Conservation of cofitness between PFLU_RS04350 and PFLU_RS13095 in Pseudomonas fluorescens SBW25

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens SBW25 1.0 PFLU_RS04350 metalloprotease PmbA 1.0 PFLU_RS13095 aminopeptidase N 0.67 9
Pseudomonas fluorescens SBW25-INTG 1.00 PFLU_RS04350 metalloprotease PmbA 1.00 PFLU_RS13095 aminopeptidase N 0.34 36
Pseudomonas simiae WCS417 0.98 PS417_04295 peptidase PmbA 0.97 PS417_12395 aminopeptidase N low > 88
Pseudomonas fluorescens FW300-N2C3 0.96 AO356_07085 peptidase PmbA 0.92 AO356_24560 aminopeptidase 0.40 7
Pseudomonas fluorescens FW300-N2E2 0.95 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.91 Pf6N2E2_604 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 103
Pseudomonas sp. RS175 0.95 PFR28_00163 Metalloprotease PmbA 0.91 PFR28_01574 Aminopeptidase N low > 88
Pseudomonas fluorescens FW300-N2E3 0.93 AO353_05205 peptidase PmbA 0.91 AO353_23630 aminopeptidase 0.33 39
Pseudomonas fluorescens GW456-L13 0.93 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex 0.93 PfGW456L13_3325 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 87
Pseudomonas fluorescens FW300-N1B4 0.93 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.93 Pf1N1B4_4614 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 87
Pseudomonas putida KT2440 0.90 PP_0942 regulatory protease 0.86 PP_2017 aminopeptidase N 0.14 60
Pseudomonas syringae pv. syringae B728a ΔmexB 0.89 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.88 Psyr_1690 Peptidase M1, membrane alanine aminopeptidase low > 86
Pseudomonas syringae pv. syringae B728a 0.89 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.88 Psyr_1690 Peptidase M1, membrane alanine aminopeptidase low > 86
Pseudomonas sp. S08-1 0.81 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.84 OH686_04270 aminopeptidase N low > 80
Pseudomonas stutzeri RCH2 0.77 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.84 Psest_1922 aminopeptidase N, Escherichia coli type low > 67
Shewanella sp. ANA-3 0.51 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.44 Shewana3_1779 pepN aminopeptidase N (RefSeq) low > 73
Shewanella amazonensis SB2B 0.50 Sama_0482 PmbA protein (RefSeq) 0.40 Sama_1586 pepN aminopeptidase N (RefSeq) low > 62
Shewanella oneidensis MR-1 0.50 SO4078 pmbA pmba protein (NCBI ptt file) 0.43 SO2600 pepN aminopeptidase N (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.50 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.45 Shew_1803 aminopeptidase N (RefSeq) low > 60
Pectobacterium carotovorum WPP14 0.50 HER17_RS20090 metalloprotease PmbA 0.48 HER17_RS12010 aminopeptidase N low > 75
Rahnella sp. WP5 0.49 EX31_RS12320 metalloprotease PmbA 0.48 EX31_RS18125 aminopeptidase N low > 89
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_10260 pmbA metalloprotease PmbA 0.41 OKGIIK_13715 Aminopeptidase N low > 52
Escherichia fergusonii Becca 0.48 EFB2_04298 Metalloprotease PmbA 0.48 EFB2_03132 Aminopeptidase N low > 86
Enterobacter sp. TBS_079 0.48 MPMX20_00517 Metalloprotease PmbA 0.47 MPMX20_01590 Aminopeptidase N low > 85
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.47 EX28DRAFT_2004 aminopeptidase N, Escherichia coli type low > 76
