Conservation of cofitness between Atu3296 and Atu3298 in Agrobacterium fabrum C58

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu3296 two component response regulator for C4-dicarboxylate transport 1.0 Atu3298 C4-dicarboxylate transporter DctA 0.88 1
Sinorhizobium meliloti 1021 0.70 SM_b20613 C4-dicarboxylate transport transcriptional regulator 0.80 SM_b20611 C4-dicarboxylate transporter DctA 0.81 1
Rhizobium sp. OAE497 0.67 ABIE40_RS26335 sigma-54 dependent transcriptional regulator 0.78 ABIE40_RS26345 dicarboxylate/amino acid:cation symporter 0.93 1
Xanthobacter sp. DMC5 0.61 GFF3675 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.73 GFF3677 C4-dicarboxylate transport protein
Rhodospirillum rubrum S1H 0.56 Rru_A1435 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) 0.75 Rru_A1437 Sodium:dicarboxylate symporter (NCBI) 0.96 1
Castellaniella sp019104865 MT123 0.55 ABCV34_RS02725 sigma-54 dependent transcriptional regulator 0.73 ABCV34_RS02715 dicarboxylate/amino acid:cation symporter low > 48
Azospirillum sp. SherDot2 0.55 MPMX19_04251 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.56 MPMX19_04253 Aerobic C4-dicarboxylate transport protein low > 112
Azospirillum brasilense Sp245 0.53 AZOBR_RS21130 Fis family transcriptional regulator 0.54 AZOBR_RS21140 C4-dicarboxylate ABC transporter 0.50 1
Pseudomonas stutzeri RCH2 0.52 Psest_4132 alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) 0.24 Psest_4075 symporter for L-glutamate, L-glutamine, and L-proline (from data) low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.51 A4249_RS04415 sigma-54 dependent transcriptional regulator 0.68 A4249_RS04425 dicarboxylate/amino acid:cation symporter low > 48
Herbaspirillum seropedicae SmR1 0.51 HSERO_RS16810 Fis family transcriptional regulator 0.57 HSERO_RS13105 C4-dicarboxylate ABC transporter low > 78
Pseudomonas segetis P6 0.50 MPMX49_00215 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.25 MPMX49_00162 Proton/glutamate-aspartate symporter low > 75
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_03805 C4-dicarboxylate ABC transporter 0.57 AO353_02800 C4-dicarboxylate transporter low > 101
Ralstonia sp. UNC404CL21Col 0.49 ABZR87_RS16305 sigma-54 dependent transcriptional regulator 0.59 ABZR87_RS06625 dicarboxylate/amino acid:cation symporter low > 80
Pseudomonas lactucae CFBP13502 0.49 GEMAOFIL_04682 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.61 GEMAOFIL_04444 C4-dicarboxylate transport protein 2 low > 96
Pseudomonas aeruginosa MRSN321 0.49 DY961_RS25855 sigma-54 dependent transcriptional regulator 0.60 DY961_RS06500 dctA;inference=COORDINATES C4-dicarboxylate transporter DctC low > 100
Pseudomonas aeruginosa PUPa3 0.49 DQ20_RS58285 sigma-54 dependent transcriptional regulator 0.60 DQ20_RS46295 dctA;inference=COORDINATES C4-dicarboxylate transporter DctC low > 101
Pseudomonas aeruginosa PA14 0.49 IKLFDK_25855 DNA-binding response regulator 0.60 IKLFDK_05485 C4-dicarboxylate transporter DctC low > 98
Pseudomonas fluorescens FW300-N1B4 0.49 Pf1N1B4_685 Nitrogen regulation protein NR(I) 0.59 Pf1N1B4_3487 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate
Marinobacter adhaerens HP15 0.49 HP15_725 two component, sigma54 specific, transcriptional regulator, Fis family 0.17 HP15_2676 proton/sodium-glutamate symport protein low > 73
Pseudomonas fluorescens GW456-L13 0.49 PfGW456L13_1806 Nitrogen regulation protein NR(I) 0.59 PfGW456L13_2016 C4-dicarboxylate transporter (from data) low > 87
