Conservation of cofitness between SMc00960 and SMc02370 in Sinorhizobium meliloti 1021

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc00960 hypothetical protein 1.0 SMc02370 aminopeptidase N 0.36 6
Rhizobium sp. OAE497 0.88 ABIE40_RS04050 metalloprotease TldD 0.75 ABIE40_RS05720 aminopeptidase N 0.88 32
Agrobacterium fabrum C58 0.88 Atu0765 TldD 0.71 Atu0984 aminopeptidase N low > 89
Azospirillum sp. SherDot2 0.62 MPMX19_00882 Metalloprotease TldD 0.44 MPMX19_04335 Aminopeptidase N low > 112
Azospirillum brasilense Sp245 0.62 AZOBR_RS10600 peptidase C69 0.45 AZOBR_RS14865 aminopeptidase N low > 97
Caulobacter crescentus NA1000 0.60 CCNA_03522 Zn-dependent protease TldD 0.42 CCNA_02566 membrane alanine aminopeptidase low > 66
Phaeobacter inhibens DSM 17395 0.60 PGA1_c06240 protein TldD 0.42 PGA1_c09880 aminopeptidase N 0.37 13
Caulobacter crescentus NA1000 Δfur 0.60 CCNA_03522 Zn-dependent protease TldD 0.42 CCNA_02566 membrane alanine aminopeptidase low > 67
Dinoroseobacter shibae DFL-12 0.59 Dshi_1139 peptidase U62 modulator of DNA gyrase (RefSeq) 0.44 Dshi_1223 aminopeptidase N (RefSeq) low > 64
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_2252 Predicted Zn-dependent proteases and their inactivated homologs 0.41 Ga0059261_2024 aminopeptidase N, Escherichia coli type 0.42 39
Alteromonas macleodii MIT1002 0.52 MIT1002_00227 protease TldD 0.37 MIT1002_02028 Aminopeptidase N low > 70
Pseudomonas putida KT2440 0.52 PP_0940 putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 0.45 PP_2017 aminopeptidase N low > 96
Hydrogenophaga sp. GW460-11-11-14-LB1 0.51 GFF580 TldD protein, part of TldE/TldD proteolytic complex 0.41 GFF275 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 90
Variovorax sp. OAS795 0.51 ABID97_RS06335 metalloprotease TldD 0.42 ABID97_RS21770 aminopeptidase N 0.75 7
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS01105 metalloprotease TldD 0.43 ABZR87_RS15120 aminopeptidase N 0.47 13
Variovorax sp. SCN45 0.51 GFF4449 TldD protein, part of TldE/TldD proteolytic complex 0.41 GFF3118 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 127
Acidovorax sp. GW101-3H11 0.51 Ac3H11_4036 TldD protein, part of TldE/TldD proteolytic complex 0.41 Ac3H11_2633 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 79
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.44 Psyr_1690 Peptidase M1, membrane alanine aminopeptidase low > 86
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.44 Psyr_1690 Peptidase M1, membrane alanine aminopeptidase low > 86
Ralstonia solanacearum PSI07 0.51 RPSI07_RS11850 metalloprotease TldD 0.43 RPSI07_RS14040 aminopeptidase N low > 81
Ralstonia solanacearum GMI1000 0.51 RS_RS13315 metalloprotease TldD 0.43 RS_RS10660 aminopeptidase N low > 80
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS21715 metalloprotease TldD 0.39 ABZR86_RS15770 aminopeptidase N low > 74
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS05875 protease TldD 0.43 RR42_RS05200 aminopeptidase N low > 128
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_05215 protease TldD 0.45 AO353_23630 aminopeptidase 0.39 9
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS05455 metalloprotease TldD 0.43 RALBFv3_RS03270 aminopeptidase N 0.77 7
