | 1.0 | BPHYT_RS33835 | | O-succinylhomoserine sulfhydrylase | 0.94 | 3 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.97 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | 0.94 | H281DRAFT_06059 | | O-succinylhomoserine sulfhydrylase | 0.71 | 6 |
| Paraburkholderia graminis OAS925 | 0.96 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | 0.93 | ABIE53_004817 | | O-succinylhomoserine sulfhydrylase | 0.95 | 3 |
| Paraburkholderia sabiae LMG 24235 | 0.95 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | 0.88 | QEN71_RS17685 | | O-succinylhomoserine sulfhydrylase | low | > 153 |
| Cupriavidus basilensis FW507-4G11 | 0.86 | RR42_RS14400 | | isopropylmalate isomerase | 0.73 | RR42_RS14320 | | O-succinylhomoserine sulfhydrylase | 0.82 | 12 |
| Castellaniella sp019104865 MT123 | 0.77 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | 0.34 | ABCV34_RS15785 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 48 |
| Variovorax sp. OAS795 | 0.75 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | 0.58 | ABID97_RS21630 | | O-succinylhomoserine sulfhydrylase | — | — |
| Variovorax sp. SCN45 | 0.75 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.56 | GFF3088 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.75 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.60 | GFF301 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.77 | 19 |
| Marinobacter adhaerens HP15 | 0.73 | HP15_1834 | | protein containing 3-isopropylmalate dehydratase, large subunit region domain | 0.55 | HP15_1820 | | methionine gamma-lyase | 0.91 | 10 |
| Kangiella aquimarina DSM 16071 | 0.73 | B158DRAFT_1319 | | 3-isopropylmalate dehydratase, large subunit | 0.40 | B158DRAFT_1522 | | methionine gamma-lyase | low | > 40 |
| Pseudomonas fluorescens FW300-N2C3 | 0.73 | AO356_21400 | | isopropylmalate isomerase | 0.55 | AO356_21470 | | O-succinylhomoserine sulfhydrylase | 0.95 | 5 |
| Pseudomonas sp. RS175 | 0.73 | PFR28_02824 | | 3-isopropylmalate dehydratase large subunit | 0.55 | PFR28_02810 | | O-succinylhomoserine sulfhydrylase | 0.49 | 29 |
| Pseudomonas fluorescens FW300-N2E3 | 0.72 | AO353_20620 | | isopropylmalate isomerase | 0.55 | AO353_20695 | | O-succinylhomoserine sulfhydrylase | 0.95 | 7 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.72 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.33 | Xcc-8004.4517.1 | | Cystathionine gamma-lyase (EC 4.4.1.1) | low | > 74 |
| Pseudomonas fluorescens FW300-N2E2 | 0.72 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.55 | Pf6N2E2_77 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.85 | 8 |
| Pseudomonas stutzeri RCH2 | 0.72 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | 0.54 | Psest_2578 | | O-succinylhomoserine sulfhydrylase | 0.94 | 2 |
| Pseudomonas fluorescens GW456-L13 | 0.72 | PfGW456L13_3948 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.55 | PfGW456L13_3934 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.97 | 4 |
| Pseudomonas syringae pv. syringae B728a | 0.72 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.57 | Psyr_1669 | | O-succinylhomoserine sulfhydrylase | 0.96 | 2 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.72 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.57 | Psyr_1669 | | O-succinylhomoserine sulfhydrylase | 0.94 | 3 |
| Pseudomonas fluorescens FW300-N1B4 | 0.72 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.33 | Pf1N1B4_4890 | | Cystathionine gamma-lyase (EC 4.4.1.1) | low | > 87 |
| Pseudomonas simiae WCS417 | 0.72 | PS417_18600 | | isopropylmalate isomerase | 0.55 | PS417_18530 | | O-succinylhomoserine sulfhydrylase | 0.90 | 10 |
| Pseudomonas putida KT2440 | 0.72 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | 0.53 | PP_2001 | | O-succinylhomoserine sulfhydrylase | 0.88 | 15 |
| Pseudomonas fluorescens SBW25 | 0.71 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.55 | PFLU_RS20510 | | O-succinylhomoserine sulfhydrylase | 0.83 | 6 |
| Pseudomonas fluorescens SBW25-INTG | 0.71 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.55 | PFLU_RS20510 | | O-succinylhomoserine sulfhydrylase | 0.88 | 6 |
| Pseudomonas sp. S08-1 | 0.71 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | 0.56 | OH686_04415 | | O-succinylhomoserine sulfhydrylase | 0.74 | 26 |
| Dechlorosoma suillum PS | 0.70 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | 0.65 | Dsui_3185 | | O-succinylhomoserine sulfhydrylase | — | — |
