Conservation of cofitness between GFF4449 and GFF2572 in Variovorax sp. SCN45

75 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Variovorax sp. SCN45 1.0 GFF4449 TldD protein, part of TldE/TldD proteolytic complex 1.0 GFF2572 Protein-export protein SecB (maintains pre-export unfolded state) 0.90 20
Variovorax sp. OAS795 0.95 ABID97_RS06335 metalloprotease TldD 0.87 ABID97_RS07400 protein-export chaperone SecB low > 91
Acidovorax sp. GW101-3H11 0.86 Ac3H11_4036 TldD protein, part of TldE/TldD proteolytic complex 0.77 Ac3H11_3859 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) 0.35 42
Hydrogenophaga sp. GW460-11-11-14-LB1 0.85 GFF580 TldD protein, part of TldE/TldD proteolytic complex 0.78 GFF1223 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) low > 90
Herbaspirillum seropedicae SmR1 0.73 HSERO_RS07155 peptidase C69 0.65 HSERO_RS00805 preprotein translocase subunit SecB low > 78
Cupriavidus basilensis FW507-4G11 0.73 RR42_RS05875 protease TldD 0.56 RR42_RS01840 preprotein translocase subunit SecB
Ralstonia sp. UNC404CL21Col 0.72 ABZR87_RS01105 metalloprotease TldD 0.65 ABZR87_RS06765 protein-export chaperone SecB
Ralstonia solanacearum GMI1000 0.72 RS_RS13315 metalloprotease TldD 0.65 RS_RS01755 protein-export protein SecB low > 80
Burkholderia phytofirmans PsJN 0.72 BPHYT_RS03540 peptidase C69 0.65 BPHYT_RS02605 protein-export protein SecB
Ralstonia solanacearum IBSBF1503 0.72 RALBFv3_RS05455 metalloprotease TldD 0.65 RALBFv3_RS10915 protein-export chaperone SecB
Ralstonia solanacearum UW163 0.72 UW163_RS08170 metalloprotease TldD 0.65 UW163_RS02665 protein-export chaperone SecB
Ralstonia solanacearum PSI07 0.71 RPSI07_RS11850 metalloprotease TldD 0.66 RPSI07_RS22395 protein-export chaperone SecB low > 81
Paraburkholderia sabiae LMG 24235 0.71 QEN71_RS26555 metalloprotease TldD 0.65 QEN71_RS01460 protein-export chaperone SecB low > 153
Paraburkholderia bryophila 376MFSha3.1 0.71 H281DRAFT_04688 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.65 H281DRAFT_02001 protein translocase subunit secB low > 103
Paraburkholderia graminis OAS925 0.71 ABIE53_000851 TldD protein 0.63 ABIE53_000666 preprotein translocase subunit SecB low > 113
Castellaniella sp019104865 MT123 0.70 ABCV34_RS02590 metalloprotease TldD 0.57 ABCV34_RS14255 protein-export chaperone SecB low > 48
Dechlorosoma suillum PS 0.67 Dsui_3401 putative Zn-dependent protease-like protein 0.50 Dsui_1275 protein-export chaperone SecB low > 51
Dyella japonica UNC79MFTsu3.2 0.62 ABZR86_RS21715 metalloprotease TldD 0.38 ABZR86_RS13255 protein-export chaperone SecB
Rhodanobacter sp. FW510-T8 0.61 OKGIIK_10280 tldD metalloprotease TldD 0.37 OKGIIK_13020 secB protein-export chaperone SecB
Rhodanobacter denitrificans MT42 0.59 LRK55_RS03145 metalloprotease TldD 0.37 LRK55_RS10545 protein-export chaperone SecB
Alteromonas macleodii MIT1002 0.59 MIT1002_00227 protease TldD 0.42 MIT1002_00486 Protein-export protein SecB low > 70
Rhodanobacter denitrificans FW104-10B01 0.59 LRK54_RS03395 metalloprotease TldD 0.37 LRK54_RS10855 protein-export chaperone SecB low > 59
Shewanella sp. ANA-3 0.58 Shewana3_3641 microcin-processing peptidase 2 (RefSeq) 0.40 Shewana3_0053 preprotein translocase subunit SecB (RefSeq)
Pseudomonas putida KT2440 0.58 PP_0940 putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 0.36 PP_5053 Protein-export protein SecB low > 96
