Conservation of cofitness between b0907 and b3941 in Escherichia coli BW25113

78 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0907 serC phosphoserine aminotransferase (NCBI) 1.0 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.91 7
Escherichia coli BL21 1.00 ECD_00911 3-phosphoserine/phosphohydroxythreonine aminotransferase 1.00 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.60 33
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02761 Phosphoserine aminotransferase 1.00 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase
Escherichia coli ECRC62 1.00 BNILDI_20305 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 BNILDI_05725 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC98 1.00 JDDGAC_09100 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 JDDGAC_17290 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC99 1.00 KEDOAH_22245 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 KEDOAH_14495 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC102 1.00 NIAGMN_03210 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 NIAGMN_11420 metF methylenetetrahydrofolate reductase
Escherichia coli ECOR27 1.00 NOLOHH_22050 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 NOLOHH_05810 metF methylenetetrahydrofolate reductase low > 57
Escherichia coli ECRC101 1.00 OKFHMN_05490 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 OKFHMN_13665 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC101 1.00 MCAODC_24880 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 MCAODC_04165 metF methylenetetrahydrofolate reductase
Escherichia coli ECOR38 0.99 HEPCGN_23030 serC 3-phosphoserine/phosphohydroxythreonine transaminase 1.00 HEPCGN_12310 metF methylenetetrahydrofolate reductase low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04805 3-phosphoserine/phosphohydroxythreonine transaminase 0.99 ECOLIN_RS22760 methylenetetrahydrofolate reductase low > 52
Escherichia fergusonii Becca 0.99 EFB2_03157 Phosphoserine aminotransferase 0.99 EFB2_04672 5,10-methylenetetrahydrofolate reductase low > 86
Enterobacter sp. TBS_079 0.93 MPMX20_01566 Phosphoserine aminotransferase 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.72 67
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF3664 Phosphoserine aminotransferase (EC 2.6.1.52) 0.97 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 78
Enterobacter asburiae PDN3 0.91 EX28DRAFT_2028 phosphoserine aminotransferase apoenzyme (EC 2.6.1.52) 0.94 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Klebsiella michiganensis M5al 0.89 BWI76_RS09755 phosphoserine transaminase 0.95 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.82 33
Pantoea sp. MT58 0.82 IAI47_12865 3-phosphoserine/phosphohydroxythreonine transaminase 0.92 IAI47_00890 methylenetetrahydrofolate reductase low > 76
Erwinia tracheiphila SCR3 0.81 LU632_RS09790 serC 3-phosphoserine/phosphohydroxythreonine transaminase 0.86 LU632_RS19630 metF methylenetetrahydrofolate reductase
Dickeya dadantii 3937 0.81 DDA3937_RS09670 3-phosphoserine/phosphohydroxythreonine transaminase 0.90 DDA3937_RS00960 methylenetetrahydrofolate reductase low > 74
Pectobacterium carotovorum WPP14 0.80 HER17_RS12290 3-phosphoserine/phosphohydroxythreonine transaminase 0.88 HER17_RS00950 methylenetetrahydrofolate reductase
Dickeya dianthicola 67-19 0.80 HGI48_RS09680 3-phosphoserine/phosphohydroxythreonine transaminase 0.88 HGI48_RS20415 methylenetetrahydrofolate reductase
Dickeya dianthicola ME23 0.79 DZA65_RS09990 3-phosphoserine/phosphohydroxythreonine transaminase 0.88 DZA65_RS21460 methylenetetrahydrofolate reductase low > 75
Serratia liquefaciens MT49 0.79 IAI46_08635 3-phosphoserine/phosphohydroxythreonine transaminase 0.91 IAI46_24530 methylenetetrahydrofolate reductase low > 86
Rahnella sp. WP5 0.79 EX31_RS18255 3-phosphoserine/phosphohydroxythreonine transaminase 0.89 EX31_RS14205 methylenetetrahydrofolate reductase low > 89
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_05875 3-phosphoserine/phosphohydroxythreonine transaminase 0.79 CSW01_13560 methylenetetrahydrofolate reductase