Pseudomonas sp. DMC3 0.49 GFF5041 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.60 GFF4837 C4-dicarboxylate transport protein 2 low > 89
Pseudomonas simiae WCS417 0.48 PS417_22645 C4-dicarboxylate ABC transporter 0.60 PS417_21500 C4 dicarboxylate transporter DctA (from data) low > 88
Pseudomonas orientalis W4I3 0.48 QF045_RS24815 sigma-54 dependent transcriptional regulator 0.61 QF045_RS23590 dicarboxylate/amino acid:cation symporter low > 93
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_09635 sigma-54-dependent Fis family transcriptional regulator 0.19 CSW01_05920 dicarboxylate/amino acid:cation symporter low > 62
Dechlorosoma suillum PS 0.48 Dsui_3486 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains 0.57 Dsui_3158 Na+/H+ dicarboxylate symporter low > 51
Escherichia coli Nissle 1917 0.48 ECOLIN_RS23460 sigma-54 dependent transcriptional regulator 0.61 ECOLIN_RS20180 C4-dicarboxylate transporter DctC low > 55
Escherichia fergusonii Becca 0.48 EFB2_04538 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.61 EFB2_00280 Aerobic C4-dicarboxylate transport protein low > 86
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_17800 C4-dicarboxylate ABC transporter 0.59 AO356_18980 sodium:C4-dicarboxylate symporter (dctA) (from data) low > 104
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS24280 sigma-54-dependent Fis family transcriptional regulator 0.61 PFLU_RS23115 dicarboxylate/amino acid:cation symporter low > 109
Pseudomonas fluorescens SBW25 0.48 PFLU_RS24280 sigma-54-dependent Fis family transcriptional regulator 0.61 PFLU_RS23115 dicarboxylate/amino acid:cation symporter low > 109
Pseudomonas sp. RS175 0.48 PFR28_03462 C4-dicarboxylate transport transcriptional regulatory protein DctD 0.59 PFR28_03241 C4-dicarboxylate transport protein 2 low > 88
Cupriavidus basilensis FW507-4G11 0.48 RR42_RS01705 Fis family transcriptional regulator 0.58 RR42_RS01695 C4-dicarboxylate transporter 0.52 1
Ralstonia solanacearum GMI1000 0.48 RS_RS01635 sigma-54-dependent Fis family transcriptional regulator 0.60 RS_RS01625 C4-dicarboxylate transporter 1 0.43 2
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_5487 Nitrogen regulation protein NR(I) 0.59 Pf6N2E2_5707 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate low > 103
Ralstonia solanacearum PSI07 0.47 RPSI07_RS22520 sigma-54-dependent Fis family transcriptional regulator 0.60 RPSI07_RS22530 dicarboxylate/amino acid:cation symporter 0.57 32
Ralstonia solanacearum UW163 0.47 UW163_RS02785 sigma-54-dependent Fis family transcriptional regulator 0.59 UW163_RS02795 dicarboxylate/amino acid:cation symporter
Ralstonia solanacearum IBSBF1503 0.47 RALBFv3_RS10795 sigma-54-dependent Fis family transcriptional regulator 0.59 RALBFv3_RS10785 dicarboxylate/amino acid:cation symporter 0.52 25
Pseudomonas sp. S08-1 0.47 OH686_13325 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake 0.58 OH686_20585 Na+/H+-dicarboxylate symporter low > 80
Pseudomonas sp. SVBP6 0.47 COO64_RS16760 sigma-54 dependent transcriptional regulator 0.59 COO64_RS07410 dicarboxylate/amino acid:cation symporter low > 93
Paraburkholderia bryophila 376MFSha3.1 0.47 H281DRAFT_02037 two component, sigma54 specific, transcriptional regulator, NtrC subfamily, Fis family 0.59 H281DRAFT_02039 aerobic C4-dicarboxylate transport protein 0.91 1
