Conservation of cofitness between ECD_00971 and ECD_00949 in Escherichia coli BL21

71 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00971 23S rRNA m(5)C1962 methyltransferase, SAM-dependent 1.0 ECD_00949 dihydro-orotate oxidase, FMN-linked low > 61
Escherichia coli BW25113 1.00 b0967 yccW predicted methyltransferase (RefSeq) 1.00 b0945 pyrD dihydroorotate dehydrogenase (NCBI) low > 76
Escherichia coli Nissle 1917 1.00 ECOLIN_RS05085 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECOR27 0.99 NOLOHH_21740 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_02699 Ribosomal RNA large subunit methyltransferase I 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 73
Escherichia coli ECOR38 0.99 HEPCGN_23335 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia coli ECRC99 0.98 KEDOAH_22550 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC100 0.98 OKFHMN_05185 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase low > 80
Escherichia coli ECRC101 0.98 MCAODC_24575 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia coli ECRC102 0.98 NIAGMN_02905 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC62 0.98 BNILDI_19905 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli ECRC98 0.98 JDDGAC_08795 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 86
Escherichia fergusonii Becca 0.98 EFB2_03104 Ribosomal RNA large subunit methyltransferase I 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Enterobacter asburiae PDN3 0.95 EX28DRAFT_1976 Predicted SAM-dependent methyltransferases 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Enterobacter sp. TBS_079 0.94 MPMX20_01617 Ribosomal RNA large subunit methyltransferase I 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF3258 LSU m5C1962 methyltransferase RlmI 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS10045 23S rRNA (cytosine(1962)-C(5))-methyltransferase 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) low > 92
Pantoea sp. MT58 0.87 IAI47_12595 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase low > 76
Serratia liquefaciens MT49 0.85 IAI46_08925 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase low > 86
Erwinia tracheiphila SCR3 0.83 LU632_RS10090 rlmI 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase low > 74
Rahnella sp. WP5 0.82 EX31_RS17990 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase low > 89
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_06820 ribosomal RNA large subunit methyltransferase I 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) low > 62
Shewanella amazonensis SB2B 0.61 Sama_2965 putative SAM-dependent methyltransferase (RefSeq) 0.62 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Shewanella sp. ANA-3 0.60 Shewana3_0977 SAM-dependent methyltransferase (RefSeq) 0.63 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) low > 73
Shewanella oneidensis MR-1 0.59 SO1149 hypothetical SAM-dependent methyltransferase (NCBI ptt file) 0.62 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.56 MIT1002_01688 Ribosomal RNA large subunit methyltransferase I 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) low > 70
Dechlorosoma suillum PS 0.48 Dsui_0653 putative SAM-dependent methyltransferase 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Ralstonia sp. UNC404CL21Col 0.48 ABZR87_RS05070 class I SAM-dependent rRNA methyltransferase 0.54 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.48 RPSI07_RS23695 class I SAM-dependent rRNA methyltransferase 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.47 RALBFv3_RS09670 class I SAM-dependent rRNA methyltransferase 0.54 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.47 UW163_RS03910 class I SAM-dependent rRNA methyltransferase 0.54 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.47 RS_RS00255 class I SAM-dependent rRNA methyltransferase 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS00350 class I SAM-dependent rRNA methyltransferase 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_02203 SAM-dependent methyltransferase /23S rRNA m(5)C-1962 methyltransferase 0.55 H281DRAFT_00743 dihydroorotate oxidase A — —
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS01650 23S rRNA methyltransferase 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase low > 109
Paraburkholderia graminis OAS925 0.45 ABIE53_000425 23S rRNA (cytosine1962-C5)-methyltransferase 0.56 ABIE53_001954 dihydroorotate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS19815 RlmI/RlmK family 23S rRNA methyltransferase 0.43 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS22040 class I SAM-dependent rRNA methyltransferase 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS01670 23S rRNA methyltransferase 0.51 RR42_RS07465 dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.40 GFF4489 23S rRNA (cytosine(1962)-C(5))-methyltransferase (EC 2.1.1.191) 0.49 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_2000 LSU m5C1962 methyltransferase RlmI 0.51 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Variovorax sp. OAS795 0.39 ABID97_RS06155 class I SAM-dependent methyltransferase 0.48 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.33 CA264_05605 RlmI/RlmK family 23S rRNA methyltransferase 0.41 CA264_00865 dihydroorotate dehydrogenase (quinone) low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.32 Echvi_3350 Predicted SAM-dependent methyltransferases 0.42 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Xanthomonas campestris pv. campestris strain 8004 0.31 Xcc-8004.5393.1 LSU m5C1962 methyltransferase RlmI 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Lysobacter sp. OAE881 0.31 ABIE51_RS00980 class I SAM-dependent rRNA methyltransferase 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Bacteroides thetaiotaomicron VPI-5482 0.31 BT4331 conserved hypothetical protein (NCBI ptt file) 0.26 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) low > 81
Dyella japonica UNC79MFTsu3.2 0.30 ABZR86_RS16890 class I SAM-dependent rRNA methyltransferase 0.50 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.29 LRK55_RS06665 class I SAM-dependent rRNA methyltransferase 0.50 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS06920 class I SAM-dependent rRNA methyltransferase 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.28 AMB_RS22065 class I SAM-dependent rRNA methyltransferase 0.36 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Azospirillum brasilense Sp245 0.27 AZOBR_RS01190 SAM-dependent methyltransferase 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase low > 97
Pseudomonas putida KT2440 0.26 PP_5127 ribosomal RNA large subunit methyltransferase I 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. S08-1 0.26 OH686_14110 23S rRNA (cytosine(1962)-C(5))-methyltransferase 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Pseudomonas sp. RS175 0.26 PFR28_04274 Ribosomal RNA large subunit methyltransferase I 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas stutzeri RCH2 0.26 Psest_0236 Predicted SAM-dependent methyltransferases 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 low > 67
Pseudomonas fluorescens FW300-N1B4 0.26 Pf1N1B4_2307 LSU m5C1962 methyltransferase RlmI 0.57 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_4764 SAM-dependent methyltransferase 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_4764 SAM-dependent methyltransferase 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_977 LSU m5C1962 methyltransferase RlmI 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS28525 class I SAM-dependent rRNA methyltransferase 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_08330 SAM-dependent methyltransferase 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_4566 LSU m5C1962 methyltransferase RlmI 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas simiae WCS417 0.26 PS417_26880 SAM-dependent methyltransferase 0.57 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.26 PFLU_RS28525 class I SAM-dependent rRNA methyltransferase 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.26 AO356_13260 SAM-dependent methyltransferase 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Marinobacter adhaerens HP15 0.26 HP15_460 SAM-dependent methyltransferase 0.47 HP15_1377 dihydroorotate dehydrogenase low > 73
Rhodanobacter sp. FW510-T8 0.26 OKGIIK_16710 rlmK RlmI/RlmK family 23S rRNA methyltransferase 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Azospirillum sp. SherDot2 0.25 MPMX19_00203 Ribosomal RNA large subunit methyltransferase I 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Rhodospirillum rubrum S1H 0.23 Rru_A3333 hypothetical protein (NCBI) 0.36 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) low > 58
Phaeobacter inhibens DSM 17395 0.20 PGA1_c19990 ribosomal RNA large subunit methyltransferase I 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD low > 62
Dinoroseobacter shibae DFL-12 0.20 Dshi_1771 hypothetical protein (RefSeq) 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) low > 64

Not shown: 10 genomes with orthologs for ECD_00971 only; 21 genomes with orthologs for ECD_00949 only