Escherichia coli BW25113 0.48 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 0.48 b0932 pepN aminopeptidase N (NCBI) 0.22 59
Escherichia coli ECRC99 0.48 KEDOAH_16230 pmbA metalloprotease PmbA 0.48 KEDOAH_22370 pepN aminopeptidase N
Escherichia coli ECOR38 0.48 HEPCGN_10125 pmbA metalloprotease PmbA 0.48 HEPCGN_23160 pepN aminopeptidase N low > 87
Escherichia coli ECRC102 0.48 NIAGMN_09775 pmbA metalloprotease PmbA 0.48 NIAGMN_03085 pepN aminopeptidase N
Escherichia coli ECRC98 0.48 JDDGAC_15565 pmbA metalloprotease PmbA 0.48 JDDGAC_08975 pepN aminopeptidase N low > 86
Escherichia coli BL21 0.48 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 0.48 ECD_00936 aminopeptidase N low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_03800 Metalloprotease PmbA 0.48 OHPLBJKB_02734 Aminopeptidase N 0.45 43
Rhodanobacter denitrificans MT42 0.48 LRK55_RS03125 metalloprotease PmbA 0.41 LRK55_RS09840 aminopeptidase N low > 63
Escherichia coli ECRC62 0.48 BNILDI_07325 pmbA metalloprotease PmbA 0.48 BNILDI_20175 pepN aminopeptidase N low > 75
Escherichia coli Nissle 1917 0.48 ECOLIN_RS24570 metalloprotease PmbA 0.48 ECOLIN_RS04935 aminopeptidase N low > 55
Escherichia coli ECRC101 0.48 MCAODC_02430 pmbA metalloprotease PmbA 0.48 MCAODC_24755 pepN aminopeptidase N low > 87
Dechlorosoma suillum PS 0.48 Dsui_1234 putative Zn-dependent protease-like protein 0.48 Dsui_2287 aminopeptidase N low > 51
Escherichia coli ECRC100 0.48 OKFHMN_11925 pmbA metalloprotease PmbA 0.48 OKFHMN_05365 pepN aminopeptidase N low > 80
Escherichia coli ECOR27 0.48 NOLOHH_04185 pmbA metalloprotease PmbA 0.48 NOLOHH_21920 pepN aminopeptidase N low > 75
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS03375 metalloprotease PmbA 0.41 LRK54_RS10200 aminopeptidase N low > 59
Klebsiella michiganensis M5al 0.48 BWI76_RS02850 metalloprotease PmbA 0.46 BWI76_RS09890 aminopeptidase N 0.20 12
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_12845 metalloprotease PmbA 0.47 CSW01_07505 aminopeptidase N low > 62
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.47 GFF3235 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 78
Alteromonas macleodii MIT1002 0.48 MIT1002_00230 peptidase PmbA 0.40 MIT1002_02028 Aminopeptidase N low > 70
Serratia liquefaciens MT49 0.48 IAI46_22575 metalloprotease PmbA 0.49 IAI46_08775 aminopeptidase N low > 86
Dyella japonica UNC79MFTsu3.2 0.47 ABZR86_RS21700 metalloprotease PmbA 0.41 ABZR86_RS15770 aminopeptidase N low > 74
Erwinia tracheiphila SCR3 0.47 LU632_RS02145 pmbA metalloprotease PmbA 0.46 LU632_RS09930 pepN aminopeptidase N low > 74
Dickeya dadantii 3937 0.47 DDA3937_RS01500 metalloprotease PmbA 0.48 DDA3937_RS12885 aminopeptidase N low > 74
Dickeya dianthicola ME23 0.47 DZA65_RS01480 metalloprotease PmbA 0.48 DZA65_RS13420 aminopeptidase N low > 75
Dickeya dianthicola 67-19 0.47 HGI48_RS01415 metalloprotease PmbA 0.48 HGI48_RS12955 aminopeptidase N low > 71
Pantoea sp. MT58 0.46 IAI47_02765 metalloprotease PmbA 0.47 IAI47_12745 aminopeptidase N 0.32 71
Variovorax sp. SCN45 0.46 GFF4697 TldE protein, part of TldE/TldD proteolytic complex 0.44 GFF3118 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 127
Herbaspirillum seropedicae SmR1 0.45 HSERO_RS09265 peptidase C69 0.50 HSERO_RS17720 aminopeptidase N 0.29 49