Pseudomonas putida KT2440 0.47 PP_1066 C4-dicarboxylate transport transcriptional regulatory protein 0.59 PP_1188 C4-dicarboxylate transport protein low > 96
Paraburkholderia graminis OAS925 0.47 ABIE53_000648 two-component system C4-dicarboxylate transport response regulator DctD 0.59 ABIE53_000646 aerobic C4-dicarboxylate transport protein 0.60 2
Pseudomonas sp. BP01 0.47 JOY50_RS14825 sigma-54 dependent transcriptional regulator 0.59 JOY50_RS01965 dicarboxylate/amino acid:cation symporter low > 84
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_3995 Helix-turn-helix, Fis-type 0.60 Psyr_3707 Sodium:dicarboxylate symporter low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_3995 Helix-turn-helix, Fis-type 0.60 Psyr_3707 Sodium:dicarboxylate symporter low > 86
Burkholderia phytofirmans PsJN 0.46 BPHYT_RS02520 Fis family transcriptional regulator 0.59 BPHYT_RS02510 C4-dicarboxylate ABC transporter 0.71 2
Shewanella amazonensis SB2B 0.46 Sama_2213 response regulator receiver protein (RefSeq) 0.27 Sama_2768 proton/glutamate symporter (RefSeq) low > 62
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS01375 sigma-54 dependent transcriptional regulator 0.59 QEN71_RS01365 dicarboxylate/amino acid:cation symporter 0.95 1
Sphingomonas koreensis DSMZ 15582 0.46 Ga0059261_0619 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains 0.64 Ga0059261_0617 Na+/H+-dicarboxylate symporters
Shewanella loihica PV-4 0.45 Shew_1442 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) 0.27 Shew_0743 sodium:dicarboxylate symporter (RefSeq) low > 60
Shewanella oneidensis MR-1 0.45 SO3138 dctD C4-dicarboxylate transport transcriptional regulatory protein (NCBI ptt file) 0.27 SO0922 proton/glutamate symporter (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.45 Shewana3_1412 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) 0.27 Shewana3_3362 sodium:dicarboxylate symporter (RefSeq) low > 73
Variovorax sp. OAS795 0.43 ABID97_RS26605 sigma-54 dependent transcriptional regulator 0.58 ABID97_RS26560 dicarboxylate/amino acid:cation symporter
Variovorax sp. SCN45 0.42 GFF1691 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake 0.57 GFF1694 Na+/H+-dicarboxylate symporter low > 127
Sphingobium sp. HT1-2 0.38 GFF159 hypothetical protein 0.69 GFF161 Na+/H+-dicarboxylate symporter low > 95
Klebsiella michiganensis M5al 0.35 BWI76_RS21250 two-component system response regulator GlrR 0.59 BWI76_RS26760 C4-dicarboxylate transport protein DctA (from data) low > 92
Klebsiella pneumoniae MKP103 0.34 KDGMDA_28370 two-component system response regulator QseF/GlrR 0.58 KDGMDA_07500 C4-dicarboxylate transport protein low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.34 GFF2455 Putative sensory histidine kinase YfhA 0.57 GFF495 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate low > 78
Serratia liquefaciens MT49 0.34 IAI46_19460 two-component system response regulator GlrR 0.59 IAI46_00550 dicarboxylate/amino acid:cation symporter low > 87
Erwinia amylovora T8 0.34 OLJFJH_10330 two-component system response regulator QseF/GlrR 0.57 OLJFJH_04805 C4-dicarboxylate transport protein low > 58
Erwinia tracheiphila HP pepo 2.2 0.34 IJEDHG_02930 qseF two-component system response regulator QseF/GlrR 0.58 IJEDHG_10165 dctA C4-dicarboxylate transport protein low > 61
Pectobacterium carotovorum WPP14 0.34 HER17_RS05925 two-component system response regulator GlrR 0.58 HER17_RS00400 dicarboxylate/amino acid:cation symporter low > 75
