Conservation of cofitness between A4249_RS06780 and A4249_RS14985 in Brevundimonas sp. GW460-12-10-14-LB2

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS06780 YicC family protein 1.0 A4249_RS14985 DHA2 family efflux MFS transporter permease subunit 0.57 1
Caulobacter crescentus NA1000 Δfur 0.56 CCNA_01752 YicC-family protein 0.71 CCNA_03831 major facilitator superfamily transporter low > 67
Caulobacter crescentus NA1000 0.56 CCNA_01752 YicC-family protein 0.71 CCNA_03831 major facilitator superfamily transporter low > 66
Azospirillum sp. SherDot2 0.43 MPMX19_00983 hypothetical protein 0.47 MPMX19_04287 Colistin resistance protein EmrB — —
Rhodospirillum rubrum S1H 0.40 Rru_A0428 hypothetical protein (NCBI) 0.43 Rru_A0157 Drug resistance transporter EmrB/QacA subfamily (NCBI) — —
Magnetospirillum magneticum AMB-1 0.38 AMB_RS03835 YicC family protein 0.44 AMB_RS20240 MFS transporter low > 64
Bosea sp. OAE506 0.36 ABIE41_RS17740 YicC/YloC family endoribonuclease 0.45 ABIE41_RS08465 DHA2 family efflux MFS transporter permease subunit low > 77
Sinorhizobium meliloti 1021 0.35 SMc00576 hypothetical protein 0.44 SMc03167 multidrug efflux system protein low > 103
Rhizobium sp. OAE497 0.35 ABIE40_RS06380 YicC/YloC family endoribonuclease 0.38 ABIE40_RS21120 DHA2 family efflux MFS transporter permease subunit low > 107
Agrobacterium fabrum C58 0.34 Atu1100 hypothetical protein 0.46 Atu4479 MFS permease low > 89
Rhodopseudomonas palustris CGA009 0.34 TX73_015880 YicC family protein 0.47 TX73_018360 DHA2 family efflux MFS transporter permease subunit low > 86
Vibrio cholerae E7946 ATCC 55056 0.27 CSW01_01110 YicC family protein 0.20 CSW01_07075 MFS transporter low > 62
Rhodanobacter denitrificans FW104-10B01 0.27 LRK54_RS11750 YicC family protein 0.21 LRK54_RS07790 DHA2 family efflux MFS transporter permease subunit low > 59
Rhodanobacter denitrificans MT42 0.27 LRK55_RS11475 YicC family protein 0.21 LRK55_RS07520 DHA2 family efflux MFS transporter permease subunit low > 63
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_12145 yicC YicC-like family, N-terminal region 0.21 OKGIIK_14290 emrB MFS transporter — —
Marinobacter adhaerens HP15 0.26 HP15_301 conserved hypothetical protein 0.12 HP15_3822 drug resistance transporter, EmrB/QacA family low > 73
Dyella japonica UNC79MFTsu3.2 0.26 ABZR86_RS11895 YicC/YloC family endoribonuclease 0.36 ABZR86_RS03385 DHA2 family efflux MFS transporter permease subunit low > 74
Shewanella amazonensis SB2B 0.26 Sama_0319 hypothetical protein (RefSeq) 0.27 Sama_0403 drug resistance transporter, EmrB/QacA family protein (RefSeq) low > 62
Shewanella sp. ANA-3 0.26 Shewana3_3778 hypothetical protein (RefSeq) 0.29 Shewana3_0523 EmrB/QacA family drug resistance transporter (RefSeq) low > 73
Shewanella oneidensis MR-1 0.25 SO4257 conserved hypothetical protein TIGR00255 (NCBI ptt file) 0.28 SO0525 drug resistance transporter, EmrB/QacA family protein (NCBI ptt file) low > 76
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4364 Protein YicC 0.23 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system 0.22 23
Pseudomonas sp. S08-1 0.25 OH686_13565 UPF0701 protein YicC 0.26 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system low > 80
Pseudomonas simiae WCS417 0.24 PS417_27815 hypothetical protein 0.23 PS417_16910 multidrug resistance protein B low > 88
Pseudomonas fluorescens GW456-L13 0.24 PfGW456L13_783 Protein YicC 0.35 PfGW456L13_2409 Inner membrane component of tripartite multidrug resistance system low > 87
Pantoea sp. MT58 0.24 IAI47_00580 YicC family protein 0.21 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB low > 76
Pseudomonas sp. RS175 0.24 PFR28_04421 hypothetical protein 0.23 PFR28_02747 Multidrug export protein EmrB — —