| Rhodospirillum rubrum S1H | 0.69 | Rru_A1189 | | 3-isopropylmalate dehydratase large subunit region (NCBI) | 0.48 | Rru_A3214 | | O-succinylhomoserine sulfhydrylase (NCBI) | 0.84 | 27 |
| Acinetobacter radioresistens SK82 | 0.68 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | 0.58 | MPMX26_01645 | | O-succinylhomoserine sulfhydrylase | 0.90 | 27 |
| Azospirillum sp. SherDot2 | 0.68 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | 0.46 | MPMX19_01364 | | O-succinylhomoserine sulfhydrylase | 0.90 | 6 |
| Azospirillum brasilense Sp245 | 0.68 | AZOBR_RS03545 | | isopropylmalate isomerase | 0.46 | AZOBR_RS02140 | | O-succinylhomoserine sulfhydrylase | 0.92 | 2 |
| Sinorhizobium meliloti 1021 | 0.66 | SMc03823 | | isopropylmalate isomerase large subunit | 0.45 | SMc02217 | | O-succinylhomoserine sulfhydrylase | 0.97 | 7 |
| Bosea sp. OAE506 | 0.66 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | 0.48 | ABIE41_RS03970 | | O-succinylhomoserine sulfhydrylase | — | — |
| Rhizobium sp. OAE497 | 0.65 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | 0.45 | ABIE40_RS02340 | | O-succinylhomoserine sulfhydrylase | 0.99 | 4 |
| Agrobacterium fabrum C58 | 0.65 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | 0.45 | Atu0432 | | O-succinylhomoserine sulfhydrylase | 0.97 | 6 |
| Rhodopseudomonas palustris CGA009 | 0.64 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | 0.48 | TX73_024775 | | O-succinylhomoserine sulfhydrylase | — | — |
| Magnetospirillum magneticum AMB-1 | 0.64 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | 0.50 | AMB_RS21365 | | O-succinylhomoserine sulfhydrylase | — | — |
| Pantoea sp. MT58 | 0.62 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | 0.28 | IAI47_00880 | | cystathionine gamma-synthase | 0.99 | 2 |
| Enterobacter asburiae PDN3 | 0.62 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | 0.31 | EX28DRAFT_1678 | | Cystathionine beta-lyases/cystathionine gamma-synthases | low | > 76 |
| Escherichia fergusonii Becca | 0.62 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | 0.31 | EFB2_04679 | | Cystathionine gamma-synthase | low | > 86 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.62 | GFF166 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.31 | GFF2323 | | Cystathionine gamma-synthase (EC 2.5.1.48) | low | > 78 |
| Escherichia coli BL21 | 0.62 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | 0.31 | ECD_03825 | | cystathionine gamma-synthase, PLP-dependent | 0.95 | 13 |
| Escherichia coli ECRC62 | 0.62 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | BNILDI_05715 | metB | cystathionine gamma-synthase | 0.98 | 22 |
| Escherichia coli Nissle 1917 | 0.62 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | 0.31 | ECOLIN_RS22725 | | cystathionine gamma-synthase | 0.95 | 10 |
| Escherichia coli ECOR38 | 0.62 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | HEPCGN_12345 | metB | cystathionine gamma-synthase | 0.97 | 33 |
| Escherichia coli ECOR27 | 0.62 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | NOLOHH_05820 | metB | cystathionine gamma-synthase | 0.95 | 22 |
| Escherichia coli BW25113 | 0.62 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | 0.31 | b3939 | metB | cystathionine gamma-synthase (NCBI) | 0.91 | 37 |
| Caulobacter crescentus NA1000 Δfur | 0.62 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.44 | CCNA_02321 | | O-succinylhomoserine sulfhydrylase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.62 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.44 | CCNA_02321 | | O-succinylhomoserine sulfhydrylase | 0.92 | 27 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.62 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | 0.31 | OHPLBJKB_04111 | | Cystathionine gamma-synthase | low | > 73 |
| Dickeya dianthicola ME23 | 0.62 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | 0.31 | DZA65_RS21470 | | cystathionine gamma-synthase | 0.87 | 8 |
| Dickeya dianthicola 67-19 | 0.62 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | 0.31 | HGI48_RS20425 | | cystathionine gamma-synthase | 0.77 | 23 |
| Escherichia coli ECRC101 | 0.61 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | MCAODC_04175 | metB | cystathionine gamma-synthase | 0.94 | 25 |
| Escherichia coli ECRC100 | 0.61 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | OKFHMN_13675 | metB | cystathionine gamma-synthase | 0.98 | 13 |
| Escherichia coli ECRC98 | 0.61 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | JDDGAC_17300 | metB | cystathionine gamma-synthase | 0.99 | 3 |
