| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Variovorax sp. SCN45 | GFF4530 | | MBL-fold metallo-hydrolase superfamily | cofit | 100 | 100 |
| o | Variovorax sp. OAS795 | ABID97_RS06095 | | MBL fold metallo-hydrolase | cofit | 81 | 100 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF537 | | Metallo-beta-lactamase family protein | insig. | 69 | 97 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_1985 | | Metallo-beta-lactamase family protein | insig. | 69 | 99 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF868 | | Metallo-beta-lactamase family protein | insig. | 61 | 83 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS09265 | | NUDIX hydrolase | insig. | 39 | 94 |
| o | Marinobacter adhaerens HP15 | HP15_3568 | | beta-lactamase domain protein | cofit | 37 | 96 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0054 | | Zn-dependent hydrolases, including glyoxylases | cofit | 38 | 47 |
| | Sphingobium sp. HT1-2 | GFF248 | | MBL-fold metallo-hydrolase superfamily | cofit | 37 | 47 |
| | Variovorax sp. SCN45 | GFF2447 | | beta-lactamase-like protein | insig. | 32 | 78 |
| | Caulobacter crescentus NA1000 | CCNA_00971 | | hydroxyacylglutathione hydrolase | cofit | 38 | 47 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00971 | | hydroxyacylglutathione hydrolase | cofit | 38 | 47 |
| | Rhizobium sp. OAE497 | ABIE40_RS04350 | | MBL fold metallo-hydrolase | strong | 38 | 48 |
| | Xanthobacter sp. DMC5 | GFF4267 | | Hydroxyacylglutathione hydrolase | strong | 37 | 47 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS07955 | | MBL fold metallo-hydrolase | strong | 36 | 47 |
| | Agrobacterium fabrum C58 | Atu0807 | | metallo-beta-lactamase superfamily protein | strong | 34 | 50 |
| | Bosea sp. OAE506 | ABIE41_RS10145 | | MBL fold metallo-hydrolase | strong | 39 | 42 |
| | Rhodopseudomonas palustris CGA009 | TX73_016495 | | NUDIX hydrolase | insig. | 41 | 37 |
| | Sinorhizobium meliloti 1021 | SMc00087 | | hydrolase | strong | 33 | 49 |
| | Rhodopseudomonas palustris CGA009 | TX73_005630 | | MBL fold metallo-hydrolase | strong | 35 | 46 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1920 | | beta-lactamase domain protein (RefSeq) | insig. | 33 | 49 |
| | Variovorax sp. OAS795 | ABID97_RS12035 | | NUDIX domain-containing protein | insig. | 30 | 59 |
| | Azospirillum sp. SherDot2 | MPMX19_04459 | | hypothetical protein | insig. | 37 | 36 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c13050 | | Zn-dependent hydrolases, including glyoxylases | strong | 31 | 48 |
| | Caulobacter crescentus NA1000 | CCNA_02407 | | hydrolase, nudix family | insig. | 42 | 35 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02407 | | hydrolase, nudix family | insig. | 42 | 35 |
| | Azospirillum brasilense Sp245 | AZOBR_RS07985 | | NUDIX hydrolase | no data | 40 | 36 |
| | Mycobacterium tuberculosis H37Rv | Rv3677c | | Possible hydrolase | insig. | 32 | 47 |
| | Mycobacterium tuberculosis H37Rv | Rv3040c | | Conserved protein | insig. | 34 | 36 |
| | Sphingobium sp. HT1-2 | GFF2373 | | hypothetical protein | cofit | 38 | 37 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF789 | | hypothetical protein | insig. | 35 | 37 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1068 | | NUDIX domain | insig. | 34 | 35 |
| | Marinobacter adhaerens HP15 | HP15_1191 | | metallo-beta-lactamase family protein | insig. | 32 | 31 |
| | Bosea sp. OAE506 | ABIE41_RS18150 | | NUDIX hydrolase | insig. | 32 | 30 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06415 | | MBL fold metallo-hydrolase | insig. | 31 | 31 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3684 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 28 | 32 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS04560 | | MBL fold metallo-hydrolase | cofit | 30 | 32 |
| | Ralstonia solanacearum GMI1000 | RS_RS01380 | | Zn-dependent hydrolase | insig. | 39 | 19 |
| | Rhizobium sp. OAE497 | ABIE40_RS12965 | | MBL fold metallo-hydrolase | insig. | 29 | 27 |
| | Pantoea sp. MT58 | IAI47_12770 | | MBL fold metallo-hydrolase | sig. | 30 | 28 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2009 | | Zn-dependent hydrolases, including glyoxylases | insig. | 29 | 32 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS22775 | | Zn-dependent hydrolase | insig. | 38 | 19 |
| | Azospirillum sp. SherDot2 | MPMX19_06029 | | Hydroxyacylglutathione hydrolase GloB | insig. | 31 | 34 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c08480 | | NUDIX hydrolase-like protein | insig. | 31 | 27 |
| | Escherichia coli ECOR38 | HEPCGN_23135 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 28 | 32 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS08720 | | MBL fold metallo-hydrolase | no data | 30 | 31 |
| | Rhizobium sp. OAE497 | ABIE40_RS17605 | | hydroxyacylglutathione hydrolase | insig. | 30 | 33 |
| | Shewanella loihica PV-4 | Shew_2269 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 30 | 31 |
| | Caulobacter crescentus NA1000 | CCNA_02541 | | MutT/nudix family phosphohydrolase | insig. | 33 | 26 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02541 | | MutT/nudix family phosphohydrolase | insig. | 33 | 26 |