Pseudomonas fluorescens FW300-N2E3 0.24 AO353_09265 hypothetical protein 0.34 AO353_19715 disulfide bond formation protein DsbA low > 101
Pseudomonas fluorescens FW300-N1B4 0.24 Pf1N1B4_2116 Protein YicC 0.34 Pf1N1B4_122 Inner membrane component of tripartite multidrug resistance system — —
Erwinia tracheiphila SCR3 0.24 LU632_RS22050 YicC family protein 0.20 LU632_RS09490 DHA2 family efflux MFS transporter permease subunit low > 74
Dickeya dadantii 3937 0.24 DDA3937_RS20645 YicC family protein 0.20 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB low > 74
Pectobacterium carotovorum WPP14 0.24 HER17_RS20905 YicC family protein 0.22 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB low > 75
Shewanella loihica PV-4 0.24 Shew_3489 hypothetical protein (RefSeq) 0.27 Shew_3405 EmrB/QacA family drug resistance transporter (RefSeq) low > 60
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_12495 hypothetical protein 0.23 AO356_01025 multidrug resistance protein B low > 104
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0212 Conserved hypothetical protein 255 0.22 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0212 Conserved hypothetical protein 255 0.22 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Serratia liquefaciens MT49 0.24 IAI46_24855 YicC family protein 0.21 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB low > 86
Enterobacter sp. TBS_079 0.24 MPMX20_00091 hypothetical protein 0.23 MPMX20_03564 Multidrug export protein EmrB low > 85
Cupriavidus basilensis FW507-4G11 0.24 RR42_RS04905 hypothetical protein 0.37 RR42_RS27155 DSBA oxidoreductase — —
Pseudomonas fluorescens SBW25 0.23 PFLU_RS29495 YicC family protein 0.23 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Dickeya dianthicola ME23 0.23 DZA65_RS00575 YicC family protein 0.21 DZA65_RS17910 multidrug efflux MFS transporter permease subunit EmrB low > 75
Pseudomonas putida KT2440 0.23 PP_5295 conserved protein of unknown function 0.26 PP_1975 putative EmrB/QacA family drug resistance transporter low > 96
Klebsiella michiganensis M5al 0.23 BWI76_RS27395 hypothetical protein 0.22 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB low > 92
Pseudomonas fluorescens SBW25-INTG 0.23 PFLU_RS29495 YicC family protein 0.23 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Lysobacter sp. OAE881 0.23 ABIE51_RS17280 YicC/YloC family endoribonuclease 0.25 ABIE51_RS07705 DHA2 family efflux MFS transporter permease subunit low > 62
Dickeya dianthicola 67-19 0.23 HGI48_RS00540 YicC family protein 0.21 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB low > 71
Escherichia coli BL21 0.23 ECD_03501 UPF0701 family protein 0.22 ECD_02541 multidrug efflux system protein low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.23 OHPLBJKB_00058 hypothetical protein 0.22 OHPLBJKB_01047 Multidrug export protein EmrB low > 73
Escherichia coli ECRC62 0.23 BNILDI_04050 yicC UPF0701 protein YicC 0.22 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli ECOR38 0.23 HEPCGN_14405 yicC UPF0701 protein YicC 0.22 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli ECRC99 0.23 KEDOAH_12560 yicC UPF0701 protein YicC 0.22 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli ECRC102 0.23 NIAGMN_13345 yicC UPF0701 protein YicC 0.22 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli ECRC98 0.23 JDDGAC_19210 yicC UPF0701 protein YicC 0.22 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB low > 86
Escherichia coli ECOR27 0.23 NOLOHH_07465 yicC UPF0701 protein YicC 0.22 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB 0.61 13
Escherichia coli ECRC101 0.23 MCAODC_06095 yicC UPF0701 protein YicC 0.22 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli Nissle 1917 0.23 ECOLIN_RS20760 YicC/YloC family endoribonuclease 0.22 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB low > 55