Lysobacter sp. OAE881 0.58 ABIE51_RS06795 metalloprotease TldD 0.40 ABIE51_RS00490 protein-export chaperone SecB low > 62
Pantoea sp. MT58 0.58 IAI47_02465 metalloprotease TldD 0.38 IAI47_00735 protein-export chaperone SecB low > 76
Pseudomonas syringae pv. syringae B728a ΔmexB 0.58 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.38 Psyr_4882 protein translocase subunit secB low > 86
Pseudomonas syringae pv. syringae B728a 0.58 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.38 Psyr_4882 protein translocase subunit secB low > 86
Shewanella oneidensis MR-1 0.57 SO4091 tldD tldD protein (NCBI ptt file) 0.39 SO0052 secB protein-export protein SecB (NCBI ptt file)
Shewanella loihica PV-4 0.56 Shew_0410 peptidase U62, modulator of DNA gyrase (RefSeq) 0.40 Shew_3804 preprotein translocase subunit SecB (RefSeq)
Serratia liquefaciens MT49 0.56 IAI46_22685 metalloprotease TldD 0.39 IAI46_24695 protein-export chaperone SecB low > 86
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_05215 protease TldD 0.38 AO353_12130 preprotein translocase subunit SecB low > 101
Pseudomonas fluorescens SBW25 0.56 PFLU_RS04340 metalloprotease TldD 0.37 PFLU_RS01670 protein-export chaperone SecB low > 109
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS04340 metalloprotease TldD 0.37 PFLU_RS01670 protein-export chaperone SecB low > 109
Pseudomonas simiae WCS417 0.56 PS417_04285 protease TldD 0.37 PS417_01620 preprotein translocase subunit SecB low > 88
Pseudomonas stutzeri RCH2 0.56 Psest_3320 Predicted Zn-dependent proteases and their inactivated homologs 0.37 Psest_0165 protein-export chaperone SecB low > 67
Dickeya dadantii 3937 0.56 DDA3937_RS01460 metalloprotease TldD 0.39 DDA3937_RS20410 protein-export chaperone SecB low > 74
Pseudomonas sp. RS175 0.56 PFR28_00161 Metalloprotease TldD 0.37 PFR28_04941 Protein-export protein SecB low > 88
Dickeya dianthicola 67-19 0.56 HGI48_RS01380 metalloprotease TldD 0.38 HGI48_RS00790 protein-export chaperone SecB low > 71
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_1092 TldD protein, part of TldE/TldD proteolytic complex 0.38 Pf1N1B4_1614 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) low > 87
Pseudomonas fluorescens FW300-N2C3 0.55 AO356_07095 protease TldD 0.38 AO356_09755 preprotein translocase subunit SecB low > 104
Pseudomonas sp. S08-1 0.55 OH686_08580 TldD protein, part of TldE/TldD proteolytic complex 0.34 OH686_14670 protein-export chaperone SecB low > 80
Dickeya dianthicola ME23 0.55 DZA65_RS01440 metalloprotease TldD 0.38 DZA65_RS00845 protein-export chaperone SecB low > 75
Enterobacter sp. TBS_079 0.55 MPMX20_04151 Metalloprotease TldD 0.39 MPMX20_00124 Protein-export protein SecB
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_3280 TldD protein, part of TldE/TldD proteolytic complex 0.37 Pf6N2E2_3829 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) 0.24 81
Pseudomonas fluorescens GW456-L13 0.55 PfGW456L13_5026 TldD protein, part of TldE/TldD proteolytic complex 0.39 PfGW456L13_350 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) low > 87
Klebsiella michiganensis M5al 0.55 BWI76_RS25470 metalloprotease TldD 0.41 BWI76_RS27215 protein-export protein SecB
Escherichia coli ECOR27 0.55 NOLOHH_09555 tldD metalloprotease TldD 0.39 NOLOHH_07630 secB protein-export chaperone SecB low > 75
Escherichia coli ECRC99 0.55 KEDOAH_10395 tldD metalloprotease TldD 0.39 KEDOAH_12400 secB protein-export chaperone SecB
