Conservation of cofitness between GFF2057 and GFF3455 in Sphingobium sp. HT1-2

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF2057 Ketol-acid reductoisomerase (NADP(+)) (EC 1.1.1.86) 1.0 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.93 3
Sphingomonas koreensis DSMZ 15582 0.91 Ga0059261_0066 ketol-acid reductoisomerase (EC 1.1.1.86) 0.80 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) — —
Caulobacter crescentus NA1000 0.78 CCNA_02204 ketol-acid reductoisomerase/2-dehydropantoate 2-reductase 0.50 CCNA_02321 O-succinylhomoserine sulfhydrylase — —
Caulobacter crescentus NA1000 Δfur 0.78 CCNA_02204 ketol-acid reductoisomerase/2-dehydropantoate 2-reductase 0.50 CCNA_02321 O-succinylhomoserine sulfhydrylase — —
Azospirillum brasilense Sp245 0.78 AZOBR_RS06570 ketol-acid reductoisomerase 0.45 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase — —
Azospirillum sp. SherDot2 0.77 MPMX19_01774 Ketol-acid reductoisomerase (NADP(+)) 0.47 MPMX19_01364 O-succinylhomoserine sulfhydrylase — —
Rhodospirillum rubrum S1H 0.77 Rru_A0469 Ketol-acid reductoisomerase (NCBI) 0.50 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) 0.88 21
Magnetospirillum magneticum AMB-1 0.76 AMB_RS17750 ketol-acid reductoisomerase 0.56 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Sinorhizobium meliloti 1021 0.75 SMc04346 ketol-acid reductoisomerase 0.54 SMc02217 O-succinylhomoserine sulfhydrylase 0.91 21
Rhodopseudomonas palustris CGA009 0.75 TX73_010485 ketol-acid reductoisomerase 0.50 TX73_024775 O-succinylhomoserine sulfhydrylase — —
Rhizobium sp. OAE497 0.74 ABIE40_RS11360 ketol-acid reductoisomerase 0.53 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase — —
Agrobacterium fabrum C58 0.73 Atu2019 ketol-acid reductoisomerase 0.53 Atu0432 O-succinylhomoserine sulfhydrylase — —
Xanthobacter sp. DMC5 0.73 GFF172 Ketol-acid reductoisomerase (NADP(+)) 0.51 GFF4634 O-succinylhomoserine sulfhydrylase — —
Phaeobacter inhibens DSM 17395 0.71 PGA1_c06580 ketol-acid reductoisomerase IlvC 0.48 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ — —
Dinoroseobacter shibae DFL-12 0.70 Dshi_2396 ketol-acid reductoisomerase (RefSeq) 0.47 Dshi_2410 O-succinylhomoserine sulfhydrylase (RefSeq) — —
Castellaniella sp019104865 MT123 0.69 ABCV34_RS01220 ketol-acid reductoisomerase 0.31 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 48
Ralstonia solanacearum PSI07 0.68 RPSI07_RS14265 ketol-acid reductoisomerase 0.31 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase — —
Cupriavidus basilensis FW507-4G11 0.68 RR42_RS05445 ketol-acid reductoisomerase 0.44 RR42_RS14320 O-succinylhomoserine sulfhydrylase — —
Variovorax sp. SCN45 0.67 GFF1161 Ketol-acid reductoisomerase (NADP(+)) (EC 1.1.1.86) 0.42 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Variovorax sp. OAS795 0.67 ABID97_RS14895 ketol-acid reductoisomerase 0.42 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Ralstonia sp. UNC404CL21Col 0.67 ABZR87_RS14945 ketol-acid reductoisomerase 0.33 ABZR87_RS13810 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum IBSBF1503 0.67 RALBFv3_RS03040 ketol-acid reductoisomerase 0.31 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum UW163 0.67 UW163_RS10685 ketol-acid reductoisomerase 0.31 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum GMI1000 0.67 RS_RS10410 ketol-acid reductoisomerase 0.31 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase — —
Herbaspirillum seropedicae SmR1 0.66 HSERO_RS08660 ketol-acid reductoisomerase 0.29 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase low > 78
Paraburkholderia sabiae LMG 24235 0.66 QEN71_RS24215 ketol-acid reductoisomerase 0.46 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Methylophilus sp. DMC18 0.66 GFF2519 Ketol-acid reductoisomerase (NADP(+)) 0.41 GFF662 O-succinylhomoserine sulfhydrylase — —
Paraburkholderia bryophila 376MFSha3.1 0.66 H281DRAFT_04553 ketol-acid reductoisomerase 0.46 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase 0.58 10
Dechlorosoma suillum PS 0.66 Dsui_3527 ketol-acid reductoisomerase 0.45 Dsui_3185 O-succinylhomoserine sulfhydrylase — —
Burkholderia phytofirmans PsJN 0.66 BPHYT_RS06555 ketol-acid reductoisomerase 0.47 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.95 3
Paraburkholderia graminis OAS925 0.65 ABIE53_001576 ketol-acid reductoisomerase 0.47 ABIE53_004817 O-succinylhomoserine sulfhydrylase — —
Acinetobacter baumannii LAC-4 0.65 RR41_RS16325 ketol-acid reductoisomerase 0.42 RR41_RS12630 O-succinylhomoserine sulfhydrylase low > 55
Acinetobacter radioresistens SK82 0.65 MPMX26_00474 Ketol-acid reductoisomerase (NADP(+)) 0.42 MPMX26_01645 O-succinylhomoserine sulfhydrylase 0.91 19
Pseudomonas aeruginosa PA14 0.64 IKLFDK_30155 ketol-acid reductoisomerase 0.40 IKLFDK_15810 O-succinylhomoserine sulfhydrylase low > 100
Pseudomonas fluorescens SBW25 0.64 PFLU_RS25640 ketol-acid reductoisomerase 0.41 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.79 11
Pseudomonas fluorescens SBW25-INTG 0.64 PFLU_RS25640 ketol-acid reductoisomerase 0.41 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.79 8
Pseudomonas segetis P6 0.64 MPMX49_01277 Ketol-acid reductoisomerase (NADP(+)) 0.39 MPMX49_03060 O-succinylhomoserine sulfhydrylase 0.89 3
Pseudomonas lactucae CFBP13502 0.64 GEMAOFIL_04911 Ketol-acid reductoisomerase (NADP(+)) 0.40 GEMAOFIL_03934 O-succinylhomoserine sulfhydrylase 0.52 89
Pseudomonas fluorescens FW300-N2E3 0.63 AO353_14505 ketol-acid reductoisomerase 0.40 AO353_20695 O-succinylhomoserine sulfhydrylase 0.96 7
Pseudomonas simiae WCS417 0.63 PS417_23800 ketol-acid reductoisomerase 0.40 PS417_18530 O-succinylhomoserine sulfhydrylase 0.96 4
Synechococcus elongatus PCC 7942 0.63 Synpcc7942_1552 ilvC ketol-acid reductoisomerase 0.26 Synpcc7942_0370 metY O-acetylhomoserine/O-acetylserine sulfhydrylase — —
Pseudomonas fluorescens FW300-N2C3 0.63 AO356_16180 ketol-acid reductoisomerase 0.40 AO356_21470 O-succinylhomoserine sulfhydrylase 0.98 5
Pseudomonas syringae pv. syringae B728a ΔmexB 0.63 Psyr_0848 ketol-acid reductoisomerase 0.43 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.92 9
Pseudomonas syringae pv. syringae B728a 0.63 Psyr_0848 ketol-acid reductoisomerase 0.43 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.94 5
Pseudomonas sp. DMC3 0.63 GFF4052 Ketol-acid reductoisomerase (NADP(+)) 0.41 GFF799 O-succinylhomoserine sulfhydrylase 0.99 3
Pseudomonas stutzeri RCH2 0.63 Psest_1038 ketol-acid reductoisomerase 0.39 Psest_2578 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens GW456-L13 0.63 PfGW456L13_1540 Ketol-acid reductoisomerase (EC 1.1.1.86) 0.40 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.96 6
Pseudomonas sp. BP01 0.63 JOY50_RS27770 ilvC ketol-acid reductoisomerase 0.40 JOY50_RS16560 O-succinylhomoserine sulfhydrylase 0.96 22
Pseudomonas sp. S08-1 0.63 OH686_08115 ketol-acid reductoisomerase 0.41 OH686_04415 O-succinylhomoserine sulfhydrylase 0.71 34