| Escherichia coli ECRC102 | 0.61 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | NIAGMN_11430 | metB | cystathionine gamma-synthase | — | — |
| Escherichia coli ECRC99 | 0.61 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | KEDOAH_14485 | metB | cystathionine gamma-synthase | — | — |
| Enterobacter sp. TBS_079 | 0.61 | MPMX20_00767 | | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | MPMX20_01953 | | Cystathionine beta-lyase | low | > 85 |
| Klebsiella michiganensis M5al | 0.61 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | 0.32 | BWI76_RS24210 | | cystathionine gamma-lyase | low | > 92 |
| Dickeya dadantii 3937 | 0.61 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | 0.31 | DDA3937_RS00950 | | cystathionine gamma-synthase | 0.74 | 22 |
| Pectobacterium carotovorum WPP14 | 0.61 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | 0.34 | HER17_RS07405 | | PLP-dependent aspartate aminotransferase family protein | low | > 75 |
| Rhodanobacter denitrificans MT42 | 0.60 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | 0.32 | LRK55_RS05410 | | cystathionine gamma-synthase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.60 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | 0.32 | LRK54_RS05660 | | PLP-dependent aspartate aminotransferase family protein | low | > 59 |
| Phaeobacter inhibens DSM 17395 | 0.59 | PGA1_c29780 | | 3-isopropylmalate dehydratase large subunit | 0.49 | PGA1_c23540 | | O-succinylhomoserine sulfhydrylase MetZ | 0.85 | 26 |
| Vibrio cholerae E7946 ATCC 55056 | 0.59 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | 0.27 | CSW01_13550 | | O-succinylhomoserine (thiol)-lyase | low | > 62 |
| Shewanella oneidensis MR-1 | 0.59 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | 0.40 | SO1812 | mdeA | Methionine gamma-lyase (EC 4.4.1.11) (from data) | low | > 76 |
| Shewanella loihica PV-4 | 0.59 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | 0.35 | Shew_2491 | | methionine gamma-lyase (RefSeq) | low | > 60 |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | 0.40 | Shewana3_2643 | | methionine gamma-lyase (RefSeq) | low | > 73 |
| Erwinia tracheiphila SCR3 | 0.58 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | 0.30 | LU632_RS19640 | metB | cystathionine gamma-synthase | 0.80 | 22 |
| Shewanella amazonensis SB2B | 0.58 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | 0.37 | Sama_1242 | | methionine gamma-lyase (RefSeq) | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.58 | Dshi_0085 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | 0.49 | Dshi_2410 | | O-succinylhomoserine sulfhydrylase (RefSeq) | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.58 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | 0.48 | Ga0059261_3194 | | O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) | 0.89 | 56 |
| Mycobacterium tuberculosis H37Rv | 0.57 | Rv2988c | | Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) | 0.47 | Rv0391 | | Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.52 | ABZR88_RS11595 | | 3-isopropylmalate dehydratase large subunit | 0.31 | ABZR88_RS06685 | | cystathionine gamma-synthase | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.51 | CA264_09435 | | 3-isopropylmalate dehydratase large subunit | 0.45 | CA264_02530 | | O-succinylhomoserine sulfhydrylase | low | > 74 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.51 | CA265_RS15830 | | 3-isopropylmalate dehydratase large subunit | 0.46 | CA265_RS13080 | | O-succinylhomoserine sulfhydrylase | 0.93 | 15 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.49 | Echvi_2059 | | 3-isopropylmalate dehydratase, large subunit | 0.48 | Echvi_2283 | | Cystathionine beta-lyases/cystathionine gamma-synthases | 0.72 | 18 |
| Dyella japonica UNC79MFTsu3.2 | 0.49 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | 0.34 | ABZR86_RS18745 | | PLP-dependent aspartate aminotransferase family protein | — | — |
| Lysobacter sp. OAE881 | 0.48 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | 0.33 | ABIE51_RS04295 | | cystathionine gamma-synthase | low | > 62 |
| Rhodanobacter sp. FW510-T8 | 0.47 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | 0.33 | OKGIIK_01180 | metC | cystathionine beta-lyase | low | > 52 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.46 | A4249_RS10005 | | 3-isopropylmalate dehydratase large subunit | 0.34 | A4249_RS08315 | | cystathionine gamma-synthase | low | > 48 |
Not shown: 18 genomes with orthologs for BPHYT_RS33915 only; 1 genomes with orthologs for BPHYT_RS33835 only