Variovorax sp. OAS795 0.45 ABID97_RS20695 metalloprotease PmbA 0.43 ABID97_RS21770 aminopeptidase N 0.77 3
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS13965 metalloprotease PmbA 0.48 RALBFv3_RS03270 aminopeptidase N 0.72 13
Ralstonia solanacearum UW163 0.44 UW163_RS15845 metalloprotease PmbA 0.48 UW163_RS10455 aminopeptidase N
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS04270 metalloprotease PmbA 0.46 QEN71_RS03785 aminopeptidase N 0.72 135
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_04304 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.46 H281DRAFT_03988 alanyl aminopeptidase. Metallo peptidase. MEROPS family M01 low > 103
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS09660 metalloprotease PmbA 0.47 ABZR87_RS15120 aminopeptidase N 0.42 21
Paraburkholderia graminis OAS925 0.44 ABIE53_003116 PmbA protein 0.46 ABIE53_003216 aminopeptidase N 0.57 3
Cupriavidus basilensis FW507-4G11 0.44 RR42_RS14750 peptidase PMbA 0.49 RR42_RS05200 aminopeptidase N low > 128
Ralstonia solanacearum PSI07 0.43 RPSI07_RS19505 metalloprotease PmbA 0.48 RPSI07_RS14040 aminopeptidase N low > 81
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS14705 peptidase C69 0.47 BPHYT_RS15210 aminopeptidase N low > 109
Acidovorax sp. GW101-3H11 0.43 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex 0.44 Ac3H11_2633 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 79
Castellaniella sp019104865 MT123 0.42 ABCV34_RS10610 metalloprotease PmbA 0.38 ABCV34_RS02570 aminopeptidase N low > 48
Ralstonia solanacearum GMI1000 0.42 RS_RS04700 metalloprotease PmbA 0.47 RS_RS10660 aminopeptidase N low > 80
Hydrogenophaga sp. GW460-11-11-14-LB1 0.40 GFF3655 TldE protein, part of TldE/TldD proteolytic complex 0.42 GFF275 Membrane alanine aminopeptidase N (EC 3.4.11.2) low > 90
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.50 B158DRAFT_1479 aminopeptidase N, Escherichia coli type low > 40
Azospirillum brasilense Sp245 0.29 AZOBR_RS11930 modulator protein 0.56 AZOBR_RS14865 aminopeptidase N 0.27 75
Azospirillum sp. SherDot2 0.28 MPMX19_01886 Metalloprotease PmbA 0.54 MPMX19_04335 Aminopeptidase N low > 112
Dinoroseobacter shibae DFL-12 0.27 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) 0.42 Dshi_1223 aminopeptidase N (RefSeq) low > 64
Sphingomonas koreensis DSMZ 15582 0.26 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs 0.42 Ga0059261_2024 aminopeptidase N, Escherichia coli type low > 68
Phaeobacter inhibens DSM 17395 0.26 PGA1_c33480 protein PmbA 0.41 PGA1_c09880 aminopeptidase N
Sinorhizobium meliloti 1021 0.25 SMc00897 PMBA protein 0.43 SMc02370 aminopeptidase N 0.34 5
Agrobacterium fabrum C58 0.25 Atu0693 PmbA/TldD related protein 0.42 Atu0984 aminopeptidase N low > 89
Rhizobium sp. OAE497 0.24 ABIE40_RS03780 TldD/PmbA family protein 0.43 ABIE40_RS05720 aminopeptidase N 0.88 29
Caulobacter crescentus NA1000 0.24 CCNA_00311 Zn-dependent protease family protein 0.41 CCNA_02566 membrane alanine aminopeptidase low > 66
Caulobacter crescentus NA1000 Δfur 0.24 CCNA_00311 Zn-dependent protease family protein 0.41 CCNA_02566 membrane alanine aminopeptidase low > 67

Not shown: 10 genomes with orthologs for PFLU_RS04350 only; 2 genomes with orthologs for PFLU_RS13095 only