Conservation of cofitness between Atu3298 and Atu3296 in Agrobacterium fabrum C58

78 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu3298 C4-dicarboxylate transporter DctA 1.0 Atu3296 two component response regulator for C4-dicarboxylate transport 0.88 2
Sinorhizobium meliloti 1021 0.80 SM_b20611 C4-dicarboxylate transporter DctA 0.70 SM_b20613 C4-dicarboxylate transport transcriptional regulator 0.81 2
Rhizobium sp. OAE497 0.78 ABIE40_RS26345 dicarboxylate/amino acid:cation symporter 0.67 ABIE40_RS26335 sigma-54 dependent transcriptional regulator 0.93 1
Rhodospirillum rubrum S1H 0.75 Rru_A1437 Sodium:dicarboxylate symporter (NCBI) 0.56 Rru_A1435 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) 0.96 2
Castellaniella sp019104865 MT123 0.73 ABCV34_RS02715 dicarboxylate/amino acid:cation symporter 0.55 ABCV34_RS02725 sigma-54 dependent transcriptional regulator low > 48
Xanthobacter sp. DMC5 0.73 GFF3677 C4-dicarboxylate transport protein 0.61 GFF3675 C4-dicarboxylate transport transcriptional regulatory protein DctD
Sphingobium sp. HT1-2 0.69 GFF161 Na+/H+-dicarboxylate symporter 0.38 GFF159 hypothetical protein low > 95
Brevundimonas sp. GW460-12-10-14-LB2 0.68 A4249_RS04425 dicarboxylate/amino acid:cation symporter 0.51 A4249_RS04415 sigma-54 dependent transcriptional regulator low > 48
Sphingomonas koreensis DSMZ 15582 0.64 Ga0059261_0617 Na+/H+-dicarboxylate symporters 0.46 Ga0059261_0619 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
Escherichia coli Nissle 1917 0.61 ECOLIN_RS20180 C4-dicarboxylate transporter DctC 0.48 ECOLIN_RS23460 sigma-54 dependent transcriptional regulator low > 55
Escherichia coli ECRC62 0.61 BNILDI_03395 dctA C4-dicarboxylate transporter DctC 0.33 BNILDI_11970 qseF two-component system response regulator QseF/GlrR low > 75
Escherichia coli ECOR27 0.61 NOLOHH_08160 dctA C4-dicarboxylate transporter DctC 0.33 NOLOHH_13170 qseF two-component system response regulator QseF/GlrR low > 76
Escherichia fergusonii Becca 0.61 EFB2_00280 Aerobic C4-dicarboxylate transport protein 0.48 EFB2_04538 C4-dicarboxylate transport transcriptional regulatory protein DctD low > 86
Rahnella sp. WP5 0.61 EX31_RS05445 dicarboxylate/amino acid:cation symporter 0.34 EX31_RS20615 two-component system response regulator GlrR low > 89
Escherichia coli ECRC99 0.61 KEDOAH_11955 dctA C4-dicarboxylate transporter DctC 0.33 KEDOAH_06725 qseF two-component system response regulator QseF/GlrR
Escherichia coli ECRC101 0.61 MCAODC_06710 dctA C4-dicarboxylate transporter DctC 0.33 MCAODC_12025 qseF two-component system response regulator QseF/GlrR low > 88
Escherichia coli ECRC98 0.61 JDDGAC_19825 dctA C4-dicarboxylate transporter DctC 0.33 JDDGAC_25160 qseF two-component system response regulator QseF/GlrR low > 87
Escherichia coli ECRC100 0.61 OKFHMN_16195 dctA C4-dicarboxylate transporter DctC 0.33 OKFHMN_21495 qseF two-component system response regulator QseF/GlrR low > 79
Escherichia coli ECRC102 0.61 NIAGMN_13960 dctA C4-dicarboxylate transporter DctC 0.33 NIAGMN_19265 qseF two-component system response regulator QseF/GlrR low > 80
Pseudomonas lactucae CFBP13502 0.61 GEMAOFIL_04444 C4-dicarboxylate transport protein 2 0.49 GEMAOFIL_04682 C4-dicarboxylate transport transcriptional regulatory protein DctD low > 93
Pseudomonas fluorescens SBW25 0.61 PFLU_RS23115 dicarboxylate/amino acid:cation symporter 0.48 PFLU_RS24280 sigma-54-dependent Fis family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS23115 dicarboxylate/amino acid:cation symporter 0.48 PFLU_RS24280 sigma-54-dependent Fis family transcriptional regulator low > 109
Pseudomonas syringae pv. syringae B728a 0.60 Psyr_3707 Sodium:dicarboxylate symporter 0.47 Psyr_3995 Helix-turn-helix, Fis-type low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.60 Psyr_3707 Sodium:dicarboxylate symporter 0.47 Psyr_3995 Helix-turn-helix, Fis-type low > 86
Pseudomonas simiae WCS417 0.60 PS417_21500 C4 dicarboxylate transporter DctA (from data) 0.48 PS417_22645 C4-dicarboxylate ABC transporter low > 88
Pseudomonas sp. DMC3 0.60 GFF4837 C4-dicarboxylate transport protein 2 0.49 GFF5041 C4-dicarboxylate transport transcriptional regulatory protein DctD low > 89
Pseudomonas aeruginosa PA14 0.60 IKLFDK_05485 C4-dicarboxylate transporter DctC 0.49 IKLFDK_25855 DNA-binding response regulator low > 100