Alteromonas macleodii MIT1002 0.59 MIT1002_02192 Phosphoserine aminotransferase 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase
Shewanella sp. ANA-3 0.58 Shewana3_1973 phosphoserine aminotransferase (RefSeq) 0.75 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq)
Pseudomonas stutzeri RCH2 0.57 Psest_1983 phosphoserine aminotransferase 0.35 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Acinetobacter radioresistens SK82 0.56 MPMX26_02219 Phosphoserine aminotransferase 0.31 MPMX26_01002 5,10-methylenetetrahydrofolate reductase
Shewanella oneidensis MR-1 0.56 SO2410 serC phosphoserine aminotransferase (NCBI ptt file) 0.75 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file)
Pseudomonas putida KT2440 0.56 PP_1768 phosphoserine aminotransferase 0.36 PP_4977 5,10-methylenetetrahydrofolate reductase
Pseudomonas sp. RS175 0.56 PFR28_00906 Phosphoserine aminotransferase 0.36 PFR28_04202 5,10-methylenetetrahydrofolate reductase
Shewanella amazonensis SB2B 0.56 Sama_1732 phosphoserine aminotransferase (RefSeq) 0.75 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq)
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_02075 3-phosphoserine/phosphohydroxythreonine aminotransferase 0.35 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.83 27
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_2175 Phosphoserine aminotransferase (EC 2.6.1.52) 0.35 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Shewanella loihica PV-4 0.56 Shew_1950 phosphoserine aminotransferase (RefSeq) 0.76 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq)
Pseudomonas fluorescens FW300-N2C3 0.55 AO356_03470 3-phosphoserine/phosphohydroxythreonine aminotransferase 0.35 AO356_13605 5,10-methylenetetrahydrofolate reductase
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_2521 Phosphoserine aminotransferase (EC 2.6.1.52) 0.36 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas simiae WCS417 0.55 PS417_08120 MFS transporter 0.36 PS417_26510 5,10-methylenetetrahydrofolate reductase
Pseudomonas sp. S08-1 0.55 OH686_20865 phosphoserine transaminase 0.36 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H]
Pseudomonas fluorescens SBW25 0.55 PFLU_RS08090 3-phosphoserine/phosphohydroxythreonine transaminase 0.36 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H]
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_03926 phosphoserine aminotransferase apoenzyme 0.40 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P)) 0.66 20
Pseudomonas fluorescens SBW25-INTG 0.55 PFLU_RS08090 3-phosphoserine/phosphohydroxythreonine transaminase 0.36 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H]
Burkholderia phytofirmans PsJN 0.55 BPHYT_RS14915 phosphoserine aminotransferase 0.38 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase 0.53 98
Pseudomonas syringae pv. syringae B728a 0.55 Psyr_3646 phosphoserine aminotransferase apoenzyme 0.35 Psyr_0459 5,10-methylenetetrahydrofolate reductase
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS18435 MFS transporter 0.35 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.55 Psyr_3646 phosphoserine aminotransferase apoenzyme 0.35 Psyr_0459 5,10-methylenetetrahydrofolate reductase
Dechlorosoma suillum PS 0.54 Dsui_1939 phosphoserine aminotransferase 0.38 Dsui_0640 5,10-methylenetetrahydrofolate reductase
Paraburkholderia sabiae LMG 24235 0.54 QEN71_RS04065 3-phosphoserine/phosphohydroxythreonine transaminase 0.41 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.91 23
Lysobacter sp. OAE881 0.54 ABIE51_RS12150 3-phosphoserine/phosphohydroxythreonine transaminase 0.34 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.96 25
Ralstonia solanacearum UW163 0.52 UW163_RS16055 3-phosphoserine/phosphohydroxythreonine transaminase 0.38 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H]
Marinobacter adhaerens HP15 0.52 HP15_1361 phosphoserine aminotransferase 0.37 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein
Ralstonia solanacearum IBSBF1503 0.52 RALBFv3_RS13755 3-phosphoserine/phosphohydroxythreonine transaminase 0.38 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.83 9