Shewanella amazonensis SB2B 0.55 Sama_0474 TldD protein (RefSeq) 0.45 Sama_0062 preprotein translocase subunit SecB (RefSeq)
Escherichia coli ECRC101 0.55 MCAODC_08275 tldD metalloprotease TldD 0.39 MCAODC_06260 secB protein-export chaperone SecB
Escherichia fergusonii Becca 0.55 EFB2_00586 Metalloprotease TldD 0.39 EFB2_00201 Protein-export protein SecB
Escherichia coli BW25113 0.55 b3244 tldD predicted peptidase (NCBI) 0.39 b3609 secB export protein SecB (NCBI) low > 76
Escherichia coli ECRC102 0.55 NIAGMN_15515 tldD metalloprotease TldD 0.39 NIAGMN_13510 secB protein-export chaperone SecB
Escherichia coli Nissle 1917 0.55 ECOLIN_RS18595 metalloprotease TldD 0.39 ECOLIN_RS20600 protein-export chaperone SecB
Escherichia coli ECOR38 0.55 HEPCGN_16620 tldD metalloprotease TldD 0.39 HEPCGN_14590 secB protein-export chaperone SecB
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_00460 Metalloprotease TldD 0.39 OHPLBJKB_00090 Protein-export protein SecB
Escherichia coli ECRC98 0.55 JDDGAC_21380 tldD metalloprotease TldD 0.39 JDDGAC_19375 secB protein-export chaperone SecB
Escherichia coli ECRC62 0.55 BNILDI_01980 tldD metalloprotease TldD 0.39 BNILDI_03885 secB protein-export chaperone SecB
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_02220 metalloprotease TldD 0.36 CSW01_13410 protein-export protein SecB low > 62
Escherichia coli BL21 0.55 ECD_03104 putative peptidase 0.39 ECD_03467 protein export chaperone
Pectobacterium carotovorum WPP14 0.55 HER17_RS20140 metalloprotease TldD 0.39 HER17_RS20740 protein-export chaperone SecB low > 75
Escherichia coli ECRC100 0.55 OKFHMN_17755 tldD metalloprotease TldD 0.39 OKFHMN_15750 secB protein-export chaperone SecB
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF2140 TldD protein, part of TldE/TldD proteolytic complex 0.39 GFF401 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) low > 78
Enterobacter asburiae PDN3 0.54 EX28DRAFT_3295 Predicted Zn-dependent proteases and their inactivated homologs 0.39 EX28DRAFT_3860 protein-export chaperone SecB
Magnetospirillum magneticum AMB-1 0.54 AMB_RS21030 metalloprotease TldD 0.26 AMB_RS22995 protein-export protein SecB low > 64
Rahnella sp. WP5 0.54 EX31_RS12265 metalloprotease TldD 0.42 EX31_RS14345 protein-export chaperone SecB low > 89
Erwinia tracheiphila SCR3 0.54 LU632_RS21420 tldD metalloprotease TldD 0.39 LU632_RS21880 secB protein-export chaperone SecB low > 74
Azospirillum brasilense Sp245 0.52 AZOBR_RS10600 peptidase C69 0.33 AZOBR_RS01720 preprotein translocase subunit SecB low > 97
Rhizobium sp. OAE497 0.51 ABIE40_RS04050 metalloprotease TldD 0.35 ABIE40_RS19265 protein-export chaperone SecB low > 107
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_03522 Zn-dependent protease TldD 0.31 CCNA_03858 protein translocase subunit secB low > 67
Caulobacter crescentus NA1000 0.51 CCNA_03522 Zn-dependent protease TldD 0.31 CCNA_03858 protein translocase subunit secB low > 66
Agrobacterium fabrum C58 0.50 Atu0765 TldD 0.31 Atu0006 protein-export protein SECB
Sinorhizobium meliloti 1021 0.50 SMc00960 hypothetical protein 0.33 SMc02788 preprotein translocase subunit SecB
Rhodopseudomonas palustris CGA009 0.50 TX73_004255 metalloprotease TldD 0.33 TX73_001570 protein-export chaperone SecB low > 86
Phaeobacter inhibens DSM 17395 0.49 PGA1_c06240 protein TldD 0.29 PGA1_c35180 protein-export protein SecB

Not shown: 14 genomes with orthologs for GFF4449 only; 3 genomes with orthologs for GFF2572 only