Conservation of cofitness between Atu4000 and Atu3290 in Agrobacterium fabrum C58

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu4000 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1.0 Atu3290 phosphomethylpyrimidine kinase 0.77 8
Rhizobium sp. OAE497 0.69 ABIE40_RS21060 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.43 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Rhodopseudomonas palustris CGA009 0.62 TX73_015405 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.53 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_3674 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.27 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Synechococcus elongatus PCC 7942 0.40 Synpcc7942_0031 bioA aminotransferase 0.30 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase — —
Magnetospirillum magneticum AMB-1 0.40 AMB_RS13895 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.29 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.38 CA265_RS07530 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.40 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 88
Pontibacter actiniarum KMM 6156, DSM 19842 0.38 CA264_02410 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.23 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 74
Azospirillum brasilense Sp245 0.37 AZOBR_RS31120 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.35 AZOBR_RS07045 phosphomethylpyrimidine kinase — —
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS10225 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.36 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.34 Xcc-8004.1559.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.34 Xcc-8004.3091.1 hypothetical protein low > 74
Rhodanobacter sp. FW510-T8 0.34 OKGIIK_11015 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.29 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 52
Ralstonia solanacearum PSI07 0.33 RPSI07_RS16705 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.34 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia graminis OAS925 0.33 ABIE53_000580 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.43 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum GMI1000 0.33 RS_RS07430 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.34 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum UW163 0.33 UW163_RS14150 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.35 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum IBSBF1503 0.33 RALBFv3_RS00815 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.35 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia sp. UNC404CL21Col 0.33 ABZR87_RS12335 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.35 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Desulfovibrio vulgaris Miyazaki F 0.32 DvMF_1002 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (RefSeq) 0.32 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) — —
Fusobacterium nucleatum SB010 0.32 HUW76_05105 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.33 HUW76_10300 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 35
Paraburkholderia bryophila 376MFSha3.1 0.32 H281DRAFT_02094 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.46 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Pseudomonas putida KT2440 0.32 PP_4984 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.27 PP_4782 Phosphomethylpyrimidine kinase 0.43 45
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS02165 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.45 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Pseudomonas stutzeri RCH2 0.32 Psest_0306 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.26 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 67
Pseudomonas fluorescens FW300-N1B4 0.32 Pf1N1B4_2377 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.23 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas sp. S08-1 0.32 OH686_10850 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.26 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD low > 80
Herbaspirillum seropedicae SmR1 0.32 HSERO_RS12250 adenosylmethionine--8-amino-7-oxononanoate aminotransferase 0.24 HSERO_RS02135 phosphomethylpyrimidine kinase low > 78
Pseudomonas fluorescens GW456-L13 0.32 PfGW456L13_1044 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.26 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pectobacterium carotovorum WPP14 0.32 HER17_RS13465 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Pseudomonas syringae pv. syringae B728a ΔmexB 0.32 Psyr_0454 adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme 0.26 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.66 5
Pseudomonas fluorescens FW300-N2E2 0.32 Pf6N2E2_4631 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.23 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 103
Pseudomonas syringae pv. syringae B728a 0.32 Psyr_0454 adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme 0.26 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.66 5
Pseudomonas fluorescens FW300-N2C3 0.32 AO356_13570 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.27 AO356_15435 hydrogenase low > 104
Pseudomonas simiae WCS417 0.31 PS417_26540 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.27 PS417_24600 hydrogenase low > 88
Pseudomonas fluorescens FW300-N2E3 0.31 AO353_08045 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.26 AO353_06350 hydrogenase low > 101
Pseudomonas fluorescens SBW25-INTG 0.31 PFLU_RS28195 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.26 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens SBW25 0.31 PFLU_RS28195 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.26 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Lysobacter sp. OAE881 0.31 ABIE51_RS05265 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.33 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pseudomonas sp. RS175 0.31 PFR28_04208 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.24 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 88
Vibrio cholerae E7946 ATCC 55056 0.31 CSW01_05640 adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA 0.44 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 62
Caulobacter crescentus NA1000 0.30 CCNA_01648 adenosylmethionine-8-amino-7-oxononanoate 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Caulobacter crescentus NA1000 Δfur 0.30 CCNA_01648 adenosylmethionine-8-amino-7-oxononanoate 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Serratia liquefaciens MT49 0.30 IAI46_06520 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS00925 adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA 0.31 RR42_RS01370 phosphomethylpyrimidine kinase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.30 GFF670 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.50 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Dickeya dianthicola 67-19 0.30 HGI48_RS08670 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.48 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.61 62
Enterobacter asburiae PDN3 0.30 EX28DRAFT_2217 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.51 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Paraburkholderia sabiae LMG 24235 0.30 QEN71_RS01100 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.46 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Castellaniella sp019104865 MT123 0.30 ABCV34_RS15300 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.41 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Erwinia tracheiphila SCR3 0.30 LU632_RS09125 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.49 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Rahnella sp. WP5 0.30 EX31_RS23690 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Echinicola vietnamensis KMM 6221, DSM 17526 0.30 Echvi_2790 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.45 Echvi_0215 phosphomethylpyrimidine kinase low > 79
Acinetobacter radioresistens SK82 0.29 MPMX26_02454 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.28 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Dickeya dianthicola ME23 0.29 DZA65_RS08960 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.48 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.72 4
Klebsiella michiganensis M5al 0.29 BWI76_RS08755 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Enterobacter sp. TBS_079 0.29 MPMX20_01402 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.50 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.23 43
Escherichia coli BW25113 0.29 b0774 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase (NCBI) 0.50 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.29 29
Dickeya dadantii 3937 0.29 DDA3937_RS08505 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.49 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Escherichia coli BL21 0.29 ECD_00741 7,8-diaminopelargonic acid synthase, PLP-dependent 0.50 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase low > 60
Variovorax sp. OAS795 0.29 ABID97_RS16265 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.35 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECOR38 0.29 HEPCGN_01635 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.29 OHPLBJKB_02939 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.50 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia fergusonii Becca 0.28 EFB2_03331 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.50 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Escherichia coli Nissle 1917 0.28 ECOLIN_RS04125 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.49 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Dechlorosoma suillum PS 0.28 Dsui_2880 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.27 Dsui_0662 phosphomethylpyrimidine kinase — —
Escherichia coli ECOR27 0.28 NOLOHH_22775 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 57
Escherichia coli ECRC99 0.28 KEDOAH_21505 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.28 OKFHMN_06405 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC98 0.28 JDDGAC_10040 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.28 MCAODC_25620 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC62 0.28 BNILDI_21045 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF3993 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.41 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 90
Escherichia coli ECRC102 0.28 NIAGMN_04450 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.50 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Parabacteroides merdae CL09T00C40 0.28 HMPREF1078_RS15295 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.45 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 61
Acidovorax sp. GW101-3H11 0.28 Ac3H11_3828 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.39 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Phocaeicola vulgatus CL09T03C04 0.28 HMPREF1058_RS17955 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.43 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.76 13
Pantoea sp. MT58 0.27 IAI47_13535 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.47 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Phocaeicola dorei CL03T12C01 0.27 ABI39_RS14245 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.42 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 67
Phaeobacter inhibens DSM 17395 0.27 PGA1_c09150 adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.19 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.40 35
Mycobacterium tuberculosis H37Rv 0.26 Rv1568 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.26 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) — —

Not shown: 10 genomes with orthologs for Atu4000 only; 12 genomes with orthologs for Atu3290 only