Ralstonia solanacearum GMI1000 0.52 RS_RS04490 3-phosphoserine/phosphohydroxythreonine aminotransferase 0.38 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H] 0.82 5
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF5342 Phosphoserine aminotransferase (EC 2.6.1.52) 0.34 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Rhodanobacter denitrificans MT42 0.52 LRK55_RS00140 3-phosphoserine/phosphohydroxythreonine transaminase 0.35 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] low > 63
Dyella japonica UNC79MFTsu3.2 0.52 ABZR86_RS02220 3-phosphoserine/phosphohydroxythreonine transaminase 0.35 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.95 20
Rhodanobacter denitrificans FW104-10B01 0.52 LRK54_RS00400 3-phosphoserine/phosphohydroxythreonine transaminase 0.35 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.59 51
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_06910 serC 3-phosphoserine/phosphohydroxythreonine transaminase 0.35 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] low > 52
Ralstonia solanacearum PSI07 0.51 RPSI07_RS19715 3-phosphoserine/phosphohydroxythreonine transaminase 0.38 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.74 20
Kangiella aquimarina DSM 16071 0.51 B158DRAFT_2322 phosphoserine aminotransferase apoenzyme (EC 2.6.1.52) 0.59 B158DRAFT_2461 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20)
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS09445 3-phosphoserine/phosphohydroxythreonine transaminase 0.37 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H] 0.71 37
Acidovorax sp. GW101-3H11 0.50 Ac3H11_2573 Phosphoserine aminotransferase (EC 2.6.1.52) 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Variovorax sp. SCN45 0.50 GFF6183 Phosphoserine aminotransferase (EC 2.6.1.52) 0.32 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS04455 MFS transporter 0.38 RR42_RS01385 5,10-methylenetetrahydrofolate reductase
Castellaniella sp019104865 MT123 0.49 ABCV34_RS07115 3-phosphoserine/phosphohydroxythreonine transaminase 0.34 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H]
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.3283.1 Phosphoserine aminotransferase (EC 2.6.1.52) 0.36 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 74
Variovorax sp. OAS795 0.46 ABID97_RS09520 3-phosphoserine/phosphohydroxythreonine transaminase 0.33 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H]
Paraburkholderia graminis OAS925 0.46 ABIE53_003159 phosphoserine aminotransferase 0.39 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH) 0.87 11
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_351 Phosphoserine aminotransferase (EC 2.6.1.52) 0.35 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pedobacter sp. GW460-11-11-14-LB5 0.44 CA265_RS09005 phosphoserine transaminase 0.21 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H]
Bacteroides thetaiotaomicron VPI-5482 0.40 BT1153 phosphoserine aminotransferase (NCBI ptt file) 0.18 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) low > 81
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS09230 3-phosphoserine/phosphohydroxythreonine transaminase 0.22 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H]
Bacteroides ovatus ATCC 8483 0.39 BACOVA_04029 phosphoserine transaminase 0.15 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) low > 94
Bacteroides stercoris CC31F 0.39 HMPREF1181_RS16870 3-phosphoserine/phosphohydroxythreonine transaminase 0.17 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H]
Phocaeicola dorei CL03T12C01 0.38 ABI39_RS16905 3-phosphoserine/phosphohydroxythreonine transaminase 0.19 ABI39_RS15570 methylenetetrahydrofolate reductase [NAD(P)H] low > 72
Phocaeicola vulgatus CL09T03C04 0.38 HMPREF1058_RS04300 3-phosphoserine/phosphohydroxythreonine transaminase 0.18 HMPREF1058_RS01490 methylenetetrahydrofolate reductase [NAD(P)H] low > 67
Parabacteroides merdae CL09T00C40 0.38 HMPREF1078_RS15400 3-phosphoserine/phosphohydroxythreonine transaminase 0.21 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] low > 61

Not shown: 1 genomes with orthologs for b0907 only; 21 genomes with orthologs for b3941 only