Conservation of cofitness between CSW01_00335 and CSW01_18340 in Vibrio cholerae E7946 ATCC 55056

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00335 phosphomethylpyrimidine synthase 1.0 CSW01_18340 HlyC/CorC family transporter 0.52 7
Pectobacterium carotovorum WPP14 0.76 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.56 HER17_RS03970 hemolysin family protein low > 75
Rahnella sp. WP5 0.76 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.58 EX31_RS08705 HlyC/CorC family transporter low > 89
Klebsiella pneumoniae MKP103 0.75 KDGMDA_10040 phosphomethylpyrimidine synthase ThiC 0.58 KDGMDA_11235 Polyamine export protein low > 95
Dickeya dianthicola ME23 0.75 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.56 DZA65_RS18310 HlyC/CorC family transporter low > 75
Erwinia amylovora T8 0.75 OLJFJH_06740 phosphomethylpyrimidine synthase ThiC 0.57 OLJFJH_02400 Polyamine export protein low > 58
Dickeya dadantii 3937 0.75 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.57 DDA3937_RS17170 HlyC/CorC family transporter low > 74
Erwinia tracheiphila HP pepo 2.2 0.75 IJEDHG_10885 thiC phosphomethylpyrimidine synthase ThiC 0.55 IJEDHG_06815 tlyC Polyamine export protein low > 61
Erwinia tracheiphila SCR3 0.75 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.55 LU632_RS02100 hemolysin family protein low > 73
Pantoea sp. MT58 0.75 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.57 IAI47_02710 HlyC/CorC family transporter low > 76
Escherichia coli ECOR27 0.75 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.58 NOLOHH_04280 paeA Polyamine export protein low > 76
Serratia liquefaciens MT49 0.75 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.58 IAI46_01760 HlyC/CorC family transporter low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF4198 Thiamin biosynthesis protein ThiC 0.58 GFF871 Putative membrane protein low > 78
Enterobacter sp. TBS_079 0.75 MPMX20_00217 Phosphomethylpyrimidine synthase 0.57 MPMX20_00495 hypothetical protein low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.74 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.58 OHPLBJKB_03816 hypothetical protein low > 74
Escherichia coli ECRC62 0.74 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.58 BNILDI_07240 tlyC Polyamine export protein low > 75
Escherichia coli BW25113 0.74 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.58 b4218 ytfL predicted inner membrane protein (NCBI) low > 76
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS22620 phosphomethylpyrimidine synthase ThiC 0.57 PagCFBP13505_RS11305 HlyC/CorC family transporter low > 74
Klebsiella michiganensis M5al 0.74 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.57 BWI76_RS02765 membrane protein low > 92
Escherichia coli ECRC98 0.74 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.58 JDDGAC_15655 paeA Polyamine export protein low > 87
Escherichia coli ECRC100 0.74 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.58 OKFHMN_12015 paeA Polyamine export protein low > 79
Escherichia coli ECRC101 0.74 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.58 MCAODC_02530 paeA Polyamine export protein low > 87
Dickeya dianthicola 67-19 0.74 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.56 HGI48_RS17225 HlyC/CorC family transporter low > 71
Escherichia coli Nissle 1917 0.74 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.58 ECOLIN_RS24495 hemolysin family protein low > 55
Escherichia coli BL21 0.74 ECD_03871 phosphomethylpyrimidine synthase 0.58 ECD_04089 UPF0053 family inner membrane protein low > 61
Escherichia coli ECRC102 0.74 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.58 NIAGMN_09865 paeA Polyamine export protein low > 80
Escherichia coli ECRC99 0.74 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.58 KEDOAH_16140 paeA Polyamine export protein — —
Escherichia coli ECOR38 0.74 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.58 HEPCGN_10215 paeA Polyamine export protein low > 88