Ralstonia solanacearum UW163 0.50 UW163_RS08170 metalloprotease TldD 0.43 UW163_RS10455 aminopeptidase N
Dechlorosoma suillum PS 0.50 Dsui_3401 putative Zn-dependent protease-like protein 0.42 Dsui_2287 aminopeptidase N low > 51
Pseudomonas fluorescens SBW25 0.50 PFLU_RS04340 metalloprotease TldD 0.45 PFLU_RS13095 aminopeptidase N low > 109
Pseudomonas fluorescens SBW25-INTG 0.50 PFLU_RS04340 metalloprotease TldD 0.45 PFLU_RS13095 aminopeptidase N 0.30 100
Pseudomonas simiae WCS417 0.50 PS417_04285 protease TldD 0.45 PS417_12395 aminopeptidase N low > 88
Pseudomonas fluorescens FW300-N2E2 0.50 Pf6N2E2_3280 TldD protein, part of TldE/TldD proteolytic complex 0.44 Pf6N2E2_604 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 103
Pseudomonas fluorescens FW300-N1B4 0.50 Pf1N1B4_1092 TldD protein, part of TldE/TldD proteolytic complex 0.44 Pf1N1B4_4614 Membrane alanine aminopeptidase N (EC 3.4.11.2) 0.31 23
Pseudomonas fluorescens GW456-L13 0.50 PfGW456L13_5026 TldD protein, part of TldE/TldD proteolytic complex 0.44 PfGW456L13_3325 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 87
Pseudomonas fluorescens FW300-N2C3 0.50 AO356_07095 protease TldD 0.44 AO356_24560 aminopeptidase 0.33 32
Pantoea sp. MT58 0.50 IAI47_02465 metalloprotease TldD 0.42 IAI47_12745 aminopeptidase N 0.40 46
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_02220 metalloprotease TldD 0.41 CSW01_07505 aminopeptidase N low > 62
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_10280 tldD metalloprotease TldD 0.39 OKGIIK_13715 Aminopeptidase N low > 52
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS03395 metalloprotease TldD 0.39 LRK54_RS10200 aminopeptidase N low > 59
Rhodanobacter denitrificans MT42 0.49 LRK55_RS03145 metalloprotease TldD 0.39 LRK55_RS09840 aminopeptidase N low > 63
Kangiella aquimarina DSM 16071 0.49 B158DRAFT_2072 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.43 B158DRAFT_1479 aminopeptidase N, Escherichia coli type low > 40
Pseudomonas stutzeri RCH2 0.49 Psest_3320 Predicted Zn-dependent proteases and their inactivated homologs 0.45 Psest_1922 aminopeptidase N, Escherichia coli type 0.22 27
Pseudomonas sp. RS175 0.49 PFR28_00161 Metalloprotease TldD 0.44 PFR28_01574 Aminopeptidase N low > 88
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS03540 peptidase C69 0.43 BPHYT_RS15210 aminopeptidase N low > 109
Dickeya dadantii 3937 0.49 DDA3937_RS01460 metalloprotease TldD 0.43 DDA3937_RS12885 aminopeptidase N low > 74
Castellaniella sp019104865 MT123 0.49 ABCV34_RS02590 metalloprotease TldD 0.39 ABCV34_RS02570 aminopeptidase N low > 48
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS26555 metalloprotease TldD 0.41 QEN71_RS03785 aminopeptidase N 0.81 102
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS07155 peptidase C69 0.44 HSERO_RS17720 aminopeptidase N 0.35 7
Dickeya dianthicola 67-19 0.49 HGI48_RS01380 metalloprotease TldD 0.42 HGI48_RS12955 aminopeptidase N low > 71
Escherichia coli BW25113 0.48 b3244 tldD predicted peptidase (NCBI) 0.41 b0932 pepN aminopeptidase N (NCBI) 0.28 12
Escherichia fergusonii Becca 0.48 EFB2_00586 Metalloprotease TldD 0.41 EFB2_03132 Aminopeptidase N low > 86
Escherichia coli ECOR38 0.48 HEPCGN_16620 tldD metalloprotease TldD 0.42 HEPCGN_23160 pepN aminopeptidase N low > 85