Ralstonia solanacearum GMI1000 0.60 RS_RS01625 C4-dicarboxylate transporter 1 0.48 RS_RS01635 sigma-54-dependent Fis family transcriptional regulator 0.43 8
Ralstonia solanacearum PSI07 0.60 RPSI07_RS22530 dicarboxylate/amino acid:cation symporter 0.47 RPSI07_RS22520 sigma-54-dependent Fis family transcriptional regulator 0.57 80
Pseudomonas fluorescens FW300-N1B4 0.59 Pf1N1B4_3487 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate 0.49 Pf1N1B4_685 Nitrogen regulation protein NR(I)
Pseudomonas putida KT2440 0.59 PP_1188 C4-dicarboxylate transport protein 0.47 PP_1066 C4-dicarboxylate transport transcriptional regulatory protein low > 96
Dickeya dianthicola ME23 0.59 DZA65_RS21850 dicarboxylate/amino acid:cation symporter 0.34 DZA65_RS16815 two-component system response regulator GlrR low > 75
Ralstonia solanacearum IBSBF1503 0.59 RALBFv3_RS10785 dicarboxylate/amino acid:cation symporter 0.47 RALBFv3_RS10795 sigma-54-dependent Fis family transcriptional regulator low > 76
Ralstonia solanacearum UW163 0.59 UW163_RS02795 dicarboxylate/amino acid:cation symporter 0.47 UW163_RS02785 sigma-54-dependent Fis family transcriptional regulator
Dickeya dianthicola 67-19 0.59 HGI48_RS20835 dicarboxylate/amino acid:cation symporter 0.33 HGI48_RS15735 two-component system response regulator GlrR low > 71
Serratia liquefaciens MT49 0.59 IAI46_00550 dicarboxylate/amino acid:cation symporter 0.34 IAI46_19460 two-component system response regulator GlrR low > 86
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS06625 dicarboxylate/amino acid:cation symporter 0.49 ABZR87_RS16305 sigma-54 dependent transcriptional regulator low > 80
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_5707 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate 0.48 Pf6N2E2_5487 Nitrogen regulation protein NR(I) low > 103
Klebsiella michiganensis M5al 0.59 BWI76_RS26760 C4-dicarboxylate transport protein DctA (from data) 0.35 BWI76_RS21250 two-component system response regulator GlrR low > 92
Pseudomonas sp. BP01 0.59 JOY50_RS01965 dicarboxylate/amino acid:cation symporter 0.47 JOY50_RS14825 sigma-54 dependent transcriptional regulator low > 84
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_2016 C4-dicarboxylate transporter (from data) 0.49 PfGW456L13_1806 Nitrogen regulation protein NR(I) low > 87
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_18980 sodium:C4-dicarboxylate symporter (dctA) (from data) 0.48 AO356_17800 C4-dicarboxylate ABC transporter low > 104
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS01365 dicarboxylate/amino acid:cation symporter 0.46 QEN71_RS01375 sigma-54 dependent transcriptional regulator 0.95 2
Pseudomonas sp. SVBP6 0.59 COO64_RS07410 dicarboxylate/amino acid:cation symporter 0.47 COO64_RS16760 sigma-54 dependent transcriptional regulator low > 93
Pseudomonas sp. RS175 0.59 PFR28_03241 C4-dicarboxylate transport protein 2 0.48 PFR28_03462 C4-dicarboxylate transport transcriptional regulatory protein DctD low > 88
Paraburkholderia graminis OAS925 0.59 ABIE53_000646 aerobic C4-dicarboxylate transport protein 0.47 ABIE53_000648 two-component system C4-dicarboxylate transport response regulator DctD 0.60 2
Enterobacter sp. TBS_079 0.59 MPMX20_04413 Aerobic C4-dicarboxylate transport protein 0.33 MPMX20_03423 Transcriptional regulatory protein QseF 0.22 64
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_02039 aerobic C4-dicarboxylate transport protein 0.47 H281DRAFT_02037 two component, sigma54 specific, transcriptional regulator, NtrC subfamily, Fis family 0.91 2
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS02510 C4-dicarboxylate ABC transporter 0.46 BPHYT_RS02520 Fis family transcriptional regulator 0.71 2
Pantoea agglomerans CFBP13505 P0401 0.59 PagCFBP13505_RS15580 dicarboxylate/amino acid:cation symporter 0.33 PagCFBP13505_RS14835 two-component system response regulator GlrR low > 74
Erwinia tracheiphila SCR3 0.58 LU632_RS00330 dicarboxylate/amino acid:cation symporter 0.34 LU632_RS17930 glrR two-component system response regulator GlrR low > 74
Pseudomonas sp. S08-1 0.58 OH686_20585 Na+/H+-dicarboxylate symporter 0.47 OH686_13325 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake low > 80
Erwinia tracheiphila HP pepo 2.2 0.58 IJEDHG_10165 dctA C4-dicarboxylate transport protein 0.34 IJEDHG_02930 qseF two-component system response regulator QseF/GlrR low > 61