Pseudomonas putida KT2440 0.63 PP_4678 Ketol-acid reductoisomerase 0.39 PP_2001 O-succinylhomoserine sulfhydrylase 0.91 16
Pseudomonas sp. SVBP6 0.62 COO64_RS14995 ilvC ketol-acid reductoisomerase 0.40 COO64_RS05595 O-succinylhomoserine sulfhydrylase 0.99 10
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5177 Ketol-acid reductoisomerase (EC 1.1.1.86) 0.40 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.94 7
Hydrogenophaga sp. GW460-11-11-14-LB1 0.62 GFF4278 Ketol-acid reductoisomerase (EC 1.1.1.86) 0.46 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Pseudomonas sp. RS175 0.62 PFR28_03697 Ketol-acid reductoisomerase (NADP(+)) 0.40 PFR28_02810 O-succinylhomoserine sulfhydrylase 0.62 26
Acidovorax sp. GW101-3H11 0.62 Ac3H11_527 Ketol-acid reductoisomerase (EC 1.1.1.86) 0.32 Ac3H11_2928 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Marinobacter adhaerens HP15 0.59 HP15_533 ketol-acid reductoisomerase 0.36 HP15_1820 methionine gamma-lyase — —
Mycobacterium tuberculosis H37Rv 0.55 Rv3001c Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) (alpha-keto-beta-hydroxylacil reductoisomerase) 0.44 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) — —
Rhodanobacter sp000427505 FW510-R12 0.53 LRK53_RS03090 ketol-acid reductoisomerase 0.28 LRK53_RS04370 cystathionine gamma-synthase low > 59
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS10315 ketol-acid reductoisomerase 0.27 LRK54_RS05660 PLP-dependent aspartate aminotransferase family protein low > 59
Rhodanobacter denitrificans MT42 0.53 LRK55_RS09955 ketol-acid reductoisomerase 0.28 LRK55_RS05410 cystathionine gamma-synthase low > 63
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_13605 ilvC ketol-acid reductoisomerase 0.28 OKGIIK_01180 metC cystathionine beta-lyase low > 53
Xanthomonas campestris pv. campestris strain 8004 0.52 Xcc-8004.1060.1 Ketol-acid reductoisomerase (EC 1.1.1.86) 0.31 Xcc-8004.1385.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 74
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS15940 ketol-acid reductoisomerase 0.29 ABZR86_RS18745 PLP-dependent aspartate aminotransferase family protein — —
Brevundimonas sp. GW460-12-10-14-LB2 0.49 A4249_RS05080 ketol-acid reductoisomerase 0.29 A4249_RS08315 cystathionine gamma-synthase — —
Bifidobacterium breve UCC2003 0.49 BBR_RS10830 ketol-acid reductoisomerase 0.30 BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 34
Lysobacter sp. OAE881 0.49 ABIE51_RS17545 ketol-acid reductoisomerase 0.30 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Pontibacter actiniarum KMM 6156, DSM 19842 0.22 CA264_06920 ketol-acid reductoisomerase 0.40 CA264_02530 O-succinylhomoserine sulfhydrylase low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_2058 ketol-acid reductoisomerase 0.41 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases 0.93 14
Bacteroides stercoris CC31F 0.19 HMPREF1181_RS08315 ketol-acid reductoisomerase 0.35 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 56
Bacteroides ovatus ATCC 8483 0.19 BACOVA_03306 ketol-acid reductoisomerase 0.36 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 96
Bacteroides thetaiotaomicron VPI-5482 0.19 BT2074 ketol-acid reductoisomerase (NCBI ptt file) 0.36 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) low > 81

Not shown: 7 genomes with orthologs for GFF2057 only; 41 genomes with orthologs for GFF3455 only