Rahnella sp. WP5 0.34 EX31_RS20615 two-component system response regulator GlrR 0.61 EX31_RS05445 dicarboxylate/amino acid:cation symporter low > 89
Erwinia tracheiphila SCR3 0.34 LU632_RS17930 glrR two-component system response regulator GlrR 0.58 LU632_RS00330 dicarboxylate/amino acid:cation symporter low > 73
Dickeya dianthicola ME23 0.34 DZA65_RS16815 two-component system response regulator GlrR 0.59 DZA65_RS21850 dicarboxylate/amino acid:cation symporter low > 75
Dickeya dadantii 3937 0.34 DDA3937_RS15640 two-component system response regulator GlrR 0.57 DDA3937_RS00555 dicarboxylate/amino acid:cation symporter low > 74
Escherichia coli ECOR27 0.33 NOLOHH_13170 qseF two-component system response regulator QseF/GlrR 0.61 NOLOHH_08160 dctA C4-dicarboxylate transporter DctC low > 76
Escherichia coli ECRC62 0.33 BNILDI_11970 qseF two-component system response regulator QseF/GlrR 0.61 BNILDI_03395 dctA C4-dicarboxylate transporter DctC low > 75
Dickeya dianthicola 67-19 0.33 HGI48_RS15735 two-component system response regulator GlrR 0.59 HGI48_RS20835 dicarboxylate/amino acid:cation symporter low > 71
Pantoea agglomerans CFBP13505 P0401 0.33 PagCFBP13505_RS14835 two-component system response regulator GlrR 0.59 PagCFBP13505_RS15580 dicarboxylate/amino acid:cation symporter low > 74
Pantoea sp. MT58 0.33 IAI47_04945 two-component system response regulator GlrR 0.58 IAI47_18585 dicarboxylate/amino acid:cation symporter low > 76
Enterobacter sp. TBS_079 0.33 MPMX20_03423 Transcriptional regulatory protein QseF 0.59 MPMX20_04413 Aerobic C4-dicarboxylate transport protein low > 85
Escherichia coli ECRC99 0.33 KEDOAH_06725 qseF two-component system response regulator QseF/GlrR 0.61 KEDOAH_11955 dctA C4-dicarboxylate transporter DctC
Escherichia coli ECRC101 0.33 MCAODC_12025 qseF two-component system response regulator QseF/GlrR 0.61 MCAODC_06710 dctA C4-dicarboxylate transporter DctC low > 87
Escherichia coli ECRC98 0.33 JDDGAC_25160 qseF two-component system response regulator QseF/GlrR 0.61 JDDGAC_19825 dctA C4-dicarboxylate transporter DctC low > 87
Escherichia coli ECRC100 0.33 OKFHMN_21495 qseF two-component system response regulator QseF/GlrR 0.61 OKFHMN_16195 dctA C4-dicarboxylate transporter DctC low > 79
Enterobacter asburiae PDN3 0.33 EX28DRAFT_0096 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains 0.58 EX28DRAFT_4049 Na+/H+-dicarboxylate symporters low > 76
Escherichia coli ECRC102 0.33 NIAGMN_19265 qseF two-component system response regulator QseF/GlrR 0.61 NIAGMN_13960 dctA C4-dicarboxylate transporter DctC low > 80
Echinicola vietnamensis KMM 6221, DSM 17526 0.32 Echvi_2422 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains 0.20 Echvi_1519 Na+/H+-dicarboxylate symporters low > 79
Rhodanobacter denitrificans MT42 0.32 LRK55_RS11840 sigma-54 dependent transcriptional regulator 0.13 LRK55_RS00475 dicarboxylate/amino acid:cation symporter low > 63
Rhodanobacter denitrificans FW104-10B01 0.32 LRK54_RS12105 sigma-54 dependent transcriptional regulator 0.13 LRK54_RS00700 dicarboxylate/amino acid:cation symporter low > 59
Dyella japonica UNC79MFTsu3.2 0.31 ABZR86_RS04010 sigma-54 dependent transcriptional regulator 0.56 ABZR86_RS08515 dicarboxylate/amino acid:cation symporter low > 74

Not shown: 7 genomes with orthologs for Atu3296 only; 21 genomes with orthologs for Atu3298 only