| | Enterobacter sp. TBS_079 | MPMX20_01585 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 32 |
| | Ralstonia solanacearum GMI1000 | RS_RS16370 | | MBL fold metallo-hydrolase | no data | 30 | 31 |
| | Sinorhizobium meliloti 1021 | SMc01587 | | hypothetical protein | insig. | 29 | 29 |
| | Escherichia fergusonii Becca | EFB2_03137 | | Hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Escherichia coli ECRC100 | OKFHMN_05390 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Escherichia coli ECRC101 | MCAODC_24780 | gloC | hydroxyacylglutathione hydrolase GloC | sig. | 27 | 32 |
| | Escherichia coli ECRC102 | NIAGMN_03110 | gloC | hydroxyacylglutathione hydrolase GloC | cofit | 27 | 32 |
| | Escherichia coli ECRC98 | JDDGAC_09000 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Escherichia coli ECRC99 | KEDOAH_22345 | gloC | hydroxyacylglutathione hydrolase GloC | no data | 27 | 32 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS04905 | | hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Xanthobacter sp. DMC5 | GFF1083 | | hypothetical protein | insig. | 32 | 26 |
| | Dechlorosoma suillum PS | Dsui_3107 | | Zn-dependent hydrolase, glyoxylase | insig. | 30 | 27 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS20090 | | Zn-dependent hydrolase | insig. | 30 | 34 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS08330 | | NUDIX domain-containing protein | insig. | 33 | 30 |
| | Agrobacterium fabrum C58 | Atu3614 | | glyoxalase II | sig. | 31 | 32 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS03825 | | MBL fold metallo-hydrolase | insig. | 30 | 26 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS08505 | | MBL fold metallo-hydrolase | no data | 29 | 33 |
| | Ralstonia solanacearum UW163 | UW163_RS05105 | | MBL fold metallo-hydrolase | no data | 29 | 33 |
| | Escherichia coli BL21 | ECD_00931 | | putative metal-binding enzyme | insig. | 27 | 32 |
| | Escherichia coli BW25113 | b0927 | ycbL | predicted metal-binding enzyme (NCBI) | sig. | 27 | 32 |
| | Pseudomonas sp. BP01 | JOY50_RS13905 | | MBL fold metallo-hydrolase | insig. | 25 | 40 |
| | Xanthobacter sp. DMC5 | GFF3817 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 33 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS10540 | | Zn-dependent hydrolase | insig. | 37 | 18 |
| | Ralstonia solanacearum UW163 | UW163_RS03040 | | Zn-dependent hydrolase | insig. | 37 | 18 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2822 | | NUDIX hydrolase (RefSeq) | no data | 35 | 27 |
| | Serratia liquefaciens MT49 | IAI46_08745 | | MBL fold metallo-hydrolase | insig. | 28 | 27 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2827 | | Zn-dependent hydrolases, including glyoxylases | insig. | 26 | 29 |
| | Escherichia coli ECOR27 | NOLOHH_21950 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Escherichia coli ECRC62 | BNILDI_20205 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02740 | | Hydroxyacylglutathione hydrolase GloC | insig. | 27 | 32 |
| | Pectobacterium carotovorum WPP14 | HER17_RS12035 | | MBL fold metallo-hydrolase | insig. | 29 | 27 |
| | Fusobacterium nucleatum SB010 | HUW76_06550 | | MBL fold metallo-hydrolase | strong | 26 | 30 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS02250 | | Zn-dependent hydrolase | insig. | 32 | 19 |
| | Paraburkholderia graminis OAS925 | ABIE53_000594 | | glyoxylase-like metal-dependent hydrolase (beta-lactamase superfamily II) | insig. | 32 | 19 |
| | Azospirillum sp. SherDot2 | MPMX19_04818 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 31 |
| | Paraburkholderia graminis OAS925 | ABIE53_000468 | | hydroxyacylglutathione hydrolase | sig. | 28 | 29 |
| | Methanococcus maripaludis JJ | MMJJ_RS04795 | | MBL fold metallo-hydrolase | insig. | 24 | 33 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS06330 | | MBL fold metallo-hydrolase | insig. | 36 | 19 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_20400 | | Hydroxyacylglutathione hydrolase GloC | cofit | 27 | 32 |
| | Shewanella amazonensis SB2B | Sama_2142 | | metallo-beta-lactamase family protein (RefSeq) | sig. | 31 | 26 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3359 | | Zn-dependent hydrolases, including glyoxylases | insig. | 30 | 21 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS19750 | | MBL fold metallo-hydrolase | insig. | 28 | 29 |
| | Erwinia tracheiphila SCR3 | LU632_RS09895 | | MBL fold metallo-hydrolase | insig. | 27 | 32 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02085 | | Glyoxylase, beta-lactamase superfamily II | insig. | 33 | 19 |
| | Rhodospirillum rubrum S1H | Rru_A1522 | | Beta-lactamase-like (NCBI) | no data | 28 | 30 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS01930 | | hypothetical protein | insig. | 28 | 29 |
| | Alteromonas macleodii MIT1002 | MIT1002_03450 | | Beta-lactamase hydrolase-like protein | insig. | 27 | 29 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2691 | | Hydroxyacylglutathione hydrolase (RefSeq) | insig. | 30 | 26 |
| | Rhodopseudomonas palustris CGA009 | TX73_004405 | | MBL fold metallo-hydrolase | insig. | 31 | 21 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS01145 | | MBL fold metallo-hydrolase | insig. | 31 | 20 |