Cupriavidus basilensis FW507-4G11 0.58 RR42_RS01695 C4-dicarboxylate transporter 0.48 RR42_RS01705 Fis family transcriptional regulator 0.52 1
Variovorax sp. OAS795 0.58 ABID97_RS26560 dicarboxylate/amino acid:cation symporter 0.43 ABID97_RS26605 sigma-54 dependent transcriptional regulator
Enterobacter asburiae PDN3 0.58 EX28DRAFT_4049 Na+/H+-dicarboxylate symporters 0.33 EX28DRAFT_0096 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains low > 76
Klebsiella pneumoniae MKP103 0.58 KDGMDA_07500 C4-dicarboxylate transport protein 0.34 KDGMDA_28370 two-component system response regulator QseF/GlrR low > 95
Pectobacterium carotovorum WPP14 0.58 HER17_RS00400 dicarboxylate/amino acid:cation symporter 0.34 HER17_RS05925 two-component system response regulator GlrR low > 75
Pantoea sp. MT58 0.58 IAI47_18585 dicarboxylate/amino acid:cation symporter 0.33 IAI47_04945 two-component system response regulator GlrR low > 76
Erwinia amylovora T8 0.57 OLJFJH_04805 C4-dicarboxylate transport protein 0.34 OLJFJH_10330 two-component system response regulator QseF/GlrR low > 58
Dickeya dadantii 3937 0.57 DDA3937_RS00555 dicarboxylate/amino acid:cation symporter 0.34 DDA3937_RS15640 two-component system response regulator GlrR low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.57 GFF495 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate 0.34 GFF2455 Putative sensory histidine kinase YfhA low > 78
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_02800 C4-dicarboxylate transporter 0.50 AO353_03805 C4-dicarboxylate ABC transporter low > 101
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS13105 C4-dicarboxylate ABC transporter 0.51 HSERO_RS16810 Fis family transcriptional regulator low > 78
Dechlorosoma suillum PS 0.57 Dsui_3158 Na+/H+ dicarboxylate symporter 0.48 Dsui_3486 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains low > 51
Variovorax sp. SCN45 0.57 GFF1694 Na+/H+-dicarboxylate symporter 0.42 GFF1691 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake low > 127
Dyella japonica UNC79MFTsu3.2 0.56 ABZR86_RS08515 dicarboxylate/amino acid:cation symporter 0.31 ABZR86_RS04010 sigma-54 dependent transcriptional regulator low > 74
Azospirillum sp. SherDot2 0.56 MPMX19_04253 Aerobic C4-dicarboxylate transport protein 0.55 MPMX19_04251 C4-dicarboxylate transport transcriptional regulatory protein DctD low > 112
Azospirillum brasilense Sp245 0.54 AZOBR_RS21140 C4-dicarboxylate ABC transporter 0.53 AZOBR_RS21130 Fis family transcriptional regulator 0.50 2
Shewanella sp. ANA-3 0.27 Shewana3_3362 sodium:dicarboxylate symporter (RefSeq) 0.45 Shewana3_1412 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) low > 73
Shewanella amazonensis SB2B 0.27 Sama_2768 proton/glutamate symporter (RefSeq) 0.46 Sama_2213 response regulator receiver protein (RefSeq) low > 62
Shewanella oneidensis MR-1 0.27 SO0922 proton/glutamate symporter (NCBI ptt file) 0.45 SO3138 dctD C4-dicarboxylate transport transcriptional regulatory protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.27 Shew_0743 sodium:dicarboxylate symporter (RefSeq) 0.45 Shew_1442 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) low > 60
Pseudomonas stutzeri RCH2 0.24 Psest_4075 symporter for L-glutamate, L-glutamine, and L-proline (from data) 0.52 Psest_4132 alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) low > 67
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_1519 Na+/H+-dicarboxylate symporters 0.32 Echvi_2422 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains low > 79
Vibrio cholerae E7946 ATCC 55056 0.19 CSW01_05920 dicarboxylate/amino acid:cation symporter 0.48 CSW01_09635 sigma-54-dependent Fis family transcriptional regulator low > 62
Marinobacter adhaerens HP15 0.17 HP15_2676 proton/sodium-glutamate symport protein 0.49 HP15_725 two component, sigma54 specific, transcriptional regulator, Fis family low > 73
Rhodanobacter denitrificans FW104-10B01 0.13 LRK54_RS00700 dicarboxylate/amino acid:cation symporter 0.32 LRK54_RS12105 sigma-54 dependent transcriptional regulator low > 59
Rhodanobacter denitrificans MT42 0.13 LRK55_RS00475 dicarboxylate/amino acid:cation symporter 0.32 LRK55_RS11840 sigma-54 dependent transcriptional regulator low > 63

Not shown: 21 genomes with orthologs for Atu3298 only; 7 genomes with orthologs for Atu3296 only