Enterobacter asburiae PDN3 0.74 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.57 EX28DRAFT_3404 Hemolysins and related proteins containing CBS domains low > 76
Escherichia fergusonii Becca 0.74 EFB2_04617 Phosphomethylpyrimidine synthase 0.58 EFB2_04311 hypothetical protein low > 86
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.76 Shew_0284 hypothetical protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.79 Sama_3284 hemolysin, putative (RefSeq) low > 62
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.74 SO4351 CBS domain protein (NCBI ptt file) low > 76
Pseudomonas aeruginosa PUPa3 0.71 DQ20_RS51400 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.11 DQ20_RS49425 hemolysin family protein low > 101
Pseudomonas aeruginosa MRSN321 0.71 DY961_RS10660 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.11 DY961_RS12705 hemolysin family protein low > 100
Pseudomonas aeruginosa PA14 0.71 IKLFDK_28675 phosphomethylpyrimidine synthase ThiC 0.11 IKLFDK_26645 DUF21 domain-containing protein low > 98
Shewanella sp. ANA-3 0.71 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.73 Shewana3_0353 hypothetical protein (RefSeq) low > 73
Pseudomonas sp. SVBP6 0.69 COO64_RS17755 thiC phosphomethylpyrimidine synthase ThiC 0.10 COO64_RS01680 hemolysin family protein low > 93
Pseudomonas sp. RS175 0.69 PFR28_05091 Phosphomethylpyrimidine synthase 0.10 PFR28_04481 hypothetical protein low > 88
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.10 Pf6N2E2_4068 Phosphate regulon metal ion transporter containing CBS domains low > 103
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.10 Pf1N1B4_2042 Phosphate regulon metal ion transporter containing CBS domains low > 87
Dechlorosoma suillum PS 0.69 Dsui_0422 thiamine biosynthesis protein ThiC 0.26 Dsui_3105 CBS domain-containing protein — —
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.10 PfGW456L13_760 Phosphate regulon metal ion transporter containing CBS domains 0.27 55
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_0544 hydroxymethylpyrimidine synthase 0.11 Psyr_5034 CBS:Protein of unknown function DUF21:Transporter-associated region low > 86
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_0544 hydroxymethylpyrimidine synthase 0.11 Psyr_5034 CBS:Protein of unknown function DUF21:Transporter-associated region low > 86
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_13010 thiamine biosynthesis protein ThiC 0.10 AO353_09865 hypothetical protein 0.45 23
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.09 PFLU_RS29735 HlyC/CorC family transporter low > 109
Pseudomonas fluorescens SBW25 0.69 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.09 PFLU_RS29735 HlyC/CorC family transporter low > 109
Acinetobacter radioresistens SK82 0.68 MPMX26_00180 Phosphomethylpyrimidine synthase 0.52 MPMX26_02321 hypothetical protein low > 36
Acinetobacter baumannii LAC-4 0.68 RR41_RS17715 phosphomethylpyrimidine synthase ThiC 0.52 RR41_RS08955 hemolysin family protein low > 55
Lysobacter sp. OAE881 0.68 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.19 ABIE51_RS06575 hemolysin family protein low > 62
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.50 HSERO_RS08405 membrane protein low > 78
Dyella japonica UNC79MFTsu3.2 0.67 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.24 ABZR86_RS19900 hemolysin family protein low > 74
Rhodanobacter sp. FW510-T8 0.67 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.23 OKGIIK_02350 tlyC Hemolysin-related protein, contains CBS domains, UPF0053 family low > 53
Xanthomonas campestris pv. campestris strain 8004 0.66 Xcc-8004.1066.1 hypothetical protein 0.21 Xcc-8004.3156.1 Magnesium and cobalt efflux protein CorC low > 74
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.43 ABZR87_RS15885 hemolysin family protein low > 80
Ralstonia solanacearum GMI1000 0.65 RS_RS00555 phosphomethylpyrimidine synthase 0.42 RS_RS11430 HlyC/CorC family transporter low > 80
Cupriavidus basilensis FW507-4G11 0.65 RR42_RS01290 thiamine biosynthesis protein ThiC 0.43 RR42_RS04375 magnesium transporter low > 128