Escherichia coli ECRC100 0.23 OKFHMN_15585 yicC UPF0701 protein YicC 0.22 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB low > 80
Escherichia coli BW25113 0.23 b3644 yicC hypothetical protein (NCBI) 0.22 b2686 emrB multidrug efflux system protein (NCBI) low > 76
Escherichia fergusonii Becca 0.23 EFB2_00169 hypothetical protein 0.31 EFB2_02589 Colistin resistance protein EmrB low > 86
Herbaspirillum seropedicae SmR1 0.23 HSERO_RS10650 hypothetical protein 0.24 HSERO_RS15980 DSBA oxidoreductase low > 78
Ralstonia solanacearum IBSBF1503 0.23 RALBFv3_RS03330 YicC family protein 0.22 RALBFv3_RS15695 MFS transporter low > 76
Ralstonia solanacearum GMI1000 0.23 RS_RS10815 YicC family protein 0.22 RS_RS13645 EmrB/QacA family drug resistance transporter — —
Ralstonia solanacearum UW163 0.23 UW163_RS10390 YicC family protein 0.21 UW163_RS07870 MFS transporter — —
Rahnella sp. WP5 0.22 EX31_RS14510 YicC family protein 0.34 EX31_RS10775 DHA2 family efflux MFS transporter permease subunit low > 89
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.22 GFF365 Protein YicC 0.22 GFF1593 Multidrug resistance protein B low > 78
Xanthomonas campestris pv. campestris strain 8004 0.22 Xcc-8004.1220.1 Protein YicC 0.27 Xcc-8004.2208.1 Inner membrane component of tripartite multidrug resistance system low > 74
Ralstonia solanacearum PSI07 0.22 RPSI07_RS13855 YicC family protein 0.22 RPSI07_RS11545 EmrB/QacA family drug resistance transporter low > 81
Variovorax sp. OAS795 0.22 ABID97_RS23655 YicC/YloC family endoribonuclease 0.21 ABID97_RS20390 DHA2 family efflux MFS transporter permease subunit low > 91
Enterobacter asburiae PDN3 0.22 EX28DRAFT_3894 TIGR00255 family protein 0.23 EX28DRAFT_2769 drug resistance transporter, EmrB/QacA subfamily 0.62 34
Variovorax sp. SCN45 0.22 GFF2378 UPF0701 protein YicC 0.22 GFF4771 Multidrug efflux system EmrAB-OMF, inner-membrane proton/drug antiporter EmrB (MFS type) — —
Ralstonia sp. UNC404CL21Col 0.21 ABZR87_RS15240 YicC/YloC family endoribonuclease 0.21 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit low > 80
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_14585 YicC family protein 0.27 CA264_07170 MFS transporter low > 74
Acidovorax sp. GW101-3H11 0.21 Ac3H11_3667 Protein YicC 0.21 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system — —
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS15320 hypothetical protein 0.35 BPHYT_RS21945 DSBA oxidoreductase low > 109
Paraburkholderia graminis OAS925 0.20 ABIE53_003233 uncharacterized protein (TIGR00255 family) 0.35 ABIE53_005460 DHA2 family multidrug resistance protein low > 113
Paraburkholderia bryophila 376MFSha3.1 0.20 H281DRAFT_04007 TIGR00255 family protein 0.36 H281DRAFT_03096 drug resistance transporter, EmrB/QacA subfamily low > 103
Paraburkholderia sabiae LMG 24235 0.20 QEN71_RS03650 YicC/YloC family endoribonuclease 0.36 QEN71_RS18310 DHA2 family efflux MFS transporter permease subunit low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.19 GFF3251 Protein YicC 0.22 GFF3757 Inner membrane component of tripartite multidrug resistance system — —
Castellaniella sp019104865 MT123 0.19 ABCV34_RS03510 DUF1732 domain-containing protein 0.21 ABCV34_RS13880 DHA2 family efflux MFS transporter permease subunit low > 48
Desulfovibrio vulgaris Miyazaki F 0.19 DvMF_1140 hypothetical protein (RefSeq) 0.24 DvMF_1099 drug resistance transporter, EmrB/QacA subfamily (RefSeq) low > 51
Mucilaginibacter yixingensis YX-36 DSM 26809 0.18 ABZR88_RS01665 YicC/YloC family endoribonuclease 0.26 ABZR88_RS20975 DHA2 family efflux MFS transporter permease subunit — —
Pedobacter sp. GW460-11-11-14-LB5 0.17 CA265_RS18780 YicC family protein 0.26 CA265_RS21345 MFS transporter low > 88

Not shown: 16 genomes with orthologs for A4249_RS06780 only; 2 genomes with orthologs for A4249_RS14985 only