Escherichia coli BL21 0.48 ECD_03104 putative peptidase 0.41 ECD_00936 aminopeptidase N low > 60
Escherichia coli Nissle 1917 0.48 ECOLIN_RS18595 metalloprotease TldD 0.41 ECOLIN_RS04935 aminopeptidase N 0.55 2
Escherichia coli ECRC62 0.48 BNILDI_01980 tldD metalloprotease TldD 0.41 BNILDI_20175 pepN aminopeptidase N
Serratia liquefaciens MT49 0.48 IAI46_22685 metalloprotease TldD 0.43 IAI46_08775 aminopeptidase N low > 86
Escherichia coli ECOR27 0.48 NOLOHH_09555 tldD metalloprotease TldD 0.41 NOLOHH_21920 pepN aminopeptidase N low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_00460 Metalloprotease TldD 0.41 OHPLBJKB_02734 Aminopeptidase N low > 73
Escherichia coli ECRC102 0.48 NIAGMN_15515 tldD metalloprotease TldD 0.41 NIAGMN_03085 pepN aminopeptidase N
Escherichia coli ECRC101 0.48 MCAODC_08275 tldD metalloprotease TldD 0.41 MCAODC_24755 pepN aminopeptidase N
Escherichia coli ECRC101 0.48 OKFHMN_17755 tldD metalloprotease TldD 0.41 OKFHMN_05365 pepN aminopeptidase N
Escherichia coli ECRC99 0.48 KEDOAH_10395 tldD metalloprotease TldD 0.41 KEDOAH_22370 pepN aminopeptidase N
Dickeya dianthicola ME23 0.48 DZA65_RS01440 metalloprotease TldD 0.42 DZA65_RS13420 aminopeptidase N low > 75
Escherichia coli ECRC98 0.48 JDDGAC_21380 tldD metalloprotease TldD 0.41 JDDGAC_08975 pepN aminopeptidase N
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF2140 TldD protein, part of TldE/TldD proteolytic complex 0.42 GFF3235 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 78
Shewanella sp. ANA-3 0.48 Shewana3_3641 microcin-processing peptidase 2 (RefSeq) 0.40 Shewana3_1779 pepN aminopeptidase N (RefSeq) low > 73
Pseudomonas sp. S08-1 0.48 OH686_08580 TldD protein, part of TldE/TldD proteolytic complex 0.44 OH686_04270 aminopeptidase N low > 80
Enterobacter sp. TBS_079 0.48 MPMX20_04151 Metalloprotease TldD 0.41 MPMX20_01590 Aminopeptidase N low > 85
Klebsiella michiganensis M5al 0.48 BWI76_RS25470 metalloprotease TldD 0.41 BWI76_RS09890 aminopeptidase N low > 92
Paraburkholderia bryophila 376MFSha3.1 0.48 H281DRAFT_04688 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.43 H281DRAFT_03988 alanyl aminopeptidase. Metallo peptidase. MEROPS family M01 low > 103
Paraburkholderia graminis OAS925 0.48 ABIE53_000851 TldD protein 0.42 ABIE53_003216 aminopeptidase N 0.56 2
Pectobacterium carotovorum WPP14 0.48 HER17_RS20140 metalloprotease TldD 0.43 HER17_RS12010 aminopeptidase N low > 75
Enterobacter asburiae PDN3 0.47 EX28DRAFT_3295 Predicted Zn-dependent proteases and their inactivated homologs 0.41 EX28DRAFT_2004 aminopeptidase N, Escherichia coli type low > 76
Shewanella loihica PV-4 0.47 Shew_0410 peptidase U62, modulator of DNA gyrase (RefSeq) 0.43 Shew_1803 aminopeptidase N (RefSeq) low > 60
Erwinia tracheiphila SCR3 0.47 LU632_RS21420 tldD metalloprotease TldD 0.41 LU632_RS09930 pepN aminopeptidase N low > 74
Rahnella sp. WP5 0.47 EX31_RS12265 metalloprotease TldD 0.43 EX31_RS18125 aminopeptidase N low > 89
Shewanella amazonensis SB2B 0.46 Sama_0474 TldD protein (RefSeq) 0.38 Sama_1586 pepN aminopeptidase N (RefSeq) low > 62
Shewanella oneidensis MR-1 0.46 SO4091 tldD tldD protein (NCBI ptt file) 0.40 SO2600 pepN aminopeptidase N (NCBI ptt file) low > 76

Not shown: 11 genomes with orthologs for SMc00960 only; 2 genomes with orthologs for SMc02370 only