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.43 RALBFv3_RS03950 HlyC/CorC family transporter low > 76
Ralstonia solanacearum UW163 0.65 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.43 UW163_RS09720 HlyC/CorC family transporter — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.43 RPSI07_RS13270 HlyC/CorC family transporter low > 81
Variovorax sp. SCN45 0.64 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.50 GFF2520 UPF0053 inner membrane protein YtfL low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.25 GFF4625 Magnesium and cobalt efflux protein CorC low > 90
Variovorax sp. OAS795 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.50 ABID97_RS07170 hemolysin family protein low > 91
Magnetospirillum magneticum AMB-1 0.62 AMB_RS01125 phosphomethylpyrimidine synthase 0.22 AMB_RS10875 HlyC/CorC family transporter — —
Caulobacter crescentus NA1000 Δfur 0.62 CCNA_02109 thiamine biosynthesis protein thiC 0.24 CCNA_00369 magnesium and cobalt efflux protein corC-like protein low > 67
Caulobacter crescentus NA1000 0.62 CCNA_02109 thiamine biosynthesis protein thiC 0.24 CCNA_00369 magnesium and cobalt efflux protein corC-like protein low > 66
Agrobacterium fabrum C58 0.61 Atu2569 thiamine biosynthesis protein 0.20 Atu3732 hemolysin low > 89
Dinoroseobacter shibae DFL-12 0.61 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.19 Dshi_3672 protein of unknown function DUF21 (RefSeq) — —
Sinorhizobium meliloti 1021 0.61 SM_b20615 thiamine biosynthesis protein ThiC 0.26 SMc00240 hypothetical protein low > 103
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.51 Ac3H11_4775 Putative membrane protein low > 79
Brevundimonas sp. GW460-12-10-14-LB2 0.61 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.23 A4249_RS08175 hemolysin family protein low > 48
Azospirillum brasilense Sp245 0.61 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.28 AZOBR_RS16970 hypothetical protein low > 97
Xanthobacter sp. DMC5 0.61 GFF257 Phosphomethylpyrimidine synthase 0.22 GFF917 hypothetical protein — —
Azospirillum sp. SherDot2 0.59 MPMX19_00336 Phosphomethylpyrimidine synthase 0.27 MPMX19_04101 hypothetical protein low > 112
Sphingomonas koreensis DSMZ 15582 0.59 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.24 Ga0059261_1443 Hemolysins and related proteins containing CBS domains low > 68
Sphingobium sp. HT1-2 0.59 GFF941 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.24 GFF2484 Hemolysins and related proteins containing CBS domains low > 95
Rhodopseudomonas palustris CGA009 0.59 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.21 TX73_014560 hemolysin family protein low > 86
Rhodanobacter sp000427505 FW510-R12 0.58 LRK53_RS03795 phosphomethylpyrimidine synthase ThiC 0.20 LRK53_RS15625 hemolysin family protein low > 59
Bosea sp. OAE506 0.58 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.19 ABIE41_RS13905 hemolysin family protein low > 77
Rhodospirillum rubrum S1H 0.56 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.25 Rru_A0756 hypothetical protein (NCBI) low > 58
Phocaeicola vulgatus CL09T03C04 0.55 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.20 HMPREF1058_RS12080 HlyC/CorC family transporter low > 67
Phocaeicola dorei CL03T12C01 0.55 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.20 ABI39_RS04720 HlyC/CorC family transporter low > 72
Parabacteroides merdae CL09T00C40 0.55 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.24 HMPREF1078_RS00430 hemolysin family protein low > 61
Bacteroides thetaiotaomicron VPI-5482 0.55 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.23 BT0148 putative hemolysin (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.55 BACOVA_02358 thiamine biosynthesis protein ThiC 0.22 BACOVA_01289 hypothetical protein low > 96
Bacteroides stercoris CC31F 0.55 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.21 HMPREF1181_RS05310 HlyC/CorC family transporter low > 56

Not shown: 25 genomes with orthologs for CSW01_00335 only; 9 genomes with orthologs for CSW01_18340 only